Drugs online research references











  • Gastric mucosal apoptosis induced by ethanol: effect of antiulcer agents.
  • Gastric mucosal changes induced by long term infection with Helicobacter pylori in Mongolian gerbils: effects of bacteria eradication.
  • Helicobacter pylori infection in a pediatric population: in vitro susceptibilities to omeprazole and eight antimicrobial agents.
  • Reproducibility, validity, and responsiveness of a disease-specific symptom questionnaire for gastroesophageal reflux disease.
  • Enhancement of neutrophil infiltration in the corpus after failure of Helicobacter pylori eradication.
  • Omeprazole, a specific inhibitor of gastric (H+-K+)-ATPase, is a H+-activated oxidizing agent of sulfhydryl groups.
  • The effects of NorA inhibition on the activities of levofloxacin, ciprofloxacin and norfloxacin against two genetically related strains of Staphylococcus aureus in an in-vitro infection model.
  • Effects of 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid, an inhibitor of Cl(-)-HCO3- exchanger, on stress-induced gastric lesions in rats.
  • Proton pump inhibitor-associated gastric polyps: a retrospective analysis of their frequency, and endoscopic, histologic, and ultrastructural characteristics.
  • Differentiation among inhibitory actions of omeprazole, cimetidine, and SCN- on gastric acid secretion.
  • Relationship between eradication therapy and clarithromycin-resistant Helicobacter pylori in Japan.
  • Effect of proton pump inhibitors on the detection of Helicobacter pylori in gastric biopsies.
  • Effects of a proton pump inhibitor, AG-1749 (lansoprazole), on reflux esophagitis and experimental ulcers in rats.
  • Effect of omeprazole, an inhibitor of H+,K(+)-ATPase, on bone resorption in humans.
  • Omeprazole, a proton pump inhibitor, reduces the secretion, synthesis and gene expression of pepsinogen in the rat stomach.
  • Species comparison in P450 induction: effects of dexamethasone, omeprazole, and rifampin on P450 isoforms 1A and 3A in primary cultured hepatocytes from man, Sprague-Dawley rat, minipig, and beagle dog.
  • Importance of gastric acid in gastric ulcer formation in rabbits with antibody-induced prostaglandin deficiency.
  • Possible mechanism for the inhibition of gastric (H+ + K+)-adenosine triphosphatase by the proton pump inhibitor AG-1749.
  • Mechanisms of acid release in isolated gas gland cells of the European eel Anguilla anguilla.
  • Omeprazole and ranitidine, antisecretagogues with different modes of action, are equally effective in causing hyperplasia of enterochromaffin-like cells in rat stomach.
  • An evaluation of the CYP1A induction potential of pantoprazole in primary rat hepatocytes: a comparison with other proton pump inhibitors.
  • Interaction of drugs for eradication therapy against antibiotic-resistant strains of Helicobacter pylori.
  • Antiulcer drug prescribing in hospital successfully influenced by "immediate concurrent feedback".
  • Effect of omeprazole on interdigestive gastroduodenal motility of patients with ulcer-like dyspepsia.
  • Serum pepsinogens after interruption of long-term maintenance therapy with omeprazole in patients with reflux esophagitis.
  • Effect of omeprazole on intestinal output in the short bowel syndrome.
  • Role of 24 hour intraesophageal pH monitoring in diagnosis of gastroesophageal reflux and assessment of drug effectiveness
  • Effect of omeprazole on intragastric and duodenal bulb acidity in duodenal ulcer patients.
  • Pharmacokinetics of intravenous omeprazole in children.
  • Effect of once daily intravenous and oral omeprazole on 24-hour intragastric acidity in healthy subjects.
  • Contribution of cytosolic ionic and energetic milieu change to ischemia- and reperfusion-induced injury in guinea pig heart: fluorometry and nuclear magnetic resonance studies.
  • Determination of omeprazole in rat plasma by HPLC with column switching.
  • Bleeding from staple line erosion after esophageal transection: effect of omeprazole.
  • Application of proton pump inhibitor to special conditions; Zollinger-Ellison syndrome
  • Studies on (H(+)-K+)-ATPase inhibitors of gastric acid secretion. Prodrugs of 2-(2-pyridinylmethyl)sulfinylbenzimidazole proton-pump inhibitors.
  • Effect of an H+, K+-ATPase inhibitor, omeprazole (OPZ), on gastric acid secretion and gastric or duodenal lesion. Comparison with an H2-receptor antagonist, famotidine (FMD)
  • Intracellular binding is an important determinant of the avid hepatic uptake of the high clearance drug omeprazole.
  • Structure of 5-methoxy-2-(4-methoxy-3,5-dimethyl-2-pyridinyl) methylsulfinyl)-1H-benzimidazole (omeprazole).
  • Determination of omeprazole in pharmaceuticals by derivative spectroscopy.
  • Prolonged and profound acid inhibition is crucial in Helicobacter pylori treatment with a proton pump inhibitor combined with amoxicillin.
  • CYP3A4 is the major CYP isoform mediating the in vitro hydroxylation and demethylation of flunitrazepam.
  • Difference between two isozymes of (Na+ + K+)-ATPase in the interaction with omeprazole.
  • Ouabain-insensitive K-adenosine triphosphatase in distal nephron segments of the rabbit.
  • Prospective study of erradication of Helicobacter pylori in patients with duodenal ulcer: analysis of antral and gastric body biopsies
  • Inhibition of gastric K+/H+-ATPase by acid-activated 2-((2-pyridylmethyl)sulphinyl)benzimidazole products.
  • Inhibition of gastric (H+ + K+)-ATPase by the substituted benzimidazole, picoprazole.
  • Oxidative metabolism of lansoprazole by human liver cytochromes P450.
  • The pharmacodynamics of lansoprazole administered via gastrostomy as intact, non-encapsulated granules.
  • Inhibitory action of lansoprazole and its analogs against Helicobacter pylori: inhibition of growth is not related to inhibition of urease.
  • Determination of lansoprazole and its metabolites in plasma by high-performance liquid chromatography using a loop column.
  • Pharmacokinetics of lansoprazole in patients with renal or liver disease of varying severity.
  • Dose-response effect of lansoprazole in patients with Zollinger-Ellison syndrome
  • Diagnosis and therapy of laryngitis gastrica
  • Clinical evolution of laryngeal granulomas: treatment and prognosis.
  • Bouginage of peptic esophageal stenoses. Results of one year with long-term omeprazole medication
  • Course of histological lesions of the gastric mucosa after eradication of H. pylori in patients with duodenal ulcer. Initial study and 6-month follow-up
  • A simple high performance liquid chromatography assay for simultaneous determination of omeprazole and metronidazole in human plasma and gastric fluid.
  • Potential hazards of long-term acid suppression.
  • Temporary cessation of long-term maintenance treatment with omeprazole in patients with H2-receptor-antagonist-resistant reflux oesophagitis. Effects on symptoms, endoscopy, serum gastrin, and gastric acid output.
  • Serum gastrin levels during long-term omeprazole treatment.
  • Antibacterial properties of lansoprazole alone and in combination with antimicrobial agents against Helicobacter pylori.
  • Treatment of gastric MALT lymphoma by Helicobacter pylori eradication: a study controlled by endoscopic ultrasonography.
  • Synergic interactions of macrolides and proton-pump inhibitors against Helicobacter pylori: a comparative in-vitro study.
  • Bile reflux in benign and malignant Barrett's esophagus: effect of medical acid suppression and nissen fundoplication.
  • Proton pump inhibitor for maintenance therapy of peptic ulcer
  • Treatment of Barrett esophagus with argon plasma coagulation with acid suppression--a prospective study
  • Effects of H2-receptor antagonists upon physiological acid secretory states in animals.
  • Histamine H2-receptor mediated stimulation of gastric acid secretion by mercaptomethylimidazole.
  • Ticlopidine as a selective mechanism-based inhibitor of human cytochrome P450 2C19.
  • Economic evaluation of new medical technology.
  • Pharmacokinetics and metabolism of omeprazole in man.
