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  • Effect of cyclodextrin charge on complexation of neutral and charged substrates: comparison of (SBE)7M-beta-CD to HP-beta-CD.
  • A possible mechanism of naproxen-induced lipid peroxidation in rat liver microsomes.
  • Nonsteroidal anti-inflammatory drugs in early pregnancy.
  • Disposition of naproxen, naproxen acyl glucuronide and its rearrangement isomers in the isolated perfused rat liver.
  • Enantiomeric separation of R,S-naproxen by conventional and nano-liquid chromatography with methyl-beta-cyclodextrin as a mobile phase additive.
  • Iatrogenic cost factors incorporating mild and moderate adverse events in the economic comparison of aceclofenac and other NSAIDs.
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  • Acute gastrointestinal permeability responses to different non-steroidal anti-inflammatory drugs.
  • Nonsteroidal antiinflammatory drugs and gastrointestinal hospitalizations in Saskatchewan: a cohort study.
  • Tegumental alterations in Schistosoma mansoni worms induced by treatment of infected mice with naproxen pre- and/or post-infection.
  • Renal prostaglandins and natriuretic action of oxytocin and vasopressin in rats.
  • Three new vanadyl(IV) complexes with non-steroidal anti-inflammatory drugs (Ibuprofen, Naproxen and Tolmetin). Bioactivity on osteoblast-like cells in culture.
  • Activation of peroxisome proliferator-activated receptor isoforms and inhibition of prostaglandin H(2) synthases by ibuprofen, naproxen, and indomethacin.
  • Effects of paracetamol and naproxen on pain syndromes of various genesis
  • The use and effect of analgesics in patients who regularly drink alcohol.
  • Design and evaluation of osmotic pump tablets of naproxen sodium.
  • Effects of anti-inflammatory drugs on the arachidonic acid induced erythema in guinea pigs
  • Prostaglandin biosynthesis by fat body from larvae of the beetle Zophobas atratus.
  • Drug switching patterns among patients taking non-steroidal anti-inflammatory drugs: a retrospective cohort study of a general practitioners database in the United Kingdom.
  • Mechanism for further enhancement in drug dissolution from solid-dispersion granules upon storage.
  • Synovial Tissue, Synovial Fluid, and Plasma Distribution of Nonsteroidal Anti-inflammatory Drugs: Clinical Implications.
  • Pharmacology of the potent new non-steroidal anti-inflammatory agent aceclofenac.
  • Modulation of the Expression of Glucocorticoid Receptors in Synovial Fibroblasts and Chondrocytes by Prostaglandins and NSAIDs.
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  • Controlled-release naproxen using micronized ethyl cellulose by wet-granulation and solid-dispersion method.
  • Characterization, quantification, and bioactivities of anthocyanins in Cornus species.
  • Enantioselective hydrolysis of naproxen ethyl ester catalyzed by monoclonal antibodies.
  • A validated LC method for the determination of clopidogrel in pharmaceutical preparations.
  • Protection by zinc acexamate against gastric lesions induced by non-steroid anti-inflammatory agents
  • Trends in medication use for osteoarthritis treatment.
  • Effect of combined chemotherapy and anti-inflammatory drugs on murine schistosomiasis.
  • Analysis of acidic drugs in the effluents of sewage treatment plants using liquid chromatography-electrospray ionization tandem mass spectrometry.
  • Late phase of nitroglycerin-induced coronary vasodilatation blunted by inhibition of prostaglandin synthesis.
  • The cyclo-oxygenase-2 inhibitor celecoxib perturbs intracellular calcium by inhibiting endoplasmic reticulum Ca2+-ATPases: a plausible link with its anti-tumour effect and cardiovascular risks.
  • Modulatory role of cyclooxygenase inhibitors in aging- and scopolamine or lipopolysaccharide-induced cognitive dysfunction in mice.
  • Integration of reactive membrane extraction with lipase-hydrolysis dynamic kinetic resolution of naproxen 2,2,2-trifluoroethyl thioester in isooctane.
  • Prevention by parenteral aspirin of indomethacin-induced gastric lesions in rats: mediation by salicylic acid.
  • The effects of anti-inflammatory and other agents on the rat dermal arthus reaction.
  • Antimicrobial action of Nitens mouthwash (cetyltrimethylammonium naproxenate) on multiple isolates of pharyngeal microbes: a controlled study against chlorhexidine, benzydamine, hexetidine, amoxicillin, amoxicillin-clavulanate, clarithromycin, and cefaclor.
  • Naproxen ion-selective electrode and its application to pharmaceutical analysis.
  • Intercalation and controlled release of pharmaceutically active compounds from a layered double hydroxide.
  • Modulation of NSAID-induced antinociceptive and anti-inflammatory effects by alpha2-adrenoceptor agonists with gastroprotective effects.
  • Prevention of iron deficiency anemia in IUD users by prostaglandin synthetase inhibitors.
  • Antioxidation theory of non-steroidal anti-inflammatory drugs based upon the inhibition of luminol-enhanced chemiluminescence from the myeloperoxidase reaction.
  • Differential effects of cyclooxygenase inhibitors on haloperidol-induced catalepsy.
  • Efficient synthesis of alpha-aryl esters by room-temperature palladium-catalyzed coupling of aryl halides with ester enolates.
  • Effect of nabumetone (BRL 14777), a new anti-inflammatory drug, on human platelet reactivity ex vivo: comparison with naproxen.
  • Interactions of human organic anion transporters and human organic cation transporters with nonsteroidal anti-inflammatory drugs.
  • Intracranial complications of preinjury anticoagulation in trauma patients with head injury.
  • Gabapentin and pregabalin can interact synergistically with naproxen to produce antihyperalgesia.
  • Cost of heart failure among hypertensive users of nonspecific NSAIDs and COX-2-specific inhibitors.
  • Hydrogen bonding with adsorbent during storage governs drug dissolution from solid-dispersion granules.
