Zestril online research references









  • Angiotensin converting enzyme inhibition in heart, kidney, and serum studied ex vivo after administration of zofenopril, captopril, and lisinopril.
  • Inhibitory activity and protein binding of L-lysine derivatives as angiotensin converting enzyme inhibitors.
  • A deeply recessed active site in angiotensin-converting enzyme is indicated from the binding characteristics of biotin-spacer-inhibitor reagents.
  • The role of tissue renin-angiotensin systems in hypertension and effects of chronic converting-enzyme inhibition.
  • Preferential biliary elimination of FPL 63547, a novel inhibitor of angiotensin-converting enzyme, in the rat.
  • Regional haemodynamic effects of captopril, enalaprilat and lisinopril in conscious water-replete and water-deprived Brattleboro rats.
  • Effects of an angiotensin converting enzyme (ACE) inhibitor on plasma endorphin level.
  • Isolation of angiotensin converting enzyme (ACE) binding protein from human serum with an ACE affinity column.
  • Treatment of hypertension with lisinopril in end-stage renal failure.
  • The antihypertensive response to lisinopril: the effect of age in a predominantly black population.
  • Predictive value of ambulatory blood pressure shortly after withdrawal of antihypertensive drugs in primary care patients.
  • Changes in dyspnea-fatigue ratings as indicators of quality of life in the treatment of congestive heart failure.
  • Antihypertensive effect of repeated oral administration of MK-0521 in 2-kidney Goldblatt hypertensive dogs
  • Pharmacokinetics of enalapril and lisinopril in subjects with normal and impaired hepatic function.
  • Dose of doxorubicin determines severity of renal damage and responsiveness to ACE-inhibition in experimental nephrosis.
  • Intestinal absorption mechanism of dipeptide angiotensin converting enzyme inhibitors of the lysyl-proline type: lisinopril and SQ 29,852.
  • Blockade of angiotensin converting enzyme in circumventricular organs of the brain after oral lisinopril administration demonstrated by quantitative in vitro autoradiography.
  • Population pharmacokinetics of lisinopril in hypertensive patients.
  • Direct radio-immunoassay of renin substrate: effect of converting enzyme inhibition.
  • Effects of angiotensin-converting enzyme (ACE) inhibitors on oxygen radical production and generation by murine lung alveolar macrophages.
  • Altered angiotensin-converting enzyme in lung and extrapulmonary tissues of hypoxia-adapted rats.
  • Time-resolved fluoroimmunoassay for the determination of lisinopril and enalaprilat in human serum.
  • Antihypertensive efficacy of lisinopril. Ambulatory blood pressure monitoring.
  • Antihypertensive and renal effects of lisinopril in older patients with hypertension.
  • Effects of the angiotensin converting enzyme inhibitor, lisinopril, on normal and diabetic rats.
  • Delayed tolerance to furosemide diuresis. Influence of angiotensin converting enzyme inhibition by lisinopril.
  • Pharmacokinetics of lisinopril, enalapril and enalaprilat in renal failure: effects of haemodialysis.
  • Differential renal handling of angiotensin-converting enzyme inhibitors enalaprilat and lisinopril in rats.
  • Acute and chronic effects of the converting enzyme inhibitors enalapril and lisinopril on reflex control of heart rate in normotensive man.
  • Acute hemodynamic and hormonal effects of lisinopril (MK-521) in congestive heart failure.
  • Lack of angiotensin I accumulation after converting enzyme blockade by enalapril or lisinopril in man.
  • Lisinopril in hypertensive patients with and without renal failure.
  • In vivo comparison between two tip pressure transducer systems.
  • Distribution of angiotensin converting enzyme in sheep hypothalamus and medulla oblongata visualized by in vitro autoradiography.
  • Acute hemodynamic and hormonal effects of MK-521 in congestive heart failure.
  • Enalapril maleate and a lysine analogue (MK-521) in normal volunteers; relationship between plasma drug levels and the renin angiotensin system.
  • Initial evaluation of the non-sulfhydryl-containing converting enzyme inhibitor MK-521 in hypertensive humans.
  • Comparable effects of angiotensin II and converting enzyme blockade on hemodynamics and cardiac hypertrophy in spontaneously hypertensive rats.
  • Comparison of effects of angiotensin-converting enzyme inhibition with those of angiotensin II receptor antagonism on functional and metabolic recovery in postischemic working rat heart as studied by 31P nuclear magnetic resonance.
