Drugs online research references
Gastric mucosal apoptosis induced by ethanol: effect of antiulcer agents.
Gastric mucosal changes induced by long term infection with Helicobacter pylori in Mongolian gerbils: effects of bacteria eradication.
Helicobacter pylori infection in a pediatric population: in vitro susceptibilities to omeprazole and eight antimicrobial agents.
Reproducibility, validity, and responsiveness of a disease-specific symptom questionnaire for gastroesophageal reflux disease.
Enhancement of neutrophil infiltration in the corpus after failure of Helicobacter pylori eradication.
Omeprazole, a specific inhibitor of gastric (H+-K+)-ATPase, is a H+-activated oxidizing agent of sulfhydryl groups.
The effects of NorA inhibition on the activities of levofloxacin, ciprofloxacin and norfloxacin against two genetically related strains of Staphylococcus aureus in an in-vitro infection model.
Effects of 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid, an inhibitor of Cl(-)-HCO3- exchanger, on stress-induced gastric lesions in rats.
Proton pump inhibitor-associated gastric polyps: a retrospective analysis of their frequency, and endoscopic, histologic, and ultrastructural characteristics.
Differentiation among inhibitory actions of omeprazole, cimetidine, and SCN- on gastric acid secretion.
Relationship between eradication therapy and clarithromycin-resistant Helicobacter pylori in Japan.
Effect of proton pump inhibitors on the detection of Helicobacter pylori in gastric biopsies.
Effects of a proton pump inhibitor, AG-1749 (lansoprazole), on reflux esophagitis and experimental ulcers in rats.
Effect of omeprazole, an inhibitor of H+,K(+)-ATPase, on bone resorption in humans.
Omeprazole, a proton pump inhibitor, reduces the secretion, synthesis and gene expression of pepsinogen in the rat stomach.
Species comparison in P450 induction: effects of dexamethasone, omeprazole, and rifampin on P450 isoforms 1A and 3A in primary cultured hepatocytes from man, Sprague-Dawley rat, minipig, and beagle dog.
Importance of gastric acid in gastric ulcer formation in rabbits with antibody-induced prostaglandin deficiency.
Possible mechanism for the inhibition of gastric (H+ + K+)-adenosine triphosphatase by the proton pump inhibitor AG-1749.
Mechanisms of acid release in isolated gas gland cells of the European eel Anguilla anguilla.
Omeprazole and ranitidine, antisecretagogues with different modes of action, are equally effective in causing hyperplasia of enterochromaffin-like cells in rat stomach.
An evaluation of the CYP1A induction potential of pantoprazole in primary rat hepatocytes: a comparison with other proton pump inhibitors.
Interaction of drugs for eradication therapy against antibiotic-resistant strains of Helicobacter pylori.
Antiulcer drug prescribing in hospital successfully influenced by "immediate concurrent feedback".
Effect of omeprazole on interdigestive gastroduodenal motility of patients with ulcer-like dyspepsia.
Serum pepsinogens after interruption of long-term maintenance therapy with omeprazole in patients with reflux esophagitis.
Effect of omeprazole on intestinal output in the short bowel syndrome.
Role of 24 hour intraesophageal pH monitoring in diagnosis of gastroesophageal reflux and assessment of drug effectiveness
Effect of omeprazole on intragastric and duodenal bulb acidity in duodenal ulcer patients.
Pharmacokinetics of intravenous omeprazole in children.
Effect of once daily intravenous and oral omeprazole on 24-hour intragastric acidity in healthy subjects.
Contribution of cytosolic ionic and energetic milieu change to ischemia- and reperfusion-induced injury in guinea pig heart: fluorometry and nuclear magnetic resonance studies.
Determination of omeprazole in rat plasma by HPLC with column switching.
Bleeding from staple line erosion after esophageal transection: effect of omeprazole.
Application of proton pump inhibitor to special conditions; Zollinger-Ellison syndrome
Studies on (H(+)-K+)-ATPase inhibitors of gastric acid secretion. Prodrugs of 2-(2-pyridinylmethyl)sulfinylbenzimidazole proton-pump inhibitors.
Effect of an H+, K+-ATPase inhibitor, omeprazole (OPZ), on gastric acid secretion and gastric or duodenal lesion. Comparison with an H2-receptor antagonist, famotidine (FMD)
Intracellular binding is an important determinant of the avid hepatic uptake of the high clearance drug omeprazole.
Structure of 5-methoxy-2-(4-methoxy-3,5-dimethyl-2-pyridinyl) methylsulfinyl)-1H-benzimidazole (omeprazole).
Determination of omeprazole in pharmaceuticals by derivative spectroscopy.
Prolonged and profound acid inhibition is crucial in Helicobacter pylori treatment with a proton pump inhibitor combined with amoxicillin.
CYP3A4 is the major CYP isoform mediating the in vitro hydroxylation and demethylation of flunitrazepam.
Difference between two isozymes of (Na+ + K+)-ATPase in the interaction with omeprazole.
Ouabain-insensitive K-adenosine triphosphatase in distal nephron segments of the rabbit.
Prospective study of erradication of Helicobacter pylori in patients with duodenal ulcer: analysis of antral and gastric body biopsies
Inhibition of gastric K+/H+-ATPase by acid-activated 2-((2-pyridylmethyl)sulphinyl)benzimidazole products.
Inhibition of gastric (H+ + K+)-ATPase by the substituted benzimidazole, picoprazole.
Oxidative metabolism of lansoprazole by human liver cytochromes P450.
The pharmacodynamics of lansoprazole administered via gastrostomy as intact, non-encapsulated granules.
Inhibitory action of lansoprazole and its analogs against Helicobacter pylori: inhibition of growth is not related to inhibition of urease.
Determination of lansoprazole and its metabolites in plasma by high-performance liquid chromatography using a loop column.
Pharmacokinetics of lansoprazole in patients with renal or liver disease of varying severity.
Dose-response effect of lansoprazole in patients with Zollinger-Ellison syndrome
Diagnosis and therapy of laryngitis gastrica
Clinical evolution of laryngeal granulomas: treatment and prognosis.
Bouginage of peptic esophageal stenoses. Results of one year with long-term omeprazole medication
Course of histological lesions of the gastric mucosa after eradication of H. pylori in patients with duodenal ulcer. Initial study and 6-month follow-up
A simple high performance liquid chromatography assay for simultaneous determination of omeprazole and metronidazole in human plasma and gastric fluid.
Potential hazards of long-term acid suppression.
Temporary cessation of long-term maintenance treatment with omeprazole in patients with H2-receptor-antagonist-resistant reflux oesophagitis. Effects on symptoms, endoscopy, serum gastrin, and gastric acid output.
Serum gastrin levels during long-term omeprazole treatment.
Antibacterial properties of lansoprazole alone and in combination with antimicrobial agents against Helicobacter pylori.
Treatment of gastric MALT lymphoma by Helicobacter pylori eradication: a study controlled by endoscopic ultrasonography.
Synergic interactions of macrolides and proton-pump inhibitors against Helicobacter pylori: a comparative in-vitro study.
Bile reflux in benign and malignant Barrett's esophagus: effect of medical acid suppression and nissen fundoplication.
Proton pump inhibitor for maintenance therapy of peptic ulcer
Treatment of Barrett esophagus with argon plasma coagulation with acid suppression--a prospective study
Effects of H2-receptor antagonists upon physiological acid secretory states in animals.
Histamine H2-receptor mediated stimulation of gastric acid secretion by mercaptomethylimidazole.
Ticlopidine as a selective mechanism-based inhibitor of human cytochrome P450 2C19.
Economic evaluation of new medical technology.
Pharmacokinetics and metabolism of omeprazole in man.