  • Dramatically synergetic effect of carboxylic acid additive on tridentate titanium catalyzed enantioselective hetero-diels-alder reaction: additive acceleration and nonlinear effect.
  • Capillary electrochromatographic separation of non-steroidal anti-inflammatory drugs with a histidine bonded phase.
  • The activity of non-steroidal anti-inflammatory drugs in the rat mesenteric vasculature.
  • Chiral separation of naproxen and flurbiprofen by capillary electrophoresis
  • Determination of acidic drugs in sewage water by gas chromatography-mass spectrometry as tert.-butyldimethylsilyl derivatives.
  • Effect of PVP K-25 on the formation of the naproxen:beta-ciclodextrin complex.
  • In vitro detection of (S)-naproxen and ibuprofen binding to plaques in the Alzheimer's brain using the positron emission tomography molecular imaging probe 2-(1-6-(2-(18)Ffluoroethyl)(methyl)amino-2-naphthylethylidene)malononitrile.
  • N-in-one permeability studies of heterogeneous sets of compounds across Caco-2 cell monolayers.
  • Reintroduction of anti-inflammatory drug therapy after drug-associated gastro-intestinal disturbances.
  • Search of antimicrobial activity of selected non-antibiotic drugs.
  • The analgesic and anti-inflammatory profile of (+/-)-5-benzoyl-1,2-dihydro-3H-pyrrolo1,2apyrrole-1-carboxylic acid (RS-37619).
  • Synthesis and antimicrobial activities of some isocoumarin and dihydroisocoumarin derivatives.
  • Piroxicam, a novel anti-inflammatory agent.
  • The influence of non-steroidal anti-inflammatory and antithyroid agents on myeloperoxidase-catalysed activities of human leucocytes.
  • Albumin binding of anti-inflammatory drugs. Utility of a site-oriented versus a stoichiometric analysis.
  • Renal papillary necrosis induced by naproxen.
  • Effects of antiinflammatory drugs on arthritic cartilage: a high-frequency quantitative ultrasound study in rats.
  • Medical therapy for menstrual migraine
  • Rofecoxib in rheumatoid arthritis: new indication. No better that other NSAIDS.
  • Zinc-naproxen complex: synthesis, physicochemical and biological evaluation.
  • Microbial transformations of S-naproxen by Aspergillus niger ATCC 9142.
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  • Inhibition of proliferation of human cancer cells and cyclooxygenase enzymes by anthocyanidins and catechins.
  • Effect of nonsteroid anti-inflammatory drugs on subarachnoid hemorrhage in dogs.
  • Osteoarthritis and non-steroidal and anti-inflammatory drugs: a multi-centre comparative study.
  • Exacerbation of experimental colitis by nonsteroidal anti-inflammatory drugs is not related to elevated leukotriene B4 synthesis.
  • Inhibition of cyclooxygenase (COX) enzymes by compounds from Daucus carota L. Seeds.
  • Synthesis, characterization, and antiinflammatory activity of naproxen complexes with rare earth (III).
  • Elimination of COD, microorganisms and pharmaceuticals from sewage by trickling through sandy soil below leaking sewers.
  • Effect of nonsteroidal antiinflammatory drugs on the neutrophil promoted inactivation of alpha-1-proteinase inhibitor.
  • Strategic selection of hyperthermophilic esterases for resolution of 2-arylpropionic esters.
  • HPLC determination of naproxen in plasma.
  • A water-insoluble drug monolithic osmotic tablet system utilizing gum arabic as an osmotic, suspending and expanding agent.
  • Supercritical fluid generated stationary phases for liquid chromatography and capillary electrochromatography.
  • Thermodynamics of solutions IV: solvation of ketoprofen in comparison with other NSAIDs.
  • Inhibitory effects of nonsteroidal anti-inflammatory drugs (NSAIDs) on the metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in mouse lung explants.
  • Weight bearing as a measure of disease progression and efficacy of anti-inflammatory compounds in a model of monosodium iodoacetate-induced osteoarthritis.
  • Acute phase response in patients undergoing lumbar spinal surgery: modulation by perioperative treatment with naproxen and famotidine.
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  • 2-Dialkylamino-6-acylmalononitrile substituted naphthalenes (DDNP analogs): novel diagnostic and therapeutic tools in Alzheimer's disease.
  • Pharmacologic suppression of neuronal oxidative damage and dendritic degeneration following direct activation of glial innate immunity in mouse cerebrum.
  • Naproxen affects Ca(2+) fluxes in mitochondria, microsomes and plasma membrane vesicles.
  • Determination of acidic pharmaceuticals, antibiotics and ivermectin in river sediment using liquid chromatography-tandem mass spectrometry.
  • Cooperation between Aspirin-triggered lipoxin and nitric oxide (NO) mediates anti-adhesive properties of NCX-4016 (NO-aspirin) on neutrophil-endothelial cell adherence.
  • Is it possible to rate digestive toxicities of NSAIDs?
  • The effect of a novel, non-steroidal anti-inflammatory compound, nabumetone (BRL 14777), on cellular infiltration into 24-hour polyvinyl sponge implants in the rat, compared with some steroidal and non-steroidal anti-inflammatory drugs.
  • Comparative effects of drugs on four paw oedema models in the rat.
  • The Arthus reaction in rats, a possible test for anti-inflammatory and antiheumatic drugs.
  • Management of IUD-associated menorrhagia in female rhesus monkeys (Macaca mulatta).
  • Determination of antinociceptive efficacy of drugs in mice using different water temperatures in a tail-immersion test.
  • New prostaglandin synthetase inhibitors--di-and triphenylacrylonitriles.
  • Measurement of drug use in a defined population. Evaluation of the defined daily dose (DDD) methodology.
  • Macromolecular prodrugs. XV. Colon-targeted delivery--bioavailability of naproxen from orally administered dextran-naproxen ester prodrugs varying in molecular size in the pig.