  • Protein synthesis in the hypertrophied heart of spontaneously hypertensive rats and a comparison of the effects of an ACE-inhibitor and a calcium channel antagonist.
  • Effects of an early treatment with lisinopril and isosorbide-5-mononitrate on hemodynamics and late ventricular remodelling in rats with 9-week myocardial infarction.
  • Inhibition of angiotensin-converting enzyme and attenuation of myocardial fibrosis by lisinopril in rats receiving angiotensin II.
  • Sympathetic nerve activity in conscious renal hypertensive rats treated with an angiotensin converting enzyme inhibitor or an angiotensin II antagonist.
  • Pharmacokinetic-pharmacodynamic model relating lisinopril plasma concentrations to regional hemodynamic effects in healthy volunteers.
  • Effect of angiotensin converting enzyme inhibitor (lisinopril) on insulin sensitivity and sodium transport in mild hypertension.
  • Effects of blocking the angiotensin II receptor, converting enzyme, and renin activity on the renal hemodynamics of normotensive guinea pigs.
  • Effect of chronic ACE inhibition on the diagnostic value of renography for renovascular hypertension: a preliminary report.
  • Prevention of angiotensin II induced myocyte necrosis and coronary vascular damage by lisinopril and losartan in the rat.
  • Angiotensin II receptor binding following myocardial infarction in the rat.
  • Mutations in two specific residues of testicular angiotensin-converting enzyme change its catalytic properties.
  • Effects of different antihypertensive treatments on morphologic progression of diabetic nephropathy in uninephrectomized dogs.
  • Evidence for stimulation of neutrophil degranulation by selected angiotensin converting enzyme inhibitors in vitro.
  • Increased arterial distensibility induced by the angiotensin-converting enzyme inhibitor, lisinopril, in normotensive rats.
  • ACE inhibitors and cough.
  • Valvular interstitial cells express angiotensinogen and cathepsin D, and generate angiotensin peptides.
  • Effects of converting enzyme inhibitors on angiotensin and bradykinin peptides.
  • Structural constraints of inhibitors for binding at two active sites on somatic angiotensin converting enzyme.
  • Vasomotor responses in cyclosporin A-treated rats after chronic angiotensin blockade.
  • Effects of lisinopril and captopril on calcium in rat heart.
  • Angiotensin(1-7) in the spontaneously hypertensive rat.
  • Dyspnoea, asthma, and bronchospasm in relation to treatment with angiotensin converting enzyme inhibitors.
  • Drug-induced, life-threatening angioedema revisited.
  • Role of nitric oxide and angiotensin II in the regulation of sympathetic nerve activity in spontaneously hypertensive rats.
  • Lisinopril reduces cardiac hypertrophy and mortality in rats with aortocaval fistula.
  • Lisinopril use in a large military medical center.
  • Early versus delayed angiotensin-converting enzyme inhibition in experimental chronic heart failure. Effects on survival, hemodynamics, and cardiovascular remodeling.
  • Effects of chronic treatment with lisinopril on cardiovascular complications in streptozotocin diabetic and DOCA hypertensive rats.
  • Involvement of 5-hydroxytryptamine and bradykinin in the hyperalgesia induced in rats by collagenase from Clostridium histolyticum.
  • Cultured myofibroblasts generate angiotensin peptides de novo.
  • Presence and comparison of angiotensin converting enzyme in commercial cell culture sera.
  • Free radical scavenging properties of alacepril metabolites and lisinopril.
  • ACE polymorphism does not determine short-term renal response to ACE-inhibition in proteinuric patients.
  • Combination antihypertensive drugs: recommendations for use.
  • Angiotensin-converting enzyme and neutral endopeptidase modulate smokeless tobacco-induced increase in macromolecular efflux from the oral mucosa in vivo.
  • Absence of tachykinin involvement in leukotriene D4 and antigen-induced contraction of guinea pig isolated bronchus.
  • Sheep testicular and epididymal angiotensin converting enzyme: inhibitions by captopril, lisinopril and enalapril.
  • Effect of lisinopril on cardiac parameters and mortality after myocardial infarction in rats
  • Vasodepressor actions of angiotensin-(1-7) unmasked during combined treatment with lisinopril and losartan.
  • Effects of long-term antihypertensive treatment with lisinopril on resistance arteries in hypertensive patients with left ventricular hypertrophy.
  • Calorimetric analysis of lisinopril binding to angiotensin I-converting enzyme.
