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  • Chronic alpha-1-adrenergic blockade increases sympathoneural but not adrenomedullary activity in patients with essential hypertension.
  • Modulation of tumor necrosis factor-alpha production with anti-hypertensive drugs.
  • Long-term effects of a selective alpha 1-adrenergic inhibitor on right and left ventricular masses in patients with chronic pulmonary disease
  • Effects of spinal alpha 1-adrenoceptor antagonism on bladder activity induced by apomorphine in conscious rats with and without bladder outlet obstruction.
  • Comparative alpha-1 adrenoceptor subtype selectivity and functional uroselectivity of alpha-1 adrenoceptor antagonists.
  • Pharmacology of tamsulosin: saturation-binding isotherms and competition analysis using cloned alpha 1-adrenergic receptor subtypes.
  • Transforming growth factor beta 1 transduced mouse prostate reconstitutions: II. Induction of apoptosis by doxazosin.
  • Effect of doxazosin on endothelial dysfunction in hypercholesterolemic/antioxidant-deficient rats.
  • The treatment of benign prostatic hyperplasia with alpha blockers in men over the age of 80 years.
  • Effect of antihypertensive treatment with doxazosin on insulin sensitivity and fibrinolytic parameters.
  • Voltammetric determination of doxazosin in tablets using rotating platinum electrode.
  • Central pressor effect of parathyroid hormone-related protein in conscious rats.
  • Correction of neurovascular deficits in diabetic rats by beta2-adrenoceptor agonist and alpha1-adrenoceptor antagonist treatment: interactions with the nitric oxide system.
  • Induction of prostate apoptosis by doxazosin in benign prostatic hyperplasia.
  • Effects of doxazosin and hydralazine on insulin sensitivity and sympathetic function in spontaneously hypertensive rat (SHR)
  • Effects of antihypertensive drugs on autoregulation of RBF and glomerular capillary pressure in SHR.
  • Cardiac endothelin-1 plays a critical role in the functional deterioration of left ventricles during the transition from compensatory hypertrophy to congestive heart failure in salt-sensitive hypertensive rats.
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  • Reduction of human prostate tumor vascularity by the alpha1-adrenoceptor antagonist terazosin.
  • Low-dose ACE with alpha- or beta-adrenergic receptor inhibitors have beneficial SHR cardiovascular effects.
  • Efficacy and tolerability of drugs for treatment of benign prostatic hyperplasia.
  • Relationship between arterial distensibility and low-frequency power spectrum of blood pressure in spontaneously hypertensive rats.
  • alpha1-adrenergic receptor activation of c-fos expression in transfected rat-1 fibroblasts: role of Ca2+.
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  • Quinazoline-derived alpha1-adrenoceptor antagonists induce prostate cancer cell apoptosis via an alpha1-adrenoceptor-independent action.
  • Pharmacotherapy in congestive heart failure. Prematurely terminated clinical trials and their application to cardiovascular medicine.
  • Interaction of digoxin with antihypertensive drugs via MDR1.
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  • Doxazosin, of modified liberation, in hemodialyzed patients
  • alpha1-Adrenergic blockers in young men with primary bladder neck obstruction.
  • Alpha1-adrenoceptor antagonists radiosensitize prostate cancer cells via apoptosis induction.
  • Hypertension and metabolic syndrome in population of one company. Monotherapy with amlodipine and doxazosin
  • Stromal/epithelial interactions of murine prostatic cell lines in vivo: a model for benign prostatic hyperplasia and the effect of doxazosin on tissue size.
  • Doxazosin treatment and peroxidation of low-density lipoprotein among male hypertensive subjects: in vitro and ex vivo studies.
  • Morning vs evening dosing with doxazosin in benign prostatic hyperplasia: efficacy and safety.
  • Doxazosin induces apoptosis in cardiomyocytes cultured in vitro by a mechanism that is independent of alpha1-adrenergic blockade.
  • Tonocardin in complex treatment of diabetes mellitus concurrent with hypertension
  • The ICH guidance in practice: stress decomposition studies on three piperazinyl quinazoline adrenergic receptor-blocking agents and comparison of their degradation behaviour.
  • Effects of alpha1-adrenoceptor antagonists on cultured prostatic smooth muscle cells.
  • Quinazoline-based alpha 1-adrenoceptor antagonists induce prostate cancer cell apoptosis via TGF-beta signalling and I kappa B alpha induction.