  • Effect of non-steroidal anti-inflammatory drugs on glutathione levels in various organs of rat.
  • Effect of cytoprotective and antiulcer drugs on the healing process of subacute gastric ulcer in rat (a new model).
  • Effects of interleukin-1 and anti-inflammatory drugs on the degradation of human articular cartilage.
  • Elevation of prostaglandin and cyclic AMP levels by arachidonic acid in primary epithelial cell cultures of C3H mouse mammary tumors.
  • Analgetic activity of SK&F 105809, a dual inhibitor of arachidonic acid metabolism.
  • Regulation of ADH-stimulated water flow at a post-luminal barrier in toad bladder.
  • Binding of nonsteroidal anti-inflammatory agents and their effect on binding of racemic warfarin and its enantiomers to human serum albumin.
  • Effect of cytokines and anti-arthritic drugs on glycosaminoglycan synthesis by bovine articular chondrocytes.
  • Adult-onset Still's disease; clinical and laboratory features, treatment and progress of 45 cases.
  • Naproxen pharmacokinetics in patients with rheumatoid arthritis during active polyarticular inflammation.
  • Synthesis and pharmacologic study of new esters of naproxen with derivatives of N-oxyethylpiperazine
  • Evaluation of the effects of various anti-arthritic drugs on type II collagen-induced mouse arthritis model.
  • Pharmacokinetics of naproxen in healthy volunteers and in patients with diabetic microangiopathy.
  • Effects of nonsteroidal anti-inflammatory drugs on rat gastric mucosal phosphodiesterase activity.
  • Naproxen pharmacokinetics in the elderly.
  • Studies on organ weights in naproxen treated rats after intermittent exposure to simulated high altitude.
  • Interaction of naproxen with cholestyramine.
  • Anovulatory luteal cycles in primates.
  • Prostaglandin inhibition and central corneal thickness after cataract extraction.
  • Pharmacokinetics of naproxen in patients with hypoproteinemia.
  • Effective of acetylsalicylic acid, indomethacin, phenylbutazone, paracetamol, ibuprofen and naproxen on canine gastric mucosa: a histological and ultrastructural study.
  • Nabumetone. A reappraisal of its pharmacology and therapeutic use in rheumatic diseases.
  • Oxidative stress in isolated rat hepatocytes during naproxen metabolism.
  • In vitro effects of 2 antirheumatic drugs on the synthesis and expression of proinflammatory cytokines in synovial membranes from patients with rheumatoid arthritis.
  • The pharmacologic effects of 5-3,5-bis(1,1-dimethylethyl)-4- hydroxyphenyl-1,3,4-thiadiazole-2(3H)-thione, choline salt (CI-986), a novel inhibitor of arachidonic acid metabolism in models of inflammation, analgesia and gastric irritation.
  • Effects of codeine, naproxen and dexamethasone on formalin-induced pain in the naked mole-rat.
  • Effects of indomethacin and naproxen on renal p-amino-hippurate (PAH) excretion in rats during postnatal development.
  • Effects of acetylsalicylic acid (aspirin) and naproxen sodium (naproxen) on ovulation, prostaglandin, and progesterone production in the rabbit.
  • Platelet-activating factor production in stimulated macrophages is down-regulated by concurrently produced prostaglandin E2.
  • Control of poorly soluble drug dissolution in conditions simulating the gastrointestinal tract flow. 1. Effect of tablet geometry in buffered medium.
  • Naproxen, a 'specific" antirheumatic drug?
  • Human whole blood assays for inhibition of prostaglandin G/H synthases-1 and -2 using A23187 and lipopolysaccharide stimulation of thromboxane B2 production.
  • Second-derivative synchronous fluorescence spectroscopy for the simultaneous determination of naproxen and salicylic acid in human serum.
  • Anti-inflammatory activity of polyphosphazene-based naproxen slow-release systems.
  • Cost considerations in headache treatment. Part 2: Acute migraine treatment.
  • Cytochromes P450, 1A2, and 2C9 are responsible for the human hepatic O-demethylation of R- and S-naproxen.
  • IPDAS: a novel technology brings new benefits when applied to naproxen sodium.
  • O-methyl 14Cnaproxen O-demethylase activity in human liver microsomes: evidence for the involvement of cytochrome P4501A2 and P4502C9/10.
  • Cytokine-induced inhibition of bone matrix proteins is not mediated by prostaglandins.
  • Cross-reactions in patch testing and photopatch testing with ketoprofen, thiaprophenic acid, and cinnamic aldehyde.
  • Detection of naproxen-induced intestinal permeability change may be facilitated by adding a standardized meal but not by forming marker ratios.
  • Experimental analysis of progressive necrosis after spinal cord trauma in the rat: etiological role of the inflammatory response.
  • Activation of cytoprotective prostaglandin synthase-1 by minoxidil as a possible explanation for its hair growth-stimulating effect.
  • Nonsteroidal anti-inflammatory drugs as scaffolds for the design of 5-lipoxygenase inhibitors.
  • Prostaglandin biosynthesis by salivary glands isolated from the lone star tick, Amblyomma americanum.
  • Cystitis and nonsteroidal antiinflammatory drugs: an incidental association or an adverse effect?
  • Strain tendinitis--short-term treatment with antiphlogistics. Experiences from a four-day march in Nijmegen 1996
  • The antinociceptive effect of tramal when combined with nonsteroidal anti-inflammatory preparations
  • Non-competitive inhibition of GABAA responses by a new class of quinolones and non-steroidal anti-inflammatories in dissociated frog sensory neurones.
  • Simultaneous analysis of several non-steroidal anti-inflammatory drugs in human urine by high-performance liquid chromatography with normal solid-phase extraction.
  • Histamine H2-receptor antagonist action of ebrotidine. Effects on gastric acid secretion, gastrin levels and NSAID-induced gastrotoxicity in the rat.
  • Endothelin-1 stimulates the release of arachidonic acid and prostaglandins in cultured human ciliary muscle cells: activation of phospholipase A2.