  • Control of hyperinsulinemia in essential hypertension using the angiotensin-converting enzyme inhibitor, lisinopril
  • Early rather than delayed administration of lisinopril protects the heart after myocardial infarction in rats.
  • Reversal of heart failure remodeling in women.
  • Significant role of the increase in renin-angiotensin system in cardiac hypertrophy and renal glomerular sclerosis in double transgenic tsukuba hypertensive mice carrying both human renin and angiotensinogen genes.
  • Tissue availability of insulin-like growth factor I is inversely related to insulin resistance in essential hypertension: effects of angiotensin converting enzyme inhibition.
  • Hospital intensive monitoring of adverse reactions of ACE inhibitors
  • Pouch tissue and angiotensin peptide generation.
  • Converting enzyme determines plasma clearance of angiotensin-(1-7).
  • Effects of lisinopril and amlodipine on antioxidant status in experimental hypertension.
  • The renin-angiotensin system in hybrid NG108-15 cells. Renin gene is from mouse neuroblastoma, angiotensinogen and angiotensin-converting enzyme genes are of rat glioma origin.
  • Endogenous angiotensin II and the reflex response to stimulation of cardiopulmonary serotonin 5HT3 receptors.
  • Effects of lisinopril on experimental ischemia in rats. Influence of infarct size.
  • Exclusion of angiotensin I-converting enzyme as a candidate gene involved in exudative inflammatory resistance in F344/N rats.
  • Poor regression of myocardial hypertrophy following concomitant chronic alcohol ingestion and angiotensin converting enzyme (ACE) inhibition.
  • Apoptosis of lung epithelial cells in response to TNF-alpha requires angiotensin II generation de novo.
  • Angiotensin I-converting enzyme transition state stabilization by HIS1089: evidence for a catalytic mechanism distinct from other gluzincin metalloproteinases.
  • Lisinopril reduces left ventricular hypertrophy and cardiac polyamine concentrations without a reduction in left ventricular wall stress in transgenic Tsukuba hypertensive mice.
  • In vivo protein synthetic rates of atrial, ventricular, and pulmonary tissue proteins in aortic constriction, goldblatt, and bromoethylamine models of hypertension.
  • Late escape from the antiproteinuric effect of ace inhibitors in nondiabetic renal disease.
  • Angiotensin-converting enzyme inhibitor dosages in elderly patients with heart failure.
  • Dobutamine as bridge to angiotensin-converting enzyme inhibitor-nitrate therapy in endstage heart failure.
  • Angiogenesis induced by electrical stimulation is mediated by angiotensin II and VEGF.
  • Rapid reversal of a motor nerve conduction deficit in streptozotocin-diabetic rats by the angiotensin converting enzyme inhibitor lisinopril.
  • RXP 407, a selective inhibitor of the N-domain of angiotensin I-converting enzyme, blocks in vivo the degradation of hemoregulatory peptide acetyl-Ser-Asp-Lys-Pro with no effect on angiotensin I hydrolysis.
  • Suppression of experimental abdominal aortic aneurysms in the rat by treatment with angiotensin-converting enzyme inhibitors.
  • Effect of angiotensin-converting enzyme inhibition on sympathetic tone in patients with mild to moderate heart failure.
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  • Characterization of bovine atrial angiotensin-converting enzyme.
  • The influence of the ACE inhibitor lisinopril on the glomerular metabolism of proteolytic enzymes in diabetic rats.
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  • Fluorescence polarization studies of different forms of angiotensin-converting enzyme.
  • Differential response of angiotensin peptides in the urine of hypertensive animals.
  • Serum and urinary magnesium during treatment of patients with chronic congestive heart failure.
  • Stimulation of bradykinin B(1) receptors induces vasodilation in conductance and resistance coronary vessels in conscious dogs: comparison with B(2) receptor stimulation.
  • The role of angiotensin II in regulating catecholamine secretion during hypoxia in rainbow trout Oncorhynchus mykiss.
  • PH-dependent coordination of metal-lisinopril complex investigated by attenuated total reflection/Fourier transform infrared spectroscopy.
  • Effects of aminopeptidase P inhibition on kinin-mediated vasodepressor responses.
  • Beneficial effects of angiotensin-converting enzyme inhibition in adriamycin-induced cardiomyopathy in hamsters.
  • Transforming growth factor-beta(1) induces angiotensin-converting enzyme synthesis in rat cardiac fibroblasts during their differentiation to myofibroblasts.
