Drugs online research references
Antinidatory effect of luteal phase administration of mifepristone (RU486) is associated with changes in endometrial prostaglandins during the implantation window.
Prostaglandin E2 from macrophages of murine splenocyte cultures inhibits the generation of lymphokine-activated killer cell activity.
Nocturnal enuresis as a manifestation of autocoidosis
The ex vivo measurement of malondialdehyde and chemiluminescence as possible indices for anti-inflammatory drug evaluation.
Signal transduction mechanisms in substance P-mediated ciliostimulation.
Dual signal transduction mechanisms modulate ciliary beat frequency in upper airway epithelium.
Pharmacokinetics and metabolism of diclofenac sodium in Yucatan miniature pigs.
Pharmacokinetics and metabolism of N-(2-hydroxyethyl)-2,5-14C-pyrrolidine (HEP, Epolamine) in male healthy volunteers.
Effects on intestinal microflora, gastrointestinal tolerability and antiinflammatory efficacy of diclofenac and nitrofenac in adjuvant arthritic rats.
Intracerebroventricular micro-injections of non-steroidal anti-inflammatory drugs abolish reperfusion hyperalgesia in the rat's tail.
In vitro forecasting of drugs that may interfere with codeine bioactivation.
Role of human liver microsomal CYP2C9 in the biotransformation of lornoxicam.
Pharmacokinetics of misoprostol in the elderly, in patients with renal failure and when coadministered with NSAID or antipyrine, propranolol or diazepam.
Beta-blockers inhibit the modification of low-density lipoproteins by sodium hypochlorite in vitro.
Combined effect of cyclic monoterpenes and ethanol on percutaneous absorption of diclofenac sodium.
Cytochrome P450 expression and related metabolism in human buccal mucosa.
Luteolytic action of RU486: modulation of luteal 3 beta-hydroxysteroid dehydrogenase and 20 alpha-hydroxysteroid dehydrogenase activities in late pregnant rats.
Adaptation of rat gastric mucosa to repeated doses of non-salicylate non-steroidal anti-inflammatory drugs.
Interaction of myeloperoxidase with diclofenac. Inhibition of the chlorinating activity of myeloperoxidase by diclofenac and oxidation of diclofenac to dihydroxyazobenzene by myeloperoxidase.
N-acetyl-beta-D-glucosaminidase enzymuria as an indicator in monitoring the therapy of some rheumatic diseases with potentially nephrotoxic drugs.
Self assembling nanostructures for sustained ophthalmic drug delivery.
Determinants of placental drug transfer: studies in the isolated perfused human placenta.
Pharmacology of the potent new non-steroidal anti-inflammatory agent aceclofenac.
Prevention of in vitro neutrophil-endothelial attachment through shedding of L-selectin by nonsteroidal antiinflammatory drugs.
Economic comparison of nimesulide and diclofenac, and the incidence of adverse events in the treatment of rheumatic disease in Greece.
Inhibition of inducible nitric oxide synthase expression by novel nonsteroidal anti-inflammatory derivatives with gastrointestinal-sparing properties.
Bradyzide, a potent non-peptide B(2) bradykinin receptor antagonist with long-lasting oral activity in animal models of inflammatory hyperalgesia.
A new test for evaluating nonsteroidal anti-inflammatory drugs in vitro: inhibition of prostaglandin E2 production in minced intestinal tissue.
In vivo phototoxicity of non-steroidal anti-inflammatory drugs evaluated by the mouse tail technique.
Rectal administration of nonsteroidal antiinflammatory drugs. Effect on rat gastric ulcerogenicity and prostaglandin E2 synthesis.
A nitric oxide-releasing nonsteroidal anti-inflammatory drug accelerates gastric ulcer healing in rats.
In vivo selectivity of nonsteroidal antiinflammatory drugs and gastrointestinal ulcers in rats.
Differential inhibitory effects of phenytoin, diclofenac, phenylbutazone and a series of sulfonamides on hepatic cytochrome P4502C activity in vitro, and correlation with some molecular descriptors in the dwarf goat (Caprus hircus aegagrus).
Assessment of topical non-steroidal anti-inflammatory drugs in animal models.
Influence of various non-steroid antirheumatic drugs on the electric potential between the gastric serosa and mucosa
The activity of non-steroidal anti-inflammatory drugs in the rat mesenteric vasculature.
Impact of NSAIDS on murine antigen induced arthritis. I. Investigation of antiinflammatory and chondroprotective effects.
Phototoxicity of non-steroidal anti-inflammatory drugs: in vitro studies with visible light.
Nepafenac, a unique nonsteroidal prodrug with potential utility in the treatment of trauma-induced ocular inflammation: I. Assessment of anti-inflammatory efficacy.