  • Effects of the combined oral administration of NSAIDs and dextromethorphan on behavioral symptoms indicative of arthritic pain in rats.
  • Regional intestinal permeability in rats of compounds with different physicochemical properties and transport mechanisms.
  • Effects of tenidap and nonsteroidal antiinflammatory drugs on the response of cultured human T cells to interleukin 2 in rheumatoid arthritis.
  • Interaction of cyclosporine A and nonsteroidal anti-inflammatory drugs on renal function in patients with rheumatoid arthritis.
  • Pharmacokinetic and local tissue disposition studies of naproxen-following topical and systemic administration in dogs and rats.
  • Ibuprofen inhibits rat brain deamidation of anandamide at pharmacologically relevant concentrations. Mode of inhibition and structure-activity relationship.
  • Toxicokinetics of indomethacin-induced intestinal permeability in the rat.
  • Pharmacokinetic evaluation of conventional and controlled-release product of naproxen.
  • Light induces peroxidation in retina by activating prostaglandin G/H synthase.
  • 99mTcdiphosphonate uptake and hemodynamics in experimental arthritis: effect of naproxen in the canine carrageenan injection model.
  • Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis.
  • Effects of anti-inflammatory agents and some other drugs on prostaglandin biotransport.
  • Staphylococcal septic arthritis: antibiotic and nonsteroidal anti-inflammatory drug treatment in a rabbit model.
  • Evaluation of atypical cytochrome P450 kinetics with two-substrate models: evidence that multiple substrates can simultaneously bind to cytochrome P450 active sites.
  • Gastrointestinal tract bleeding associated with naproxen sodium vs ibuprofen.
  • Effect of a nitric oxide-releasing naproxen derivative on hypertension and gastric damage induced by chronic nitric oxide inhibition in the rat.
  • Glutathione disulfide formation during naproxen metabolism in the isolated rat hepatocytes.
  • Development of an HPLC assay to study the effect of endogenous and exogenous substances on heat-induced aggregation of human serum albumin.
  • The inhibitory activities of 480156-S and its related compounds on prostaglandin synthetase
  • Determination of the end-point of naproxen sodium granules in Glatt VG-WS-CD high-shear granulator fluid bed dryer equipment
  • Cyclooxygenase-1 and cyclooxygenase-2 selectivity of widely used nonsteroidal anti-inflammatory drugs.
  • Photocontact dermatitis from ketoprofen and tiaprofenic acid: cross-reactivity study in 12 consecutive patients.
  • Tumor fever in patients with nasopharyngeal carcinoma: clinical experience of 67 patients.
  • Effect of PEG 4000 on the dissolution rate of naproxen.
  • Rational use of non-steroidal anti-inflammatory drugs in primary care
  • Naproxen incorporated lipid emulsions. I. Formulation and stability studies.
  • Renal targeting of a non-steroidal anti-inflammatory drug: effects on renal prostaglandin synthesis in the rat.
  • Determination of naproxen with chemiluminescence detection.
  • Enhancement of chemotherapeutic drug toxicity to human tumour cells in vitro by a subset of non-steroidal anti-inflammatory drugs (NSAIDs).
  • Effects of trifluoperazine and verapamil on the hydro-osmotic response to antidiuretic hormone in the urinary bladder of the toad.
  • Diacerhein and rhein reduce the interleukin 1beta stimulated inducible nitric oxide synthesis level and activity while stimulating cyclooxygenase-2 synthesis in human osteoarthritic chondrocytes.
  • Effect of chemical structure on the release of certain propionic acid derivatives from their dosage forms.
  • Effects of acetylsalicylic acid and naproxen on the mechanical and biochemical properties of intact skin in rats.
  • Enhancement of phosphorylation and transcriptional activity of the glucocorticoid receptor in human synovial fibroblasts by nimesulide, a preferential cyclooxygenase 2 inhibitor.
  • The role of prostaglandins in the bradykinin-induced activation of serosal afferents of the rat jejunum in vitro.
  • Esters of naproxen as potential prodrugs for skin penetration. 1. Synthesis and physico-chemical properties
  • Involvement of drug-derived peroxides in the phototoxicity of naproxen and tiaprofenic acid.
  • Diffusion of naproxen in presence of beta-cyclodextrin across a silicone rubber membrane.
  • Modification of proinflammatory cytokine production by the antirheumatic agents tenidap and naproxen. A possible correlate with clinical acute phase response.
  • Effects of inhibition of prostaglandin synthesis on uterine oxytocin receptor concentration and myometrial gap junction density in parturient rats.
  • Transcriptional regulation of plasminogen activator inhibitor-1 expression in human synovial fibroblasts by prostaglandin E2: mediation by protein kinase A and role of interleukin-1.
  • The effect of a prostaglandin synthetase inhibitor on the hormonal profile and the endometrium in women.
  • The effect of the prostaglandin-inhibitor naproxen on the endothelial cell-loss after cataract extraction.
  • In vivo evidence for prostaglandin inhibitory activity in New Zealand green-lipped mussel extract.
  • The effect of reported prostaglandin synthetase inhibitors on estradiol-stimulated uterine prostaglandin biosynthesis in vivo in the ovariectomized rat.
  • Interactions with the protein binding of 7-hydroxy-methotrexate in human serum in vitro.
  • Low molecular weight proteins as carriers for renal drug targeting: naproxen coupled to lysozyme via the spacer L-lactic acid.
  • Influence of prostaglandin precursors and synthesis inhibitors in vascular bed perfused without a pump.
  • The response to arachidonic acid before and after non-steroidal anti-inflammatory drugs in normotensive and hypertensive rats.
  • Effect of oxygen free radical products on rabbit iris vascular permeability.
  • Myometrial oxytocin receptors and prostaglandin in the parturition process in the rat.
  • Plasma and tissue kinetics of phenylbutazone and naproxen in dogs.
