Drugs online research references
Psychiatr Q. 1998 Summer;69(2):117-25.
Black and white patients response to antidepressant treatment for major depression.
Varner RV, Ruiz P, Small DR.
Department of Psychiatry and Behavioral sciences of the University of Texas/Houston Health Science Center, USA.
Differences in response to psychopharmacologic agents according to race has so far primarily focused on investigations related to the response of Asian-American patients to neuroleptics and lithium. In this article, we present evidence which depicts that black patients need lower doses of tricyclic antidepressants (TCAs) than white patients to attain a similar response in the treatment of major depression. Likewise, we also advance that black patients might need lower doses of selective serotonin re-uptake inhibitor antidepressants (SSRIs) than white patients to attain a similar response in the treatment of major depression. Further studies are suggested to confirm these findings.
online pharmacy ref source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9627929&dopt=Abstract
word match zoloft online literature
Zh Vyssh Nerv Deiat Im I P Pavlova. 1998 Mar-Apr;48(2):348-51.
[The place of the action of the serotoninergic system in the 2-stage process of the formation of latent inhibition in rats]
[Article in Russian]
Loskutova LV.
Institute of Physiology, Russian Academy of Medical Sciences, Siberian Branch, Novosibirsk.
Activation of rat brain serotonergic system (injections of a selective serotonin reuptake blocker sertralin) at the stage of pre-exposition of the situation stimulus (placing into the illuminated compartment of the dark-light shuttle-box) intensified subsequent development of the latent inhibition at the stage of conditioning, which was measured by the latent period of transition to the dark compartment during the first testing after reinforcement of such transition with electrical shock.
online pharmacy ref source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9644816&dopt=Abstract
word match zoloft online literature
J Am Acad Child Adolesc Psychiatry. 1998 Jul;37(7):777-84.
Platelet serotonin transporter in depressed children and adolescents: 3H-paroxetine platelet binding before and after sertraline.
Sallee FR, Hilal R, Dougherty D, Beach K, Nesbitt L.
Medical University of South Carolina, Charleston, USA.
OBJECTIVE: To evaluate serotonin transporter protein (5HTPR) binding in platelets from children and adolescents with major depression (MDD) compared to normal controls using the selective ligand 3H-paroxetine. METHOD: Children and adolescents with MDD (n = 24) defined by DSM-III-R criteria and normal controls (n = 22) were compared by platelet 5HTPR kinetic analysis with the hypothesis that 5HTPR is reduced in MDD. A subset of MDD subjects (n = 18) continued to participate in a fixed-dose, open-label sertraline trial for 6 weeks followed by drug-free washout and repeated 5HTPR analysis. RESULTS: Sex, prepubertal status, and age had no effect on 5HTPR. Medication-free MDD subjects differed from controls in reduced binding capacity (Bmax) (p < .001). Sertraline therapy decreased binding affinity from baseline non-selectively (p < .05), and Bmax elevation from baseline was associated with nonresponse and suicide attempt history. CONCLUSION: Earlier literature in this population is replicated with regard to reduced platelet 5HTPR Bmax in MDD. Findings support a continuum of 5HTPR involvement in MDD across the developmental spectrum.
online pharmacy ref source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9666634&dopt=Abstract
word match zoloft online literature
Herbs and Pharmaceuticals Online ||
Hair Million herbal formula for hair loss and hair growth ||
Antibiotics and prescription medications online literature ||