Effects of systemic non-steroidal anti-inflammatory drugs on nociception during tail ischaemia and on reperfusion hyperalgesia in rats.
The determination of non-steroidal anti-inflammatory drugs by GC-MS-MS in equine urine.
Protein binding of some nonsteroidal anti-inflammatory drugs studied by high-performance liquid affinity chromatography.
Biliary elimination of non-steroidal anti-inflammatory drugs in patients.
Antifibroproliferative effect of tenidap in chronic antigen-induced arthritis.
Differential effects of nonsteroidal anti-inflammatory drugs on constitutive and inducible prostaglandin G/H synthase in cultured bone cells.
Antinociceptive effects of non-steroidal anti-inflammatory drugs in a rat model of unilateral hindpaw inflammation.
Influence of standard and novel LTB4 analogs on human neutrophil chemotaxis measured by the multiwell cap assay.
Comparison of the effect of nonsteroidal and steroidal antiinflammatory agents on prostaglandin production during ovulation in the rabbit.
The biotransformation of NSAIDs: a common elimination site and drug interactions
Prescribed medication and nutrition of social care patients in Crete, Greece.
Anti-inflammatory activity of 2-acyl-5(3)-hydroxytetrahydro-1H-pyrazole derivatives.
A new method for assaying anti-inflammatory drugs. Quantitative analysis of pigment leakage into skin by Chromatoscanner CS-900
Formulation and evaluation of Methocel K15M bioadhesive matrix tablets.
Non-competitive inhibition of GABAA responses by a new class of quinolones and non-steroidal anti-inflammatories in dissociated frog sensory neurones.
Comparative analgesic efficacy of nimesulide and diclofenac gels after topical application on the skin.
HPLC-determination of some antiinflammatory, weak analgesic and uricosuric drugs in human blood plasma and its application to pharmacokinetics.
Evidence for the existence of a specific binding site for indomethacin on bovine vesicular gland microsomes.
Simultaneous determination of diclofenac sodium and its hydroxy metabolites by capillary column gas chromatography with electron-capture detection.
Development and evaluation of controlled-release diclofenac microspheres and tabletted microspheres.
Mechanisms involved in the antiinflammatory effect of propolis extract.
Anti-implantation activity of luteal phase mifepristone administration is not mimicked by prostaglandin synthesis inhibitor or prostaglandin analogue in the rhesus monkey.
Simultaneous determination of diclofenac and oxybuprocaine in human aqueous humor with HPLC and electrochemical detection.
Crocheted ETFE-reactor for on-line post-column photoderivatization of diclofenac in high-performance liquid chromatography.
The ocular pharmacokinetics of topical diclofenac is affected by ocular inflammation.
An experimental validation of the combined use of dimephosphon with nonsteroidal anti-inflammatory preparations
Mechanisms involved in the effects of phenidone, diclofenac and ethacrynic acid in rat uterus in vitro.
Comparative bioavailability of slow release diclofenac (Voveran SR) with enteric coated tablet and internationally used Voltaren Retard.
Influence of non-steroidal anti-inflammatory drugs on the binding kinetics of dansylsarcosine to human serum albumin. Stereoselectivity, steric and inductive effects.
Drug and fatty acid effects on serum thyroid hormone binding.
Action of diclofenac sodium on the reparation process of the surgically-perforated myometrium of pregnant albino rats: morphological and morphometrical evaluation.
Influence of pentobarbitone on in-vivo local disposition of diclofenac in rat liver.
Role of the epithelium in opposing H(2)O(2)-induced modulation of acetylcholine-induced contractions in rabbit intrapulmonary bronchiole.
Testing drugs on human osteoarthritic articular cartilage.
Modulation of murine osteoarthritis.
Institute of Rheumatology and progress of antirheumatic therapy
Inhibition of cytochrome P450 2C9 activity in vitro by 5-hydroxytryptamine and adrenaline.
The structural and electronical factors that contribute affinity for the time-dependent inhibition of PGHS-1 by indomethacin, diclofenac and fenamates.
Failure of calcium antagonistic agents to prevent hepatotoxicity induced by diclofenac.
Pharmacokinetics of paracetamol, diclofenac and vidarabine during plasma exchange.
Determination of liposome partitioning of ionizable drugs by titration.
Examination of metabolic pathways and identification of human liver cytochrome P450 isozymes responsible for the metabolism of barnidipine, a calcium channel blocker.
HCO3- reduces paracellular permeability of guinea pig duodenal mucosa by a Ca2+ (prostaglandin)-dependent action.
Variation in the risk of peptic ulcer complications with nonsteroidal antiinflammatory drug therapy.