  • Interim report: National Registry of Possible Drug-Induced Ocular Side Effects.
  • Effects of ketoprofen on release of prostaglandin F2 alpha from uterus of rat in perinatal period.
  • Indomethacin/ibuprofen-like anti-inflammatory agents selectively potentiate the gamma-aminobutyric acid-antagonistic effects of several norfloxacin-like quinolone antibacterial agents on 35St-butylbicyclophosphorothionate binding.
  • Cross-sectional study of rheumatoid arthritis treatment in a university hospital.
  • Improved cost-effectiveness ratio with a patient self-adjusted naproxen dosing regimen in osteoarthritis treatment.
  • Serum concentrations of salicylate and naproxen during concurrent therapy in patients with rheumatoid arthritis.
  • Effect of naproxen on the semiconservative DNA synthesis and DNA repair of various cell systems
  • Bradykinin modulates mucin secretion but not synthesis from an intestinal goblet cell line.
  • Pharmacokinetics of single-dose administration of naproxen at 10:00 and 22:00 hours.
  • The pharmacology of arachidonic acid-induced rat paw edema.
  • Pharmacologic manipulation of a four day murine delayed type hypersensitivity model.
  • Determination of naproxen and its desmethyl metabolite in human plasma or serum by high performance liquid chromatography.
  • Lipoxygenase products of arachidonic acid modulate biosynthesis of platelet-activating factor (1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) by human neutrophils via phospholipase A2.
  • Second-derivative spectrophotometric determination of naproxen in the presence of its metabolite in human plasma.
  • Inhibition of prostaglandin synthesis in rat kidney perfused with and without erythrocytes: implication for analgesic nephropathy.
  • Penetration of naproxen and salicylate into inflammatory exudates in the rat.
  • Effect of naproxen on the steady-state serum concentration and anticoagulant activity of warfarin.
  • Synthesis and structure-activity relationships of anti-inflammatory 9,10-dihydro-9-oxo-2-acridine-alkanoic acids and 4-(2-carboxyphenyl)aminobenzenealkanoic acids.
  • Inhibition of aryl sulfotransferase by carboxylic acids.
  • Modulation of the membrane surrounding particulate cement and polyethylene in the rabbit tibia.
  • Naproxen kinetics in synovial fluid of patients with osteoarthritis.
  • Inhibition of prostanoid synthesis by human gastric mucosa.
  • Effects of instrumentation on myometrial activity in the oophorectomized ewe.
  • Effect of naproxen on DNA synthesis and DNA repair of human lymphocytes in in vivo experiments
  • Putative active site template model for cytochrome P4502C9 (tolbutamide hydroxylase).
  • Endoscopic evaluation of the effects of diacerhein and naproxen on the gastroduodenal mucosa
  • Clinical pharmacology and therapeutic uses of non-steroidal anti-inflammatory drugs in the horse.
  • In vivo murine studies on the biochemical mechanism of acetaminophen cataractogenicity.
  • Comparative evaluation of the efficacy of naproxen sodium and ibuprofen in the treatment of primary dysmenorrhea
  • Treatment of juvenile arthritis.
  • The effect of Voltaren on the gastrointestinal excretion of blood
  • The influence of retinol, tocopherol and cimetidine on the ulcerogenic effect of Orthofen, indomethacin and naproxen
  • Immunomodulatory effects of treatment with naproxen in patients with rheumatic disease.
  • The pharmacokinetic profile of naproxen suppository in man.
  • Skin permeability and local tissue concentrations of nonsteroidal anti-inflammatory drugs after topical application.
  • Naproxen sodium in the treatment of otitis
  • Predicting NSAID related ulcers--assessment of clinical and pathological risk factors and importance of differences in NSAID.
  • Anti-inflammatory drug actions on allergic responses in guinea-pig skin.
  • Anti-arthritic medication usage: United States, 1991.
  • Influence of naproxen on uterine PGF2 alpha and the antifertility effect of IUDs in rats.
  • Salicylate potentiates valproate-induced hyperammonemia in the rat.
  • Hydrosmotic response to vasopressin in frog skin. Control by endogenous factors.
  • Modulation of vasopressin-induced water permeability of the cortical collecting tubule by endogenous and exogenous prostaglandins.
  • The disposition of venlafaxine enantiomers in dogs, rats, and humans receiving venlafaxine.
  • Stereoselective disposition of naproxen glucuronide in the rat.
  • Diclofenac sodium (Voltarol): drug interactions and special studies.
  • Macromolecular prodrugs. XVI. Colon-targeted delivery--comparison of the rate of release of naproxen from dextran ester prodrugs in homogenates of various segments of the pig gastrointestinal (GI) tract.
  • Development of a new Bacillus carboxyl esterase for use in the resolution of chiral drugs.
  • Comparative effects of benoxaprofen and other anti-inflammatory drugs on bone damage in the adjuvant arthritic rat.
  • In vitro plasma protein binding of zileuton and its N-dehydroxylated metabolite.
  • Relationships between biophasic disposition and pharmacokinetic behavior in nonsteroid antiinflammatory drugs.
  • Structural requirements for binding of nonsteroidal anti-inflammatory drugs to human serum albumin.
  • Rat serum albumin modified by diflunisal acyl glucuronide is immunogenic in rats.
  • Prostaglandin biosynthesis by fat body from the tobacco hornworm, Manduca sexta.
  • In vivo susceptibility of Campylobacter pylori.
  • Correlation between ossification and inflammation using a rat experimental model.
  • Effect of tenidap on cartilage integrity in vitro.
  • Inhibition of inflammatory cell infiltration by bicyclic imidazoles, SK&F 86002 and SK&F 104493.
  • Pharmacologic characteristics as the basis for differential therapy using non-steroidal anti-inflammatory agents
  • Rabbit articular chondrocytes in soft agar are useful to test the effect of non-steroidal anti-inflammatory drugs on chondrocyte replication.
