Drugs online research references
Cardiovascular effects of enflurane and asphyxia during long-term beta 1-adrenoceptor blockade.
Psychosocial stress causes endothelial injury in cynomolgus monkeys via beta1-adrenoceptor activation.
Changes in plasma epinephrine concentration and in heart rate during head-up tilt testing in patients with neurocardiogenic syncope: correlation with successful therapy with beta-receptor antagonists.
Interaction between epinephrine and renal nerves in control of renin secretion rate.
Automated definition of the enzymology of drug oxidation by the major human drug metabolizing cytochrome P450s.
Sudden death related to advanced coronary atherosclerosis in mini-pigs: influence of some drugs.
Quality of life five years after myocardial infarction.
In vivo microdialysis evidence for central serotonin1A and serotonin1B autoreceptor blocking properties of the beta adrenoceptor antagonist (-)penbutolol.
Ten years of clinical experience with metoprolol.
Investigations in animal experiments into the influence of the beta-1-selective blocking agent metoprolol on the cardiovascular and metabolic side effects of the tocolytic fenoterol
Regression of structural cardiovascular changes by antihypertensive therapy in spontaneously hypertensive rats.
Complaints of cold extremities among patients on antihypertensive treatment.
Effects of chronic felodipine treatment on renal function and morphology in SHR.
Efficency of tocoylsis by fenoterol and fenoterol in combination with a beta-1-blocking compound
Increased shock-induced fighting with supersensitive beta-adrenergic receptors.
Capillary supercritical fluid chromatography of aliphatic amines. Studies on the selectivity and symmetry with three different columns using carbon dioxide or nitrous oxide as mobile phase.
Identification of critical formulation and processing variables for metoprolol tartrate extended-release (ER) matrix tablets.
Role of sympathetic nerves for the stimulation of the renin system by angiotensin II receptor blockade.
Protection by blockers against human low density lipoprotein peroxidation induced by oxygen free radicals
Analysis of oxprenolol in formulations by high-performance liquid chromatography.
The release of serotonin from rat duodenal enterochromaffin cells by adrenoceptor agonists studied in vitro.
Maternal treatment with a cardioselective beta-blocking agent--consequences for the ovine fetus during intermittent asphyxia.
Characterization of functional beta-adrenoceptor subtypes in rabbit urinary bladder smooth muscle.
Isoproterenol and the genesis of reperfusion-induced arrhythmias in isolated rat heart: adrenoceptor or free radical-mediated mechanisms?
Use of cyclic boronates for GC/MS screening and quantitation of beta-adrenergic blockers and some bronchodilators.
The racemic metoprolol H2-antagonist interaction.
Central and peripheral haemodynamic effects of prenalterol in patients with coronary heart disease.
A comparison of a short half-life marker (low-dose isoniazid), a long half-life pharmacological indicator (low-dose phenobarbitone) and measurements of a controlled release 'therapeutic drug' (metoprolol, Metoros) in reflecting incomplete compliance by volunteers.
The modulation of head-twitch behaviour by drugs acting on beta-adrenoceptors: evidence for the involvement of both beta 1- and beta 2-adrenoceptors.
Effects of a cardiotonic agent, TA-064, on isolated canine cerebral, coronary, femoral, mesenteric, and renal arteries.
Myocardial metabolic and hemodynamic effects of a sustained intravenous infusion of nifedipine with and without metoprolol in patients with unstable angina.
Effect of beta-blocking agents and angiotensin II on isoproterenol-stimulated renin release from rat kidney slices.
Disparate effects of carvedilol versus metoprolol treatment of stroke-prone spontaneously hypertensive rats on endothelial function of resistance arteries.
Adrenoceptor blocking agents. Compounds related to metoprolol.
The influence of two histamine H2-receptor antagonists, cimetidine and ranitidine, on the plasma levels and clinical effect of nifedipine and metoprolol.
The treatment of essential hypertension in the hospital and in the office: is there a difference?
Catalytic activities of human debrisoquine 4-hydroxylase cytochrome P450 (CYP2D6) expressed in yeast.
Selectivity of bevantolol hydrochloride, a beta 1-adrenoceptor antagonist, in asthmatic patients.
Effects of hypercholesterolemia on beta adrenoceptors in the rabbit heart.
Media hypertrophy in hypertensive coronary resistance vessels.
Regression of cardiac hypertrophy after therapy in animal hypertension.
The cholinergic-adrenergic hypothesis of depression reexamined using clonidine, metoprolol, and physostigmine in an animal model.
Observations in man of hypoglycaemia during selective and non-selective beta-blockade.
The relationship between casual and ambulatory blood pressure in essential hypertension: the influence of work, duration of hypertension and antihypertensive treatment.
Comparison of the hypotensive and metabolic effects of metoprolol therapy with a high fibre, low sodium, low fat diet in hypertensive type 2 diabetic subjects.
Regression of myocardial hypertrophy in hypertensives on chronic beta-receptor block
The beta 2-adrenoceptor agonists clenbuterol and salbutamol enhance the hypothermic action of 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) in mice by a central mechanism.
Selective labelling of beta 1-adrenoceptors in rabbit lung membranes by (-)3Hbisoprolol.
Selective beta(1)-blockade improves cardiac bioenergetics and function and decreases neuroendocrine activation in rats during early postinfarct remodeling.
Is pindolol a mixed agonist-antagonist at central serotonin (5-HT) receptors?
Effects of escapable and inescapable foot-shock on rat atrial beta-adrenoceptors.
Different effects of inhibitors on the O- and N-demethylation of codeine in human liver microsomes.
Lipophilic beta-blockers inhibit rat skeletal muscle mitochondrial respiration.
Hemodynamic effects of inosine in combination with positive and negative inotropic drugs: studies on rats in vivo.
Reduction of catecholamine-induced cardiovascular malformations in the chick embryo with metoprolol.
Beta-adrenoceptor subtypes in the detrusor of guinea-pig urinary bladder.
Influence of adrenoceptor agonists and antagonists on fluid secretion in small bowel obstruction.
The role of prostaglandins in the alpha- and beta-adrenoceptor mediated renin release response to graded renal nerve stimulation.
Screening of beta-blockers in human serum by ion-pair chromatography and their identification as methyl or acetyl derivatives by gas chromatography-mass spectrometry.
Desensitization of the insulin receptor by antireceptor antibodies in vivo is blocked by treatment of mice with beta-adrenergic agonists.
Metoprolol-paroxetine interaction in human liver microsomes: stereoselective aspects and prediction of the in vivo interaction.
Effects of beta-adrenergic agonists on splanchnic vascular volume and cardiac output.
Kinetics of 1,2-dinitroglycerin following sustained release nitroglycerin: influence of propranolol and metoprolol.
Beta-adrenoceptor blocker intoxication: epidemiological data. Prenalterol as an alternative in the treatment of cardiac dysfunction.
Hypotensive effect of intracerebroventricular injection of norepinephrine and its modulation by alpha and beta adrenergic blockers in conscious rabbits.
Abnormality in plasma catecholamines and myocardial adrenoceptors in cardiomyopathic BIO 53.58 Syrian hamsters and improvement by metoprolol treatment.
Hemodynamic effects of intravenous metoprolol in acute myocardial infarction: the role of anatomic subsets in predicting patient response.
Factors affecting iontophoretic mobility of metoprolol.
Cardiac autonomic blockade in sinus disease and indication for a pacemaker
The effect of metoprolol on intra-ocular pressure in glaucoma. A pilot study.
Beta 1-adrenergic mechanism is involved in stress-induced increase in arousal.
Silent myocardial ischemia--risk for sports in coronary groups?
Effects of dobutamine on isolated canine cerebral, coronary, mesenteric, and renal arteries.
Central nervous system kinetics of atenolol and metoprolol in the dog during long term treatment.
Increase in glucose and lactate output and perfusion resistance by stimulation of hepatic nerves in isolated perfused rat liver: role of alpha 1-, alpha 2-, beta 1- and beta 2-receptors.