  • Phenocopies of poor metabolizers of omeprazole caused by liver disease and drug treatment.
  • Lansoprazole and ethanol metabolism: comparison with omeprazole and cimetidine.
  • Evaluation of combined antibiotic-omeprazole therapies in Helicobacter pylori-infected Mongolian gerbils.
  • Omeprazole and dry mouth.
  • Antiulcer drugs and gastric mucosal integrity. Effects of misoprostol, 16,16-dimethyl PGE2, and cimetidine on hemodynamics and metabolic rate in canine gastric mucosa.
  • Adenocarcinoma of the rat esophagus in the presence of a proton pump inhibitor: a pilot study.
  • Targeting the fungal plasma membrane proton pump.
  • Restoration of squamous mucosa after ablation of Barrett's esophageal epithelium.
  • Co-purification of gastric mucoproteins with DNA: an explanation for the reported 'interaction' of omeprazole with DNA in rat tissues.
  • Influence of anti-Helicobacter triple-therapy with metronidazole, omeprazole and clarithromycin on intestinal microflora.
  • Cytoprotective effect of NC-1300-O-3 against gastric lesions induced by necrotizing agents in rats.
  • Conformational analysis: a new approach by means of chemometrics.
  • Omeprazole and dietary nitrate independently affect levels of vitamin C and nitrite in gastric juice.
  • Bacterial formation of N-nitroso compounds in the rat stomach after omeprazole-induced achlorhydria.
  • Omeprazole inhibits nocturnal and pentagastrin-stimulated gastric secretion in man.
  • Previous use of non-steroidal anti-inflammatory drugs and anticoagulants: the influence on clinical outcome of bleeding gastroduodenal ulcers.
  • Does concurrent acute ethanol ingestion during omeprazole therapy affect pituitary gonadal axis in male subjects?
  • Carbonic anhydrase in the normal rat stomach and duodenum and after treatment with omeprazole and ranitidine.
  • Lack of gastric toxicity of nitric oxide-releasing aspirin, NCX-4016, in the stomach of diabetic rats.
  • Optimizing the information obtained from continuous 24-hour gastric pH monitoring.
  • Nonsteroidal anti-inflammatory drug and phospholipid prodrugs: combination therapy with antisecretory agents in rats.
  • Prolonged remission of oesophagitis does not alter the magnitude of oesophageal acid exposure.
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  • Endoscopic characteristics of low-grade gastric mucosa-associated lymphoid tissue lymphoma after eradication of Helicobacter pylori.
  • Pharmacokinetic comparison of omeprazole capsules and a simplified omeprazole suspension.
  • Discovery and development of the proton pump inhibitor
  • Effects of the enantiomers of lansoprazole (AG-1749) on (H+ + K+)-ATPase activity in canine gastric microsomes and acid formation in isolated canine parietal cells.
  • Effects of omeprazole on ethanol metabolism: an in vitro and in vivo rat and human study.
  • Omeprazole inhibits growth of cancer cell line of colonic origin.
  • B-cell lymphoma (MALToma) of the stomach and Helicobacter pylori infection
  • Identification of the site of inhibition by omeprazole of a alpha-beta fusion protein of the H,K-ATPase using site-directed mutagenesis.
  • Effects of cimetidine and omeprazole on angiogenesis in granulation tissue of acetic acid-induced gastric ulcers in rats.
  • Studies on the effects of omeprazole on thyroid function in the rat.
  • Effects of leminoprazole, omeprazole and sucralfate on indomethacin-induced delayed healing of kissing gastric ulcers in rats.
  • The effect of ammonia on omeprazole-induced reduction of gastric acidity in subjects with Helicobacter pylori infection.
  • Effect of cimetidine and omeprazole on aspirin- and taurocholate-induced gastric mucosal damage in the rat.
  • First-pass metabolism of omeprazole in rats.
  • One-week treatment with omeprazole, clarithromycin and amoxicillin: high efficacy in the eradication of Helicobacter pylori and cicatrization of duodenal ulcer
  • Clinico-pharmacological evaluation of omeprazole, as a proton pump inhibitor, compared with H2-blockers
  • Inhibition of 14C-aminopyrine accumulation in isolated rabbit gastric glands by the H2-receptor antagonist HOE 760 (TZU-0460).
  • Mechanism of action of omeprazole.
  • Effect of enprostil on omeprazole-induced hypergastrinemia and inhibition of gastric acid secretion in peptic ulcer patients.
  • The effect of omeprazole-induced hypergastrinemia on the oxyntic mucosa of mastomys.
  • Relationship of omeprazole-induced hypergastrinemia to gastric pH.
  • Modified combined omeprazole/amoxicillin therapy for Helicobacter pylori eradication: a pilot study
  • Comparison of the antisecretory effects of omeprazole when administered intravenously, as acid-stable granules and as an oral paste in horses.
  • The specificity of omeprazole as an (H+ + K+)-ATPase inhibitor depends upon the means of its activation.
  • Differences in the antisecretory actions of the proton pump inhibitor AG-1749 (lansoprazole) and the histamine H2-receptor antagonist famotidine in rats and dogs.
  • Effect of long-term omeprazole treatment on antral G and D cells in children.
  • Effect of high dose omeprazole on gastric pepsin secretion and serum pepsinogen levels in man.
  • Catalysis of oxygen-18 exchange between inorganic phosphate and water by the gastric H,K-ATPase.
  • Prolonged effect of omeprazole on the 14C-urea breath test.
  • An acid-independent antiulcer effect of M1 antimuscarinics in the rat.
  • The efficacy of the omeprazole-levosulpiride combination in the therapy of distal reflux esophagitis
  • Effect of short-term omeprazole administration on serum pepsinogens in relation to fasting serum gastrin and gastric acid secretion.
  • Effects of NaSCN and omeprazole on resistance and potential of fundus of Rana pipiens.
  • Optimal dose of oral omeprazole for maximal 24 hour decrease of intragastric acidity.
  • In vitro studies on omeprazole metabolism in rat liver microsomes
  • Rectal absorption of omeprazole from suppository in humans.
  • The hydroxylation of omeprazole correlates with S-mephenytoin and proguanil metabolism.
  • Relaxation induced by omeprazole does not change in diabetic rabbit corpus cavernosum.
  • Identification and expression of prohormone-converting enzymes in the rat stomach.
  • Omeprazole in H2 receptor antagonist-resistant reflux esophagitis.
  • Inhibition of iron absorption by omeprazole in rat model.
  • Oral bioavailability of omeprazole before and after chronic therapy in patients with duodenal ulcer.
  • Maintenance therapy with antiulcer drugs: review of 71 cases
  • Extent and variation of omeprazole prescribing in an elderly population of Ontario.
  • One-week treatment with omeprazole, clarithromycin, and metronidazole in children with Helicobacter pylori infection.
  • Comparison of IY81149 with omeprazole in rat reflux oesophagitis.
  • Effects of misoprostol and omeprazole on basal gastric pH and free acid content in horses.
  • Animal pharmacodynamics of omeprazole. A survey of its pharmacological properties in vivo.
  • Empiric trial of high-dose omeprazole in patients with posterior laryngitis: a prospective study.
  • Effects of antimuscarinic agents, H2-blockers and omeprazole on rat chronic gastric ulcer after long- and short-term administration.
  • The effects of rabeprazole on parietal cells and enterochromaffin-like cells in rats: a comparison with omeprazole.
  • Cytological transformations associated with parietal cell stimulation: critical steps in the activation cascade.
  • Gastrin-mediated effects of omeprazole on rat colon mucosa.
  • Effects of acid suppression and bismuth medications on the performance of diagnostic tests for Helicobacter pylori infection.
  • Continued (5-year) followup of a randomized clinical study comparing antireflux surgery and omeprazole in gastroesophageal reflux disease.
  • AHR-9294: a novel inhibitor of H,K-ATPase antagonizes gastric HCl secretion in vivo.
  • Short report: the effect of omeprazole on Helicobacter pylori and associated gastritis.
  • Repeated high oral doses of omeprazole do not affect intrinsic factor secretion: proof of a selective mode of action.
  • Omeprazole in the treatment of Zollinger-Ellison syndrome: a 4-year international study.