  • Hematologic and body fluid changes during simulated high altitude exposure in naproxen-treated rats.
  • Suppression of NF kappa B activation and NF kappa B-dependent gene expression by tepoxalin, a dual inhibitor of cyclooxygenase and 5-lipoxygenase.
  • High-performance liquid chromatographic method for the simultaneous quantitation of diflunisal and its glucuronide and sulfate conjugates in human urine.
  • Treatment of progressive chronic polyarthritis with a non-steroidal antirheumatic agent with a long half-life
  • General treatment of competitive binding as applied to the potentiometric ion probe technique: application to the interaction of nonsteroidal anti-inflammatory drugs with bovine serum albumin.
  • Immunoglobulin concentrations in first-degree relatives of epileptic patients with drug-induced IgA deficiency.
  • Effects of suprofen and other prostaglandin synthetase inhibitors in a new animal model for myometrial hyperactivity.
  • Effects of naproxen on connective tissue changes in the adjuvant arthritic rat.
  • Pharmacokinetics of a controlled release preparation of naproxen.
  • Antioxidant effect of copper(II) on photosensitized lipid peroxidation.
  • Polymorphonuclear leukocyte collagenase in carrageenin-induced inflammation: effect of nonsteroidal antiinflammatory drugs.
  • Effects of drugs on cell culture (I)
  • An expanded profile of cutaneous reactions to nonsteroidal anti-inflammatory drugs. Reports to a specialty-based system for spontaneous reporting of adverse reactions to drugs.
  • Conversion of a cyclooxygenase (CO) inhibitor into a 5-lipoxygenase (LO) inhibitor: a general route to novel orally active anti-inflammatory and anti-allergy drugs.
  • N-acylated derivatives of cyclohexylaniline with potential antiallergic and analgesic-antiinflammatory activity
  • X-ray powder diffraction data for selected drugs: furosemide, hydrochlorothiazide, naproxen, naproxen sodium, propranolol hydrochloride, and the halopheniramine maleates.
  • Spectrophotometric determination of complex formation constants of naproxen with caffeine, nicotinamide and salicylic acid in aqueous solution
  • Reactions of oxaprozin-1-O-acyl glucuronide in solutions of human plasma and albumin.
  • Factors affecting the determination of drugs and endogenous low molecular mass compounds in human serum by micellar electrokinetic capillary chromatography with direct sample injection.
  • Lipocortin 1 mediates dexamethasone-induced growth arrest of the A549 lung adenocarcinoma cell line.
  • Utility of naproxen in the differential diagnosis of fever of undetermined origin in patients with cancer.
  • Naproxen kinetics and disease activity in rheumatoid arthritis: a within-patient study.
  • Gastrointestinal blood loss during treatment with naproxen for rheumatoid arthritis.
  • Pharmacokinetic analysis of diethylcarbonate prodrugs of ibuprofen and naproxen.
  • Antiinflammatory drug-induced small intestinal permeability: the rat is a suitable model.
  • Response to furosemide during dehydration with and without naproxen pretreatment of kidney donors and renal transplant recipients.
  • Modern treatment of dysmenorrhea.
  • Salvage of ischemic rabbit ear by BW-755C and steroids, but not by indomethacin.
  • Salicylates inhibit PAF-acether-induced rat paw oedema when cyclooxygenase inhibitors are ineffective.
  • Naproxen: antirheumatic efficacy and safety in patients with pre-existing gastrointestinal disease.
  • A subchronic study of the effect of etodolac on the gastric mucosal prostaglandin levels in the rat.
  • The biosynthesis of 1a, 1b-dihomo-PGF2 and 1a,1b-dihomo-PGF2 alpha from 7, 10, 13, 16-docosatetraenoic acid by an acetone-pentane powder of sheep vesicular gland microsomes.
  • Alterations in the electroretinogram of newborn piglets by propionic acid-derivative nonsteroidal antiinflammatory drugs but not by indomethacin and diclofenac.
  • Enzyme-catalysed enantioselective hydrolysis of racemic naproxen nitrile.
  • Histologic studies on endometrium of menstruating monkeys wearing IUDs: comparative evaluation of drugs.
  • Evaluation of an enteric-coated naproxen pellet formulation.
  • Pityriasis rosea-like eruption after anti-inflammatory and antipyretic medication
  • Aspirin-like drugs, ethanol-induced rat gastric injury and mucosal eicosanoid release.
  • Induction of plasma exudation and inflammatory cell infiltration by leukotriene C4 and leukotriene B4 in mouse peritonitis.
  • Daily chronic headache in patients with migraine induced by abuse of ergotamine-analgesics: response due to a protocol of outpatient treatment
  • New antirheumatic agents: Fenoprofen calcium (Nalfon), naproxen (Naprosyn), and tolmetin sodium (Tolectin).
  • The effect of naproxen on fever in children with malignancies.
  • Inhibition of folate-dependent enzymes by non-steroidal anti-inflammatory drugs.
  • Submicron emulsion vehicle for enhanced transdermal delivery of steroidal and nonsteroidal antiinflammatory drugs.
  • Prostaglandin synthesis and fatty acid composition of phospholipids and triglycerides in skeletal muscle of chicks fed combinations of flaxseed oil and animal tallow.
  • Utilization of analgesics from 1970 to 1978. Prescription patterns in the county of Jamtland and in Sweden as a whole.
  • Effect on platelet aggregation of oral administration of 10 non-steroidal analgesics to humans.
  • Comparison of the gastrointestinal side effects of naproxen formulated as plain tablets, enteric-coated tablets, or enteric-coated granules in capsules.
  • Auranofin modulates gelatinase release from rat neutrophils.
  • Effect of naproxen on glucose metabolism and tolbutamide kinetics and dynamics in maturity onset diabetics.
  • Naproxen disposition in patients with alcoholic cirrhosis.
  • Naproxen inhibits hepatic glycogenolysis induced by Ca(2+)-dependent agents.