  • Tonocardin (doxazosin) in treating lower urinary tract symptoms
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  • Diuretic versus alpha-blocker as first-step antihypertensive therapy: final results from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).
  • A study of the interaction between the hypotensive actions of doxazosin and enalaprilat in anaesthetized rats.
  • Dose-related effects of doxazosin on plasma lipids and aortic fatty streak formation in the hypercholesterolemic hamster model.
  • Compliance and reactivity of the peripheral venous system in chronic intermittent hemodialysis.
  • Alpha-adrenergic vasoconstriction in normal and hypoperfused myocardium during sympathetic nerve stimulation.
  • Flow cytometric analysis of platelet activation in hypertensive patients. Effect of doxazosin.
  • Doxazosin, an alpha-1 antagonist, prevents further progression of the advanced atherosclerotic lesion in hypercholesterolemic hamsters.
  • The psychological effects of treatments for lower urinary tract symptoms.
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  • Validated specific HPLC methods for determination of prazosin, terazosin and doxazosin in the presence of degradation products formed under ICH-recommended stress conditions.
  • Prostate apoptosis after doxazosin treatment in the spontaneous hypertensive rat model.
  • Herbal and vitamin supplement use in a prostate cancer screening population.
  • Alpha-1 blockade inhibits compensatory sodium reabsorption in the proximal tubules during furosemide-induced volume contraction.
  • The effect of doxazosin, urapidil and indoramin pretreatment on fever produced by E. coli lipopolysaccharide in rabbits.
  • A norepinephrine-dependent mechanism in the preoptic/anterior hypothalamic area but not in the mediobasal hypothalamus is involved in the regulation of the gonadotropin-releasing hormone pulse generator in ovariectomized rats.
  • Blood flow regulation during acute regional ischemia in feline hearts: importance of postjunctional alpha 1- and alpha 2-adrenoceptors.
  • The effect of doxazosin on blood pressure, lipids, fibrinogen and plasminogen activator inhibitor. A comparative study among smokers and non-smokers with essential hypertension
  • Subtype selective alpha1-adrenoceptor antagonists for the treatment of benign prostatic hyperplasia.
  • The initial hemodynamic response to newer antihypertensive agents at rest and during exercise: review of visacor, doxazosin, nisoldipine, tiapamil, perindoprilat, pinacidil, dilevalol, and carvedilol.
  • Selective alpha 1 inhibition with doxazosin in hypertensive smokers and non-smokers: haemodynamic and metabolic effects.
  • Doxazosin in renal impairment.
  • In vivo and in vitro studies of alpha 2-adrenoceptor responses in human vascular smooth muscle.
  • Antihypertensive effects and pharmacokinetics of single and consecutive administration of doxazosin in patients with mild to moderate essential hypertension.
  • Effects of alpha 1-inhibition on lipid metabolism in the rat.
  • Effect of doxazosin on cholesterol synthesis in cell culture.
  • Interactions of doxazosin with insulin or glucagon in the ob/ob mouse.
  • Regulation of triglyceride mobilization in isolated hepatocytes by dibutyryl cyclic AMP and epinephrine.
  • Adrenoceptors in Raynaud's disease.
  • Safety, efficacy, and lipid profile of doxazosin at a VA medical center.
  • Delayed recovery of homogeneous perfusion distribution in isolated rat heart after vasodilatation induced by alpha 1 adrenoceptor blockade during postischaemic reperfusion.
  • An in vitro study of interactions between doxazosin and enalaprilat at vascular alpha 1-adrenoceptors.
  • Doxazosin, a new alpha-1-antagonist drug, controls hypertension without causing airways obstruction in asthma and COPD.
  • Differences between exogenous and endogenous noradrenaline in the effects on vascular post-synaptic alpha 1- and alpha 2-adrenoceptors in man.
  • Pharmacokinetic and pharmacodynamic studies with two alpha-adrenoceptor antagonists, doxazosin and prazosin in the rabbit.
  • Clinical pharmacological studies with doxazosin.
  • 2,4-diamino-6,7-dimethoxyquinazolines. 1. 2-4-(1,4-benzodioxan-2-ylcarbonyl)piperazin-1-yl derivatives as alpha 1-adrenoceptor antagonists and antihypertensive agents.
  • Role of alpha 1- and alpha 2-adrenergic receptors in the human hypertensive kidney.
  • Pharmacokinetic and pharmacodynamic modelling of the alpha adrenoceptor antagonist doxazosin.