Simulation of skin permeability in chitosan membranes.
Protection against peroxynitrite dependent tyrosine nitration and alpha 1-antiproteinase inactivation by some anti-inflammatory drugs and by the antibiotic tetracycline.
Metabolism of 5(6)Oxidoeicosatrienoic acid by ram seminal vesicles. Formation of two stereoisomers of 5-hydroxyprostaglandin I1.
Plasma concentrations and pharmacokinetic parameters of nitrofenac using a simple and sensitive HPLC method.
Headache treatment in an emergency unit of the city of Ribeirao Preto, Brazil
Effects of three antiarthritic drugs on fibronectin and keratan sulfate synthesis by cultured canine articular cartilage chondrocytes.
Local tolerability and pharmacokinetic profile of a new transdermal delivery system, diclofenac hydroxyethylpyrrolidine plaster.
Comparative biochemical pharmacology of the oxicams.
Synthesis and physico-chemical properties of lonazolac-Ca, a new antiphlogistic/antirheumatic agent
Effects of the antihypertensive agent, cicletanine, on noradrenaline release and vasoconstriction in perfused mesenteric artery of SHR.
Interaction between blood platelets and capillary kidney in haemodialysis
Effects of diclofenac sodium and He:Ne laser irradiation on plasmatic fibrinogen levels in inflammatory processes.
Is monochromatic irradiation testing useful in the differentiation of drug-induced photosensitivity from chronic actinic dermatitis?
In vitro topical delivery of non-steroidal anti-inflammatory drugs through human skin.
Renal dysfunction associated with the perioperative use of diclofenac.
Characterization of endothelin-1-induced vascular effects in the rat heart by using endothelin receptor antagonists.
Influence of the formulation on the in vitro transdermal penetration of sodium diclofenac. Evaluation of the topical and systemic anti-inflammatory activity in the rat.
The anti-bacterial action of diclofenac shown by inhibition of DNA synthesis.
Diclofenac metabolic profile following in vitro percutaneous absorption through viable human skin.
Non-steroidal anti-inflammatory drugs inhibit Helicobacter pylori-induced human neutrophil reactive oxygen metabolite production in vitro.
The progestin levonorgestrel induces endothelium-independent relaxation of rabbit jugular vein via inhibition of calcium entry and protein kinase C: role of cyclic AMP.
Prolonged hypercapnia-evoked cerebral hyperemia via K(+) channel- and prostaglandin E(2)-dependent endothelial nitric oxide synthase induction.
Adherence of neutrophils to human vascular cells cultured on microcarriers in a flow-through system: an alternative to animal experimentation
Irritation of gastrointestinal mucosa by new glycosyl derivative of diclofenac in comparison with diclofenac in rats.
Influence of electrical and chemical factors on transdermal iontophoretic delivery of three diclofenac salts.
Corneal complications associated with topical ophthalmic use of nonsteroidal antiinflammatory drugs.
Effects of vascular endothelial growth factor (VEGF)/vascular permeability factor (VPF) on haemodynamics and permselectivity of the isolated perfused rat kidney.
Identification of residues 286 and 289 as critical for conferring substrate specificity of human CYP2C9 for diclofenac and ibuprofen.
Effects of an antiinflammatory drug (diclofenac) in primary chronic glomerulo-nephritis
Biodegradable microspheres of novel segmented poly(ether-ester-amide)s based on poly(epsilon-caprolactone) for the delivery of bioactive compounds.
Enzymatic degradation of cross-linked high amylose starch tablets and its effect on in vitro release of sodium diclofenac.
Evaluation of methoxsalen, tranylcypromine, and tryptamine as specific and selective CYP2A6 inhibitors in vitro.
Inhibition of tendon cell proliferation and matrix glycosaminoglycan synthesis by non-steroidal anti-inflammatory drugs in vitro.
The lack of awareness of the Israeli population regarding gastrointestinal complications from non-steroidal anti-inflammatory drugs
Comparison of the physicochemical properties of the N-(2-hydroxyethyl) pyrrolidine, diethylamine and sodium salt forms of diclofenac.
Generation of 8-epi-prostaglandin F(2alpha) in isolated rat kidney glomeruli by a radical-independent mechanism.
Synthesis and anti-inflammatory properties of benzoyl, halogenobenzoyl or cinnamoyl substituted 1-benzoxepanes and 2-methyl-1-benzoxolanes.
Identification and functional characterization of a new CYP2C9 variant (CYP2C9*5) expressed among African Americans.
Inhibition of the endothelium-dependent relaxation by 18beta-glycyrrhetinic acid in the guinea-pig aorta.