Phenocopies of poor metabolizers of omeprazole caused by liver disease and drug treatment.
Lansoprazole and ethanol metabolism: comparison with omeprazole and cimetidine.
Evaluation of combined antibiotic-omeprazole therapies in Helicobacter pylori-infected Mongolian gerbils.
Omeprazole and dry mouth.
Antiulcer drugs and gastric mucosal integrity. Effects of misoprostol, 16,16-dimethyl PGE2, and cimetidine on hemodynamics and metabolic rate in canine gastric mucosa.
Adenocarcinoma of the rat esophagus in the presence of a proton pump inhibitor: a pilot study.
Targeting the fungal plasma membrane proton pump.
Restoration of squamous mucosa after ablation of Barrett's esophageal epithelium.
Co-purification of gastric mucoproteins with DNA: an explanation for the reported 'interaction' of omeprazole with DNA in rat tissues.
Influence of anti-Helicobacter triple-therapy with metronidazole, omeprazole and clarithromycin on intestinal microflora.
Cytoprotective effect of NC-1300-O-3 against gastric lesions induced by necrotizing agents in rats.
Conformational analysis: a new approach by means of chemometrics.
Omeprazole and dietary nitrate independently affect levels of vitamin C and nitrite in gastric juice.
Bacterial formation of N-nitroso compounds in the rat stomach after omeprazole-induced achlorhydria.
Omeprazole inhibits nocturnal and pentagastrin-stimulated gastric secretion in man.
Previous use of non-steroidal anti-inflammatory drugs and anticoagulants: the influence on clinical outcome of bleeding gastroduodenal ulcers.
Does concurrent acute ethanol ingestion during omeprazole therapy affect pituitary gonadal axis in male subjects?
Carbonic anhydrase in the normal rat stomach and duodenum and after treatment with omeprazole and ranitidine.
Lack of gastric toxicity of nitric oxide-releasing aspirin, NCX-4016, in the stomach of diabetic rats.
Optimizing the information obtained from continuous 24-hour gastric pH monitoring.
Nonsteroidal anti-inflammatory drug and phospholipid prodrugs: combination therapy with antisecretory agents in rats.
Prolonged remission of oesophagitis does not alter the magnitude of oesophageal acid exposure.
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Endoscopic characteristics of low-grade gastric mucosa-associated lymphoid tissue lymphoma after eradication of Helicobacter pylori.
Pharmacokinetic comparison of omeprazole capsules and a simplified omeprazole suspension.
Discovery and development of the proton pump inhibitor
Effects of the enantiomers of lansoprazole (AG-1749) on (H+ + K+)-ATPase activity in canine gastric microsomes and acid formation in isolated canine parietal cells.
Effects of omeprazole on ethanol metabolism: an in vitro and in vivo rat and human study.
Omeprazole inhibits growth of cancer cell line of colonic origin.
B-cell lymphoma (MALToma) of the stomach and Helicobacter pylori infection
Identification of the site of inhibition by omeprazole of a alpha-beta fusion protein of the H,K-ATPase using site-directed mutagenesis.
Effects of cimetidine and omeprazole on angiogenesis in granulation tissue of acetic acid-induced gastric ulcers in rats.
Studies on the effects of omeprazole on thyroid function in the rat.
Effects of leminoprazole, omeprazole and sucralfate on indomethacin-induced delayed healing of kissing gastric ulcers in rats.
The effect of ammonia on omeprazole-induced reduction of gastric acidity in subjects with Helicobacter pylori infection.
Effect of cimetidine and omeprazole on aspirin- and taurocholate-induced gastric mucosal damage in the rat.
First-pass metabolism of omeprazole in rats.
One-week treatment with omeprazole, clarithromycin and amoxicillin: high efficacy in the eradication of Helicobacter pylori and cicatrization of duodenal ulcer
Clinico-pharmacological evaluation of omeprazole, as a proton pump inhibitor, compared with H2-blockers
Inhibition of 14C-aminopyrine accumulation in isolated rabbit gastric glands by the H2-receptor antagonist HOE 760 (TZU-0460).
Mechanism of action of omeprazole.
Effect of enprostil on omeprazole-induced hypergastrinemia and inhibition of gastric acid secretion in peptic ulcer patients.
The effect of omeprazole-induced hypergastrinemia on the oxyntic mucosa of mastomys.
Relationship of omeprazole-induced hypergastrinemia to gastric pH.
Modified combined omeprazole/amoxicillin therapy for Helicobacter pylori eradication: a pilot study
Comparison of the antisecretory effects of omeprazole when administered intravenously, as acid-stable granules and as an oral paste in horses.
The specificity of omeprazole as an (H+ + K+)-ATPase inhibitor depends upon the means of its activation.
Differences in the antisecretory actions of the proton pump inhibitor AG-1749 (lansoprazole) and the histamine H2-receptor antagonist famotidine in rats and dogs.
Effect of long-term omeprazole treatment on antral G and D cells in children.
Effect of high dose omeprazole on gastric pepsin secretion and serum pepsinogen levels in man.
Catalysis of oxygen-18 exchange between inorganic phosphate and water by the gastric H,K-ATPase.
Prolonged effect of omeprazole on the 14C-urea breath test.
An acid-independent antiulcer effect of M1 antimuscarinics in the rat.
The efficacy of the omeprazole-levosulpiride combination in the therapy of distal reflux esophagitis
Effect of short-term omeprazole administration on serum pepsinogens in relation to fasting serum gastrin and gastric acid secretion.
Effects of NaSCN and omeprazole on resistance and potential of fundus of Rana pipiens.
Optimal dose of oral omeprazole for maximal 24 hour decrease of intragastric acidity.
In vitro studies on omeprazole metabolism in rat liver microsomes
Rectal absorption of omeprazole from suppository in humans.
The hydroxylation of omeprazole correlates with S-mephenytoin and proguanil metabolism.
Relaxation induced by omeprazole does not change in diabetic rabbit corpus cavernosum.
Identification and expression of prohormone-converting enzymes in the rat stomach.
Omeprazole in H2 receptor antagonist-resistant reflux esophagitis.
Inhibition of iron absorption by omeprazole in rat model.
Oral bioavailability of omeprazole before and after chronic therapy in patients with duodenal ulcer.
Maintenance therapy with antiulcer drugs: review of 71 cases
Extent and variation of omeprazole prescribing in an elderly population of Ontario.
One-week treatment with omeprazole, clarithromycin, and metronidazole in children with Helicobacter pylori infection.
Comparison of IY81149 with omeprazole in rat reflux oesophagitis.
Effects of misoprostol and omeprazole on basal gastric pH and free acid content in horses.
Animal pharmacodynamics of omeprazole. A survey of its pharmacological properties in vivo.
Empiric trial of high-dose omeprazole in patients with posterior laryngitis: a prospective study.
Effects of antimuscarinic agents, H2-blockers and omeprazole on rat chronic gastric ulcer after long- and short-term administration.
The effects of rabeprazole on parietal cells and enterochromaffin-like cells in rats: a comparison with omeprazole.
Cytological transformations associated with parietal cell stimulation: critical steps in the activation cascade.
Gastrin-mediated effects of omeprazole on rat colon mucosa.
Effects of acid suppression and bismuth medications on the performance of diagnostic tests for Helicobacter pylori infection.
Continued (5-year) followup of a randomized clinical study comparing antireflux surgery and omeprazole in gastroesophageal reflux disease.
AHR-9294: a novel inhibitor of H,K-ATPase antagonizes gastric HCl secretion in vivo.
Short report: the effect of omeprazole on Helicobacter pylori and associated gastritis.
Repeated high oral doses of omeprazole do not affect intrinsic factor secretion: proof of a selective mode of action.
Omeprazole in the treatment of Zollinger-Ellison syndrome: a 4-year international study.