Effects of metoprolol on left ventricular function in rats with myocardial infarction.
An in vitro assessment of cellular and humoral immune function in pulmonary tuberculosis: correction of defective neutrophil motility by ascorbate, levamisole, metoprolol and propranolol.
Treatment of life-threatening ventricular arrhythmias by a combination of antiarrhythmic drugs and right ventricular pacing.
Relaxing activity of two linear diterpenes from Cystoseira brachycarpa var. balearica on the contractions of intestinal preparations.
Free radical generation, lipid peroxidation and essential fatty acids in uncontrolled essential hypertension.
Cardiac adaptation and its limitation in an experimental model of congestive heart failure.
Efficient high-performance liquid chromatographic assay for the simultaneous determination of metoprolol and two main metabolites in human urine by solid-phase extraction and fluorescence detection.
Rapid high-performance liquid chromatographic method for the measurement of the enantiomers of metoprolol in serum using a chiral stationary phase.
Simple high-performance liquid chromatographic method for the determination of ranitidine in human plasma.
Effect of 5-HT(1A) receptor ligands on Fos-like immunoreactivity in rat brain: evidence for activation of noradrenergic transmission.
The effect of metoprolol on left ventricular systolic and diastolic function in essential hypertension.
Antinuclear antibodies and lupus induced during treatment of arterial hypertension. Role of beta-blockers and alpha-methyldopa
Effect of propofol on cerebrospinal fluid pressure and cerebral perfusion pressure in patients undergoing craniotomy.
Antagonistic effects of alpha-adrenoceptor blocking agents on arrhythmias, enzyme release, and myocardial necrosis in isolated rat hearts with coronary occlusion and reperfusion.
Instrumental color measurement: a method for judging the appearance of tablets.
Beta-adrenergic receptor mechanisms in rat parotid glands: activation by nerve stimulation and 3-isobutyl-1-methylxanthine.
Bioenergetics in clinical medicine. III. Inhibition of coenzyme Q10-enzymes by clinically used anti-hypertensive drugs.
Metoprolol in diabetes mellitus: effect on glucose homeostasis.
Pronounced accumulation of metoprolol in ischemic myocardium after coronary venous retroinfusion.
Safety and tolerability of metoprolol OROS in hypertension treatment.
Attenuation of response to mental stress in patients with essential tremor treated with metoprolol.
Identification of receptor mechanism mediating epinephrine-induced arrhythmias during halothane anesthesia in the dog.
Selected ion monitoring of metoprolol and two metabolites in plasma and urine using deuterated internal standards.
Triiodothyronine-induced changes in function, metabolism and weight of the rat heart: effects of alpha- and beta-adrenergic blockade.
Carvedilol and its metabolites suppress endothelin-1 production in human endothelial cell culture.
Cardiac contractile and metabolic effects mediated via the myocardial H2-receptor adenylate cyclase system. Characterization of two new specific H2-receptor agonists, impromidine and dimaprit, in the guinea pig and human myocardium.
Acute effects of combined alpha/beta-adrenoceptor blockade v combined beta-receptor and slow channel calcium blockade in ischemic heart disease complicated by hypertension. Hemodynamic and adrenergic responses.
Does chronic prenatal methadone exposure affect beta-receptor subtypes in placental, fetal and maternal brain homogenates?
Effect of felodipine and metoprolol on muscle and skin arteries in hypertensive patients.
Defective metabolism of metoprolol in poor hydroxylators of debrisoquine.
Effect of rifampicin on metoprolol and antipyrine kinetics.
Transdermal delivery of metoprolol. II: In-vitro skin permeation and bioavailability in hairless rats.
Administration of metoprolol in refractory and severe heart failure
Effects of chronic metoprolol and sulphinpyrazone on human lymphocyte beta-adrenoceptors.
Identification and characterisation of beta-adrenoceptors in guinea-pig skeletal muscle.
Characteristics of 125I-iodocyanopindolol binding to beta-adrenergic and serotonin-1B receptors of rat brain: selectivity of beta-adrenergic agents.
Bioavailability of metoprolol in young adults and the elderly, with additional studies on the effects of metoclopramide and probanthine.
Pharmacokinetics of metoprolol enantiomers following single and multiple administration of racemate in rat.
Chemical aspects of metoprolol metabolism. Asymmetric synthesis and absolute configuration of the 3-4-(1-hydroxy-2-methoxyethyl)phenoxy-1-(isopropylamino)-2-propanols , the diastereomeric benzylic hydroxylation metabolites.
Pharmacokinetics of metoprolol and its metabolite alpha-OH-metoprolol in healthy, non-smoking, elderly individuals.
Effects of long term metoprolol administration on the electrocardiogram of rats infected with T cruzi.
Different effects of metoprolol and chlorthalidone on serum lipoprotein levels in mild hypertension. Possible implications for coronary heart disease risk status.
Effect of intravenous metoprolol on left ventricular performance in Q-wave acute myocardial infarction.
Separation of enantiomeric amines by ion-pair chromatography.
Brain noradrenaline and anaesthesia: further characterization of the beta-receptor.
A fixed combination of metoprolol and hydrochlorothiazide for hypertension: a multi-centre study.
Pharmacological characterization of beta-adrenoceptors mediating relaxation of the rat urinary bladder in vitro.
Failure of intravenous metoprolol to limit acute myocardial infarct size in a nonreperfused porcine model.
Experimental study of metoprolol-induced side effects
Effects of penbutolol and metoprolol on blood pressure, plasma catecholamines and renin activity in hypertensive patients.
Time-dependent effect of metoprolol in middle-aged and old patients with angina
Absence of DNA damage in mice and rats given high doses of five beta-adrenergic blocking agents.
Long-term results of migraine prophylaxis with flunarizine and beta-blockers.
Sympathetic nerves modify mitochondrial and capillary growth in normotensive and hypertensive rats.
The beta2-adrenergic modulator celiprolol reduces insulin resistance in obese Zucker rats.
Effects of long-term monotherapy with enalapril, metoprolol, and digoxin on the progression of left ventricular dysfunction and dilation in dogs with reduced ejection fraction.
Anti-hypertensive effect of metoprolol in spontaneously hypertensive rats.
Pharmacological characterization and anatomical localization of prejunctional beta-adrenoceptors in the rat kidney.
Beta-blockers: propranolol, metoprolol, atenolol, pindolol, alprenolol and timolol, manifest atherogenicity on in vitro, ex vivo and in vivo models. Elimination of propranolol atherogenic effects by papaverine.
Adipose tissue and skeletal muscle blood flow during mental stress.
Evaluation of the effect of metoprolol on energy metabolism in the ischaemic myocardium in relation to regional myocardial blood flow.
Increased oral clearance of metoprolol in pregnancy.
Clinical usefulness of 123I meta-iodobenzylguanidine imaging in predicting the effectiveness of beta blockers for patients with idiopathic dilated cardiomyopathy before and soon after treatment.
Design of a new multiple-unit controlled-release formulation of metoprolol--metoprolol CR.
Action of calcium channel and beta-adrenergic blocking agents in bilayer lipid membranes.
Interaction of metoprolol and lidocaine on the ventricular fibrillation threshold in the anesthetized dog.
Functional importance of myocardial relaxation in patients with congestive heart failure.
Quantitative evaluation of myocardial injury induced by acute cerebral ischaemia and its prevention by beta 1-adrenergic blockade. An ultrastructural morphometry study.
Establishment and characterization of steroidogenic granulosa cells expressing beta(2)-adrenergic receptor: regulation of adrenodoxin and steroidogenic acute regulatory protein by adrenergic agents.
Renal selective N-acetyl-L-gamma-glutamyl prodrugs: studies on the selectivity of some model prodrugs.
Exaggerated sympathetic nervous system response to extended psychological stress in offspring of hypertensives.
Stimulatory effects of neuronally released norepinephrine on renin release from rat kidney cortical slices.