  • Pharmacology and toxicology of omeprazole--with special reference to the effects on the gastric mucosa.
  • Effects of omeprazole and famotidine on (H+-K+) ATPase and acid secretion in rabbit gastric glands
  • Microelectrode measurements of K+ and pH in rabbit gastric glands: effect of histamine.
  • Mechanisms of protection by omeprazole against experimental gastric mucosal damage in rats.
  • Different biochemical modes of action of two irreversible H+,K(+)-ATPase inhibitors, omeprazole and E3810.
  • Influence of bafilomycin A1 on pHi responses in cultured rabbit nonpigmented ciliary epithelium.
  • Antisecretory effect and oral pharmacokinetics following low dose omeprazole in man.
  • Effect of intravenous and oral omeprazole on 24-hour intragastric acidity in duodenal ulcer patients.
  • Detection of ouabain-insensitive H(+)-transporting, K(+)-stimulated p-nitrophenylphosphatase activity in rat gastric glands by cerium-based cytochemistry.
  • Omeprazole inhibits oxidative drug metabolism. Studies with diazepam and phenytoin in vivo and 7-ethoxycoumarin in vitro.
  • Omeprazole: effects on oxidative drug metabolism.
  • Cimetidine and omeprazole accelerate gastric ulcer healing by an increase in gastrin secretion.
  • Effect of omeprazole and feeding on plasma gastrin in patients with achlorhydria.
  • Somatostatin cells in the oxyntic mucosa of hypo- or hypergastrinemic rats.
  • Assessment of cytochrome P450 activity by a five-drug cocktail approach.
  • Feedback control of pancreatic secretion in rats. Role of gastric acid secretion.
  • Chiral resolution of pantoprazole sodium and related sulfoxides by complex formation with bovine serum albumin in capillary electrophoresis.
  • Function and structure of parietal cells after H+-K+-ATPase blockade.
  • Helicobacter pylori in patients with systemic sclerosis: detection with the 13C-urea breath test and eradication.
  • Respiratory symptoms in patients with gastroesophageal reflux disease following medical therapy and following antireflux surgery.
  • Characterization of peanut-lectin (+) cells derived from the RCCT-28A cell line.
  • The effect of pentadecapeptide BPC 157, H2-blockers, omeprazole and sucralfate on new vessels and new granulation tissue formation.
  • Effect of inhibition of pentagastrin-stimulated acid secretion on gastric mucosal gland luminal pressure.
  • Antiulcerogenicity of the flavonoid fraction from Bidens aurea: comparison with ranitidine and omeprazole.
  • Diagnostic value of serum pepsinogen C in patients with raised serum concentrations of pepsinogen A.
  • Nonparallel secretion of pepsinogen and acid by gastric oxyntopeptic cells of the toad (Bufo marinus).
  • Omeprazole increases permeability across isolated rat gastric mucosa pre-treated with an acid secretagogue.
  • Pharmacokinetic-pharmacodynamic study of oral lansoprazole in children.
  • Comparative pharmacokinetic/pharmacodynamic analysis of proton pump inhibitors omeprazole, lansoprazole and pantoprazole, in humans.
  • Lansoprazole pharmacokinetics in subjects with various degrees of kidney function.
  • Biochemical and pharmacological properties of a newly synthesized proton pump (H+/K(+)-ATPase) inhibitor, TY-11345 in experimental animals.
  • Biochemical and pharmacological properties of a new proton pump inhibitor, 2-amino-4,5-dihydropyrido1,2-athiazolo 5,4-g benzimidazole (YJA20379-5).
  • CYP2C19 genotype and phenotype determined with omeprazole in patients with acid-related disorders with and without Helicobacter pylori infection.
  • Effects of lansoprazole on pharmacokinetics and metabolism of theophylline.
  • Gastric mucosal function following withdrawal of omeprazole in rats.
  • Inhibition of the plasma-membrane H(+)-ATPase from Dunaliella adidophila by omeprazole.
  • Effects of arachidonic acid, prostaglandins, retinol, retinoic acid and cholecalciferol on xenobiotic oxidations catalysed by human cytochrome P450 enzymes.
  • Effect of clarithromycin and other macrolides on the sulfoxidation and 5-hydroxylation of lansoprazole in dogs.
  • Signal transduction-mediated CYP1A1 induction by omeprazole in human HepG2 cells.
  • Analysis of indications and diagnosis of the gastroscopies requested by primary care physicians
  • Inhibition of transketolase and pyruvate decarboxylase by omeprazole.
  • Studies on the mechanism of action of A80915A, a semi-naphthoquinone natural product, as an inhibitor of gastric (H(+)-K+)-ATPase.
  • Analysis of gastrin receptor gene expression in proliferating cells in the neck zone of gastric fundic glands using laser capture microdissection.
  • Effects of IY-81149, a newly developed proton pump inhibitor, on gastric acid secretion in vitro and in vivo.
  • Impact of a formulary change in proton pump inhibitors on health care costs and patients' symptoms.
  • Endoscopic topical therapy for the treatment of Helicobacter pylori infection.
  • Duodenal fat intensifies the perception of heartburn.
  • Hypergastrinemia in response to gastric inflammation suppresses somatostatin.
  • The effect of immobilization stress on the pharmacokinetics of omeprazole in rats.
  • Studies on the mechanism of action of the omeprazole-derived cyclic sulphenamide.
  • Wine stimulates gastric acid secretion in isolated rabbit gastric glands via two different pathways.
  • The gastric mucigenous function in the treatment of patients with ulcer with various antisecretory preparations
  • Nature of the gastric acid-gastrin feedback loop in the fetal sheep.
  • Prevalence of H. pylori-infection in family members of H. pylori positive and its influence on the reinfection rate after successful eradication therapy: a two-year follow-up.
  • Treatment of gastritis-associated Helicobacter pylori infection in children
  • Effect of omeprazole on oral and intravenous RS-methadone pharmacokinetics and pharmacodynamics in the rat.
  • Mechanism of gastric alkaline response in the stomach after damage. Roles of nitric oxide and prostaglandins.
  • Studies on the mechanism of action of the gastric microsomal (H+ + K+)-ATPase inhibitors SCH 32651 and SCH 28080.
  • Effect of various antisecretory drugs on morphological changes in rat gastric mucosa in experimental stomach ulcers
  • Effects of prostaglandin D2 and omeprazole on indomethacin-induced gastric ulcers in rats.
  • Antibiotic resistance of Helicobacter pylori in Reunion Island: therapeutic consequences
  • Determination of omeprazole and metabolites in plasma and urine.
  • Normalization of phospholipids concentration of the gastric mucosa was observed in patients with peptic ulcer after eradication of Helicobacter pylori.
  • Low efficacy of an ultra-short term, once-daily dose triple therapy with omeprazole, azithromycin, and secnidazole for Helicobacter pylori eradication in peptic ulcer.
  • Impact of proton pump inhibitor utilization patterns on gastroesophageal reflux disease-related costs.
  • Protective effect of omeprazole against acute gastric mucosal lesions induced by compound 48/80, a mast cell degranulator, in rats.
  • Effect of basolateral acidification on the frog oxynticopeptic cell.
  • Inhibition of cerebrospinal fluid formation by omeprazole.
  • Severity of esophageal eosinophilia predicts response to conventional gastroesophageal reflux therapy.
  • A cell-based reporter gene assay for determining induction of CYP3A4 in a high-volume system.
  • Submicroscopic aspects of the mechanism of inhibitors of H+/K+-ATPase in gastric parietal cells
  • Development and preliminary application of a high-performance liquid chromatographic assay for omeprazole metabolism in human liver microsomes.
  • Coordinated regulation of gastric chloride secretion with both acid and alkali secretion.
  • Prospective study on the incidence of chronic ear complaints related to gastroesophageal reflux and on the outcome of antireflux therapy.
  • Medium-term results of oral and intravenous omeprazole/amoxicillin Helicobacter pylori eradication therapy.
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  • Long-term curative effects of suture plus proximal gastric vagotomy or triad-therapy for duodenal ulcer with acute perforation
  • Omeprazole has no effect on acetaminophen kinetics in the rat.