Pharmacology and toxicology of omeprazole--with special reference to the effects on the gastric mucosa.
Effects of omeprazole and famotidine on (H+-K+) ATPase and acid secretion in rabbit gastric glands
Microelectrode measurements of K+ and pH in rabbit gastric glands: effect of histamine.
Mechanisms of protection by omeprazole against experimental gastric mucosal damage in rats.
Different biochemical modes of action of two irreversible H+,K(+)-ATPase inhibitors, omeprazole and E3810.
Influence of bafilomycin A1 on pHi responses in cultured rabbit nonpigmented ciliary epithelium.
Antisecretory effect and oral pharmacokinetics following low dose omeprazole in man.
Effect of intravenous and oral omeprazole on 24-hour intragastric acidity in duodenal ulcer patients.
Detection of ouabain-insensitive H(+)-transporting, K(+)-stimulated p-nitrophenylphosphatase activity in rat gastric glands by cerium-based cytochemistry.
Omeprazole inhibits oxidative drug metabolism. Studies with diazepam and phenytoin in vivo and 7-ethoxycoumarin in vitro.
Omeprazole: effects on oxidative drug metabolism.
Cimetidine and omeprazole accelerate gastric ulcer healing by an increase in gastrin secretion.
Effect of omeprazole and feeding on plasma gastrin in patients with achlorhydria.
Somatostatin cells in the oxyntic mucosa of hypo- or hypergastrinemic rats.
Assessment of cytochrome P450 activity by a five-drug cocktail approach.
Feedback control of pancreatic secretion in rats. Role of gastric acid secretion.
Chiral resolution of pantoprazole sodium and related sulfoxides by complex formation with bovine serum albumin in capillary electrophoresis.
Function and structure of parietal cells after H+-K+-ATPase blockade.
Helicobacter pylori in patients with systemic sclerosis: detection with the 13C-urea breath test and eradication.
Respiratory symptoms in patients with gastroesophageal reflux disease following medical therapy and following antireflux surgery.
Characterization of peanut-lectin (+) cells derived from the RCCT-28A cell line.
The effect of pentadecapeptide BPC 157, H2-blockers, omeprazole and sucralfate on new vessels and new granulation tissue formation.
Effect of inhibition of pentagastrin-stimulated acid secretion on gastric mucosal gland luminal pressure.
Antiulcerogenicity of the flavonoid fraction from Bidens aurea: comparison with ranitidine and omeprazole.
Diagnostic value of serum pepsinogen C in patients with raised serum concentrations of pepsinogen A.
Nonparallel secretion of pepsinogen and acid by gastric oxyntopeptic cells of the toad (Bufo marinus).
Omeprazole increases permeability across isolated rat gastric mucosa pre-treated with an acid secretagogue.
Pharmacokinetic-pharmacodynamic study of oral lansoprazole in children.
Comparative pharmacokinetic/pharmacodynamic analysis of proton pump inhibitors omeprazole, lansoprazole and pantoprazole, in humans.
Lansoprazole pharmacokinetics in subjects with various degrees of kidney function.
Biochemical and pharmacological properties of a newly synthesized proton pump (H+/K(+)-ATPase) inhibitor, TY-11345 in experimental animals.
Biochemical and pharmacological properties of a new proton pump inhibitor, 2-amino-4,5-dihydropyrido1,2-athiazolo 5,4-g benzimidazole (YJA20379-5).
CYP2C19 genotype and phenotype determined with omeprazole in patients with acid-related disorders with and without Helicobacter pylori infection.
Effects of lansoprazole on pharmacokinetics and metabolism of theophylline.
Gastric mucosal function following withdrawal of omeprazole in rats.
Inhibition of the plasma-membrane H(+)-ATPase from Dunaliella adidophila by omeprazole.
Effects of arachidonic acid, prostaglandins, retinol, retinoic acid and cholecalciferol on xenobiotic oxidations catalysed by human cytochrome P450 enzymes.
Effect of clarithromycin and other macrolides on the sulfoxidation and 5-hydroxylation of lansoprazole in dogs.
Signal transduction-mediated CYP1A1 induction by omeprazole in human HepG2 cells.
Analysis of indications and diagnosis of the gastroscopies requested by primary care physicians
Inhibition of transketolase and pyruvate decarboxylase by omeprazole.
Studies on the mechanism of action of A80915A, a semi-naphthoquinone natural product, as an inhibitor of gastric (H(+)-K+)-ATPase.
Analysis of gastrin receptor gene expression in proliferating cells in the neck zone of gastric fundic glands using laser capture microdissection.
Effects of IY-81149, a newly developed proton pump inhibitor, on gastric acid secretion in vitro and in vivo.
Impact of a formulary change in proton pump inhibitors on health care costs and patients' symptoms.
Endoscopic topical therapy for the treatment of Helicobacter pylori infection.
Duodenal fat intensifies the perception of heartburn.
Hypergastrinemia in response to gastric inflammation suppresses somatostatin.
The effect of immobilization stress on the pharmacokinetics of omeprazole in rats.
Studies on the mechanism of action of the omeprazole-derived cyclic sulphenamide.
Wine stimulates gastric acid secretion in isolated rabbit gastric glands via two different pathways.
The gastric mucigenous function in the treatment of patients with ulcer with various antisecretory preparations
Nature of the gastric acid-gastrin feedback loop in the fetal sheep.
Prevalence of H. pylori-infection in family members of H. pylori positive and its influence on the reinfection rate after successful eradication therapy: a two-year follow-up.
Treatment of gastritis-associated Helicobacter pylori infection in children
Effect of omeprazole on oral and intravenous RS-methadone pharmacokinetics and pharmacodynamics in the rat.
Mechanism of gastric alkaline response in the stomach after damage. Roles of nitric oxide and prostaglandins.
Studies on the mechanism of action of the gastric microsomal (H+ + K+)-ATPase inhibitors SCH 32651 and SCH 28080.
Effect of various antisecretory drugs on morphological changes in rat gastric mucosa in experimental stomach ulcers
Effects of prostaglandin D2 and omeprazole on indomethacin-induced gastric ulcers in rats.
Antibiotic resistance of Helicobacter pylori in Reunion Island: therapeutic consequences
Determination of omeprazole and metabolites in plasma and urine.
Normalization of phospholipids concentration of the gastric mucosa was observed in patients with peptic ulcer after eradication of Helicobacter pylori.
Low efficacy of an ultra-short term, once-daily dose triple therapy with omeprazole, azithromycin, and secnidazole for Helicobacter pylori eradication in peptic ulcer.
Impact of proton pump inhibitor utilization patterns on gastroesophageal reflux disease-related costs.
Protective effect of omeprazole against acute gastric mucosal lesions induced by compound 48/80, a mast cell degranulator, in rats.
Effect of basolateral acidification on the frog oxynticopeptic cell.
Inhibition of cerebrospinal fluid formation by omeprazole.
Severity of esophageal eosinophilia predicts response to conventional gastroesophageal reflux therapy.
A cell-based reporter gene assay for determining induction of CYP3A4 in a high-volume system.
Submicroscopic aspects of the mechanism of inhibitors of H+/K+-ATPase in gastric parietal cells
Development and preliminary application of a high-performance liquid chromatographic assay for omeprazole metabolism in human liver microsomes.
Coordinated regulation of gastric chloride secretion with both acid and alkali secretion.
Prospective study on the incidence of chronic ear complaints related to gastroesophageal reflux and on the outcome of antireflux therapy.
Medium-term results of oral and intravenous omeprazole/amoxicillin Helicobacter pylori eradication therapy.
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Long-term curative effects of suture plus proximal gastric vagotomy or triad-therapy for duodenal ulcer with acute perforation
Omeprazole has no effect on acetaminophen kinetics in the rat.
