Tramadol online research references









  • Tramadol and seizures: a surveillance study in a managed care population.
  • The antinociceptive effect of tramadol on a model of neuropathic pain in rats.
  • Direct tramadol application on sciatic nerve inhibits spinal somatosensory evoked potentials in rats.
  • Effects of tramadol on experimental inflammation.
  • Influence of tramadol on morphine discriminative behavior in rats.
  • Tramadol in the treatment of pain
  • Gas chromatographic method using nitrogen-phosphorus detection for the measurement of tramadol and its O-desmethyl metabolite in plasma and brain tissue of mice and rats.
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  • Concordance between tramadol and dextromethorphan parent/metabolite ratios: the influence of CYP2D6 and non-CYP2D6 pathways on biotransformation.
  • Direct chiral assay of tramadol and detection of the phase II metabolite O-demethyl tramadol glucuronide in human urine using capillary electrophoresis with laser-induced native fluorescence detection.
  • Labelling studies for structure elucidation of a new hydroxymetabolite of tramadol.
  • Tramadol has no effect on cortical renal blood flow--despite increased serum catecholamine levels--in anesthetized rats: implications for analgesia in renal insufficiency.
  • Influence of oral tramadol on the dynamic ventilatory response to carbon dioxide in healthy volunteers.
  • Comparison of nerve conduction blocks by an opioid and a local anesthetic.
  • Isobolographic analysis of the analgesic interactions between ketamine and tramadol.
  • Effect of acute and chronic tramadol on 3H-norepinephrine-uptake in rat cortical synaptosomes.
  • The antinociceptive effect of tramadol in the formalin test is mediated by the serotonergic component.
  • The analgesic drug tramadol prevents the effect of surgery on natural killer cell activity and metastatic colonization in rats.
  • Selegiline: a second look. Six years later: too risky in Parkinson's disease.
  • The inhibitory effects of tramadol on muscarinic receptor-induced responses in Xenopus oocytes expressing cloned M(3) receptors.
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  • Actions of drugs affecting the cough reflex
  • Tramadol reduces the 5-HTP-induced head-twitch response in mice via the activation of mu and kappa opioid receptors.
  • Effect of droperidol and tramadol combination on the hemostasis in rabbits
  • Pharmacokinetic/pharmacodynamic modeling of the antinociceptive effects of (+)-tramadol in the rat: role of cytochrome P450 2D activity.
  • Patient reporting of adverse drug reactions: useful information for pain management?
  • Pharmacokinetics of oral tramadol drops for postoperative pain relief in children aged 4 to 7 years--a pilot study.
  • Post-surgical paediatric pain: Nursing- PCA vs continuous I.V. infusion of tramadol
  • Tramadol inhibits rat detrusor overactivity caused by dopamine receptor stimulation.
  • Therapy with opioids in liver or renal failure
  • Actions of tramadol on micturition in awake, freely moving rats.
  • Chemoembolization for hepatocellular carcinoma: effect of intraarterial lidocaine in peri- and post-procedural pain and hospitalization.
  • Microencapsulation and characterization of tramadol-resin complexes.
  • Lornoxicam, a new potent NSAID with an improved tolerability profile.
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  • HPLC method for determination of tramadol hydrochloride in human plasma
  • Interaction between metamizol and tramadol in a model of acute visceral pain in rats.
  • Opioid and nonopioid components independently contribute to the mechanism of action of tramadol, an 'atypical' opioid analgesic.
  • 11C-labelling of the analgesic tramadol and its major metabolites by selective O- and N-methylation.
  • The metabolism of tramadol by human liver microsomes.
  • Effects of tramadol on rat detrusor overactivity induced by experimental cerebral infarction.
  • Stereoselectivity in biliary excretion of trans tramadol and trans O-demethyltramadol in rats
  • Stapled hemorrhoidectomy for the treatment of hemorrhoids.
  • Analysis of behavioural and physiological parameters for the assessment of postoperative analgesic demand in newborns, infants and young children: a comprehensive report on seven consecutive studies.
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  • Non-steroidal anti-inflammatory drugs antagonise the constipating effects of tramadol.
  • Patient-controlled analgesia with tramadol and tramadol/droperidol mixture after abdominal hysterectomy: a double-blinded, randomized controlled trial
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  • Tramadol versus buprenorphine for the treatment of opiate withdrawal: a retrospective cohort control study.
  • A monoblock resection for malignant phaeochromocytoma.