Efficacy of betaxolol in neuroleptic-induced akathisia.
Haemodynamic effects of a new beta 1-receptor agonist in acute myocardial infarction. A useful antidote to unwanted cardiac effects of beta-blocking agents.
Debrisoquine polymorphism and the metabolism and action of metoprolol, timolol, propranolol and atenolol.
A role for N-methyl-D-aspartate receptors in norepinephrine-induced long-lasting potentiation in the dentate gyrus.
Effects of selective and non-selective beta 1-blockade on renin secretion in the isolated rat kidney.
Reduction in infarct size and enhanced recovery of systolic function after coronary thrombolysis with tissue-type plasminogen activator combined with beta-adrenergic blockade with metoprolol.
Effect of selective versus nonselective beta blockade on QT dispersion in patients with nonischemic dilated cardiomyopathy.
Effects of adrenergic and cholinergic drugs on electrical and mechanical activities of the rat cauda epididymidis in vitro.
Pathway specificity of noradrenergic plasticity in the dentate gyrus.
Effect of CL 316,243, a novel beta 3-adrenoceptor agonist, on insulin secretion in perfused mouse pancreas.
Antianginal drug effects on normal, ischemic and scar myocardial segments in man.
Noradrenergic control of ocular dominance plasticity in the visual cortex of dark-reared cats.
Simultaneous determination of propranolol or metoprolol in the presence of benzodiazepines in the plasma by gas chromatography.
Beta blockade for patients of mitral stenosis in sinus rhythm.
Circadian phase dependency of the effects of different beta-receptor blocking drugs on motor activity of rats. Importance of drug lipophilicity.
Simultaneous determination of metoprolol and alpha-hydroxymetoprolol in human plasma and urine by liquid chromatography with a preliminary observation on metoprolol oxidation in Japanese subjects.
Assessment of optimal dose of diuretic associated with fixed dose of beta-blocking: a new experimental model based on multiple sampling of blood pressure performed by self-measurements.
Electrophysiologic effects of intravenous metoprolol.
Plasma levels and negative chronotropic effect of metoprolol following single doses of a conventional and sustained-release formulation.
Responsiveness to dopamine of isolated epicardial coronary arteries from humans, monkeys, and dogs.
beta-Adrenergic regulation of lipolysis and blood flow in human skeletal muscle in vivo.
The actions of tulobuterol on isolated preparations of gravid human myometrium.
The effects of metoprolol on systolic times in patients with systemic arterial hypertension. Polygraphic study
Potentiation by (-)Pindolol of the activation of postsynaptic 5-HT(1A) receptors induced by venlafaxine.
Autonomic neural regulation of intact Purkinje system of dogs.
Cardiac antiischemic effect of metoprolol: role of beta-blockade within the ischemic region.
Effects of autonomic agents on the secretion of glycoproteins from the secretory cells of the major salivary glands in rats.
Beta-2 adrenoceptor control of the venous circulation in intact dogs.
Effects of footshock stress on the sensitivity of the isolated rat pacemaker to catecholamines.
Coupled-column chromatography on immobilized protein phases for direct separation and determination of drug enantiomers in plasma.
Metoprolol in the treatment of multifocal atrial tachycardia.
Gastrointestinal transit of Oros drug delivery systems in healthy volunteers: a short report.
Aggravation and provocation of ventricular arrhythmias by antiarrhythmic drugs.
Comparative clinical study of metoprolol and timolol
Effects of ACE inhibition and beta-blockade on skeletal muscle fiber types in dogs with moderate heart failure.
Design and pharmacokinetics of Logimax, a new extended-release combination tablet of felodipine and metoprolol.
Densitometric determination of metoprolol tartrate in pharmaceutical dosage forms.
Myocardial oxygen tension and capillary density in the isolated perfused rat heart during pharmacological intervention.
Metoprolol and mephenytoin oxidation polymorphisms in Far Eastern Oriental subjects: Japanese versus mainland Chinese.
Hemodynamic responses to paraventricular nucleus disinhibition with bicuculline in conscious rats.
High-performance liquid chromatographic determination of metoprolol in plasma.
Effects of salbutamol upon performance on an operant screen for antidepressants.
An evaluation of the perioperative efficacy of selective beta 1-blockade in coronary surgery. Studies with a late preoperative dose of metoprolol.
Beta-adrenoceptor blocker pharmacokinetics and the oral contraceptive pill.
Pharmacokinetic and pharmacodynamic properties of a new controlled-release formulation of metoprolol: a comparison with conventional tablets.
Pharmacokinetic and pharmacodynamic interactions between phenprocoumon and atenolol or metoprolol.
Aging and the pharmacokinetics and metabolism of metoprolol enantiomers in the rat.
A comparison of the pharmacokinetics of atenolol, metoprolol, oxprenolol and propranolol in elderly hypertensive and young healthy subjects.
Pharmacokinetics and pharmacodynamics of verapamil in combination with atenolol, metoprolol and propranolol.
Acute and steady-state pharmacokinetics and antihypertensive effects of felodipine in patients with normal and impaired renal function.
Haemodynamic effects and pharmacokinetics of a new selective beta1-adrenoceptor agonist, prenalterol, and its interaction with metoprolol in man.
Oxygen radical system in chronic infarcted rat heart: the effect of combined beta blockade and ACE inhibition.
CYP2D6 genotype and phenotyping by determination of dextromethorphan and metabolites in serum of healthy controls and of patients under psychotropic medication.
Activation of carbonic anhydrase by beta-adrenergic agonists and inhibition by beta-adrenergic blockers.
Preservation of membrane phospholipids by propranolol, pindolol, and metoprolol: a novel mechanism of action of beta-blockers.
Central propranolol and pindolol, but not atenolol nor metoprolol, inhibit sexual behavior in male rats.
Beta-adrenergic signalling and threshold adrenaline concentration for induction of fibrillation in the perfused heart pretreated with antihypertensive drugs.
Cardiac sympathetic activity estimated by 123I-MIBG myocardial imaging in patients with dilated cardiomyopathy after beta-blocker or angiotensin-converting enzyme inhibitor therapy.
Stress-induced alteration in the lipolytic response to beta-adrenoceptor agonists in rat white adipocytes.
The relative bioavailability of metoprolol following oral and rectal administration to volunteers and patients.
TR146 cells grown on filters as a model of human buccal epithelium: IV. Permeability of water, mannitol, testosterone and beta-adrenoceptor antagonists. Comparison to human, monkey and porcine buccal mucosa.
Safety, hemodynamic profile, and feasibility of dobutamine stress technetium myocardial perfusion single-photon emission CT imaging for evaluation of coronary artery disease in the elderly.
Oxidative metabolism of cinnarizine in rat liver microsomes.
Enhanced pressor response to carotid occlusion in commNTS-lesioned rats: possible efferent mechanisms.
Development of a more rapid, reduced serum culture system for Caco-2 monolayers and application to the biopharmaceutics classification system.
Middle cerebral artery blood velocity during exercise with beta-1 adrenergic and unilateral stellate ganglion blockade in humans.
Screening and confirmatory analysis of beta-agonists, beta-antagonists and their metabolites in horse urine by capillary gas chromatography-mass spectrometry.
Effect of serotonergic drugs on footshock-induced ultrasonic vocalization in adult male rats.
Angerlike behavioral state potentiates myocardial ischemia-induced T-wave alternans in canines.
Impaired beta-adrenergic control of immune function in patients with chronic heart failure: reversal by beta1-blocker treatment.
The Rational for the Use of A -Blockers in the Treatment of Congestive Heart Failure.
Nebivolol, carvedilol and metoprolol do not influence cardiac Ca(2+) sensitivity.
Low-dose ACE with alpha- or beta-adrenergic receptor inhibitors have beneficial SHR cardiovascular effects.
Prophylactic treatment of classical and non-classical migraine with metoprolol--a comparison with placebo.