  • Omeprazole, furazolidone, and tetracycline: an eradication treatment for resistant H. pylori in Brazilian patients with peptic ulcer disease.
  • Increased hepatocyte growth factor content in rat stomach during omeprazole treatment.
  • Persistent acid reflux and symptoms in patients with Barrett's oesophagus on proton-pump inhibitor therapy.
  • Microcirculation in gastric mucosa as related to its secretory activity in patients with peptic ulcer
  • Factors affecting ammonium uptake by C11 clone of MDCK cells.
  • Effect of nizatidine 300 mg at night and omeprazole 20 mg in the morning on 24-hour intragastric pH and bacterial overgrowth in patients with acute duodenal ulcer.
  • Modulation of the phototoxic effect of hypericin in human leukemia CEM cell line by N-ethylmaleimide, amiloride and omeprazole.
  • Effect of proton pump inhibitors on the continuous real time (13)C-urea breath test.
  • A novel antioxidant and antiapoptotic role of omeprazole to block gastric ulcer through scavenging of hydroxyl radical.
  • Hydrogen-potassium ATPase inhibitors induce relaxation on rabbit prostatic strips in vitro.
  • Anti-Helicobacter pylori therapy in India: differences in eradication efficiency associated with particular alleles of vacuolating cytotoxin (vacA) gene.
  • Monotherapy with mastic does not eradicate Helicobacter pylori infection from mice.
  • Esophageal clearance function following treatment of esophagitis.
  • In vitro study on capsule formulations of omeprazole containing enteric coated granules.
  • Differences in pH-dependent activation rates of substituted benzimidazoles and biological in vitro correlates.
  • Characterization of CYP2C19 and CYP2C9 from human liver: respective roles in microsomal tolbutamide, S-mephenytoin, and omeprazole hydroxylations.
  • Long-term follow-up of gastric metaplasia after eradication of Helicobacter pylori.
  • Gene expression of ornithine decarboxylase, cyclooxygenase-2, and gastrin in atrophic gastric mucosa infected with Helicobacter pylori before and after eradication therapy.
  • The state of immune system and effects of current therapy and immunomodulators
  • Evaluation of omeprazole as a cost-effective diagnostic test for gastro-oesophageal reflux disease.
  • The effect of commonly used drugs on angiogenesis.
  • Bioactivation of cyclophosphamide: the role of polymorphic CYP2C enzymes.
  • Type 2 diabetes mellitus affects eradication rate of Helicobacter pylori.
  • Effect of acid blockade on gastric histamine in mice.
  • Refinement of, and new applications for, Helicobacter pylori colonization in pig gastric biopsy specimens cultured in vitro.
  • Globus sensation and gastroesophageal reflux.
  • Nodular gastritis in adults is caused by Helicobacter pylori infection.
  • General practitioners' approach to dyspepsia. Survey of consultation frequencies, treatment, and investigations.
  • Antralization at the edge of proximal gastric ulcers: does Helicobacter pylori infection play a role?
  • The clinical role of cytochrome p450 genotypes in Helicobacter pylori management.
  • Gastric transitional zones, areas where Helicobacter treatment fails: results of a treatment trial using the Sydney strain mouse model.
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  • Synthesis of (aryloxy)alkylamines. 1. Novel antisecretory agents with H+K+-ATPase inhibitory activity.
  • Determination of omeprazole in bulk and injectable preparations by liquid chromatography.
  • Chloride transport of frog gastric fundus: effects of omeprazole.
  • Effectiveness of eradication anti-helicobacter therapy in patients with duodenal ulcer in different drug dosage regimens
  • Odds of moderate or severe gastric ulceration in racehorses receiving antiulcer medications.
  • Pharmacotherapy in complex treatment of ulcerous stenosis
  • Absence of an inhibitory effect of omeprazole and nizatidine on phenytoin disposition, a marker of CYP2C activity.
  • Impact of cotherapy with some proton pump inhibitors on medical claims among HMO patients already using other common drugs also cleared by cytochrome P450.
  • Polymorphic hydroxylation of S-mephenytoin and omeprazole metabolism in Caucasian and Chinese subjects.
  • Possible mechanisms for (H+ + K+)-ATPase inhibition by proton pump inhibitors, omeprazole, lansoprazole and SCH 28080
  • New fluorescent probes E3810 and methoxy E3810 for determining distributions of the apical membrane and the acidic compartment of gastric acid secreting cells.
  • Effects of omeprazole on the number of immunoreactive gastrin- and somatostatin-cells in the rat gastric mucosa.
  • Long-term persistence of resistant Enterococcus species after antibiotics to eradicate Helicobacter pylori.
  • Indomethacin damage to rat gastric mucosa is markedly dependent on luminal pH.
  • Relaxant effect of omeprazole and lansoprazole in guinea pig gallbladder muscle strips in vitro.
  • Four-day quadruple therapy as a routine treatment for Helicobacter pylori infection.
  • Sildenafil, a phosphodiesterase-5 inhibitor, delays gastric emptying and gastrointestinal transit of liquid in awake rats.
  • Divalent cations regulate acidity within the lumen and tubulovesicle compartment of gastric parietal cells.
  • Effect of a gastrin/cholecystokinin B receptor antagonist, S-0509, on the omeprazole-induced proliferation of gastric mucosa in rats.
  • Studies on the metabolism of omeprazole in the rat using liquid chromatography/ionspray mass spectrometry and the isotope cluster technique with 34Someprazole.
  • Study of protein assimilation, using stable isotope techniques.
  • 24-hour intragastric acidity and plasma gastrin during long-term treatment with omeprazole or ranitidine in patients with reflux esophagitis.
  • Histidine decarboxylase gene expression in rat fundus is regulated by gastrin.
  • Risk of gynaecomastia associated with cimetidine, omeprazole, and other antiulcer drugs.
  • Antibacterial effect of garlic and omeprazole on Helicobacter pylori.
  • Influence of Cl- on pH(i) in oxynticopeptic cells of in vitro frog gastric mucosa.
  • 24-hour intragastric acidity and plasma gastrin after omeprazole treatment and after proximal gastric vagotomy in duodenal ulcer patients.
  • Time course of inhibition of gastric acid secretion by omeprazole and ranitidine in gastric fistula rats.
  • Human gastric acid secretion following repeated doses of AG-1749.
  • Inhibition of acid secretion in guinea pigs by tricyclic antidepressants: comparison with ranitidine and omeprazole.
  • Influence of the stimulation state of the parietal cells on the inhibitory effect of omeprazole on gastric acid secretion in dogs.
  • Gastric ECL-cell hyperplasia and carcinoids in rodents following chronic administration of H2-antagonists SK&F 93479 and oxmetidine and omeprazole.
  • The mechanism for inhibition of gastric (H+ + K+)-ATPase by omeprazole.
  • Omeprazole: its influence on gastric acid secretion, gastrin and ECL cells.
  • Influence of prostaglandins, omeprazole, and indomethacin on healing of experimental gastric ulcers in the rat.
  • Effect of indomethacin on gastric mucosal blood flow around acetic acid-induced gastric ulcers in rats.
  • Modelling of colonic Cl- and K+ transport under resting and secreting conditions.
  • Effect of oral omeprazole on serum gastrin and serum pepsinogen I levels.
  • Gastroprotective activity of the novel proton pump inhibitor lansoprazole in the rat.
  • Iron-deficiency anemia associated with Helicobacter pylori gastritis.
  • Healing and relapse rates of duodenal ulcer with omeprazole vs ranitidine.
  • Chronic cough and hoarseness in patients with severe gastroesophageal reflux disease. Diagnosis and response to therapy.
  • Baclofen therapy for chronic hiccup.
  • The omeprazole treatment of patients with diseases of the upper digestive tract
  • Highly significant change of the clinical course of relapsing and complicated peptic ulcer disease after cure of Helicobacter pylori infection.
  • Differential effects of Na+, K(+)-ATPase inhibition by ouabain on acid secretory responses to histamine and bethanechol in the mouse isolated stomach.