Non-steroidal anti-inflammatory agents, Part 20. Method for testing non-steroidal anti-inflammatories: the modified hen's egg chorioallantoic membrane test (HET-CAM test) compared to other procedures.
Effects of lysine clonixinate on platelet function. Comparison with other non-steroidal anti-inflammatory agents
An autoradiographic study of regional blood flow distribution in the rat kidney during ureteric obstruction--the role of vasoactive compounds.
An in vitro investigation into the effect of glycosaminoglycans on the skin partitioning and deposition of NSAIDs.
An audit of the use of antirheumatic drugs in a north Indian referral hospital.
Functional characterization of rat organic anion transporter 2 in LLC-PK1 cells.
Preparation and characterisation of a range of diclofenac salts.
Monitoring diclofenac sodium in single human erythrocytes introduced by electroporation using capillary zone electrophoresis with electrochemical detection.
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In vivo regulation of vasomotricity by nitric oxide and prostanoids during gestation.
PGE2 synthesis by corneal endothelial cells: effect of glucocorticoids and NSAIDs.
Nonsteroidal anti-inflammatory drug as tools for analysis of neutrophil functions.
Nonsteroid anti-inflammatory drugs inhibit both the activity and the inflammation-induced expression of acid-sensing ion channels in nociceptors.
Roles of long chain fatty acids and carnitine in mitochondrial membrane permeability transition.
Anti-inflammatory drugs. X. Hydrated pyrrolidinium 2-(2,6-dichlorophenyl)aminophenylacetate(HP.D.H2O).
Thermal behaviour of diclofenac sodium: decomposition and melting characteristics.
Identification of dual cyclooxygenase-eicosanoid oxidoreductase inhibitors: NSAIDs that inhibit PG-LX reductase/LTB(4) dehydrogenase.
Micromeritic and packing properties of diclofenac pellets and effects of some formulation variables.
Influence of anti-inflammatory drugs on adhesion of neutrophils to endothelial cells cultured on microcarriers: a novel in vitro system as an alternative to animal experimentation.
Sodium salicylate inhibits prostaglandin formation without affecting the induction of cyclooxygenase-2 by bacterial lipopolysaccharide in vivo.
Characterization of the selectivity and mechanism of cytochrome P450 inhibition by dimethyl-4,4'-dimethoxy-5,6,5',6'-dimethylenedioxybiphenyl-2,2'-dicarboxylate.
Indomethacin and ibuprofen enhance anoxia-induced hyperemia in rat brain.
Anti-inflammatory effect of synthetic somatostatin analogues in the rat.
Adverse drug reactions related to the use of NSAIDs with a focus on nimesulide: results of spontaneous reporting from a Northern Italian area.
Ligation-anopexy for treatment of advanced hemorrhoidal disease.
Compression forces and amount of outer coating layer affecting the time-controlled disintegration of the compression-coated tablets prepared by direct compression with micronized ethylcellulose.
Diclofenac antagonizes peroxisome proliferator-activated receptor-gamma signaling.
Synthesis and evaluation of a nonsteroidal anti-inflammatory polymeric prodrug for sustained and site-specific delivery.
Inhibition of coumarin 7-hydroxylase activity in human liver microsomes.
Treatment of non-malignant pain in the Dutch GP population: an analysis of treatment standards, prescription habits and basic attitudes.
Over-the-counter oral nonsteroidal anti-inflammatory drugs: a pharmacoepidemiologic study in southern Italy.
Comparison of cardiovascular thrombotic events in patients with osteoarthritis treated with rofecoxib versus nonselective nonsteroidal anti-inflammatory drugs (ibuprofen, diclofenac, and nabumetone).
The effect of bronchial epithelium on bronchial contractility
Corneal melts associated with topically applied nonsteroidal anti-inflammatory drugs.
Cyclooxygenase-1 and cyclooxygenase-2 selectivity of non-steroidal anti-inflammatory drugs: investigation using human peripheral monocytes.
Use of nonsteroidal anti-inflammatory drugs and gastroprotective agents before the advent of cyclooxygenase-2-selective inhibitors: analysis of a large United States claims database.
Quantitation in gradient high performance liquid chromatography/inductively coupled mass spectrometry investigated using diclofenac and chlorpromazine.
Grapefruit juice potentiates the anti-inflammatory effects of diclofenac on the carrageenan-induced rat's paw oedema.
Contribution of cytochrome P450 metabolites to bradykinin-induced vasodilation in endothelial NO synthase deficient mouse hearts.
Effect of Food on the Multiple-Peak Behavior After a Single Oral Dose of Diclofenac Sodium Slow-Release Tablet in Humans.