Structural and functional adaptation in the rat myocardium and coronary vascular bed caused by changes in pressure and volume load.
Enantiomeric separation of metoprolol and alpha-hydroxymetoprolol by liquid chromatography and fluorescence detection using a chiral stationary phase.
Evidence that RU 24969-induced locomotor activity in C57/B1/6 mice is specifically mediated by the 5-HT1B receptor.
Brain energy metabolism during controlled reduction of cerebral perfusion pressure in severe head injuries.
Constitutive activity of the human beta(1)-adrenergic receptor in beta(1)-receptor transgenic mice.
Upregulation of functional beta(3)-adrenergic receptor in the failing canine myocardium.
Scavenger effect of experimental and clinically used cardiovascular drugs.
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Adrenergic blocking agents and lipoprotein lipase activity.
The impact of specialists on prescribing by general practitioners.
beta-Adrenoceptor blockade enhances the anticonvulsant effect of glutamate receptor antagonists against maximal electroshock.
Detection of illegal clenbuterol use in calves using hair analysis. Application in meat quality control.
Prediction of dissolution-absorption relationships from a continuous dissolution/Caco-2 system.
Controlled drug release from gels using surfactant aggregates. II. Vesicles formed from mixtures of amphiphilic drugs and oppositely charged surfactants.
Atrial natriuretic peptide and the natriuresis due to acute beta-blockade in conscious hypertensive rats.
Ischemic and reperfusive release of the endogenous purines and its influence on the myocardial viability during beta-adrenergic blockade.
Propranolol and metoprolol enhance the anticonvulsant action of valproate and diazepam against maximal electroshock.
Comparison of the affinity of beta-blockers for two states of the beta 1-adrenoceptor in ferret ventricular myocardium.
Effect of metoprolol on 24-hour urinary excretion of adrenal steroids and kallikrein in patients with essential hypertension.
Equal Efficacy and Improved Tolerability with 50 mg Controlled-Release Metoprolol Compared with 100 mg Conventional Metoprolol in Hypertensive Patients.
Screening drugs for metabolic stability using pulsed ultrafiltration mass spectrometry.
Different effects of carvedilol, metoprolol, and propranolol on left ventricular remodeling after coronary stenosis or after permanent coronary occlusion in rats.
Goteborg Metoprolol Trial: clinical observations.
Effects of thyroid hormone and beta-blocking agents on plasma amino acids in rats.
Influence of input rate on the stereospecific and nonstereospecific first pass metabolism and pharmacokinetics of metoprolol extended release formulations.
Bucindolol displays intrinsic sympathomimetic activity in human myocardium.
The myocardium-protective Gly-49 variant of the beta 1-adrenergic receptor exhibits constitutive activity and increased desensitization and down-regulation.
Novel metrics to compare dissolution profiles.
Effects of NaHCO3, alpha-, and beta-adrenergic blockade on albuminuria after swimming in splenectomized dogs.
Comparison of the neuroprotective effects of adrenoceptor drugs in retinal cell culture and intact retina.
Beta-adrenoceptor blockers and the blood-brian barrier.
Negative inotropic effects and the hydrophobicity of beta-adrenergic blocking agents.
Effects of cardioselective and nonselective beta-adrenergic antagonists on pulmonary mechanics.
Gastric, intestinal and colonic absorption of metoprolol in the rat.
Polyrotaxane approach for synthesis of continuous beds for capillary electrochromatography.
Adrenoceptors in avian and fish pigment cells.
Influence of beta-adrenoceptor antagonists on hemorrhage-induced cellular immune suppression.
Pharmacological blockade of the dive response: effects on heart rate and diving behaviour in the harbour seal (Phoca vitulina).
Clinical effectiveness of beta-adrenoblockers and their effects on copulative function in patients with hypertension
Carvedilol increases the production of interleukin-12 and interferon-gamma and improves the survival of mice infected with the encephalomyocarditis virus.
Sodium alginate microspheres of metoprolol tartrate for intranasal systemic delivery: development and evaluation.
The enhanced plasma levels of soluble tumor necrosis factor receptors (sTNF-R1; sTNF-R2) and interleukin-10 (IL-10) in patients suffering from chronic heart failure are reversed in patients treated with beta-adrenoceptor antagonist.
Stability of neurohumoral effects of losartan combined with metoprolol in chronic cardiac low output
Patterns of antihypertensive agents use in 11,947 Colombian patients
Clinical application of combined beta 2-stimulation and beta 1-blockade in tocolysis
Enatiomeric separation of beta-blocking agents and analogs
Isozyme-specific induction of low-dose aspirin on cytochrome P450 in healthy subjects.
Enantiomeric separation of beta-blockers by HPLC using (R)-1-naphthylglycine and 3,5-dinitrobenzoic acid as chiral stationary phase.
Nebivolol prevents vascular NOS III uncoupling in experimental hyperlipidemia and inhibits NADPH oxidase activity in inflammatory cells.
Statin therapy restores sympathovagal balance in experimental heart failure.
Usefulness of intravenous metoprolol during positive isoproterenol tilt-table test in the choice of treatment for neurocardiogenic syncope.
Stereoselective metabolism of metoprolol: enantioselectivity of alpha-hydroxymetoprolol in plasma and urine.
Administration of maximal or median doses of drugs in cardiovascular diseases?
Antihypertensive treatment and heart rate variability in diabetic patients: role of cardiac autonomic neuropathy.
Direct analysis of drugs in plasma by column-switching liquid chromatography-mass spectrometry using a methylcellulose-immobilized reversed-phase pretreatment column.
Long-term beta 1-selective adrenergic blockade and adrenergic receptors in human subcutaneous adipocytes.
Thin-layer chromatographic analysis of some beta-blocking drugs in plasma.
Partial agonist activity of bucindolol is dependent on the activation state of the human beta1-adrenergic receptor.
Effects of calcium antagonist, angiotensin-converting enzyme inhibitors and beta-blocker on hemodynamic and sympathetic nerve responses to exercise in essential hypertension
Clinical and metabolic effects of cardioselective beta-adrenoblockers nebivolol and metoprolol in patients with hypertension and ischemic heart disease associated with type 2 diabetes
Improvement of peak shape and separation performance of beta-blockers in conventional reversed-phase columns using solvent modifiers.
Beta 1- and beta 2-adrenoceptor binding and functional response in right and left atria of rat heart.
Beta-adrenoceptor activation plays a role in the reverse rate-dependency of effective refractory period lengthening by dofetilide in the guinea-pig atrium, in vitro.
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pH-dependent bidirectional transport of weakly basic drugs across Caco-2 monolayers: implications for drug-drug interactions.
Evaluation of teicoplanin chiral stationary phases of 3.5 and 5 microm inside diameter silica microparticles by polar-organic mode capillary electrochromatography.
The effect of the beta 1-blocker metoprolol on cyclic 3',5'-adenosine monophosphate in various tissues during long-term tocolysis with fenoterol. Animal experiments on the question of the interactive effects of the principal and adverse effects of beta 2-mimetics with special regard to fetal cardioprotection
Decreased heart rate recovery after exercise in patients with congestive heart failure: effect of beta-blocker therapy.
Beta-adrenoceptor antagonists increase sinus arrhythmia, a vagotonic effect.
beta-Adrenoceptor antagonists inhibit the behavioural responses of rats to increased brain 5-hydroxytryptamine.
Neuromedin U facilitates oxytocin release from the pituitary via beta adrenoceptors.
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In Process Citation
Drugs for preventing migraine headaches in children.
Beta-adrenoceptor antagonists and human platelets: relationship of effects to lipid solubility.
Increased exercise ejection fraction and reversed remodeling after long-term treatment with metoprolol in congestive heart failure: a randomized, stratified, double-blind, placebo-controlled trial in mild to moderate heart failure due to ischemic or idiopathic dilated cardiomyopathy.
Action of agonists and antagonists on adrenergic receptors in isolated porcine coronary arteries.