Omeprazole, furazolidone, and tetracycline: an eradication treatment for resistant H. pylori in Brazilian patients with peptic ulcer disease.
Increased hepatocyte growth factor content in rat stomach during omeprazole treatment.
Persistent acid reflux and symptoms in patients with Barrett's oesophagus on proton-pump inhibitor therapy.
Microcirculation in gastric mucosa as related to its secretory activity in patients with peptic ulcer
Factors affecting ammonium uptake by C11 clone of MDCK cells.
Effect of nizatidine 300 mg at night and omeprazole 20 mg in the morning on 24-hour intragastric pH and bacterial overgrowth in patients with acute duodenal ulcer.
Modulation of the phototoxic effect of hypericin in human leukemia CEM cell line by N-ethylmaleimide, amiloride and omeprazole.
Effect of proton pump inhibitors on the continuous real time (13)C-urea breath test.
A novel antioxidant and antiapoptotic role of omeprazole to block gastric ulcer through scavenging of hydroxyl radical.
Hydrogen-potassium ATPase inhibitors induce relaxation on rabbit prostatic strips in vitro.
Anti-Helicobacter pylori therapy in India: differences in eradication efficiency associated with particular alleles of vacuolating cytotoxin (vacA) gene.
Monotherapy with mastic does not eradicate Helicobacter pylori infection from mice.
Esophageal clearance function following treatment of esophagitis.
In vitro study on capsule formulations of omeprazole containing enteric coated granules.
Differences in pH-dependent activation rates of substituted benzimidazoles and biological in vitro correlates.
Characterization of CYP2C19 and CYP2C9 from human liver: respective roles in microsomal tolbutamide, S-mephenytoin, and omeprazole hydroxylations.
Long-term follow-up of gastric metaplasia after eradication of Helicobacter pylori.
Gene expression of ornithine decarboxylase, cyclooxygenase-2, and gastrin in atrophic gastric mucosa infected with Helicobacter pylori before and after eradication therapy.
The state of immune system and effects of current therapy and immunomodulators
Evaluation of omeprazole as a cost-effective diagnostic test for gastro-oesophageal reflux disease.
The effect of commonly used drugs on angiogenesis.
Bioactivation of cyclophosphamide: the role of polymorphic CYP2C enzymes.
Type 2 diabetes mellitus affects eradication rate of Helicobacter pylori.
Effect of acid blockade on gastric histamine in mice.
Refinement of, and new applications for, Helicobacter pylori colonization in pig gastric biopsy specimens cultured in vitro.
Globus sensation and gastroesophageal reflux.
Nodular gastritis in adults is caused by Helicobacter pylori infection.
General practitioners' approach to dyspepsia. Survey of consultation frequencies, treatment, and investigations.
Antralization at the edge of proximal gastric ulcers: does Helicobacter pylori infection play a role?
The clinical role of cytochrome p450 genotypes in Helicobacter pylori management.
Gastric transitional zones, areas where Helicobacter treatment fails: results of a treatment trial using the Sydney strain mouse model.
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Synthesis of (aryloxy)alkylamines. 1. Novel antisecretory agents with H+K+-ATPase inhibitory activity.
Determination of omeprazole in bulk and injectable preparations by liquid chromatography.
Chloride transport of frog gastric fundus: effects of omeprazole.
Effectiveness of eradication anti-helicobacter therapy in patients with duodenal ulcer in different drug dosage regimens
Odds of moderate or severe gastric ulceration in racehorses receiving antiulcer medications.
Pharmacotherapy in complex treatment of ulcerous stenosis
Absence of an inhibitory effect of omeprazole and nizatidine on phenytoin disposition, a marker of CYP2C activity.
Impact of cotherapy with some proton pump inhibitors on medical claims among HMO patients already using other common drugs also cleared by cytochrome P450.
Polymorphic hydroxylation of S-mephenytoin and omeprazole metabolism in Caucasian and Chinese subjects.
Possible mechanisms for (H+ + K+)-ATPase inhibition by proton pump inhibitors, omeprazole, lansoprazole and SCH 28080
New fluorescent probes E3810 and methoxy E3810 for determining distributions of the apical membrane and the acidic compartment of gastric acid secreting cells.
Effects of omeprazole on the number of immunoreactive gastrin- and somatostatin-cells in the rat gastric mucosa.
Long-term persistence of resistant Enterococcus species after antibiotics to eradicate Helicobacter pylori.
Indomethacin damage to rat gastric mucosa is markedly dependent on luminal pH.
Relaxant effect of omeprazole and lansoprazole in guinea pig gallbladder muscle strips in vitro.
Four-day quadruple therapy as a routine treatment for Helicobacter pylori infection.
Sildenafil, a phosphodiesterase-5 inhibitor, delays gastric emptying and gastrointestinal transit of liquid in awake rats.
Divalent cations regulate acidity within the lumen and tubulovesicle compartment of gastric parietal cells.
Effect of a gastrin/cholecystokinin B receptor antagonist, S-0509, on the omeprazole-induced proliferation of gastric mucosa in rats.
Studies on the metabolism of omeprazole in the rat using liquid chromatography/ionspray mass spectrometry and the isotope cluster technique with 34Someprazole.
Study of protein assimilation, using stable isotope techniques.
24-hour intragastric acidity and plasma gastrin during long-term treatment with omeprazole or ranitidine in patients with reflux esophagitis.
Histidine decarboxylase gene expression in rat fundus is regulated by gastrin.
Risk of gynaecomastia associated with cimetidine, omeprazole, and other antiulcer drugs.
Antibacterial effect of garlic and omeprazole on Helicobacter pylori.
Influence of Cl- on pH(i) in oxynticopeptic cells of in vitro frog gastric mucosa.
24-hour intragastric acidity and plasma gastrin after omeprazole treatment and after proximal gastric vagotomy in duodenal ulcer patients.
Time course of inhibition of gastric acid secretion by omeprazole and ranitidine in gastric fistula rats.
Human gastric acid secretion following repeated doses of AG-1749.
Inhibition of acid secretion in guinea pigs by tricyclic antidepressants: comparison with ranitidine and omeprazole.
Influence of the stimulation state of the parietal cells on the inhibitory effect of omeprazole on gastric acid secretion in dogs.
Gastric ECL-cell hyperplasia and carcinoids in rodents following chronic administration of H2-antagonists SK&F 93479 and oxmetidine and omeprazole.
The mechanism for inhibition of gastric (H+ + K+)-ATPase by omeprazole.
Omeprazole: its influence on gastric acid secretion, gastrin and ECL cells.
Influence of prostaglandins, omeprazole, and indomethacin on healing of experimental gastric ulcers in the rat.
Effect of indomethacin on gastric mucosal blood flow around acetic acid-induced gastric ulcers in rats.
Modelling of colonic Cl- and K+ transport under resting and secreting conditions.
Effect of oral omeprazole on serum gastrin and serum pepsinogen I levels.
Gastroprotective activity of the novel proton pump inhibitor lansoprazole in the rat.
Iron-deficiency anemia associated with Helicobacter pylori gastritis.
Healing and relapse rates of duodenal ulcer with omeprazole vs ranitidine.
Chronic cough and hoarseness in patients with severe gastroesophageal reflux disease. Diagnosis and response to therapy.
Baclofen therapy for chronic hiccup.
The omeprazole treatment of patients with diseases of the upper digestive tract
Highly significant change of the clinical course of relapsing and complicated peptic ulcer disease after cure of Helicobacter pylori infection.
Differential effects of Na+, K(+)-ATPase inhibition by ouabain on acid secretory responses to histamine and bethanechol in the mouse isolated stomach.