Inhibition of human hepatic cytochrome P450s and steroidogenic CYP17 by nonylphenol.
Effect of Misoprostol on Acute and Chronic Inflammation.
Nonsteroidal Anti-Inflammatory Drugs and Prostaglandins: Their Interactions and Effects on the Particulate-Induced Inflammatory Process Implicated in Joint Implant-Loosening and on Monosodium Urate Crystal-Induced Inflammation.
Antirheumatic drug profiles evaluated in the adjuvant arthritis of rats by multiparameter analysis.
The Analgesic Interaction of Misoprostol with Nonsteroidal Anti-Inflammatory Drugs.
Placentally derived prostaglandin E2 acts via the EP4 receptor to inhibit IL-2-dependent proliferation of CTLL-2 T cells.
Differential binding mode of diverse cyclooxygenase inhibitors.
BALB/c mice orally pretreated with diclofenac have augmented and accelerated PLNA responses to diclofenac.
Nonsteroidal antiinflammatory drugs: effects on normal and interleukin 1 treated human articular chondrocyte metabolism in vitro.
Antioxidant and anti-inflammatory activities of methanol extract of Phellinus rimosus (Berk) Pilat.
Treatment of traumatic corneal abrasion with contact lens associated with topical nonsteroid anti-inflammatory agent (NSAID) and antibiotic: a safe, effective and comfortable solution
Nucleus pulposus-induced nerve root injury: effects of diclofenac and ketoprofen.
Effects of flavonoids isolated from Scutellariae radix on cytochrome P-450 activities in human liver microsomes.
H(+)-linked transport of salicylic acid, an NSAID, in the human trophoblast cell line BeWo.
Effect of polyol fatty acid esters on diclofenac permeation through rat skin.
Lengthening contraction-induced inflammation is linked to secondary damage but devoid of neutrophil invasion.
PGE(2)-mediated eNOS induction in prolonged hypercapnia.
Comparison between capillary electrophoresis and liquid chromatography for the determination of diclofenac sodium in a pharmaceutical tablet.
Determination of diclofenac in rat bile and its interaction with cyclosporin A using on-line microdialysis coupled to liquid chromatography.
Ocular drug permeation following experimental excimer laser treatment on the isolated pig eye.
Inhibition of vascular smooth muscle cell migration by cytochrome p450 epoxygenase-derived eicosanoids.
Mechanisms underlying the contraction induced by bradykinin in the guinea pig epithelium-denuded trachea.
Pain relief in induced abortion--considerable differences between hospital departments
Synthesis and evaluation of rosin-based polymers as film coating materials.
Analysis of acidic drugs in the effluents of sewage treatment plants using liquid chromatography-electrospray ionization tandem mass spectrometry.
Relationship between etiological factors and total motile sperm count in 350 infertile patients.
Nonsteroidal anti-inflammatory drugs induce apoptosis in association with activation of peroxisome proliferator-activated receptor gamma in rheumatoid synovial cells.
Effect of inflammatory mediators on the physiology of the human Fallopian tube.
Evaluation of intestinal absorption into the portal system in enterohepatic circulation by measuring the difference in portal-venous blood concentrations of diclofenac.
The effect of nonsteroidal antiinflammatory drugs ibuprofen, flurbiprofen, and diclofenac on in vitro and in vivo growth of mouse fibrosarcoma.
Effect of some anti-inflammatory drugs on human neutrophil chemotaxis.
Synthesis, antiinflammatory and analgesic activity of new hexahydropyrimidine derivatives.
Amino acid residues affecting the activities of human cytochrome P450 2C9 and 2C19.
Mechanism of the prorelaxing effect of thyroxine on the sphincter of Oddi.
Structure-function relationship and role of tumor necrosis factor-alpha-converting enzyme in the down-regulation of L-selectin by non-steroidal anti-inflammatory drugs.
Inhibition of lotic biofilms by Diclofenac.
Quantitative criteria for evaluating the early development of osteoarthritis and the effect of diclofenac sodium.
Drugs and personal care products as ubiquitous pollutants: occurrence and distribution of clofibric acid, caffeine and DEET in the North Sea.
NMR study on the low-affinity interaction of human serum albumin with diclofenac sodium.
Design, development, physicochemical, and in vitro and in vivo evaluation of transdermal patches containing diclofenac diethylammonium salt.
A new method of continuous maxillary nerve block with an indwelling catheter.
Diclofenac-induced inactivation of CYP3A4 and its stimulation by quinidine.
Accelerated mineralization of the drug Diclofenac via Fenton reactions in a concentric photo-reactor.
Decrease in efficacy and potency of nonsteroidal anti-inflammatory drugs by chronic delta(9)-tetrahydrocannabinol administration.
