Drugs online research references
Jpn J Antibiot. 1979 Jun;32(6):668-74.
[Sensitivity of frequent-occurring isolates in outpatients to routinely-used antibiotics (author's transl)]
[Article in Japanese]
Deguchi K.
The susceptibility of microorganisms (Staphylococcus aureus, Streptococcus pyogenes, Streptococcus pneumoniae, E. coli, Klebsiella pneumoniae, Salmonella spp. and Haemophilus influenzae) frequently occurring in outpatients (treated by practitioners) to six kinds of antibiotics [ampicillin (ABPC), cefazolin (CEZ), erythromycin (EM), minocycline (MNC), gentamicin (GM) and thiamphenicol (TP)] was determined by the standard method established by the Japan Society of Chemotherapy. 1) There were few multiple-antibiotic-resistant urine isolates from patients with a simple urinary tract infection, whereas urine isolates from patients with a complicated urinary tract infection contained many multiple-antibiotic resistant organisms. 2) Isolates from patients with a respiratory tract infection (sputum and tonsillar secretions isolates) and isolates from patients with acute purulent otitis media (purulent discharge isolates) contained few multiple-antibiotic-resistant organisms except for EM-resistant Streptococcus pyogenes. 3) Superficial pus isolates contained many multiple-antibiotic-resistant organisms, while bile isolates were relatively free from multiple-antibiotic resistant organisms. 4) When the results of the previous8,9) and present investigations were compared with the reports of other Japanese investigators1,5,6), suggestive evidence was provided that organisms resistant to macrolides and chloramphenicol showed a tendency to decrease, whereas organisms resistant to penicillins, cephalosporins and aminoglycoside antibiotics were on the increase.
online pharmacy ref source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=381708&dopt=Abstract
Arch Immunol Ther Exp (Warsz). 1985;33(6):851-6.
Characteristics of Mycoplasma strains isolated from stallion semen.
Zgorniak-Nowosielska I, Kosiniak K, Slagowska A.
Eleven mycoplasma strains were isolated from the semen of 24 stallions. Eight of these strains were identified as Mycoplasma equigenitalium. Three strains which hydrolized arginine could not be identified. The growth inhibition test with immune sera against M. arginini and M. equirhinis was negative. Antibiotic sensitivity test showed that all strains were sensitive to four antibiotic of tetracycline group (oxytetracyclin, minocycline, transcycline and vibramycin). Lincomycin and gentamycin appeared to be the most active against all the strains. Comparative analysis of routine semen examination did not reveal any difference between ejaculates infected with mycoplasma and free of these organisms. However, the levels of certain biochemical components of the semen plasma (glycerylphosphorylcholine, ergothioneine, fructose and of the semen plasma (glycerylphosphorylcholine, ergothioneine, fructose and total protein) from mycoplasma-positive ejaculates were significantly lower than in the semen plasma from mycoplasma free ejaculates.
online pharmacy ref source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3833120&dopt=Abstract
Jpn J Antibiot. 1985 Feb;38(2):199-202.
[Antibiotic susceptibility of the clinically isolated staphylococcal strains resistant to cephalosporin derivatives]
[Article in Japanese]
Arai T.
Incidence of cephalosporin-resistant staphylococcal infections is increasing recently. We tried to find out the possible first choice antibiotic for these infections. We estimated minimal inhibitory concentrations (MIC) of each one of the broad spectrum antibiotics with different mode of actions as well as representative drugs of penicillins and cephalosporins against strains of Staphylococcus epidermidis and Staphylococcus aureus. Trend of antibiotic susceptibility of S. epidermidis was found to be as same as that of S. aureus. MIC of minocycline was found to be the lowest in the drugs tested, and there found no resistant strains. MIC of erythromycin was next low but more than a half strains were found to be resistant to this drug. Some of the strains were thought to be treated with amikacin or sulfonamides by the MIC against them, but there also found many resistant strains. Therefore, use of these drugs should be decided after sensitivity test of the causative bacteria. Most of the strains were found not to be treated with beta-lactam antibiotics. In conclusion, minocycline could be the only one first choice drug for staphylococcal infections before antibiotic susceptibility test of the causative strains in the present moment.
online pharmacy ref source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3847517&dopt=Abstract
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