  • Synthesis of 2-(4-fluoroalkoxy-2-pyridyl)methylsulfinyl-1H- benzimidazoles as antiulcer agents.
  • Endoscopic ultrasonographic (EUS) evaluation of the quality of gastric ulcer healing.
  • Regression of columnar lined (Barrett's) oesophagus with continuous omeprazole therapy.
  • Long-term omeprazole therapy does not affect Helicobacter pylori status in most patients.
  • The effect of omeprazole on healing of duodenal ulcers, Helicobacter pylori and gastritis
  • Long-term omeprazole therapy in peptic ulcer disease: gastrin, endocrine cell growth, and gastritis.
  • Induction of cytochrome P450 3A (CYP 3A) by E 5110, a non-steroidal anti-inflammatory agent (NSAID), and typical CYP 3A inducers in primary cultures of dog hepatocytes.
  • Reversible inhibition of rat gastric H+/K+-ATPase by T-330, 2-2-dimethylaminobenzyl)sulfinyl-1-(3-methylpyridine-2-yl)imidazole.
  • One-week triple therapy with omeprazole, amoxycillin and either clarithromycin or metronidazole for cure of Helicobacter pylori infection.
  • Mechanisms behind changes in gastric acid and bicarbonate outputs during the human interdigestive motility cycle.
  • The chemotherapeutic effects of H+/K+ inhibitors on Helicobacter pylori infection.
  • Effects of inhibition of gastric secretion on antral gastrin and somatostatin gene expression in rats.
  • Omeprazole produces parietal cell hypertrophy and hyperplasia in humans.
  • Duodenogastric reflux causes growth stimulation of foregut mucosa potentiated by gastric acid blockade.
  • Studies on the interrelation between Zollinger-Ellison syndrome, Helicobacter pylori, and proton pump inhibitor therapy.
  • Omeprazole potentiates atracurium and succinylcholine paralysis in vivo in rats.
  • Prevention of recurrences of erosive reflux esophagitis: a cost-effectiveness analysis of maintenance proton pump inhibition.
  • Gastric acid secretion is augmented by the replacement of extracellular Na+ with K+ or other ions.
  • Effectiveness of short-term triple therapy for healing Helicobacter pylori infection in ulcer disease
  • Signal transduction-mediated activation of the aryl hydrocarbon receptor in rat hepatoma H4IIE cells.
  • Oral SIV, SHIV, and HIV type 1 infection.
  • Appearance of myofibroblasts in the gastric mucosa after ingestion of ethanol and lansoprazole with reevaluation of the mucoid cap.
  • Effects of omeprazole on gastric mucosal blood flow in the conscious rat.
  • Protection of gastric epithelial cell monolayers from a human cell line by omeprazole in vitro.
  • Interference on Helicobacter pylori growth and adhesion by omeprazole and other drugs.
  • Mesalazine release from a pH dependent formulation: effects of omeprazole and lactulose co-administration.
  • Different acid secretagogues activate different Na+/H+ exchanger isoforms in rabbit parietal cells.
  • Rebound hypersecretion after omeprazole and its relation to on-treatment acid suppression and Helicobacter pylori status.
  • Effect of CYP2C19 polymorphism on serum levels of vitamin B12 in patients on long-term omeprazole treatment.
  • Effect of omeprazole and polyethylene glycol-400 on antipyrine elimination by the isolated perfused rat liver.
  • Wrong-way swallowing as a possible cause of bronchitis in patients with gastroesophageal reflux disease.
  • Photodynamic therapy in Barrett's esophagus: reduction of specialized mucosa, ablation of dysplasia, and treatment of superficial esophageal cancer.
  • Clinical efficacy of proton pump inhibitor therapy in neurologically impaired children with gastroesophageal reflux: prospective study.
  • Very early detection of RET proto-oncogene mutation is crucial for preventive thyroidectomy in multiple endocrine neoplasia type 2 children: presence of C-cell malignant disease in asymptomatic carriers.
  • Effects of omeprazole on gastric mucosal growth and differentiation in developing rat.
  • Characteristic features of proton pump inhibitors in the inhibition of gastric acid secretion: long-acting and complete inhibition
  • High doses of ranitidine in patients with reflux oesophagitis.
  • Ultrastructure of inhibited parietal cells in the rat.
  • Eradication of Helicobacter pylori with clarithromycin and omeprazole.
  • Identification of the human P450 enzymes involved in lansoprazole metabolism.
  • Eradication of helicobacter pylori among patients from a primary care practice.
  • Inhibition by omeprazole of proguanil metabolism: mechanism of the interaction in vitro and prediction of in vivo results from the in vitro experiments.
  • Why are patients prescribed proton pump inhibitors? Retrospective analysis of link between morbidity and prescribing in the General Practice Research Database.
  • Influencing prescribing practices and associated outcomes utilizing the drug use evaluation process.
  • Use of omeprazole for premedication
  • Effects of YJA20379-4 on gastric secretion, Helicobacter pylori growth and various gastric and duodenal lesions in rats.
  • Use of a five-day test to predict the long-term effects of gastric antisecretory agents on serum gastrin in rats.
  • The effect of omeprazole pretreatment on acetaminophen metabolism in rapid and slow metabolizers of S-mephenytoin.
  • Na+/H+ antiporter is the primary proton transport system used by osteoclasts during bone resorption.
  • Comparative tolerability profile of omeprazole in clinical trials.
  • Genotoxicity and cell proliferative activity of omeprazole in rat stomach mucosa.
  • Involvement of heat shock proteins in the healing of acetic acid-induced gastric ulcers in rats.
  • Lansoprazole, a novel benzimidazole proton pump inhibitor, and its related compounds have selective activity against Helicobacter pylori.
  • Effect of substituted benzimidazoles on acid secretion in isolated and enriched guinea pig parietal cells.
  • Prevalence of potential proton-pump inhibitor drug interactions: a retrospective review of prescriptions in community pharmacies.
  • Omeprazole-induced pseudohypertrophy of gastric parietal cells.
  • Regression of primary gastric lymphoma of mucosa-associated lymphoid tissue type after cure of Helicobacter pylori infection. MALT Lymphoma Study Group.
  • Current or recent proton pump inhibitor therapy markedly impairs the accuracy of the 14Curea breath test.
  • Omeprazole, Helicobacter pylori status, and alterations in the intragastric milieu facilitating bacterial N-nitrosation.
  • Second-line Helicobacter pylori eradication with a furazolidone-based regimen in patients who have failed a metronidazole-based regimen.
  • Gastrin cell responses to acidification of the achlorhydric rat stomach.
  • Impact of Helicobacter pylori and Giardia lamblia infections on chronic urticaria.
  • Effect of Helicobacter pylori eradication on gastritis in relation to cagA: a prospective 1-year follow-up study.
  • Effect of Helicobacter pylori eradication on gastric histology, serum gastrin and pepsinogen I levels, and gastric emptying in patients with gastric ulcer.
  • Effect of Helicobacter pylori on gastric epithelial apoptosis
  • Treatment of Helicobacter pylori infection in clinical practice in the United States: results from 224 patients.
  • Influence of Helicobacter pylori infection on healing and relapse of acetic acid ulcers in Mongolian gerbils.
  • The role of endogenous gastrin in the development of enterochromaffin-like cell carcinoid tumors in Mastomys natalensis: a study with the specific gastrin receptor antagonist AG-041R.
  • Rx drugs
  • Effect of omeprazole on H. pylori after two weeks of treatment.
  • Molecular modelling and quantitative structure-activity relationship studies on the interaction of omeprazole with cytochrome P450 isozymes.
  • Effect of cimetidine, ranitidine, famotidine and omeprazole on hepatocyte proliferation in vitro.
  • Effects of omeprazole and ranitidine on gastric acid secretion, blood gastrin levels and 3H-thymidine incorporation in the oxyntic mucosa from dogs and rats.
  • A study on the relation between proton pump inhibitor and gastric giardiasis.
  • Gastroduodenal ulcers in rats induced by 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP): requirement for gastric acid secretion and the role of prostaglandins.