Intercalation and controlled release of pharmaceutically active compounds from a layered double hydroxide.
A pharmacoeconomic comparison of misoprostol/diclofenac with diclofenac.
Rat retinal tissue releases a vasorelaxing factor.
Retroperitoneoscopic excision of phaeochromocytoma--haemodynamic events, complications and outcome.
Modulation of cell recruitment by anti-inflammatory agents in antigen-induced arthritis.
Endothelin-induced vascular and bronchial effects in pig airways: role in acute allergic responses.
Synergistic effects of nitric oxide and prostaglandins on renal escape from vasopressin-induced antidiuresis.
Infectious factors in acute acalculous cholecystitis.
Effect of various vehicles on diclofenac sodium and indomethacin pharmaceutical availability.
Comparison of the baseline cardiovascular risk profile among hypertensive patients prescribed COX-2-specific inhibitors or nonspecific NSAIDs: data from real-life practice.
Cost of heart failure among hypertensive users of nonspecific NSAIDs and COX-2-specific inhibitors.
Availability of TPD ophthalmic solution (mixture of Mydrin-P solution, Neosynesin Kowa solution, and Diclod solution) in regard to the corneal barrier function--clinical evaluation for vitrectomy in patients with diabetic retinopathy
Comparison of the anti-inflammatory effect and gastrointestinal tolerability of aceclofenac and diclofenac.
Modulation of IL-1beta, IL-6, TNF-alpha and PGE(2) by pharmacological agents in explants of membranes from failed total hip replacement.
Topical treatment of experimental acute corneal inflammation by dexamethasone and nonsteroidal drugs.
Glycation of human serum albumin: inhibition by Diclofenac.
Residues glutamate 216 and aspartate 301 are key determinants of substrate specificity and product regioselectivity in cytochrome P450 2D6.
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Role of conserved Asp293 of cytochrome P450 2C9 in substrate recognition and catalytic activity.
Cyclooxygenase inhibitor blocks rebound response after NO inhalation in an endotoxin model.
Effect of metamizol on promyelocytic and terminally differentiated granulocytic cells. Comparative analysis with acetylsalicylic acid and diclofenac.
Albumin binding of anti-inflammatory drugs. Utility of a site-oriented versus a stoichiometric analysis.
Cationic cellulose hydrogels: kinetics of the cross-linking process and characterization as pH-/ion-sensitive drug delivery systems.
Effects of diclofenac sodium combined with dionine in cases with fibrinous membrane after intraocular lens implantation
Use of nonsteroidal anti-inflammatory drugs and risk of fractures.
Role of volatile oil pretreatment and skin cholesterol on permeation of ion-paired diclofenac sodium.
Study of the solid-phase extraction of diclofenac sodium, indomethacin and phenylbutazone for their analysis in human urine by liquid chromatography.
Oral controlled release formulation of diclofenac sodium by microencapsulation with ethyl cellulose.
Alpha2-adrenoceptor ligands inhibit alpha1-adrenoceptor-mediated contraction of isolated rat arteries.
Synthesis and anti-inflammatory analgesic activities of phenylfuroxan-coupled diclofenac
Determination of polar pharmaceuticals in sewage water of Greece by gas chromatography-mass spectrometry.
Effect of zinc on the anti-inflammatory and ulcerogenic activities of indometacin and diclofenac.
Fluvastatin prevents renal dysfunction and vascular NO deficit in apolipoprotein E-deficient mice.
Binding of nonsteroidal antiinflammatory drugs to the alpha-subunit of the trifunctional protein of long chain fatty acid oxidation.
Effects of non-steroidal anti-inflammatory drugs on the methotrexate transport in rat small intestine.
Antithrombotic and antinflammatory drugs for protection of microvascular anastomosis.
The influence of drug type on the release profiles from Surelease-coated pellets.
Diclofenac sodium versus fentanyl for analgesia in laparoscopic sterilization.
Anti-inflammatory drugs: 1-(2-hydroxyethyl)pyrrolidinium salt of diclofenac.
Physicochemical characterization and in vivo evaluation of thermosensitive diclofenac liquid suppository.
Anti-inflammatory and antinociceptive effects in rodents of the essential oil of Croton cajucara Benth.
Search of antimicrobial activity of selected non-antibiotic drugs.
In vitro study of the antioxidant properties of non steroidal anti-inflammatory drugs by chemiluminescence and electron spin resonance (ESR).
Neosynephrine mydriasis combined with general anesthesia with halothane in ocular surgery
Mechanisms of hydrogen-peroxide-induced biphasic response in rat mesenteric artery.