Beta-blocker brain concentrations in man.
Strain rate acceleration yields a better index for evaluating left ventricular contractile function as compared with tissue velocity acceleration during isovolumic contraction time: an in vivo study.
Characterization of the antagonism with metoprolol, ICI 147,798, pindolol, mepindolol and bopindolol on the responses of the rat left atria to isoprenaline.
Results of pharmacoepidemiological study of arterial hypertension in Russia
Metoprolol in the treatment of essential hypertension
Synthesis and cardiovascular activity of metoprolol analogues.
Dosage of beta-adrenergic blockers after myocardial infarction.
Inhibitory effects of carvedilol on calcium channels in vascular smooth muscle cells.
Alteration of growth and metabolic activity of cells in the presence of propranolol and metoprolol.
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Comparative pharmacology of human beta-adrenergic receptor subtypes-characterization of stably transfected receptors in CHO cells.
Analysis of urine samples containing cardiovascular drugs by micellar liquid chromatography with fluorimetric detection.
Ablation of postoperative "incisional" reentrant atrial tachycardia and flutter in children using the CARTO system
How Should Subgroup Analyses Affect Clinical Practice? Insights from the Metoprolol Succinate Controlled-Release/Extended-Release Randomized Intervention Trial in Heart Failure (MERIT-HF).
Pheochromocytoma and pregnancy: a case report and review of anesthetic management: Pheochromocytome et grossesse. Expose d'un cas et revue de la demarche anesthesique.
Do beta-blockers prolong survival in heart failure only by inhibiting the beta1-receptor? A perspective on the results of the COMET trial.
In Process Citation
Cost-effectiveness of differing perioperative beta-blockade strategies in vascular surgery patients.
Left ventricular hypertrophy and its reversibility in young spontaneously hypertensive rats.
Effects of thoracic epidural anesthesia and adrenoceptor blockade on the cardiovascular response to dopamine in the dog.
Comparison of the effects of nicardipine and metoprolol on lipid and glycidic metabolism in hypertensive subjects.
Cimetidine: an inhibitor and an inducer of rat liver microsomal cytochrome P-450.
The effect of angiotensin converting enzyme inhibitors (ACE-I) and selective beta 1-antagonists on bronchial reactivity and the cough reflex in man.
The yohimbine-induced anticonflict effect in the rat, Part I. Involvement of noradrenergic, serotonergic and endozepinergic(?) mechanisms.
The rhesus monkey as a model for studies of pregnancy induced changes in metoprolol metabolism.
Plasma levels and effects of metoprolol on blood pressure and heart rate in hypertensive patients after an acute dose and between two doses during long-term treatment.
Effects of metoprolol, alone and in combination with lidocaine, on ventricular fibrillation threshold: comparison with atenolol, propranolol, and pindolol.
Inhibition of purified human postheparin lipoprotein lipase by beta-adrenergic blockers in vitro.
Mechanism of reduced cardiac output during positive end-expiratory pressure in the dog.
Triphasic inotropic response of guinea-pig papillary muscle to murrayaquinone-A isolated from Rutaceae.
Effect of turpentine-induced inflammation on the disposition kinetics of propranolol, metoprolol, and antipyrine in the rat.
Repeated swimming stress and responsiveness of the isolated rat pacemaker to the chronotropic effect of noradrenaline and isoprenaline: role of adrenal corticosteroids.
Interindividual variation of beta-adrenoceptor blocking drugs, plasma concentration and effect: influence of genetic status on behaviour of atenolol, bopindolol and metoprolol.
Osmotically controlled-delivery of metoprolol in man: in vivo performance of Oros systems with different durations of drug release.
Hemodynamic effects of the cardioselective beta-blocking agent metoprolol in acute myocardial infarction. A 24-hour catheterization study.
Beta adrenergic influence on esophageal and colonic motility in man.
Antihypertensive activity of a new vasodilator, cadralazine, administered alone or in combination with a beta-blocker.
Studies on the stereoisomers of beta-adrenoceptor antagonists in conscious A-V blocked dogs.
Effects of long-term antihypertensive treatment and aging on renal function and albumin excretion in primary hypertension.
Beta-adrenergic agonist- and prostaglandin-mediated regulation of cAMP levels in Ewing's sarcoma cells in culture.
Thoracic epidural anesthesia in conscious and anaesthetized rats. Effects on central haemodynamics compared to cardiac beta adrenoceptor and ganglionic blockade.
Effects of atenolol and some other beta-adrenoceptor blocking agents on norepinephrine-induced responses in isolated and perfused rat hearts.
A unique pressor response to isoprenaline in the pithed rat during triiodo-L-thyronine(T3)-induced hyperthyroidism.
The effect of hydralazine on steady-state plasma concentrations of metoprolol in pregnant hypertensive women.
Reduction by acute restraint stress of noradrenaline sensitivity in the isolated pacemaker of the rat.
Analysis of baroreflex control of heart rate in conscious dogs with pacing-induced heart failure.
Comparison of the effects of nine beta-adrenergic blocking agents on intraocular pressure in rabbits.
Effects of sympathetic nerve stimulation in the presence of specific adrenergic antagonists on Na, K, and Cl transport in perfused rat submandibular duct.
Effects of ranitidine on the disposition of metoprolol.
Evaluation of oxprenolol and metoprolol Oros systems in the dog: comparison of in vivo and in vitro drug release, and of drug absorption from duodenal and colonic infusion sites.
Natriuretic and hypertensive activities reside in a fragment of ACTH.
The influence of antihypertensive treatment on the renal arterial structure in spontaneously hypertensive rats. A morphometric study.
Frequency-dependent block of nerve conduction by beta-adrenergic blocking agents.
Relevance of selectivity and non-selectivity in beta-adrenoceptor blocking drugs.
Acute effects of metoprolol on blood pressure and heart rate. Value of the nitroglycerin test
Effects of beta-adrenoceptor agonists and antagonists on thyroid hormone secretion.
Lipophilicity influence on conjunctival drug penetration in the pigmented rabbit: a comparison with corneal penetration.
Haemodynamic consequences of intrinsic sympathomimetic activity and cardioselectivity in beta-blocker therapy for hypertension.
Comparison of metoprolol and propranolol in the treatment of akathisia.
Binding of beta-adrenoceptor antagonists to rat and rabbit lung: special reference to levobunolol.
Evidence, in uremic man, of the role of beta 2 adrenergic receptors in the secretion of parathyroid hormone and calcitonin
Effects of phenoxybenzamine, metoprolol, captopril, and meclofenamate on cardiovascular function in deoxycorticosterone acetate hypertensive Yucatan miniature swine.
Mechanism of protection from atherosclerosis by verapamil in the cholesterol-fed rabbit.
The effect of metoprolol on fenoterol-induced kidney function disorders
Suppression of atrial ectopy with intravenous metoprolol in chronic obstructive pulmonary disease patients.
Long-term medical management of hypertrophic cardiomyopathy: usefulness of propranolol.
Comparison of metoprolol and verapamil in the treatment of angina pectoris.
Influence of the inorganic counterion on the chiral micellar electrokinetic separation of basic drugs using the surfactant N-dodecoxycarbonylvaline.
Cardiac safety of acute beta blockade: intrinsic sympathomimetic activity is superior to beta-1 selectivity.
Metabolic aspects of maximal exercise performance after slow release metoprolol and after atenolol.
Effects of acute and chronic beta-receptor blockade on ventricular repolarisation in man.
Metoprolol kinetics and dose response in hypertensive patients.
Response of the rat heart to catecholamines and thyroid hormones.
Inactivation of constitutive hepatic cytochromes P450 by phencyclidine in the rat.
Beta-adrenoceptor activation stimulates, and phosphodiesterase inhibition potentiates, placental prorenin synthesis and release.
Impact of clinical trials on the use of beta blockers after acute myocardial infarction and its relation to other risk indicators for death and 1-year mortality rate.