Synthesis of 2-(4-fluoroalkoxy-2-pyridyl)methylsulfinyl-1H- benzimidazoles as antiulcer agents.
Endoscopic ultrasonographic (EUS) evaluation of the quality of gastric ulcer healing.
Regression of columnar lined (Barrett's) oesophagus with continuous omeprazole therapy.
Long-term omeprazole therapy does not affect Helicobacter pylori status in most patients.
The effect of omeprazole on healing of duodenal ulcers, Helicobacter pylori and gastritis
Long-term omeprazole therapy in peptic ulcer disease: gastrin, endocrine cell growth, and gastritis.
Induction of cytochrome P450 3A (CYP 3A) by E 5110, a non-steroidal anti-inflammatory agent (NSAID), and typical CYP 3A inducers in primary cultures of dog hepatocytes.
Reversible inhibition of rat gastric H+/K+-ATPase by T-330, 2-2-dimethylaminobenzyl)sulfinyl-1-(3-methylpyridine-2-yl)imidazole.
One-week triple therapy with omeprazole, amoxycillin and either clarithromycin or metronidazole for cure of Helicobacter pylori infection.
Mechanisms behind changes in gastric acid and bicarbonate outputs during the human interdigestive motility cycle.
The chemotherapeutic effects of H+/K+ inhibitors on Helicobacter pylori infection.
Effects of inhibition of gastric secretion on antral gastrin and somatostatin gene expression in rats.
Omeprazole produces parietal cell hypertrophy and hyperplasia in humans.
Duodenogastric reflux causes growth stimulation of foregut mucosa potentiated by gastric acid blockade.
Studies on the interrelation between Zollinger-Ellison syndrome, Helicobacter pylori, and proton pump inhibitor therapy.
Omeprazole potentiates atracurium and succinylcholine paralysis in vivo in rats.
Prevention of recurrences of erosive reflux esophagitis: a cost-effectiveness analysis of maintenance proton pump inhibition.
Gastric acid secretion is augmented by the replacement of extracellular Na+ with K+ or other ions.
Effectiveness of short-term triple therapy for healing Helicobacter pylori infection in ulcer disease
Signal transduction-mediated activation of the aryl hydrocarbon receptor in rat hepatoma H4IIE cells.
Oral SIV, SHIV, and HIV type 1 infection.
Appearance of myofibroblasts in the gastric mucosa after ingestion of ethanol and lansoprazole with reevaluation of the mucoid cap.
Effects of omeprazole on gastric mucosal blood flow in the conscious rat.
Protection of gastric epithelial cell monolayers from a human cell line by omeprazole in vitro.
Interference on Helicobacter pylori growth and adhesion by omeprazole and other drugs.
Mesalazine release from a pH dependent formulation: effects of omeprazole and lactulose co-administration.
Different acid secretagogues activate different Na+/H+ exchanger isoforms in rabbit parietal cells.
Rebound hypersecretion after omeprazole and its relation to on-treatment acid suppression and Helicobacter pylori status.
Effect of CYP2C19 polymorphism on serum levels of vitamin B12 in patients on long-term omeprazole treatment.
Effect of omeprazole and polyethylene glycol-400 on antipyrine elimination by the isolated perfused rat liver.
Wrong-way swallowing as a possible cause of bronchitis in patients with gastroesophageal reflux disease.
Photodynamic therapy in Barrett's esophagus: reduction of specialized mucosa, ablation of dysplasia, and treatment of superficial esophageal cancer.
Clinical efficacy of proton pump inhibitor therapy in neurologically impaired children with gastroesophageal reflux: prospective study.
Very early detection of RET proto-oncogene mutation is crucial for preventive thyroidectomy in multiple endocrine neoplasia type 2 children: presence of C-cell malignant disease in asymptomatic carriers.
Effects of omeprazole on gastric mucosal growth and differentiation in developing rat.
Characteristic features of proton pump inhibitors in the inhibition of gastric acid secretion: long-acting and complete inhibition
High doses of ranitidine in patients with reflux oesophagitis.
Ultrastructure of inhibited parietal cells in the rat.
Eradication of Helicobacter pylori with clarithromycin and omeprazole.
Identification of the human P450 enzymes involved in lansoprazole metabolism.
Eradication of helicobacter pylori among patients from a primary care practice.
Inhibition by omeprazole of proguanil metabolism: mechanism of the interaction in vitro and prediction of in vivo results from the in vitro experiments.
Why are patients prescribed proton pump inhibitors? Retrospective analysis of link between morbidity and prescribing in the General Practice Research Database.
Influencing prescribing practices and associated outcomes utilizing the drug use evaluation process.
Use of omeprazole for premedication
Effects of YJA20379-4 on gastric secretion, Helicobacter pylori growth and various gastric and duodenal lesions in rats.
Use of a five-day test to predict the long-term effects of gastric antisecretory agents on serum gastrin in rats.
The effect of omeprazole pretreatment on acetaminophen metabolism in rapid and slow metabolizers of S-mephenytoin.
Na+/H+ antiporter is the primary proton transport system used by osteoclasts during bone resorption.
Comparative tolerability profile of omeprazole in clinical trials.
Genotoxicity and cell proliferative activity of omeprazole in rat stomach mucosa.
Involvement of heat shock proteins in the healing of acetic acid-induced gastric ulcers in rats.
Lansoprazole, a novel benzimidazole proton pump inhibitor, and its related compounds have selective activity against Helicobacter pylori.
Effect of substituted benzimidazoles on acid secretion in isolated and enriched guinea pig parietal cells.
Prevalence of potential proton-pump inhibitor drug interactions: a retrospective review of prescriptions in community pharmacies.
Omeprazole-induced pseudohypertrophy of gastric parietal cells.
Regression of primary gastric lymphoma of mucosa-associated lymphoid tissue type after cure of Helicobacter pylori infection. MALT Lymphoma Study Group.
Current or recent proton pump inhibitor therapy markedly impairs the accuracy of the 14Curea breath test.
Omeprazole, Helicobacter pylori status, and alterations in the intragastric milieu facilitating bacterial N-nitrosation.
Second-line Helicobacter pylori eradication with a furazolidone-based regimen in patients who have failed a metronidazole-based regimen.
Gastrin cell responses to acidification of the achlorhydric rat stomach.
Impact of Helicobacter pylori and Giardia lamblia infections on chronic urticaria.
Effect of Helicobacter pylori eradication on gastritis in relation to cagA: a prospective 1-year follow-up study.
Effect of Helicobacter pylori eradication on gastric histology, serum gastrin and pepsinogen I levels, and gastric emptying in patients with gastric ulcer.
Effect of Helicobacter pylori on gastric epithelial apoptosis
Treatment of Helicobacter pylori infection in clinical practice in the United States: results from 224 patients.
Influence of Helicobacter pylori infection on healing and relapse of acetic acid ulcers in Mongolian gerbils.
The role of endogenous gastrin in the development of enterochromaffin-like cell carcinoid tumors in Mastomys natalensis: a study with the specific gastrin receptor antagonist AG-041R.
Rx drugs
Effect of omeprazole on H. pylori after two weeks of treatment.
Molecular modelling and quantitative structure-activity relationship studies on the interaction of omeprazole with cytochrome P450 isozymes.
Effect of cimetidine, ranitidine, famotidine and omeprazole on hepatocyte proliferation in vitro.
Effects of omeprazole and ranitidine on gastric acid secretion, blood gastrin levels and 3H-thymidine incorporation in the oxyntic mucosa from dogs and rats.
A study on the relation between proton pump inhibitor and gastric giardiasis.
Gastroduodenal ulcers in rats induced by 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP): requirement for gastric acid secretion and the role of prostaglandins.
