Drugs online research references
J Pharmacol Exp Ther. 2001 Mar;296(3):789-96.
Titer-dependent antagonism of cocaine following active immunization in rhesus monkeys.
Koetzner L, Deng S, Sumpter TL, Weisslitz M, Abner RT, Landry DW, Woods JH.
Department of Pharmacology, University of Michigan, Ann Arbor, Michigan 48109-0632, USA.
Immunization may be a useful pharmacokinetic antagonist therapy for cocaine users. Three rhesus monkeys were immunized with a cocaine:bovine serum albumin conjugate in alum and later with complete and incomplete Freund's adjuvants. Monkeys developed cocaine-binding antibodies (as measured by enzyme-linked immunosorbent assay) after immunization with alum; greater antibody titers developed after immunization with Freund's adjuvants. The response rate-decreasing effect of cocaine diminished in proportion to antibody titer; there was no substantial change in the rate-decreasing effect of bupropion. Plasma cocaine concentrations increased in proportion to antibody titer. Immunizations were well tolerated and had no effect on response rates. These data suggest that the antibody response to a cocaine antigen can produce a specific pharmacokinetic shift in cocaine distribution sufficient to antagonize a behavioral effect of the drug, and can do so with minimal side effects.
online pharmacy ref source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11181908&dopt=Abstract
word match zyban online literature
Health Serv J. 2001 Feb 15;111(5742):30-1.
Smoking cessation. Pulling out the stops.
Langdon M, Richardson W, Campion P, Madhok R.
Department of Public Health and Primary Care, Hull University.
The launch of smoking-cessation drug Zyban in June last year greatly increased demand on a local smoking-cessation service. It is important to use local media to increase awareness of local services. Health authorities and pharmaceutical companies should work with the media when new drugs may put extra strain on local services.
online pharmacy ref source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11246826&dopt=Abstract
word match zyban online literature
W V Med J. 2001 Jan-Feb;97(1):39-43.
Treating nicotine dependence.
Glover ED, Glover PN.
Tobacco Research Center, Mary Babb Randolph Cancer Center, West Virginia University School of Medicine, Morgantown, USA.
To explore the biology of nicotine addiction and to discuss the latest effective treatments for nicotine dependence. Research indicates that the most effective methods for treating nicotine dependence are nicotine replacement therapy (NRT) and bupropion SR (BUP). We conclude that pharmacological adjuncts (NRT & BUP) achieve their greatest success when combined with behavioral counseling.
online pharmacy ref source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11257836&dopt=Abstract
word match zyban online literature
Herbs and Pharmaceuticals Online ||
Hair Million herbal formula for hair loss and hair growth ||
Antibiotics and prescription medications online literature ||