Effect of dose of metoprolol on its elimination by isolated perfused rat liver in vitro.
Role of renal nerves for the expression of renin in adult rat kidney.
Synergistic effect of counterregulatory hormones during insulin-induced hypoglycemia in rats: participation of lipolysis and gluconeogenesis to hyperglycemia.
Studies on the antihypertensive effect of metoprolol in practice. Results of a cooperative study by 1296 general practitioners
Contemporary clinical trials in ventricular tachycardia and fibrillation: implications of ESVEM, CASCADE, and CASH for clinical management.
Comparison of nifedipine and metoprolol on collateral coronary blood flow in a swine model of chronic coronary obstruction and acute ischaemia during isoflurane anaesthesia.
Response to beta blockers in patients with neurocardiogenic syncope: how to predict beneficial effects.
Prejunctional beta 1-adrenoceptors inhibit cholinergic transmission in canine bronchi.
Influence of 5-HT1A receptor antagonism on plus-maze behaviour in mice. I. Pindolol enantiomers and pindobind 5-HT1A.
Effects of beta-adrenoceptor blockade on beta-adrenergic signal transduction in cardiomyopathic hamster (BIO 8262) hearts.
Rotating samples in FT-RAMAN spectrometers.
Error structure for the HPLC analysis for atenolol, metoprolol and propranolol: a useful weighting method in parameter estimation.
Comparison of metoprolol and carvedilol pharmacology and cardioprotection in rabbit ischemia and reperfusion model.
Beta-blocker selectivity at cloned human beta 1- and beta 2-adrenergic receptors.
Metoprolol oxidation polymorphism in a Korean population: comparison with native Japanese and Chinese populations.
Ligand binding to the porcine adipose tissue beta-adrenergic receptor.
Adrenergic modulation of potassium metabolism during exercise in normal and diabetic humans.
Regulation of intracellular pH in rabbit cortical connecting tubule and cortical collecting duct.
Effects of various antihypertensive agents on lipid metabolism: alterations in the pattern of lipids synthesized from 14Coleate in rat liver in vitro.
Variability of beta-blocker pharmacokinetics in young volunteers.
The treatment of high blood pressure in the elderly: a multi-centre evaluation of a fixed combination of metoprolol and hydrochlorothiazide ("Co-Betaloc") in general practice.
Comparison of the anti-hypertensive response to beta-adrenoceptor blocking drugs in intact and adrenal-demedullated spontaneously hypertensive rats.
Beta-1 receptor is the predominant beta-adrenoreceptor on rat brown adipose tissue.
Adrenaline activation of prejunctional beta-adrenoceptors and hypertension.
Acute hypotensive effect of combined beta1-adrenoceptor blockade and beta2-adrenoceptor stimulation in spontaneously hypertensive rats (SHR).
Effect of norepinephrine, prenalterol and metoprolol on the histochemical localization of adenylate cyclase activity in the brown adipose tissue of newborn rat.
Additive intraocular pressure reducing effect of topical timolol during systemic beta-blockade.
Variability in the preventive action of the B-blockers on genetic hypertension in the rat.
Effects of lidocaine, procainamide, metoprolol, digoxin and atropine on the conduction of premature ventricular beats in man.
Endothelial prostacyclin production, synergistic effect between adrenergic stimulating and blocking drugs.
Intact cell binding properties of cells expressing altered beta-adrenergic receptors.
Intracoronary infusion of prostaglandin I2 attenuates arterial baroreflex control of heart rate in conscious dogs.
Drug interaction between propafenone and metoprolol.
Does sympathectomy or antihypertensive treatment affect the morphometry of basal cerebral arteries in spontaneously hypertensive rats?
The inhibitory GTP-binding protein (Gi) regulates the agonistic property of beta-adrenergic ligands in isolated rat adipocytes. Evidence for a priming effect of cyclic AMP.
Pharmacokinetic analysis of coronary venous retroinfusion: a comparison with anterograde coronary artery drug administration using metoprolol as a tracer.
Acebutolol, metoprolol and propranolol in conscious dogs with chronic heart-block: chronotropic effects and relation between depression of ventricular activity and beta-adrenoceptor blocking potency.
Membrane stabilizing, anti-oxidative interactions of propranolol and dexpropranolol with neutrophils.
Effect of metoprolol on "non-specific" ST-segment and T-wave changes.
Contractile actions of racemic and d-propranolol on isolated canine mesenteric and coronary arteries.
Involvement of raphe-hippocampal serotonergic and septo-hippocampal cholinergic mechanisms in the penile erection induced by FR121196, a putative cognitive enhancer.
Roles of beta 1- and beta 2-adrenoceptors in the mechanism of halothane myocardial sensitization in dogs.
Predictive value of heart rate in dilated cardiomyopathy treated with metoprolol.
Analysis of the 5-HT1A receptor involvement in passive avoidance in the rat.
Antihypertensive drugs reduce noradrenaline-induced hypertrophy of cultured myocardial cells.
Long-term studies on regression of left ventricular hypertrophy.
Hemodynamic consequences of combined beta-adrenergic and slow calcium channel blockade in man.
Effects of bisoprolol in relation to metoprolol and bufuralol on left ventricular hemodynamics at rest and during exercise in chronic ischemic heart disease.
The force-interval relationship of the left ventricle: a quantitative description in patients with ischemic heart disease.
Vascular smooth muscle relaxation by alpha 1-adrenoceptor blocking action of denopamine in isolated rabbit aorta.
Propranolol has direct antithyroid activity: inhibition of iodide transport in cultured thyroid follicles.
Effect of epinephrine on renal potassium excretion in the isolated perfused rat kidney.
Metoprolol reduces reperfusion-induced fibrillation in the isolated rat heart: protection is secondary to bradycardia.
Endothelial dysfunction in response to psychosocial stress in monkeys.
Effect of beta-blockade on regional left ventricular function in patients with dilated cardiomyopathy.
Adverse drug reaction reporting and retrospective phenotyping for oxidation polymorphism.
Role of P-glycoprotein in restricting propranolol transport in cultured rabbit conjunctival epithelial cell layers.
Plasma catecholamines and cyclic AMP response during head-up tilt test in patients with neurocardiogenic (vasodepressor) syncope.
Hormonal and substrate responses during recovery from hypoglycaemia in man during beta 1-selective and non-selective beta-adrenergic blockade.
Chronic beta-adrenoceptor antagonist treatment modulates human cardiac and vascular beta-adrenoceptor density in a subtype-selective fashion.
On-line detection of reversible myocardial ischemic injury by measurement of myocardial electrical impedance.
Baroreflex control of heart rate and renin release in SHR following administration of felodipine, an antihypertensive Ca2+ antagonist.
The novel 5-HT1A receptor antagonist, SDZ 216-525, decreases 5-HT release in rat hippocampus in vivo.
Beta adrenoceptors of human red blood cells, determination of their subtypes.
Development of a novel drug release system, time-controlled explosion system (TES). I. Concept and design.
Interaction between bile salts and beta-adrenoceptor antagonists.
Influence of the beta-1 selective blocker, metoprolol, on the development of pulmonary edema in tocolytic therapy.
Hypertrophic effect of selective beta(1)-adrenoceptor stimulation on ventricular cardiomyocytes from adult rat.
Dietary obesity and weight cycling in rats: a model of stress-induced hypertension?
Inhibition of lymphocyte capping and transformation by propranolol and related compounds.
The surface activity and self-association of some beta-adrenoceptor blocking agents in aqueous solution.
Liquid chromatographic separation of the enantiomers of metoprolol and its alpha-hydroxy metabolite on Chiralcel OD for determination in plasma and urine.
Transient coronary stenosis associated with arrhythmia and ischemia 24 hours after reperfusion.
Effects of the serotonin-antagonist ketanserin on the function of ischaemic and normally perfused myocardium and modification by beta-1-blockade in anaesthetized normotensive dogs.
The neural control of the serotonin content in mammalian enterochromaffin cells.