Protease-activated receptor-2 (PAR-2) in the rat gastric mucosa: immunolocalization and facilitation of pepsin/pepsinogen secretion.
H+ transport by reconstituted gastric (H+ + K+)-ATPase.
H2-receptor antagonist reduces food intake and weight gain in rats by non-gastric acid secretory mechanisms.
Regression of duodenal gastric metaplasia in Helicobacter pylori positive patients with duodenal ulcer disease.
Stimulation of gastric bicarbonate secretion by an analog of thyrotropin-releasing hormone, YM-14673, in the rat.
Increased acid and bile reflux in Barrett's esophagus compared to reflux esophagitis, and effect of proton pump inhibitor therapy.
Evidence for a common binding site for omeprazole and N-ethylmaleimide in subunit A of chromaffin granule vacuolar-type H(+)-ATPase.
Effect of omeprazole on regional and temporal variations in intragastric acidity.
Helicobacter pylori reinfection is rare in peptic ulcer patients cured by antimicrobial therapy.
Helicobacter pylori of remnant stomach and optimal dose of amoxicillin for eradicating Helicobacter pylori.
Effect of single and repeated intravenous doses of omeprazole on pentagastrin stimulated gastric acid secretion and pharmacokinetics in man.
Helicobacter pylori of the remnant stomach and its eradication.
Morphometric assessment of reflux oesophagitis in fibreoptic biopsy specimens.
Secretory and biosynthetic responses of gastrin and somatostatin to acute changes in gastric acidity.
Omeprazole, a specific gastric secretion inhibitor on oxynticopeptic cells, reduces gizzard erosion in broiler chicks fed with toxic fish meals.
Impact of clarithromycin resistance on the effectiveness of a regimen for Helicobacter pylori: a prospective study of 1-week lansoprazole, amoxycillin and clarithromycin in active peptic ulcer.
Acquisition of secondary resistance after failure of a first treatment of Helicobacter pylori infection in children
Omeprazole induces altered bile acid metabolism.
The liver regenerative response elicited by antisecretory agents in partially hepatectomized rats: a comparison between omeprazole and famotidine.
Antacid provides better restoration of glandular structures within the gastric ulcer scar than omeprazole.
Biomarker studies in reversed Barrett's esophagus.
Gastrin effects on isolated rat enterochromaffin-like cells following long-term hypergastrinaemia in vivo.
Presumed laryngo-pharyngeal reflux: investigate or treat?
Thioredoxin and thioredoxin reductase show function-related changes in the gastric mucosa: immunohistochemical evidence.
Long-term consequences with regard to clinical outcome and cost-effectiveness of episodic treatment with omeprazole or ranitidine for healing of duodenal ulcer.
Modern diagnosis of gastroesophageal reflux disease (GERD).
Long-term efficacy and safety of omeprazole in patients with Zollinger-Ellison syndrome: a prospective study.
Movement of gastric acid secretion and influence of proton pump inhibitors on histamine H2 receptor antagonist resistant ulcer
The regulation of gastrin secretion in the chicken.
Inhibitions of acid secretion by E3810 and omeprazole, and their reversal by glutathione.
Suppression of acid secretion and plasma level of a once-daily dose of omeprazole
Effects of anti-acid secretory agents on various types of gastric mucus.
Hypergastrinemia after blockade of acid secretion in the rat: trophic effects.
Metabolic interactions of selected antimalarial and non-antimalarial drugs with the major pathway (3-hydroxylation) of quinine in human liver microsomes.
Relevance of antibiotic sensitivities in predicting failure of omeprazole, clarithromycin, and tinidazole to eradicate Helicobacter pylori.
Inter-relationship between serum gastrin levels, gastric mucosal histology and gastric endocrine cell growth.
The influence of gastrointestinal agents on resorption and metabolism of cyclosporine after heart transplantation: experimental and clinical results.
Inhibition of gastric acid secretion by omeprazole and ranitidine. Effects on plasma gastrin and gastric histamine, histidine decarboxylase activity and ECL cell density in normal and antrectomized rats.
Inhibition of gastric acid secretion in vivo and in vitro by an inhibitor of Cl(-)-HCO3- exchanger, 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid.
Gastric H+-K+-ATPase in situ: relation to secretory state.
Mechanism for species-specific induction of Leydig cell tumors in rats by lansoprazole.
Effects of CCK2 receptor blockade on growth parameters in gastrointestinal tract and pancreas in rats.
CagA seropositivity and the severity of Helicobacter pylori infection in dyspeptic children.
Pharmacokinetics of various single intravenous and oral doses of omeprazole.
Endoscopic assessment of blood flow in duodenal ulcers.
Active immunization against somatostatin alters regulation of gastrin in response to gastric acid secretagogues.
Mechanism of cholinergic stimulation of glucose oxidation in isolated gastric glands.
Making sense of NSAID gastropathy and considering the therapeutic options.
Endogenous gastrin stimulates regeneration of remnant pancreas after partial pancreatectomy.
Mucosal change of the stomach with low-grade mucosa-associated lymphoid tissue lymphoma after eradication of Helicobacter pylori: follow-up study of 48 cases.
Gastric mucosal histamine storing cells. Evidence for different roles of mast cells and enterochromaffin-like cells in humans.
Effect of high ionic strength and inhibitors of H,K-ATPase on the ouabain-sensitive K-p-nitrophenylphosphatase activity in the sea anemone Stichodactyla helianthus.
The cost-effectiveness of strategies to assess gastroesophageal reflux as an exacerbating factor in asthma.
The usefulness of a structured questionnaire in the assessment of symptomatic gastroesophageal reflux disease.
Proton pump inhibitors: a study of GPs' prescribing.
Effects of omeprazole, a substituted benzimidazole, on gastrointestinal secretions, serum gastrin, and gastric mucosal blood flow in dogs.
Omeprazole: inhibitor of both acid formation and translocation in gastric mucosa.
Jejunal efflux in short bowel syndrome.
Evaluation of the gastroprotective activity of cordatin, a diterpene isolated from Aparisthmium cordatum (Euphorbiaceae).
Mobilization of rat stomach ECL-cell histamine in response to short- or long-term treatment with omeprazole and/or YF 476 studied by gastric submucosal microdialysis in conscious rats.
Sucralfate affects the susceptibility of Helicobacter pylori to antimicrobial agents.
Outcomes of atypical symptoms attributed to gastroesophageal reflux treated by laparoscopic fundoplication.
Exploring an antifungal target in the plasma membrane H(+)-ATPase of fungi.
Evaluation of a proposed technique to assess unscheduled DNA synthesis and genotoxicity.
Reversal by omeprazole of the depression of gastrin cell function by fasting in the rat.
The secretory kinetics of the G cell in omeprazole-treated rats.
Omeprazole fails to alter the cytochrome P450-dependent 2-hydroxylation of estradiol in male volunteers.
Metabolic interactions of the proton-pump inhibitors lansoprazole, omeprazole and pantoprazole with other drugs.
Pharmacokinetic differences between lansoprazole enantiomers and contribution of cytochrome P450 isoforms to enantioselective metabolism of lansoprazole in dogs.
Omeprazole maintenance therapy for gastroesophageal reflux disease after failure of fundoplication.
Regression of low-grade gastric mucosa-associated lymphoid tissue lymphoma after eradication of Helicobacter pylori: possible association with p16 hypermethylation.
Short-term eradication therapy for Helicobacter pylori does not reduce the incidence of gastric metaplasia in duodenal ulcer patients.
Proton pump inhibitor therapy: preliminary results of a therapeutic interchange program.
Effects of NC-1300-B, a new benzimidazole derivative, on hog gastric H+, K+-ATPase, gastric acid secretion and HCl.ethanol-induced gastric lesions in rats.