  • Calcium-and G-protein-related spasmolytic effects of nonsteroidal anti-inflammatory drugs on rat uterus contractions in vitro.
  • Central and peripheral haemodynamic effects of non-steroidal anti-inflammatory drugs in man.
  • Cholinergic and alpha-adrenergic stimulation of prostaglandin release by dog thyroid in vitro.
  • Enantiospecific high-performance liquid chromatographic (HPLC) determination of baclofen and its fluoro analogue in biological material.
  • The effect of antidiuretic hormone, indomethacin and naproxen on prostaglandin synthesis of experimentally infected and healthy kidneys.
  • Cancellous bone behavior in hindlimb immobilized rats during and after naproxen treatment.
  • Silicone-induced hypercalcaemia in haemodialysis patients.
  • The identification of ibuprofen and analogues in urine by pyrolysis gas chromatography mass spectrometry.
  • Studies on the effects of altered timing of parturition in the rat.
  • Effect of surfactants on percutaneous absorption of naproxen I: comparisons of rabbit, rat, and human excised skin.
  • Antagonism by meseclazone and other nonsteroidal anti-inflammatory drugs of bradykinin-induced bronchospasm.
  • Gastric mucosal damage induced by nonsalicylate nonsteroidal antiinflammatory drugs in rats is mediated systemically.
  • Effect of diclofenac-Na on 24-hour urinary excretion of creatinine, calcium, uric acid and glycosaminoglycans in adult patients with recurrent calcium oxalate nephrolithiasis.
  • Arachidonic acid-induced inflammation: inhibition by dual inhibitor of arachidonic acid metabolism, SK&F 86002.
  • Effect of systemic inhibition of prostaglandin synthesis on muscle protein balance after trauma in the rat.
  • Leflunomide (HWA 486) inhibits experimental autoimmune tubulointerstitial nephritis in rats.
  • Tepoxalin, a novel dual inhibitor of the prostaglandin-H synthase cyclooxygenase and peroxidase activities.
  • Prediction of human analgesic dosages of nonsteroidal anti-inflammatory drugs (NSAIDs) from analgesic ED50 values in mice.
  • Preliminary studies on the in vivo fate of FITC-dextrans and naproxen-dextran ester prodrugs administered i.v. to rabbits.
  • Meclofenamate sodium is an inhibitor of both the 5-lipoxygenase and cyclooxygenase pathways of the arachidonic acid cascade in vitro.
  • Ambulatory anesthesia. An inquiry study of patient satisfaction and therapeutic quality
  • Prostaglandin H synthase: perturbation of the tyrosyl radical as a probe of anticyclooxygenase agents.
  • Multiple sites for interaction of prostaglandin and vasopressin in toad urinary bladder.
  • Construction of a naproxen ion-selective electrode and its application to pharmaceutical analysis.
  • Inhibition of interleukin 1 induced chondrocyte protease activity by a corticosteroid and a nonsteroidal antiinflammatory drug.
  • (S)oxazepam glucuronidation is inhibited by ketoprofen and other substrates of UGT2B7.
  • Bioavailability of ketoprofen from orally administered ketoprofen-dextran ester prodrugs in the pig.
  • Plasma and synovial fluid kinetics, disposition, and urinary excretion of naproxen in horses.
  • Inhibition of in vivo leucocyte migration by NSAIDs.
  • Rapid high-performance liquid chromatographic methods for the determination of overdose concentrations of some non-steroidal anti-inflammatory drugs in plasma or serum.
  • Lipid peroxidation in rat liver microsomes during naproxen metabolism.
  • Inhibition of alveolar bone loss in beagles with the NSAID naproxen.
  • Multiple-dose pharmacokinetics of naproxen from a controlled-release tablet in healthy volunteers.
  • Studies on intestinal lymphatic absorption of drugs. II. Glyceride prodrugs for improving lymphatic absorption of naproxen and nicotinic acid.
  • Inhibition of in vitro lysozyme release from human granulocytes and monocytes by non-steroidal anti-inflammatory agents.
  • Mechanism of DNA cleavage mediated by photoexcited non-steroidal antiinflammatory drugs.
  • Influence of prodigiozan, methyluracil and levamisole on the anti-inflammatory effect of nonsteroid antiphlogistics
  • Cyclooxygenase inhibitors modify the relaxant effect of vasoactive intestinal polypeptide and substance P in isolated porcine ophthalmic artery.
  • The influence of NSAIDs on morphology of articular cartilage.
  • Synthesis and evaluation of morpholinoalkyl ester prodrugs of indomethacin and naproxen.
  • Adaptation of rat gastric mucosa to aspirin requires mucosal contact.
  • Effect of indomethacin and naproxen on the metabolism of glycosaminoglycans.
  • Pharmacokinetic results on naproxen prodrugs based on poly(ethyleneglycol)s.
  • A multiple-dose pharmacokinetic comparison of naproxen as a once-daily controlled-release tablet and a twice-daily conventional tablet.
  • In vitro displacement of phenytoin from protein binding by nonsteroidal antiinflammatory drugs tolmetin, ibuprofen, and naproxen in normal and uremic sera.
  • DNA strand breaks photosensitized by benoxaprofen and other non steroidal antiinflammatory agents.
  • Naproxen sodium and piroxicam in acute musculo-skeletal disorders.
  • Interaction of vasopressin and prostaglandins in the toad urinary bladder.
  • The effects of Azone and capsaicin on the permeation of naproxen through human skin.
  • Fully automated analysis of activities catalysed by the major human liver cytochrome P450 (CYP) enzymes: assessment of human CYP inhibition potential.
  • Link between drug absorption solubility and permeability measurements in Caco-2 cells.
  • The determination of naproxen by spectrofluorometry and its binding to serum proteins.
  • The effects of non-steroid anti-inflammatory drugs on leukocyte migration in carrageenin-induced inflammation.
