Drugs online research references
J Antimicrob Chemother. 1985 May;15(5):587-95.
Studies in vivo on the killing rate and refractory period of penicillin V in an experimental streptococcal infection.
Roos K, Brorson JE, Holm SE.
The refractory period and the killing rate of beta-haemolytic streptococci after exposure to phenoxymethylpenicillin were tested in an in-vivo model. beta-Haemolytic streptococci were injected into steel net chambers implanted subcutaneously on the backs of rabbits. The rabbits were treated with infusions of phenoxymethylpenicillin, either as a single dose to measure the refractory period or as repeated doses in order to measure the killing rate of streptococci. The peak concentration of phenoxymethylpenicillin in tissue chamber fluid occurred about 16-120 min post infusion, and reached 0.4 mg/l in infected and 0.6 mg/l in uninfected tissue cage fluid. In the tissue cage fluid the phenoxymethylpenicillin concentration exceeded 0.03 mg/l, the MIC-value for the streptococcal strain used, for at least 6 h. After a single infusion there was a decline in viable count. The bacteria did not reach their original numbers until 60-70 h later. After the sixth infusion streptococci were no longer detectable in tissue cage fluid. There was a close correlation between viable counts before treatment and the time required for eradication of bacteria. L-phase variants of beta-haemolytic streptococci were not found when tissue cage fluid was plated on special media.
online pharmacy ref source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3924881&dopt=Abstract
Ann Otol Rhinol Laryngol. 1985 May-Jun;94(3):278-80.
Impact of phenoxymethylpenicillin and clindamycin on microflora in recurrent tonsillitis.
Tuner K, Nord CE.
A total of 75 patients with recurrent tonsillitis, between 15 and 44 years of age, were divided into three groups, two of which were treated with antibiotics before surgery. Bacteriological specimens were collected before treatment started and the microflora of the excised tonsils were analyzed. Bacteroides species were found in the tonsils of 83% of the patients, and 50% of these microorganisms were beta-lactamase producers. Other bacteria found were Staphylococcus aureus in 45%, beta-streptococci group A in 4%, and beta-streptococci groups C and G in 24%. Hemophilus species were isolated from 50%, but no strains produced beta-lactamase. Fusobacteria were recovered from 41%; one strain produced beta-lactamase. After administration of phenoxymethylpenicillin in doses of 1 g twice a day for nine days, the beta-streptococci were eliminated, but no change of the amount of S aureus, Hemophilus, Bacteroides, or fusobacteria was seen. Clindamycin in doses of 0.15 g four times daily for nine days diminished almost all bacteria except for the Hemophilus species.
online pharmacy ref source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3925864&dopt=Abstract
Pharmacology. 1985;31(2):115-20.
Absorption of oral penicillin before and after gastroplasty for morbid obesity.
Miskowiak J, Andersen B, Nielsen VG.
Gastroplasty for morbid obesity results in a small proximal pouch with a narrow stoma to the distal stomach. Absorption of phenoxymethylpenicillin given in tablets and liquid form was evaluated in 8 females before and 3 months after gastroplasty. Penicillin absorption was not affected to any significant extent. Oral penicillin can therefore safely be given for the treatment of infections in patients after gastroplasty.
online pharmacy ref source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3927327&dopt=Abstract
Herbs and Pharmaceuticals Online ||
Hair Million herbal formula for hair loss and hair growth ||
Wellstreet online pharmacy for click-order prescription medications ||
Altace Online Pharmacy ||
Rx Drugs USA, Prescription Drugs Online Pharmacy ||
Insurance plans and information ||
Insurance policies for all purposes ||
Antibiotics and prescription medications online literature ||