Substituted thieno3,4-dimidazoles, a novel group of H+/K(+)-ATPase inhibitors. Differentiation of their inhibition characteristics from those of omeprazole.
A comparative study on the activity of lansoprazole, omeprazole and PD-136450 on acidified ethanol- and indomethacin-induced gastric lesions in the rat.
The role of omeprazole in the eradication of Helicobacter pylori in patients with duodenal ulcers
Proton pump inhibitors in the treatment of peptic ulcers resistant to H2-receptor antagonists
Enzyme kinetic studies on the in vitro metabolism of omeprazole by Chinese human liver microsomes
The role of thyrotropin-releasing hormone (TRH) in the pathogenesis of water-immersion stress in rats--inhibition of TRH release from the stomach by atropine, ranitidine or omeprazole.
Omeprazole may exert both a bacteriostatic and a bacteriocidal effect on the growth of Helicobacter pylori (NCTC 11637) in vitro by inhibiting bacterial urease activity.
Influences of stress on gastric alkaline secretion in rats.
Chemomechanical coupling in the gastric H,K ATPase.
Pharmacokinetic differences between lansoprazole enantiomers in rats.
Omeprazole does not enhance the metabolism of phenacetin, a marker of CYP1A2 activity, in healthy volunteers.
Effect of omeprazole in the treatment of refractory acid-related diseases in childhood: endoscopic healing and twenty-four-hour intragastric acidity.
Evidence for acid-induced transformation of omeprazole into an active inhibitor of (H+ + K+)-ATPase within the parietal cell.
Long-term omeprazole treatment suppresses body weight gain and bone mineralization in young male rats.
Effect of omeprazole treatment on feed intake and blood gastrin and pepsinogen levels in the calf.
One-day therapy for treatment of Helicobacter pylori infection.
Cost-effectiveness of treatment regimens for the eradication of Helicobacter pylori in duodenal ulcer.
Factors that may affect treatment outcome of triple Helicobacter pylori eradication therapy with omeprazole, amoxicillin, and clarithromycin.
Effect of omeprazole on gastroesophageal reflux in Barrett's esophagus.
Clarithromycin resistance, but not CYP2C-19 polymorphism, has a major impact on treatment success in 7-day treatment regimen for cure of H. pylori infection: a multiple logistic regression analysis.
The use of Smecta for the treatment of the basic digestive tract diseases
Study on omeprazole 20 mg twice weekly in prevention of duodenal ulcer relapse
Omeprazole in peptic ulceration: acid inhibition and endoscopic healing
Insulin-induced gastric ulcers in the rat.
Comparative evaluation of ulcer prevention efficacy of orally, rectally and sublingually administered omeprazole in three acute gastric ulcer models in rats.
Inhibition of H+,K+-ATPase by methyl(E)-2-(3,4-dimethoxystyryl)-benzimidazole-4-carboxylate (ALE-36).
Proton pump inhibition--the ultimate control of acid secretion?
The effect of omeprazole on ultrastructural changes in gastric parietal cells.
Secondary prevention of upper gastrointestinal bleeding associated with maintenance acid-suppressing treatment in patients with peptic ulcer bleed.
Effect of omeprazole on gastric acid secretion in man.
Identification of two main urinary metabolites of 14Comeprazole in humans.
Association of chronic urticaria with Helicobacter pylori-induced antrum gastritis
Current principles of the use of laparoscopic surgery in gastroduodenal ulcer
Effect of L-lactic acid on calcium absorption in rats fed omeprazole.
Effect of intermittent weekend therapy with omeprazole on basal and postprandial serum gastrin concentrations in patients with duodenal ulcer.
Response of MBT-2 bladder carcinoma-induced osteolysis to various agents.
pH monitoring in patients with benign voice disorders.
Visual disorders associated with omeprazole and their relation to CYP2C19 polymorphism.
Effect of 'weekend therapy' with omeprazole on basal and stimulated acid secretion and fasting plasma gastrin in duodenal ulcer patients.
Symptomatic benefit 1-3 years after H. pylori eradication in ulcer patients: impact of gastroesophageal reflux disease.
Effect of omeprazole--a gastric proton pump inhibitor--on pentagastrin stimulated acid secretion in man.
Gastrin receptor antagonist YM022 prevents hypersecretion after long-term acid suppression.
Omeprazole in the Zollinger-Ellison syndrome.
The cultured human gastric cells HGT-1 express the principal transporters involved in acid secretion.
Properties of a potassium channel in cultured human gastric cells (HGT-1) possessing specific omeprazole binding sites.
Effect of sham feeding and acute suppression of acid secretion on human gastric lipase secretion.
Omeprazole treatment of children with peptic esophagitis refractory to ranitidine therapy.
Comparison between activation of ornithine decarboxylase and histidine decarboxylase in rat stomach.
Evaluation of chromo-endoscopy for diagnosis of histological repair of gastric ulcer
High-performance liquid chromatographic determination of lansoprazole and its metabolites in human serum and urine.
Control of gastric corpus chromogranin A messenger RNA abundance in the rat.
Clinical application of gastric histology to monitor treatment of dual therapy in H. pylori eradication.
Effects of omeprazole and cimetidine on gastric acid secretion and right atrial beating frequency in isolated organ preparations from the guinea pig.
Pentadecapeptide BPC 157, cimetidine, ranitidine, bromocriptine, and atropine effect in cysteamine lesions in totally gastrectromized rats: a model for cytoprotective studies.
Gastric antisecretory activity of lansoprazole in different experimental models: comparison with omeprazole.
Endoscopic stage classification of peptic ulcer and characterization of the healing process by proton pump inhibitors
Gastric MALT lymphoma, clinical features
Prostaglandin stimulates Cl(-)-HCO3- exchange in amphibian oxynticopeptic cells.
Peak distortion in the column liquid chromatographic determination of omeprazole dissolved in borax buffer.
Ciprofloxacin-omeprazole combination therapy for eradication of Helicobacter pylori
Synthesis and anti-ulcer activity of some new compounds with arylthiomethyl-pyridine structure
Role of endothelin-1 and constitutive nitric oxide synthase in gastric mucosal resistance to indomethacin injury: effect of antiulcer agents.
Evaluation of omeprazole genotoxicity in a battery of in vitro and in vivo assays.
Stability of capsules containing omeprazole in enteric coated pellets.
Omeprazole: effective, convenient therapy for Zollinger-Ellison syndrome.
Intrahypothalamic corticotropin-releasing factor elevates gastric bicarbonate and inhibits stress ulcers in rats.
Effects of cimetidine on acute gastric mucosal injury induced by ischemia-reperfusion in rats.
Failure of oesophageal acid control in candidates for Barrett's oesophagus reversal on a very high dose of proton pump inhibitor.
Ionic dependence of adenosine uptake into cultured astrocytes.
Stimulation of electrogenic chloride secretion by prostaglandin E2 in guinea-pig isolated gastric mucosa.
High-performance thin-layer chromatographic method for the detection and determination of lansoprazole in human plasma and its use in pharmacokinetic studies.
Gastroesophageal reflux: A critical factor in pediatric subglottic stenosis.
Genetic polymorphism of CYP2C19 and lansoprazole pharmacokinetics in Japanese subjects.
DNA synthesis and genotoxicity.
Relative contributions of CYP2C9 and 2C19 to phenytoin 4-hydroxylation in vitro: inhibition by sulfaphenazole, omeprazole, and ticlopidine.
A discordance of the cytochrome P450 2C19 genotype and phenotype in patients with advanced cancer.
Activity inhibition of cytolytic lymphocytes by omeprazole.
Usefulness of every-other day administration of proton pump inhibitors from the standpoint of continuous 48-hour pH measurements-- Comparison of cimetidine, omeprazole, and lansoprazole
Effect of intermittent administration of omeprazole on serum pepsinogens in duodenal ulcer patients and healthy volunteers.