  • Protease-activated receptor-2 (PAR-2) in the rat gastric mucosa: immunolocalization and facilitation of pepsin/pepsinogen secretion.
  • H+ transport by reconstituted gastric (H+ + K+)-ATPase.
  • H2-receptor antagonist reduces food intake and weight gain in rats by non-gastric acid secretory mechanisms.
  • Regression of duodenal gastric metaplasia in Helicobacter pylori positive patients with duodenal ulcer disease.
  • Stimulation of gastric bicarbonate secretion by an analog of thyrotropin-releasing hormone, YM-14673, in the rat.
  • Increased acid and bile reflux in Barrett's esophagus compared to reflux esophagitis, and effect of proton pump inhibitor therapy.
  • Evidence for a common binding site for omeprazole and N-ethylmaleimide in subunit A of chromaffin granule vacuolar-type H(+)-ATPase.
  • Effect of omeprazole on regional and temporal variations in intragastric acidity.
  • Helicobacter pylori reinfection is rare in peptic ulcer patients cured by antimicrobial therapy.
  • Helicobacter pylori of remnant stomach and optimal dose of amoxicillin for eradicating Helicobacter pylori.
  • Effect of single and repeated intravenous doses of omeprazole on pentagastrin stimulated gastric acid secretion and pharmacokinetics in man.
  • Helicobacter pylori of the remnant stomach and its eradication.
  • Morphometric assessment of reflux oesophagitis in fibreoptic biopsy specimens.
  • Secretory and biosynthetic responses of gastrin and somatostatin to acute changes in gastric acidity.
  • Omeprazole, a specific gastric secretion inhibitor on oxynticopeptic cells, reduces gizzard erosion in broiler chicks fed with toxic fish meals.
  • Impact of clarithromycin resistance on the effectiveness of a regimen for Helicobacter pylori: a prospective study of 1-week lansoprazole, amoxycillin and clarithromycin in active peptic ulcer.
  • Acquisition of secondary resistance after failure of a first treatment of Helicobacter pylori infection in children
  • Omeprazole induces altered bile acid metabolism.
  • The liver regenerative response elicited by antisecretory agents in partially hepatectomized rats: a comparison between omeprazole and famotidine.
  • Antacid provides better restoration of glandular structures within the gastric ulcer scar than omeprazole.
  • Biomarker studies in reversed Barrett's esophagus.
  • Gastrin effects on isolated rat enterochromaffin-like cells following long-term hypergastrinaemia in vivo.
  • Presumed laryngo-pharyngeal reflux: investigate or treat?
  • Thioredoxin and thioredoxin reductase show function-related changes in the gastric mucosa: immunohistochemical evidence.
  • Long-term consequences with regard to clinical outcome and cost-effectiveness of episodic treatment with omeprazole or ranitidine for healing of duodenal ulcer.
  • Modern diagnosis of gastroesophageal reflux disease (GERD).
  • Long-term efficacy and safety of omeprazole in patients with Zollinger-Ellison syndrome: a prospective study.
  • Movement of gastric acid secretion and influence of proton pump inhibitors on histamine H2 receptor antagonist resistant ulcer
  • The regulation of gastrin secretion in the chicken.
  • Inhibitions of acid secretion by E3810 and omeprazole, and their reversal by glutathione.
  • Suppression of acid secretion and plasma level of a once-daily dose of omeprazole
  • Effects of anti-acid secretory agents on various types of gastric mucus.
  • Hypergastrinemia after blockade of acid secretion in the rat: trophic effects.
  • Metabolic interactions of selected antimalarial and non-antimalarial drugs with the major pathway (3-hydroxylation) of quinine in human liver microsomes.
  • Relevance of antibiotic sensitivities in predicting failure of omeprazole, clarithromycin, and tinidazole to eradicate Helicobacter pylori.
  • Inter-relationship between serum gastrin levels, gastric mucosal histology and gastric endocrine cell growth.
  • The influence of gastrointestinal agents on resorption and metabolism of cyclosporine after heart transplantation: experimental and clinical results.
  • Inhibition of gastric acid secretion by omeprazole and ranitidine. Effects on plasma gastrin and gastric histamine, histidine decarboxylase activity and ECL cell density in normal and antrectomized rats.
  • Inhibition of gastric acid secretion in vivo and in vitro by an inhibitor of Cl(-)-HCO3- exchanger, 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid.
  • Gastric H+-K+-ATPase in situ: relation to secretory state.
  • Mechanism for species-specific induction of Leydig cell tumors in rats by lansoprazole.
  • Effects of CCK2 receptor blockade on growth parameters in gastrointestinal tract and pancreas in rats.
  • CagA seropositivity and the severity of Helicobacter pylori infection in dyspeptic children.
  • Pharmacokinetics of various single intravenous and oral doses of omeprazole.
  • Endoscopic assessment of blood flow in duodenal ulcers.
  • Active immunization against somatostatin alters regulation of gastrin in response to gastric acid secretagogues.
  • Mechanism of cholinergic stimulation of glucose oxidation in isolated gastric glands.
  • Making sense of NSAID gastropathy and considering the therapeutic options.
  • Endogenous gastrin stimulates regeneration of remnant pancreas after partial pancreatectomy.
  • Mucosal change of the stomach with low-grade mucosa-associated lymphoid tissue lymphoma after eradication of Helicobacter pylori: follow-up study of 48 cases.
  • Gastric mucosal histamine storing cells. Evidence for different roles of mast cells and enterochromaffin-like cells in humans.
  • Effect of high ionic strength and inhibitors of H,K-ATPase on the ouabain-sensitive K-p-nitrophenylphosphatase activity in the sea anemone Stichodactyla helianthus.
  • The cost-effectiveness of strategies to assess gastroesophageal reflux as an exacerbating factor in asthma.
  • The usefulness of a structured questionnaire in the assessment of symptomatic gastroesophageal reflux disease.
  • Proton pump inhibitors: a study of GPs' prescribing.
  • Effects of omeprazole, a substituted benzimidazole, on gastrointestinal secretions, serum gastrin, and gastric mucosal blood flow in dogs.
  • Omeprazole: inhibitor of both acid formation and translocation in gastric mucosa.
  • Jejunal efflux in short bowel syndrome.
  • Evaluation of the gastroprotective activity of cordatin, a diterpene isolated from Aparisthmium cordatum (Euphorbiaceae).
  • Mobilization of rat stomach ECL-cell histamine in response to short- or long-term treatment with omeprazole and/or YF 476 studied by gastric submucosal microdialysis in conscious rats.
  • Sucralfate affects the susceptibility of Helicobacter pylori to antimicrobial agents.
  • Outcomes of atypical symptoms attributed to gastroesophageal reflux treated by laparoscopic fundoplication.
  • Exploring an antifungal target in the plasma membrane H(+)-ATPase of fungi.
  • Evaluation of a proposed technique to assess unscheduled DNA synthesis and genotoxicity.
  • Reversal by omeprazole of the depression of gastrin cell function by fasting in the rat.
  • The secretory kinetics of the G cell in omeprazole-treated rats.
  • Omeprazole fails to alter the cytochrome P450-dependent 2-hydroxylation of estradiol in male volunteers.
  • Metabolic interactions of the proton-pump inhibitors lansoprazole, omeprazole and pantoprazole with other drugs.
  • Pharmacokinetic differences between lansoprazole enantiomers and contribution of cytochrome P450 isoforms to enantioselective metabolism of lansoprazole in dogs.
  • Omeprazole maintenance therapy for gastroesophageal reflux disease after failure of fundoplication.
  • Regression of low-grade gastric mucosa-associated lymphoid tissue lymphoma after eradication of Helicobacter pylori: possible association with p16 hypermethylation.
  • Short-term eradication therapy for Helicobacter pylori does not reduce the incidence of gastric metaplasia in duodenal ulcer patients.
  • Proton pump inhibitor therapy: preliminary results of a therapeutic interchange program.
  • Effects of NC-1300-B, a new benzimidazole derivative, on hog gastric H+, K+-ATPase, gastric acid secretion and HCl.ethanol-induced gastric lesions in rats.
