Drugs online research references
J Intellect Disabil Res. 1998 Aug;42 ( Pt 4):301-6.
Selective serotonin re-uptake inhibitors for the treatment of perseverative and maladaptive behaviours of people with intellectual disability.
Branford D, Bhaumik S, Naik B.
Southern Derbyshire Mental Health Trust, Derby, England.
A retrospective case-note analysis was undertaken of 37 adults with intellectual disability who lived in Leicestershire, England. The subjects were prescribed one of two selective serotonin re-uptake inhibitor (SSRI) antidepressants, i.e. fluoxetine or paroxetine, for perseverative and maladaptive behaviours. The SSRIs proved to be of no benefit for 15 subjects (40%) and led to a deterioration in a further nine cases (25%). However, some reduction of perseverative and maladaptive behaviours was achieved in 13 cases (35%). There was no difference in the responses to fluoxetine or paroxetine.
online pharmacy ref source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9786445&dopt=Abstract
note: kwd match paxil online literature
J Clin Psychol. 1999 Jan;55(1):129-33.
Trends in the use of selective serotonin reuptake inhibitors in nine Department of Veterans Affairs outpatient facilities.
Voris JC.
University of South Carolina, College of Pharmacy, Dorn Veterans Hospital, Columbia 29209-1639, USA.
The average daily dose and need for dose escalations for the drugs known as selective serotonin reuptake inhibitors (SSRIs) has frequently been a point of controversy. This study reports on the information gathered from nine Veterans Affairs hospitals over a two six-month periods. Average daily doses of fluoxetine, paroxetine, and sertraline started at 30.9 mg, 24.2 mg, and 87.8 mg and ended at 28.4 mg, 24.2 mg, and 89.8 mg, respectively. Cost, number of prescriptions, and dosage strength data is also presented.
online pharmacy ref source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10100839&dopt=Abstract
note: kwd match paxil online literature
md.tsukuba.ac.jp
Phencyclidine (PCP) is known to be an inhibitor of serotonin (5-HT) uptake and to increase serotonergic activity. The development of tolerance to serotonergic stereotyped behaviors induced by repeated PCP treatment and changes of 5-HT transporters were examined. Backpedalling was significantly reduced in frequency following 14 days PCP treatment (7.5 mg/kg per day). Furthermore, repeated PCP treatment decreased the equilibrium dissociation constant (Kd) of [3H]paroxetine binding to 5-HT transporters in whole brain excluding the cerebellum without any change of maximum number of binding sites (Bmax). Single treatment with PCP failed to change binding parameters. These results indicate that repeated PCP treatment causes tolerance in serotonergic stereotyped behavior and increases affinity of 5-HT transporters for [3H]paroxetine binding. The increased affinity of 5-HT transporters could represent compensatory responses to chronic inhibition of 5-HT uptake by PCP.
online pharmacy ref source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10696810&dopt=Abstract
note: kwd match paxil online literature
Herbs and Pharmaceuticals Online ||
Hair Million herbal formula for hair loss and hair growth ||
Antibiotics and prescription medications online literature ||