Autoradiographic demonstration of lansoprazole uptake sites in rat antrum and colon.
Sulfide and sulfoxide derivatives of substituted benzimidazoles inhibit acid formation in isolated gastric glands by different mechanisms.
Ethnic and genetic determinants of omeprazole disposition and effect.
Breath test in the diagnosis of Helicobacter pylori infection: concordance with histological methods and correlation with anatomopathological lesions of the gastric mucosa
Empirical therapy versus diagnostic tests in gastroesophageal reflux disease: a medical decision analysis.
Growth of the parathyroid glands in omeprazole-treated chickens.
Effect of omeprazole administration on pancreatic content of enzymes in rats
Nuclear uptake of the Ah (dioxin) receptor in response to omeprazole: transcriptional activation of the human CYP1A1 gene.
Effect of long-term administration of antisecretary drugs on rat gastric histamine synthesis and acid secretion--compare with omeprazole and cimetidine
Effect of short-term administration of omeprazole on serum gastrin and pepsinogens in antrectomized patients.
Cost of acid peptic disorders in a managed-care organization.
In vitro evaluation of dissolution properties and degradation products of omeprazole in enteric-coated pellets.
The influence of isolated doses of drugs, feeding and colonic bacterial ureolysis on urea breath test results.
Effects of acute administration of omeprazole or ranitidine on basal and vagally stimulated gastric acid secretion and alkalinization of the duodenum in anaesthetized cats.
Postprandial alkaline tide: does it exist?
Omeprazole, other antiulcer drugs and newly diagnosed gout.
Functional dyspepsia has a good prognosis irrespective of H. pylori status. Long-term follow-up of symptoms after anti H. pylori treatment.
Specific and dose-dependent enzyme induction by omeprazole in human beings.
Omeprazole in elderly duodenal ulcer patients: relationship between reduction in gastric acid secretion and fasting plasma gastrin.
HCO3- secretion in rat duodenum after treatment with omeprazole and ranitidine.
Gastric hyperemic response during vagally mediated acid secretion by TRH analog in rats.
In vitro activity of ebrotidine, ranitidine, omeprazole, lansoprazole, and bismuth citrate against clinical isolates of Helicobacter pylori.
Will Helicobacter pylori affect short-term rebleeding rate in peptic ulcer bleeding patients after successful endoscopic therapy?
CYP2C19 genotype related effect of omeprazole on intragastric pH and antimicrobial stability.
Mechanisms of stimulatory effect of neuromedin C on pancreatic exocrine secretion in conscious rats.
Effect of omeprazole on eicosanoid formation in and release from guinea-pig gastric mucosal cells.
Demonstration of the electrogenicity of proton translocation during the phosphorylation step in gastric H+K(+)-ATPase.
Membrane potential changes after infection of monocytes by Toxoplasma gondii.
Gastric endocrine cells and gastritis in patients receiving long-term omeprazole treatment.
Evidence that gastrin enhances 45Ca uptake into bone through release of a gastric hormone.
Gastric acid-independent enhancement of exocrine pancreatic secretion by dietary protein in chronic bile-pancreatic juice diverted rats.
Plasma gastrin and gastric enterochromaffinlike cell activation and proliferation. Studies with omeprazole and ranitidine in intact and antrectomized rats.
Proliferation of enterochromaffinlike cells in omeprazole-treated hypergastrinemic rats.
A new method for evaluating gastric ulcer healing by endoscopic ultrasonography.
The effect of omeprazole on gastric emptying in patients with duodenal ulcer disease.
The effect of omeprazole on gastric juice viscosity, pH and bacterial counts.
Laryngeal manifestations of gastroesophageal reflux before and after treatment with omeprazole.
Gastrin does not stimulate growth of the rat pancreas.
Characterization of Syrian hamster gastric mucosal H+,K+-ATPase.
Chronic gastric ulcer healing in rats subjected to selective and non-selective cyclooxygenase-2 inhibitors.
Development of a health-related quality-of-life questionnaire for individuals with gastroesophageal reflux disease: a validation study.
Properties of light and heavy vesicles simultaneously prepared from hog gastric mucosae.
Antisecretory and antiulcer effect of T-330, a novel reversible proton pump inhibitor, in rats.
Interaction between Helicobacter pylori and human gastric epithelial cells in culture: effect of antiulcer drugs.
Peptic ulcer and Helicobacter pylori. Comments on the authors' cases
Effect of curing Helicobacter pylori infection on intragastric pH during treatment with omeprazole.
Critical effect of Helicobacter pylori infection on the effectiveness of omeprazole for prevention of gastric or duodenal ulcers among chronic NSAID users.
Decision analysis of Helicobacter pylori eradication therapy using omeprazole with either clarithromycin or amoxicillin.
Lansoprazole reverses Helicobacter pylori-inhibited gastric epithelial cell growth.
Potentiation of hypericin and hypocrellin-induced phototoxicity by omeprazole.
Gastric metaplasia and Helicobacter pylori.
Activity of omeprazole on Helicobacter pylori and relation to toxicity of strains.
Metronidazole, omeprazole and clarithromycin: an effective combination therapy for Helicobacter pylori infection.
Helicobacter pylori eradication therapy for high-grade mucosa-associated lymphoid tissue lymphomas of the stomach with analysis of p53 and K-ras alteration and microsatellite instability.
High eradication rates in Helicobacter pylori infection in patients with duodenal ulcer who failed previous eradication therapy
Etiological involvement of Helicobacter pylori in "reflux" gastritis after gastrectomy.
Pharmacological therapy of Helicobacter pylori infection.
Simultaneous high-performance liquid chromatographic analysis of omeprazole and its sulphone and sulphide metabolites in human plasma and urine.
Nonlinear kinetics after high-dose omeprazole caused by saturation of genetically variable CYP2C19.
Proton pump inhibitors or histamine-2 receptor antagonists for the prevention of recurrences of erosive reflux esophagitis: a cost-effectiveness analysis.
Cytoprotective action of histamine against 0.6 N HCl-induced gastric mucosal injury in rats; comparative study with adaptive cytoprotection induced by exogenous acid.
Turnover of the gastric H+,K(+)-adenosine triphosphatase alpha subunit and its effect on inhibition of rat gastric acid secretion.
Regulation of peptide YY homeostasis by gastric acid and gastrin.
Lansoprazole and omeprazole have similar effects on plasma gastrin levels, enterochromaffin-like cells, gastrin cells and somatostatin cells in the rat stomach.
Helicobacter pylori eradication in the African setting, with special reference to reinfection and duodenal ulcer recurrence.
Disulfide cross-linking of H,K-ATPase opens Cl- conductance, triggering proton uptake in gastric vesicles. Studies with specific inhibitors.
Influence of acid and angiogenesis on kinetics of gastric ulcer healing in rats: interaction with indomethacin.
Omeprazole versus histamine H2 receptor antagonists in the treatment of acute upper non-variceal bleeding.
Effect of lansoprazole on human leukocyte function.
Enantioselective hydroxylation of omeprazole catalyzed by CYP2C19 in Swedish white subjects.
Effects of long-term hypergastrinaemia on the ultrastructure of enterochromaffin-like cells in the stomach of the rat, hamster and guinea pig.
Omeprazole-induced hypergastrinemia does not influence growth of colon carcinoma.
Gastric acid and pepsin hypersecretion in conscious rabbits.
Tritiated thymidine incorporation into DNA in rat gastric mucosal cells.
Peptic ulcer: changing indications for gastric resection during the last 15 years
Helicobacter pylori eradication in clinical practice: one-week low-dose triple therapy is preferable to classical bismuth based triple therapy.
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