Effects of some probable antioxidants on selenite-induced cataract formation and oxidative stress-related parameters in rats.
Effect of quercetin on sodium diclofenac-induced ulceration
An inhibitory monoclonal antibody to human cytochrome P450 that specifically binds and inhibits P4502C9II, an allelic variant of P4502C9 having a single amino acid change Arg144 Cys.
Exercise improves flow-mediated vasodilatation of skeletal muscle arteries in rats with chronic heart failure. Role of nitric oxide, prostanoids, and oxidant stress.
Influence of nonsteroidal anti-inflammatory drug treatment duration and time of onset on recovery from exercise-induced muscle damage in rats.
Analysis of diclofenac and its metabolites by high-performance liquid chromatography: relevance of CYP2C9 genotypes in diclofenac urinary metabolic ratios.
Interaction of buprenorphine and its metabolite norbuprenorphine with cytochromes p450 in vitro.
No major difference in inhibitory susceptibility between CYP2C9.1 and CYP2C9.3.
Evidence for the participation of arachidonic acid metabolites in trehalose efflux from the hormone activated fat body of the cockroach (Periplaneta americana).
Preventive effect of zaprinast and 3-isobutyl, 1-methylxanthine (phosphodiesterase inhibitors) on gastric injury induced by nonsteroidal antiinflammatory drugs in rats.
Physicochemical characterization of diclofenac sodium-loaded poloxamer gel as a rectal delivery system with fast absorption.
Characterisation of some cytotoxic endpoints using rat liver and HepG2 spheroids as in vitro models and their application in hepatotoxicity studies. I. Glucose metabolism and enzyme release as cytotoxic markers.
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Ecotoxicological impact of pharmaceuticals found in treated wastewaters: study of carbamazepine, clofibric acid, and diclofenac.
Application of Folin-Ciocalteu reagent for the spectrophotometric determination of some nonsteroidal antiinflammatory agents.
Management of postoperative pain in children
Estimation of absorption parameters from the non-steady-state phase in the rat gut perfusion model.
Design and feasibility assessment of topically applied drug formulations for electroporation.
Effects of non-steroidal anti-inflammatory drugs on human leucocytes.
Voltammetric response of diclofenac-molecularly imprinted film modified carbon electrodes.
On the mechanisms underlying histamine induction of gastric mucosal lesions in rats with partial gastric vascular occlusion.
Inhibition of immunoglobulin G-catalyzed hydrogen peroxide generation by dexamethasone and piroxicam.
Nonsteroidal anti-inflammatory drug reduces neutrophil and macrophage accumulation but does not improve tendon regeneration.
Effects of nonsteroidal anti-inflammatory drugs on interleukin-1 receptor antagonist production in cultured human peripheral blood mononuclear cells.
RGD-anchored magnetic liposomes for monocytes/neutrophils-mediated brain targeting.
The treatment of pain following excimer laser photorefractive keratectomy: additive effect of local anesthetic drops, topical diclofenac, and bandage soft contact.
Antithrombin III level in patients with acute viral myocarditis
The effects of pentoxifylline on renal function and free radical production in unilateral ureteral obstruction.
Capillary electrophoresis to assess drug metabolism induced in vitro using single CYP450 enzymes (Supersomes): application to the chiral metabolism of mephenytoin and methadone.
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Intercalation compounds of hydrotalcite-like anionic clays with anti-inflammatory agents, II: Uptake of diclofenac for a controlled release formulation.
Aged spontaneously hypertensive rats exhibit a selective loss of EDHF-mediated relaxation in the renal artery.
Preparation and in vitro evaluation of chitosan matrices for colonic controlled drug delivery.
In vitro evaluation of antiproliferative potential of topical cyclooxygenase inhibitors in human Tenon's fibroblasts.
Efficiency of Potentiated Antibodies to Tumor Necrosis Factor-alpha (Artrofoon) in the Therapy of Patients with Rheumatoid Arthritis.
Improving the effectiveness of the emergency management of renal colic in a district general hospital: a completed audit cycle.
Submicron emulsion vehicle for enhanced transdermal delivery of steroidal and nonsteroidal antiinflammatory drugs.
Fish Balistes capriscus skin extract-induced relaxation in mesenteric arterial bed of rat.
Differential expression and function of CYP2C isoforms in human intestine and liver.
Naclof and dexamethasone in topical application after trabeculectomy
The NO-cGMP-K(+) channel pathway participates in the antinociceptive effect of diclofenac, but not of indomethacin.
NADPH oxidase and enhanced superoxide generation in intrauterine undernourished rats: involvement of the renin-angiotensin system.
Formation of an artifact of diclofenac during acidic extraction of environmental water samples.