  • Blockade of angiotensin AT1a receptor signaling reduces tumor growth, angiogenesis, and metastasis.
  • Medicamentous kidney protection in type 2 diabetic patients--is cheaper also more economical? A model calculation for Swiss health care
  • Differential effects of the angiotensin-converting enzyme inhibitor lisinopril versus the beta-adrenergic receptor blocker atenolol on hemodynamics and left ventricular contractile function in experimental mitral regurgitation.
  • Effect of angiotensin-converting enzyme inhibitors on liver regeneration in rats.
  • Captopril and quinapril reduce reactive oxygen species.
  • Regulation of renin-angiotensin system in unilateral ureteral obstruction.
  • Inhibition of TGFbeta1 by anti-TGFbeta1 antibody or lisinopril reduces thyroid fibrosis in granulomatous experimental autoimmune thyroiditis.
  • Competitive inhibition of glycylsarcosine transport by enalapril in rabbit renal brush border membrane vesicles: interaction of ACE inhibitors with high-affinity H+/peptide symporter.
  • Comparison of the cardiovascular protection by omapatrilat and lisinopril treatments in DOCA-salt hypertension.
  • A new spectrofluorimetric method for the determination of lisinopril in tablets.
  • ANG II is involved in the LPS-induced production of proinflammatory cytokines in dehydrated rats.
  • Effects of anti-proteinuric therapy with angiotensin-converting-enzyme inhibition on renal protein catabolism in the adriamycin-induced nephrotic rat.
  • Anti-oxidative properties of beta-blockers and angiotensin-converting enzyme inhibitors in congestive heart failure.
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  • Effect of lisinopril and isosorbide-5-mononitrate on hemodynamics and mortality in rats with permanent coronary artery occlusion.
  • Structural basis of the lisinopril-binding specificity in N- and C-domains of human somatic ACE.
  • A comparison of the effect of angiotensin converting enzyme inhibition and angiotensin II receptor antagonism on the structural changes associated with hypertension in rat small arteries.
  • Manipulations of the renin-angiotensin system and intake of a sweetened alcoholic beverage among rats.
  • Angioneurotic edema caused by angiotensin-converting enzyme inhibitors
  • Effects of angiotensin converting enzyme inhibition in adult polycystic kidney disease.
  • Angioedema associated with lisinopril.
  • Impact of angiotensin converting enzyme inhibition on the haemodynamic profile during laboratory stress tests.
  • Mixed-type inhibition of bovine lung angiotensin converting enzyme by lisinopril and its dansyl derivative.
  • Acute and chronic effects of angiotensin-converting enzyme inhibitors on tissue angiotensin-converting enzyme.
  • Enhanced blood pressure and renal hemodynamic effect of chronic versus acute lisinopril administration in the rabbit.
  • Converting-enzyme inhibitors increase converting-enzyme mRNA and activity in endothelial cells.
  • ACE inhibitors and vagal activity: the effect of captopril and lisinopril on cardiovascular reflexes
  • Antiproteinuric effect predicts renal protection by angiotensin-converting enzyme inhibition in rats with established adriamycin nephrosis.
  • Effectiveness of the antihypertensive action of lisinopril on left ventricular mass and diastolic filling.
  • Autocrine angiotensin system regulation of bovine aortic endothelial cell migration and plasminogen activator involves modulation of proto-oncogene pp60c-src expression.
  • Endothelin, but not angiotensin II, contributes to the hypoxic contractile response of large isolated pulmonary arteries in the rat.
  • Effects of angiotensin II and angiotensin converting enzyme inhibitors on contractile and growth responses in isolated carotid arteries of the rat.
  • Angiotensin-converting enzyme: zinc- and inhibitor-binding stoichiometries of the somatic and testis isozymes.
  • Measurement of angiotensin converting enzyme induction and inhibition using quantitative in vitro autoradiography: tissue selective induction after chronic lisinopril treatment.
  • Pathogenetic role of vascular angiotensin-converting enzyme in the spontaneously hypertensive rat.
  • Characterisation of 3Hceranapril recognition sites in rat and human brain tissue.
  • Hypotensive effects of angiotensin II analogues and angiotensin converting enzyme inhibitors in water-deprived Brattleboro rats.
  • Pharmacokinetics and antihypertensive effects of lisinopril in hypertensive patients with normal and impaired renal function.
  • Effects of lisinopril on the structure of renal arterioles.







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