Retrospective analysis showing less cardiac events in post-myocardial infarction patients treated with metoprolol. Secondary Prevention Group.
Metabolic actions of a single atenolol and metoprolol dose.
Protein degradation in skeletal muscle during experimental hyperthyroidism in rats and the effect of beta-blocking agents.
The importance of lipid solubility and receptor selectivity of beta-adrenoceptor blocking drugs for the occurrence of symptoms and side-effects in out-patients.
Differential effects of sotalol and metoprolol on induction of paroxysmal supraventricular tachycardia.
Metoprolol metabolism and debrisoquine oxidation polymorphism--population and family studies.
Graded physical loading in assessing the efficacy of hypotensive pharmacotherapy
Participation of beta 2-receptors in the control of rabbit ciliary epithelial permeability.
Conformational structure of some beta 1-blockers, their partitioning in lipid and the role of parasubstituents.
Direct enantioseparation of some beta-adrenergic blocking agents using impregnated thin-layer chromatography.
Quantitation of R- and S-propafenone and of the main metabolite in plasma.
Regioselective and stereoselective oxidation of metoprolol and bufuralol catalyzed by microsomes containing cDNA-expressed human P4502D6.
Influence of alpha stimulants and beta blockers on yohimbine toxicity.
alpha1-adrenergic stimulation induces early afterdepolarizations in ferret Purkinje fibers.
Cardiovascular response to stress: baroreflex resetting and hemodynamics.
Effects of antihypertensive agents propranolol, metoprolol, nadolol, prazosin, and chlorthalidone on ACAT activity in rabbit and rat aortas and on LCAT activity in human plasma in vitro.
Beta-receptor blockade decreases carnitine palmitoyl transferase I activity in dogs with heart failure.
QT interval prolongation in acute myocardial infarction.
beta-Adrenergic receptor subtypes in melanophores of the marine gobies Tridentiger trigonocephalus and Chasmichthys gulosus.
Prophylaxis of supraventricular paroxysmal tachycardias on the basis of electrophysiologic examinations
Reductions in muscle sympathetic nerve activity after long-term metoprolol for dilated cardiomyopathy: preliminary observations.
Cardiovascular and sympathoadrenal responses to intrathecal injection of neuropeptide K in the conscious rat.
Hemodynamic and reflex sympathetic control of transmural activation and rate of ventricular tachycardia in ischemic and hypertrophic ventricular myocardium of the dog.
Malignant vasovagal syncope: its diagnosis and therapeutic trial based on the orthostatism test (the tilt-table test)
Inhibition of 3H-dihydroalprenolol binding to rat cardiac membranes of various beta-blocking agents.
Influence of topical and systemic beta-blockers on tear production.
Effect of acute cardiac tamponade on left ventricular pressure-volume relations in anaesthetised dogs.
Utility of a transdermal delivery system for antihypertensive therapy. Part 1.
Limitations of the stress test in the diagnosis of the sick sinus syndrome
Pharmacological evidence that alpha 1-adrenoceptors mediate metamorphosis of the Pacific oyster, Crassostrea gigas.
Cardiovascular effects of theophylline. Partial attenuation by beta-blockade.
Effects of metoprolol on the peripheral circulation in patients with peripheral vascular disease
Effect of antiarrhythmic therapy on delayed potentials detected by the signal-averaged electrocardiogram in patients with ventricular tachycardia after acute myocardial infarction.
Beta adrenoceptors mediate the catecholamine-induced stimulation of oxytocin secretion from cultured bovine granulosa cells.
Pharmacological basis for the therapy of cardiovascular disease with beta-adrenoceptor blocking drugs
Coronary reperfusion by thrombolysis and early beta-adrenergic blockade in acute experimental myocardial infarction.
The cardiac hazard of tocolysis and antagonising possibilities. I. The haemodynamic situation of the patient during tocolysis/Protection of the myocardium by means of cardioselective beta-blockade. Experimental results
Migraine and beta blocker. An overview
Increased beta-receptor density and improved hemodynamic response to catecholamine stimulation during long-term metoprolol therapy in heart failure from dilated cardiomyopathy.
Goteborg Metoprolol Trial: tolerance.
Dopexamine hydrochloride in the human heart: receptor binding and effects on cAMP generation.
The molecular mechanisms of two common polymorphisms of drug oxidation--evidence for functional changes in cytochrome P-450 isozymes catalysing bufuralol and mephenytoin oxidation.
Inhibition by metoprolol of the antihypertensive effect of aspirin in young rats.
The adrenergic contribution to glucose counterregulation in type I diabetes mellitus. Dependency on A-cell function and mediation through beta 2-adrenergic receptors.
Comparison of the effect of the beta1-blocking drugs atenolol and metoprolol on bronchial asthma.
Effects of antihypertensive therapy on blood pressure and renal function in rats with hypertension due to chronic blockade of nitric oxide synthesis.
Protection by beta-blocking agents against free radical-mediated sarcolemmal lipid peroxidation.
Usefulness of transesophageal electrophysiological study during the ergometric test in the evaluation of supraventricular paroxysmal tachycardia occurring during exertion
Keratinized epithelial transport of beta-blocking agents. II. Evaluation of barrier property of stratum corneum by using model lipid systems.
Formation of the N-nitroso derivatives of six beta-adrenergic-blocking agents and their genotoxic effects in rat and human hepatocytes.
Chronic beta-blockade transregulates inhibitory A1 adenosine and muscarinic M2 receptors of the adenylyl cyclase system.
Smoking, antihypertensive treatment benefit, and comprehensive antihypertensive treatment approach: some thoughts on the results of the International Prospective Primary Prevention Study in Hypertension.
Differential effects of triiodothyronine on rat left and right ventricular function and the influence of metoprolol.
Effect of antihypertensive treatment on progression of incipient diabetic nephropathy.
Binding characteristics of 3H-CGP12177 to beta-adrenoceptors in rat myocardial membranes.
Adrenergic mechanisms underlying cardiac and vascular responses to cocaine in conscious rats.
Subtype-selective up-regulation of human saphenous vein beta 2-adrenoceptors by chronic beta-adrenoceptor antagonist treatment.
Determination of variability factors of arterial pressure using 3843 self-measurements of blood pressure in 34 active hypertensives
Relative potencies of various beta-adrenoceptor antagonists (BAA) at the level of the human myocardial beta-adrenoceptor-adenylate cyclase (AC) complex. Is intrinsic sympathomimetic activity (ISA) due to AC activation?
Role of adrenoceptors in vasopressin, oxytocin and prolactin responses to conditioned fear stimuli in the rat.
Inhibition of desmethylimipramine 2-hydroxylation by drugs in human liver microsomes.
Regression of left ventricular hypertrophy in hypertensive patients: responses to exercise by antihypertensive treatment.
Reperfusion-induced ventricular fibrillation. Modification by pharmacological agents.
Measurement of left ventricular maximal isovolumetric pressure in rats: effects of antihypertensive drugs and diabetes mellitus.
Autonomic control of ventricular tachycardia: direct effects of beta-adrenergic blockade in 24 hour old canine myocardial infarction.
Low clastogenic activity in vivo of the N-nitroso derivatives of 5 beta-adrenergic-blocking drugs proved to be potent genotoxins in vitro.
Homogeneous class of beta-1 adrenergic receptors in rat kidney. Identification by (+/-)-125 iodocyanopindolol binding.
Which subgroup of patients with dilated cardiomyopathy would benefit from long-term beta-blocker therapy? A histologic viewpoint.
Can beta-blocker therapy be withdrawn from patients with dilated cardiomyopathy?
Effects of the (+/-)-, (+)- and (-)-forms of propranolol, timolol and metoprolol on noradrenergic transmission in the rat isolated right ventricle.
Hemodynamic effects of once a day administration of combined chlorthalidone and metoprolol slow-release in essential hypertension.
Dissolution profile determination of a multicomponent product using a rapid liquid chromatographic analysis.