  • Direct resolution of optically active isomers on chiral packings containing ergoline skeleton. 6. Enantioseparation of profens.
  • Influence of a non-steroid antirheumatic drug on serum and urinary zinc in healthy volunteers.
  • Effect of superoxide dismutase from bovine erythrocytes on different activity parameters in adjuvant-induced arthritis.
  • The action of flufenamic acid and other nonsteroidal anti-inflammatories on sulfate transport in the isolated perfused rat liver.
  • Effect of different types of intrauterine devices on intrauterine activity.
  • In vivo effects of non-steroidal antiinflammatory drugs on oxidative stress-related parameters of human erythrocytes.
  • Rapid characterization of the major drug-metabolizing human hepatic cytochrome P-450 enzymes expressed in Escherichia coli.
  • PGHS-2 inhibitors, NS-398 and DuP-697, attenuate the inhibition of PGHS-1 by aspirin and indomethacin without altering its activity.
  • The interaction of charged and uncharged drugs with neutral (HP-beta-CD) and anionically charged (SBE7-beta-CD) beta-cyclodextrins.
  • Relationship between naproxen plasma concentration and its anti-inflammatory effect in experimental hepatitis.
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  • Effects of certain antiarthritic agents on the synthesis of type II collagen and glycosaminoglycans in rat chondrosarcoma cultures.
  • The influence of the physicochemical characteristics and pharmacokinetic properties of selected NSAID's on their transdermal absorption.
  • Disease-induced alterations in plasma drug-binding proteins and their influence on drug binding percentages in dogs.
  • Wound collagen deposition in rats: effects of an NO-NSAID and a selective COX-2 inhibitor.
  • Improvement of the enantioselectivity of lipase-catalyzed naproxen ester hydrolysis in organic solvent.
  • A rapid, sensitive HPLC method for the determination of ganciclovir in human plasma and serum.
  • Foscarnet alters antidiuretic hormone-mediated transport.
  • Correlation of the antiexudative, analgesic and antipyretic components in the action of nonsteroid anti-inflammatory preparations
  • Quantitation and validation of cis-camphoric acid 3-methyl ester and cis-camphoric acid 1-methyl ester using CE.
  • Multicentre trial of naproxen and phenylbutazone in acute gout.
  • Nonspecific binding of drugs to human liver microsomes.
  • Correlation between drug release kinetics from proteineous matrices and protein folding: elasticity and compressibility study.
  • A food interaction study of bromfenac, naproxen sodium, and placebo in cesarean section patients.
  • Inhibition of human liver phenol sulfotransferase by nonsteroidal anti-inflammatory drugs.
  • Enzymatic resolution of racemic naproxen in a low aqueous-organic biphase system
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  • Antihypertensive properties of a nitric oxide-releasing naproxen derivative in two-kidney, one-clip rats.
  • The use of naproxen in the treatment of children with rheumatic fever.
  • Simultaneous analysis of naproxen, nabumetone and its major metabolite 6-methoxy-2-naphthylacetic acid in pharmaceuticals and human urine by high-performance liquid chromatography.
  • Use of nonsteroidal anti-inflammatory drugs and risk of fractures.
  • Molecular mechanism of naproxen photosensitization in red blood cells.
  • Auxin-induced ethylene triggers abscisic acid biosynthesis and growth inhibition.
  • Protective effect of SK&F 86002, a novel dual inhibitor of arachidonic acid metabolism, in murine models of endotoxin shock: inhibition of tumor necrosis factor as a possible mechanism of action.
  • Pseudoporphyria and nonsteroidal antiinflammatory agents in children with juvenile idiopathic arthritis.
  • Gastroprotective and ulcer healing effects of nitric oxide-releasing non-steroidal anti-inflammatory drugs.
  • Prostaglandin H synthase-2 inhibitors interfere with prostaglandin H synthase-1 inhibition by nonsteroidal anti-inflammatory drugs.
  • Prostaglandin biosynthesis by fat body from true armyworms, Pseudaletia unipuncta.
  • Non-steroidal anti-inflammatory drugs (NSAIDs) affect the glutathione (GSH) levels in the brain.
  • Pharmacokinetic/pharmacodynamic modeling of antipyretic and anti-inflammatory effects of naproxen in the rat.
  • Cyclic amide derivatives as potential prodrugs II: N-hydroxymethylsuccinimide- / isatin esters of some NSAIDs as prodrugs with an improved therapeutic index.
  • Simultaneous quantification of neutral and acidic pharmaceuticals and pesticides at the low-ng/l level in surface and waste water.
  • Enantiomeric purity of naproxen by liquid chromatographic analysis of its diastereomeric octyl esters.
  • Nonsteroidal anti-inflammatory drug therapy and gastric side effects. Does nabumetone provide a solution?
  • Endogenous prostaglandin E2 and insulin-like growth factor 1 can modulate the levels of parathyroid hormone receptor in human osteoarthritic osteoblasts.
  • Separation and determination of naproxen by reversed-phase high performance liquid chromatography
  • Determination of ibuprofen and naproxen in tablets.
  • Biliary excretion of acetaminophen-glutathione as an index of toxic activation of acetaminophen: effect of chemicals that alter acetaminophen hepatotoxicity.
  • Inhibition of tendon cell proliferation and matrix glycosaminoglycan synthesis by non-steroidal anti-inflammatory drugs in vitro.
  • Nimesulide reduces interleukin-1beta-induced cyclooxygenase-2 gene expression in human synovial fibroblasts.
  • Dapsone activation of CYP2C9-mediated metabolism: evidence for activation of multiple substrates and a two-site model.
  • The lack of awareness of the Israeli population regarding gastrointestinal complications from non-steroidal anti-inflammatory drugs
  • Localization of cyclooxygenase isozymes in cardiovascular tissues of dogs treated with naproxen.
  • Effect and tolerance of naproxen. Testing of a new Galenic preparation of an anti-rheumatic agent in an open clinical trial








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