  • Substituted thieno3,4-dimidazoles, a novel group of H+/K(+)-ATPase inhibitors. Differentiation of their inhibition characteristics from those of omeprazole.
  • A comparative study on the activity of lansoprazole, omeprazole and PD-136450 on acidified ethanol- and indomethacin-induced gastric lesions in the rat.
  • The role of omeprazole in the eradication of Helicobacter pylori in patients with duodenal ulcers
  • Proton pump inhibitors in the treatment of peptic ulcers resistant to H2-receptor antagonists
  • Enzyme kinetic studies on the in vitro metabolism of omeprazole by Chinese human liver microsomes
  • The role of thyrotropin-releasing hormone (TRH) in the pathogenesis of water-immersion stress in rats--inhibition of TRH release from the stomach by atropine, ranitidine or omeprazole.
  • Omeprazole may exert both a bacteriostatic and a bacteriocidal effect on the growth of Helicobacter pylori (NCTC 11637) in vitro by inhibiting bacterial urease activity.
  • Influences of stress on gastric alkaline secretion in rats.
  • Chemomechanical coupling in the gastric H,K ATPase.
  • Pharmacokinetic differences between lansoprazole enantiomers in rats.
  • Omeprazole does not enhance the metabolism of phenacetin, a marker of CYP1A2 activity, in healthy volunteers.
  • Effect of omeprazole in the treatment of refractory acid-related diseases in childhood: endoscopic healing and twenty-four-hour intragastric acidity.
  • Evidence for acid-induced transformation of omeprazole into an active inhibitor of (H+ + K+)-ATPase within the parietal cell.
  • Long-term omeprazole treatment suppresses body weight gain and bone mineralization in young male rats.
  • Effect of omeprazole treatment on feed intake and blood gastrin and pepsinogen levels in the calf.
  • One-day therapy for treatment of Helicobacter pylori infection.
  • Cost-effectiveness of treatment regimens for the eradication of Helicobacter pylori in duodenal ulcer.
  • Factors that may affect treatment outcome of triple Helicobacter pylori eradication therapy with omeprazole, amoxicillin, and clarithromycin.
  • Effect of omeprazole on gastroesophageal reflux in Barrett's esophagus.
  • Clarithromycin resistance, but not CYP2C-19 polymorphism, has a major impact on treatment success in 7-day treatment regimen for cure of H. pylori infection: a multiple logistic regression analysis.
  • The use of Smecta for the treatment of the basic digestive tract diseases
  • Study on omeprazole 20 mg twice weekly in prevention of duodenal ulcer relapse
  • Omeprazole in peptic ulceration: acid inhibition and endoscopic healing
  • Insulin-induced gastric ulcers in the rat.
  • Comparative evaluation of ulcer prevention efficacy of orally, rectally and sublingually administered omeprazole in three acute gastric ulcer models in rats.
  • Inhibition of H+,K+-ATPase by methyl(E)-2-(3,4-dimethoxystyryl)-benzimidazole-4-carboxylate (ALE-36).
  • Proton pump inhibition--the ultimate control of acid secretion?
  • The effect of omeprazole on ultrastructural changes in gastric parietal cells.
  • Secondary prevention of upper gastrointestinal bleeding associated with maintenance acid-suppressing treatment in patients with peptic ulcer bleed.
  • Effect of omeprazole on gastric acid secretion in man.
  • Identification of two main urinary metabolites of 14Comeprazole in humans.
  • Association of chronic urticaria with Helicobacter pylori-induced antrum gastritis
  • Current principles of the use of laparoscopic surgery in gastroduodenal ulcer
  • Effect of L-lactic acid on calcium absorption in rats fed omeprazole.
  • Effect of intermittent weekend therapy with omeprazole on basal and postprandial serum gastrin concentrations in patients with duodenal ulcer.
  • Response of MBT-2 bladder carcinoma-induced osteolysis to various agents.
  • pH monitoring in patients with benign voice disorders.
  • Visual disorders associated with omeprazole and their relation to CYP2C19 polymorphism.
  • Effect of 'weekend therapy' with omeprazole on basal and stimulated acid secretion and fasting plasma gastrin in duodenal ulcer patients.
  • Symptomatic benefit 1-3 years after H. pylori eradication in ulcer patients: impact of gastroesophageal reflux disease.
  • Effect of omeprazole--a gastric proton pump inhibitor--on pentagastrin stimulated acid secretion in man.
  • Gastrin receptor antagonist YM022 prevents hypersecretion after long-term acid suppression.
  • Omeprazole in the Zollinger-Ellison syndrome.
  • The cultured human gastric cells HGT-1 express the principal transporters involved in acid secretion.
  • Properties of a potassium channel in cultured human gastric cells (HGT-1) possessing specific omeprazole binding sites.
  • Effect of sham feeding and acute suppression of acid secretion on human gastric lipase secretion.
  • Omeprazole treatment of children with peptic esophagitis refractory to ranitidine therapy.
  • Comparison between activation of ornithine decarboxylase and histidine decarboxylase in rat stomach.
  • Evaluation of chromo-endoscopy for diagnosis of histological repair of gastric ulcer
  • High-performance liquid chromatographic determination of lansoprazole and its metabolites in human serum and urine.
  • Control of gastric corpus chromogranin A messenger RNA abundance in the rat.
  • Clinical application of gastric histology to monitor treatment of dual therapy in H. pylori eradication.
  • Effects of omeprazole and cimetidine on gastric acid secretion and right atrial beating frequency in isolated organ preparations from the guinea pig.
  • Pentadecapeptide BPC 157, cimetidine, ranitidine, bromocriptine, and atropine effect in cysteamine lesions in totally gastrectromized rats: a model for cytoprotective studies.
  • Gastric antisecretory activity of lansoprazole in different experimental models: comparison with omeprazole.
  • Endoscopic stage classification of peptic ulcer and characterization of the healing process by proton pump inhibitors
  • Gastric MALT lymphoma, clinical features
  • Prostaglandin stimulates Cl(-)-HCO3- exchange in amphibian oxynticopeptic cells.
  • Peak distortion in the column liquid chromatographic determination of omeprazole dissolved in borax buffer.
  • Ciprofloxacin-omeprazole combination therapy for eradication of Helicobacter pylori
  • Synthesis and anti-ulcer activity of some new compounds with arylthiomethyl-pyridine structure
  • Role of endothelin-1 and constitutive nitric oxide synthase in gastric mucosal resistance to indomethacin injury: effect of antiulcer agents.
  • Evaluation of omeprazole genotoxicity in a battery of in vitro and in vivo assays.
  • Stability of capsules containing omeprazole in enteric coated pellets.
  • Omeprazole: effective, convenient therapy for Zollinger-Ellison syndrome.
  • Intrahypothalamic corticotropin-releasing factor elevates gastric bicarbonate and inhibits stress ulcers in rats.
  • Effects of cimetidine on acute gastric mucosal injury induced by ischemia-reperfusion in rats.
  • Failure of oesophageal acid control in candidates for Barrett's oesophagus reversal on a very high dose of proton pump inhibitor.
  • Ionic dependence of adenosine uptake into cultured astrocytes.
  • Stimulation of electrogenic chloride secretion by prostaglandin E2 in guinea-pig isolated gastric mucosa.
  • High-performance thin-layer chromatographic method for the detection and determination of lansoprazole in human plasma and its use in pharmacokinetic studies.
  • Gastroesophageal reflux: A critical factor in pediatric subglottic stenosis.
  • Genetic polymorphism of CYP2C19 and lansoprazole pharmacokinetics in Japanese subjects.
  • DNA synthesis and genotoxicity.
  • Relative contributions of CYP2C9 and 2C19 to phenytoin 4-hydroxylation in vitro: inhibition by sulfaphenazole, omeprazole, and ticlopidine.
  • A discordance of the cytochrome P450 2C19 genotype and phenotype in patients with advanced cancer.
  • Activity inhibition of cytolytic lymphocytes by omeprazole.
  • Usefulness of every-other day administration of proton pump inhibitors from the standpoint of continuous 48-hour pH measurements-- Comparison of cimetidine, omeprazole, and lansoprazole
  • Effect of intermittent administration of omeprazole on serum pepsinogens in duodenal ulcer patients and healthy volunteers.