Metoprolol pharmacokinetics and the oral contraceptive pill.
Glibenclamide, a blocker of ATP-sensitive potassium channels, abolishes infarct size limitation by preconditioning in rabbits anesthetized with xylazine/pentobarbital but not with pentobarbital alone.
Effects of beta-blockade on atrial and atrioventricular nodal refractoriness, and atrial fibrillatory rate during atrial fibrillation in pigs.
Cardiodepressant mediators are released after myocardial ischaemia: modulation by catecholamines and adenosine.
Alterations in the arrhythmogenic dose of epinephrine after adrenergic receptor blockade with prazosin, metoprolol, or yohimbine in halothane-xylazine-anesthetized dogs.
Novel 'soft' beta-blockers as potential safe antiglaucoma agents.
Evidence that aspartic acid 301 is a critical substrate-contact residue in the active site of cytochrome P450 2D6.
Polymorphic debrisoquine 4-hydroxylase activity in the rat is due to differences in CYP2D2 expression.
Effects of propranolol on atherogenesis in the cholesterol-fed rabbit.
Use of 4-(N,N-dimethylaminosulphonyl)-7-fluoro-2,1,3-benzoxadiazole as a labelling reagent for peroxyoxalate chemiluminescence detection and its application to the determination of the beta-blocker metoprolol in serum by high-performance liquid chromatography.
Enantioselective determination of metoprolol in plasma by liquid chromatography on a silica-bonded alpha 1-acid glycoprotein column.
Heart rate-dependent atrioventricular nodal conduction and the effects of calcium channel blocking drugs: comparison of verapamil and nifedipine.
Characterization and autoradiographic distribution of the beta-adrenergic receptor in the rat lung.
Interaction studies of 5-HT1A receptor antagonists and selective 5-HT reuptake inhibitors in isolated aggressive mice.
Within-patient comparisons between different anti-hypertensive drugs.
Coexistence of beta 1- and beta 2-adrenoceptors in the melanophore of the goby Tridentiger obscurus.
Evidence for a stimulatory beta-adrenergic component in the release of the ovulatory LH surge in pro-oestrous rats.
Acute poisoning caused by beta blockers in the adult. Apropos of 7 cases
Coexistence of beta 1- and beta 2-adrenoceptors in the rabbit heart: quantitative analysis of the regional distribution by (-)-3H-dihydroalprenolol binding.
Denopamine, a beta1-adrenergic agonist, prolongs survival in a murine model of congestive heart failure induced by viral myocarditis: suppression of tumor necrosis factor-alpha production in the heart.
Existence of a beta3-adrenoceptro and its functional role in the human ureter.
Pharmacology of dextroamphetamine-induced cardiovascular malformations in the chick embryo.
Binding properties of beta-adrenergic receptors in early human fetal lung.
Pressor effect of beta-adrenergic receptor blocking drugs in spontaneously hypertensive rats treated with clonidine.
The effect of beta-adrenergic blockade in dilated cardiomyopathy--a questionnaire study in Japan.
Synthesis and beta-adrenergic antagonist activity of heterocyclic propanolamines.
The human heart beta-adrenergic receptors. II. Coupling of beta 2-adrenergic receptors with the adenylate cyclase system.
Investigation of drug absorption from the gastrointestinal tract of man. II. Metoprolol in the jejunum and ileum.
The effects of beta-adrenoceptor antagonists and levomepromazine on the metabolic ratio of debrisoquine.
Investigation of drug absorption from the gastrointestinal tract of man. III. Metoprolol in the colon.
The effect of beta-adrenoceptor blocking agents on evolving myocardial necrosis in coronary ligated rats with and without reperfusion.
Investigation of drug absorption from the gastrointestinal tract of man. IV. Influence of food and digestive secretions on metoprolol jejunal absorption.
Enantioselective and diastereoselective aspects of the oxidative metabolism of metoprolol.
Metoprolol--a new cardioselective beta-adrenoceptor blocking agent for treatment of tachyarrhythmias.
The effect of beta-adrenoceptor antagonists on the pharmacokinetics and pharmacodynamics of warfarin after a single dose.
The absorption of beta-adrenoceptor antagonists in rat in-situ small intestine; the effect of lipophilicity.
Nature of the beta-adrenoreceptors in the tracheal smooth muscle of the adult pig.
Presence of beta-adrenoreceptors in the hypothalamus; their importance for the pressor response to hypothalamic stimulation.
Doping control for beta-adrenergic compounds through hair analysis.
The actions of the beta-adrenoceptor blocking agents propranolol and metoprolol in the maximally exercised horse.
Effect of an acute beta-adrenergic blockade on the relationship between ventilatory and plasma lactate threshold.
Effects of selected beta-adrenergic blocking agents on sleep stages in spontaneously hypertensive rats.
Characterization of beta-adrenergic receptor subtypes in androgen-induced mouse kidney hypertrophy using a new high-affinity ligand, 125Iiodocyanopindolol.
Effects of selective beta-adrenoceptor antagonists on gastric ulceration in the rat.
Protective effects of different beta-blocking agents against electroshock lethality in mice.
No functional atypical beta-adrenergic receptors in human omental adipocytes.
Determination of beta-blocker drugs in pharmaceutical preparations by non-suppressed ion chromatography.
Out-patient use of beta-blocking agents--prescribing preferences of physicians in training.
Soft drugs. 7. Soft beta-blockers for systemic and ophthalmic use.
Inhibition of aconitine-induced mortality in the conscious rat: a screening test for antiarrhythmic drugs.
Determination of some beta-blockers as dabsyl derivatives by HPLC.
Protective effects of beta-blockers against 2,2'-azobis(2-amidinopropane)-dihydrochloride-induced damage.
A preliminary study of beta-cyclodextrin/metoprolol tartrate inclusion complex for potential enantiomeric separation.
Effect of the sympathetic activation and its inhibition on left ventricular mechanics in mitral prolapse. Echocardiographic study in 35 patients
Pre- and postjunctional beta-adrenoceptor mediated effects on transmitter release and effector response in the isolated rat portal vein.
Acute effects of dihydralazine mesylate, furosemide, and metoprolol on maternal hemodynamics in pregnancy-induced hypertension.
Characterization of the beta-adrenergic inhibition of motility in cat colon strips.
Hemodynamic responses to beta-adrenergic blockade with metoprolol and pindolol after coronary artery bypass surgery.
A sustained increase in beta-adrenoceptors during long-term therapy with metoprolol and bisoprolol in patients with heart failure from idiopathic dilated cardiomyopathy.
Changes in lymphocyte beta-receptor density in patients with heart failure before and after metoprolol or captopril administration
The effect of beta-stimulation and beta-1-blockade on the motility of the upper urinary tract
Evidence that an atypical beta-adrenoceptor mediates the prejunctional inhibition of non-adrenergic non-cholinergic contraction in guinea-pig bronchi.
Plasma insulin levels and beta-adrenoceptor antagonists. The effects of cardioselective and non-cardioselective beta-adrenoceptor antagonists with and without intrinsic sympathomimetic activity on basal insulin level and insulin level after glucose stimulation in normoglycemic dogs.
Polymorphic metabolism of beta-adrenoceptor antagonists.
Enantioselective assay of beta-receptor antagonists present in microdialysis and plasma samples of rats.
Transport of celiprolol across human intestinal epithelial (Caco-2) cells: mediation of secretion by multiple transporters including P-glycoprotein.
Beta-1 and beta-2 adrenoceptors mediate smooth muscle relaxation in bovine isolated mesenteric lymphatics.
Food-induced reduction in bioavailability of atenolol.
Pharmacodynamic profile of bisoprolol, a new beta 1-selective adrenoceptor antagonist.
Effects of autonomic blockade on cardiac function at rest and during upright exercise in humans.
Local beta-adrenergic blockade does not reduce infarct size after coronary occlusion and reperfusion: a study of coronary venous retroinfusion of metoprolol.