  • Analysis of the analgesic interactions between ketorolac and tramadol during arthritic nociception in rat.
  • Introduction: Methods, Commentary, and Summary.
  • Use of tramadol versus pethidine versus denaverine suppositories in labor--a contribution to noninvasive therapy of labor pain
  • Analgesia after orthopedic interventions
  • Tramadol/Acetaminophen combination tablets for the treatment of pain associated with osteoarthritis flare in an elderly patient population.
  • The effect of microinjections of morphine and tramadol into the locus coeruleus on the nociceptive responses of the spinal cord neurons and on shifts in the arterial pressure
  • Effects of the analgesic agent tramadol in normal and arthritic rats: comparison with the effects of different opioids, including tolerance and cross-tolerance to morphine.
  • The effect of flupirtine, various analgesics and muscle relaxants on skeletal muscle tone in the conscious rat
  • Autonomic nervous system and gastric stress in rats
  • Analgesic effect of tramadol in the rat.
  • Comparative physical dependence studies in rats with flupirtine and opiate receptor stimulating analgesics.
  • General pharmacological studies on tramadol, a potent analgetic agent
  • Effects of tramadol on motor and sensory responses of the spinal nociceptive system in the rat.
  • Effect of analgesic drugs on the electromyographic activity of the gastrointestinal tract and sphincter of Oddi and on biliary pressure.
  • Anticonvulsant and proconvulsant effects of tramadol, its enantiomers and its M1 metabolite in the rat kindling model of epilepsy.
  • Tramadol infusion anesthesia with the substitution of enflurane and various nitrous oxide concentrations
  • The therapeutic system, CODIC
  • Algo-pupillometric investigation of the analgesic effect of tramadol
  • Direct determination of tramadol glucuronides in human urine by high-performance liquid chromatography with fluorescence detection.
  • Choice of a central analgesic for anesthesia with spontaneous respiration
  • Effects of tramadol on haemodynamics and blood gases in the early postoperative period
  • Biotransformation of tramadol in man and animal
  • First year's experience with an acute pain service--University Hospital Kuala Lumpur.
  • A clinical-experimental study of narcotic properties of opiate receptor agonists-antagonists and experience in their use in drug addiction practice
  • Inhibition of spinal noradrenaline uptake in rats by the centrally acting analgesic tramadol.
  • Assay of tramadol in urine by capillary electrophoresis using laser-induced native fluorescence detection.
  • Withdrawal characteristics following frequent intravenous administration of several opioids in rats
  • Analysis of tramadol and its metabolites in human urine
  • Effects of the central analgesic tramadol on the uptake and release of noradrenaline and dopamine in vitro.
  • Postoperative analgesia with epidural administration of a combination of tramadol and clonidine
  • Galanin receptor antagonists attenuate spinal antinociceptive effects of DAMGO, tramadol and non-opioid drugs in rats.
  • High-performance liquid chromatographic assay for the simultaneous determination of tramadol and its metabolites in microsomal fractions of human liver.
  • Determination of tramadol in human plasma by capillary gas chromatography-mass spectrometry using solid-phase extraction.
  • Effect of acute and chronic tramadol on 3H-5-HT uptake in rat cortical synaptosomes.
  • Automated determination of tramadol enantiomers in human plasma using solid-phase extraction in combination with chiral liquid chromatography.
  • Identification of tramadol and its metabolites in blood from drug-related deaths and drug-impaired drivers.
  • Enantiomeric determination of tramadol and its main metabolite O-desmethyltramadol in human plasma by liquid chromatography-tandem mass spectrometry.
  • Determination of cis and trans isomers of tramadol hydrochloride by capillary zone electrophoresis.
  • Enantiomeric separation of tramadol hydrochloride and its metabolites by cyclodextrin-mediated capillary zone electrophoresis.
  • Treatment of pain with sustained-release tramadol 100, 150, 200 mg: results of a post-marketing surveillance study.
  • Tramadol reduces the sweating, vasoconstriction, and shivering thresholds.
  • Effects of tramadol stereoisomers on norepinephrine efflux and uptake in the rat locus coeruleus measured by real time voltammetry.
  • Results of a survey of anesthetists on postoperative nausea and vomiting
  • Determination of common drugs of abuse in body fluids using one isolation procedure and liquid chromatography--atmospheric-pressure chemical-ionization mass spectromery.
  • Laparoscopic surgery of varicocele. Role of total endovenous anesthesia in same-day discharge







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