  • Autoradiographic demonstration of lansoprazole uptake sites in rat antrum and colon.
  • Sulfide and sulfoxide derivatives of substituted benzimidazoles inhibit acid formation in isolated gastric glands by different mechanisms.
  • Ethnic and genetic determinants of omeprazole disposition and effect.
  • Breath test in the diagnosis of Helicobacter pylori infection: concordance with histological methods and correlation with anatomopathological lesions of the gastric mucosa
  • Empirical therapy versus diagnostic tests in gastroesophageal reflux disease: a medical decision analysis.
  • Growth of the parathyroid glands in omeprazole-treated chickens.
  • Effect of omeprazole administration on pancreatic content of enzymes in rats
  • Nuclear uptake of the Ah (dioxin) receptor in response to omeprazole: transcriptional activation of the human CYP1A1 gene.
  • Effect of long-term administration of antisecretary drugs on rat gastric histamine synthesis and acid secretion--compare with omeprazole and cimetidine
  • Effect of short-term administration of omeprazole on serum gastrin and pepsinogens in antrectomized patients.
  • Cost of acid peptic disorders in a managed-care organization.
  • In vitro evaluation of dissolution properties and degradation products of omeprazole in enteric-coated pellets.
  • The influence of isolated doses of drugs, feeding and colonic bacterial ureolysis on urea breath test results.
  • Effects of acute administration of omeprazole or ranitidine on basal and vagally stimulated gastric acid secretion and alkalinization of the duodenum in anaesthetized cats.
  • Postprandial alkaline tide: does it exist?
  • Omeprazole, other antiulcer drugs and newly diagnosed gout.
  • Functional dyspepsia has a good prognosis irrespective of H. pylori status. Long-term follow-up of symptoms after anti H. pylori treatment.
  • Specific and dose-dependent enzyme induction by omeprazole in human beings.
  • Omeprazole in elderly duodenal ulcer patients: relationship between reduction in gastric acid secretion and fasting plasma gastrin.
  • HCO3- secretion in rat duodenum after treatment with omeprazole and ranitidine.
  • Gastric hyperemic response during vagally mediated acid secretion by TRH analog in rats.
  • In vitro activity of ebrotidine, ranitidine, omeprazole, lansoprazole, and bismuth citrate against clinical isolates of Helicobacter pylori.
  • Will Helicobacter pylori affect short-term rebleeding rate in peptic ulcer bleeding patients after successful endoscopic therapy?
  • CYP2C19 genotype related effect of omeprazole on intragastric pH and antimicrobial stability.
  • Mechanisms of stimulatory effect of neuromedin C on pancreatic exocrine secretion in conscious rats.
  • Effect of omeprazole on eicosanoid formation in and release from guinea-pig gastric mucosal cells.
  • Demonstration of the electrogenicity of proton translocation during the phosphorylation step in gastric H+K(+)-ATPase.
  • Membrane potential changes after infection of monocytes by Toxoplasma gondii.
  • Gastric endocrine cells and gastritis in patients receiving long-term omeprazole treatment.
  • Evidence that gastrin enhances 45Ca uptake into bone through release of a gastric hormone.
  • Gastric acid-independent enhancement of exocrine pancreatic secretion by dietary protein in chronic bile-pancreatic juice diverted rats.
  • Plasma gastrin and gastric enterochromaffinlike cell activation and proliferation. Studies with omeprazole and ranitidine in intact and antrectomized rats.
  • Proliferation of enterochromaffinlike cells in omeprazole-treated hypergastrinemic rats.
  • A new method for evaluating gastric ulcer healing by endoscopic ultrasonography.
  • The effect of omeprazole on gastric emptying in patients with duodenal ulcer disease.
  • The effect of omeprazole on gastric juice viscosity, pH and bacterial counts.
  • Laryngeal manifestations of gastroesophageal reflux before and after treatment with omeprazole.
  • Gastrin does not stimulate growth of the rat pancreas.
  • Characterization of Syrian hamster gastric mucosal H+,K+-ATPase.
  • Chronic gastric ulcer healing in rats subjected to selective and non-selective cyclooxygenase-2 inhibitors.
  • Development of a health-related quality-of-life questionnaire for individuals with gastroesophageal reflux disease: a validation study.
  • Properties of light and heavy vesicles simultaneously prepared from hog gastric mucosae.
  • Antisecretory and antiulcer effect of T-330, a novel reversible proton pump inhibitor, in rats.
  • Interaction between Helicobacter pylori and human gastric epithelial cells in culture: effect of antiulcer drugs.
  • Peptic ulcer and Helicobacter pylori. Comments on the authors' cases
  • Effect of curing Helicobacter pylori infection on intragastric pH during treatment with omeprazole.
  • Critical effect of Helicobacter pylori infection on the effectiveness of omeprazole for prevention of gastric or duodenal ulcers among chronic NSAID users.
  • Decision analysis of Helicobacter pylori eradication therapy using omeprazole with either clarithromycin or amoxicillin.
  • Lansoprazole reverses Helicobacter pylori-inhibited gastric epithelial cell growth.
  • Potentiation of hypericin and hypocrellin-induced phototoxicity by omeprazole.
  • Gastric metaplasia and Helicobacter pylori.
  • Activity of omeprazole on Helicobacter pylori and relation to toxicity of strains.
  • Metronidazole, omeprazole and clarithromycin: an effective combination therapy for Helicobacter pylori infection.
  • Helicobacter pylori eradication therapy for high-grade mucosa-associated lymphoid tissue lymphomas of the stomach with analysis of p53 and K-ras alteration and microsatellite instability.
  • High eradication rates in Helicobacter pylori infection in patients with duodenal ulcer who failed previous eradication therapy
  • Etiological involvement of Helicobacter pylori in "reflux" gastritis after gastrectomy.
  • Pharmacological therapy of Helicobacter pylori infection.
  • Simultaneous high-performance liquid chromatographic analysis of omeprazole and its sulphone and sulphide metabolites in human plasma and urine.
  • Nonlinear kinetics after high-dose omeprazole caused by saturation of genetically variable CYP2C19.
  • Proton pump inhibitors or histamine-2 receptor antagonists for the prevention of recurrences of erosive reflux esophagitis: a cost-effectiveness analysis.
  • Cytoprotective action of histamine against 0.6 N HCl-induced gastric mucosal injury in rats; comparative study with adaptive cytoprotection induced by exogenous acid.
  • Turnover of the gastric H+,K(+)-adenosine triphosphatase alpha subunit and its effect on inhibition of rat gastric acid secretion.
  • Regulation of peptide YY homeostasis by gastric acid and gastrin.
  • Lansoprazole and omeprazole have similar effects on plasma gastrin levels, enterochromaffin-like cells, gastrin cells and somatostatin cells in the rat stomach.
  • Helicobacter pylori eradication in the African setting, with special reference to reinfection and duodenal ulcer recurrence.
  • Disulfide cross-linking of H,K-ATPase opens Cl- conductance, triggering proton uptake in gastric vesicles. Studies with specific inhibitors.
  • Influence of acid and angiogenesis on kinetics of gastric ulcer healing in rats: interaction with indomethacin.
  • Omeprazole versus histamine H2 receptor antagonists in the treatment of acute upper non-variceal bleeding.
  • Effect of lansoprazole on human leukocyte function.
  • Enantioselective hydroxylation of omeprazole catalyzed by CYP2C19 in Swedish white subjects.
  • Effects of long-term hypergastrinaemia on the ultrastructure of enterochromaffin-like cells in the stomach of the rat, hamster and guinea pig.
  • Omeprazole-induced hypergastrinemia does not influence growth of colon carcinoma.
  • Gastric acid and pepsin hypersecretion in conscious rabbits.
  • Tritiated thymidine incorporation into DNA in rat gastric mucosal cells.
  • Peptic ulcer: changing indications for gastric resection during the last 15 years
  • Helicobacter pylori eradication in clinical practice: one-week low-dose triple therapy is preferable to classical bismuth based triple therapy.








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