  • Clinical experience with doxazosin in general medical practice.
  • pH-mediated field-amplified sample stacking of pharmaceutical cations in high-ionic strength samples.
  • Doxazosin in the treatment of patients with mild or moderate hypertension and mild or moderate renal insufficiency.
  • A single-blind study of doxazosin in the treatment of essential hypertension when added to nonresponders to angiotensin-converting enzyme inhibitor therapy.
  • Haemodynamic effects of new beta-blockers with vasodilatory properties in essential hypertension.
  • Acute renal effects of doxazosin in man.
  • The pharmacokinetics of doxazosin in elderly normotensives.
  • Size and site-dependent heterogeneity of human vascular responses in vitro.
  • Effects of exogenous adrenaline and noradrenaline on vascular postsynaptic alpha 1- and alpha 2-adrenoceptors in man.
  • Identification of vascular postsynaptic alpha 1- and alpha 2-adrenoceptors in man.
  • Efficacy and safety of the alpha-1 blocker doxazosin in the treatment of benign prostatic hyperplasia. Analysis of 5 studies. Doxazosin Study Groups.
  • Characterization of human recombinant alpha(2A)-adrenoceptors expressed in Chinese hamster lung cells using intracellular Ca(2+) changes: evidence for cross-talk between recombinant alpha(2A)- and native alpha(1)-adrenoceptors.
  • The impact of 5-alpha-reductase inhibitors on the number of prostatectomies for benign prostatic hyperplasia.
  • Characterization of an alpha 1D-adrenoceptor mediating the contractile response of rat aorta to noradrenaline.
  • Hypertension, diabetes mellitus, atherosclerosis: clinical manifestations of metabolic syndrome X. Prospects of pharmacological treatment
  • Functional tolerance to alpha-adrenergic receptor blockade in the spontaneously hypertensive rat highlights the multifunctional role of vascular angiotensin II in the development of hypertension.
  • Endogenous adenosine attenuates myocardial stunning by antiadrenergic effects exerted during ischemia and not during reperfusion.
  • Efficacy and tolerance of doxazosin in the treatment of isolated systolic hypertension in hypertensive patients over 60 years of age
  • Influence of alpha-receptor blockade on the time-dependent change in the effect of furosemide.
  • Prevention by specific chemical classes of alpha 1-adrenoceptor antagonists of veratrine-contractures in rat left atria independently of alpha 1-adrenoceptor blockade.
  • Selective alpha 1-adrenergic inhibition improves decrease glucose disposal in patients with essential hypertension.
  • Changes in glucose, insulin, lipid, lipoprotein, and apoprotein concentrations and insulin action in doxazosin-treated patients with hypertension. Comparison between nondiabetic individuals and patients with non-insulin-dependent diabetes mellitus.
  • Effect of three antihypertensive drug groups on lipid metabolism. Effects of alpha receptor blockers, central sympatholytic drugs and vasodilators
  • Alpha-blocker therapy for benign prostatic hyperplasia: a comparative review.
  • Inhibition of low density lipoprotein oxidation in vitro by the 6- and 7-hydroxy-metabolites of doxazosin, an alpha 1-adrenergic antihypertensive agent.
  • Doxazosin improves insulin sensitivity in hypertensive patients.
  • Doxazosin withdrawal and ambulatory blood pressure monitoring in normotensive subjects.
  • Effects of doxazosin on atherosclerosis in cholesterol-fed rabbits.
  • The alpha 1-adrenoceptor antagonist, doxazosin, modulates the lower limit of autoregulation of cerebral blood flow during hemorrhagic hypotension in anesthetized hypertensive rats.
  • Doxazosin blocks the angiotensin II-induced smooth muscle cell DNA synthesis in the media, but not in the neointima of the rat carotid artery after balloon injury.
  • Effects of antihypertensive drugs on nitric oxide synthase activity in rat kidney.
  • Contribution of local renin-angiotensin system to cardiac hypertrophy, phenotypic modulation, and remodeling in TGR (mRen2)27 transgenic rats.
  • Effect of doxazosin on fibrinolysis in hypertensive patients with and without insulin resistance.
  • Micturition in conscious rats with and without bladder outlet obstruction: role of spinal alpha 1-adrenoceptors.
  • The release of the substrate for xanthine oxidase in hypertensive patients was suppressed by angiotensin converting enzyme inhibitors and alpha1-blockers.







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