Stapled hemorrhoidectomy for the treatment of hemorrhoids.
Liquid chromatography with triple-quadrupole or quadrupole-time of flight mass spectrometry for screening and confirmation of residues of pharmaceuticals in water.
Mechanism-based inhibition of human liver microsomal cytochrome P450 1A2 by zileuton, a 5-lipoxygenase inhibitor.
Human cytochrome p450 inhibition and metabolic-intermediate complex formation by goldenseal extract and its methylenedioxyphenyl components.
Effects of a new foam formulation of ketoprofen lysine salt in experimental models of inflammation and hyperalgesia.
Drugs for nocturnal enuresis in children (other than desmopressin and tricyclics).
Characterization of binary mixtures consisting of cross-linked high amylose starch and hydroxypropylmethylcellulose used in the preparation of controlled release tablets.
Freeze-drying polymeric colloidal suspensions: nanocapsules, nanospheres and nanodispersion. A comparative study.
Treatment of secondary hyperparathyroidism by high calcium diet is associated with enhanced resistance artery relaxation in experimental renal failure.
Ulcerogenic and antiulcerogenic effects of a new antiinflammatory drug, the gamma-lactone-N-ethyl derivative of 6-1S-(3S,4-dihydro-8-hydroxy-1H-2-benzo- pyran-1-one-3-yl)-3-methylbutylamino-4S,5S-dihydroxy-6-oxo-3S- ammoniohexanoate, on gastrointestinal tract in rats.
In Process Citation
Effect of microenvironment pH of swellable and erodable buffered matrices on the release characteristics of diclofenac sodium.
Randomised controlled trial of the onset of analgesic efficacy of dexketoprofen and diclofenac in lower limb injury.
Developmental Expression of Human Hepatic CYP2C9 and CYP2C19.
Effect of mixed micelle formulations including terpenes on the transdermal delivery of diclofenac.
New mathematical approach for the evaluation of drug binding to human serum albumin by high-performance liquid affinity chromatography.
B-vitamins potentiate the antinociceptive effect of diclofenac in carrageenin-induced hyperalgesia in the rat tail pressure test.
Relative contribution of estrogen withdrawal and gonadotropins increase secondary to ovariectomy on prostaglandin generation in mesenteric microvessels.
On the efficiency of new antiinflammatory agents. A comparative study
Celecoxib has a positive effect on the overall metabolism of hyaluronan and proteoglycans in human osteoarthritic cartilage.
PLA2/PGE2 are involved in the inhibitory effect of bradykinin on the angiotensin-(1-7)-stimulated Na(+)-ATPase activity of the proximal tubule.
Comparison of different anti-inflammatory agents in suppressing the monocyte response to orthopedic particles.
Inhibition of acid secretion by the nonsteroidal antiinflammatory drugs diclofenac and piroxicam in isolated gastric glands: Analysis of a multifocal mechanism.
A prospective, randomised trial of preoperative rectal diclofenac: are we closing the gate after the horse has gone?
The efficacy and cost effectiveness of N of 1 studies with diclofenac compared to standard treatment with nonsteroidal antiinflammatory drugs in osteoarthritis.
Cystitis and nonsteroidal antiinflammatory drugs: an incidental association or an adverse effect?
The role of tumour necrosis factor-alpha (TNF-alpha) in fever and the acute phase reaction in rabbits.
Enalapril interferes with the effect of diclofenac on leucocyte-endothelium interaction in hypertensive rats.
Intermittent infusion of 0.25% bupivacaine through an intrapleural catheter for post-thoracotomy pain relief.
The inhibitory effects of antirheumatic drugs on the activity of human leukocyte elastase and cathepsin G.
Synthesis and anti-inflammatory activity of alpha-substituted p-(methanesulfonyl)phenylpropenamides
Synthesis and comparative anti-phlogistic potency of new proteinogenic amino acid conjugates of 2-2,6-dichlorophenyl-1-aminophenyl acetic acid "diclofenac".
A comparison of gastrointestinal permeability induced by diclofenac-phospholipid complex with diclofenac acid and its sodium salt.
Influence of adrenomedullin on tone of isolated bovine retinal arteries.
Influence of nonsteroidal anti-inflammatory drugs on calcium efflux in isolated rat renal cortex mitochondria and aspects of the mechanisms involved.
Methanol extract of the oyster mushroom, Pleurotus florida, inhibits inflammation and platelet aggregation.
Efficacy of Diclofenac Sodium Softgel 100 mg With or Without Caffeine 100 mg in Migraine Without Aura: A Randomized, Double-blind, Crossover Study.
Stimulated elastase release from human leukocytes: influence of anti-asthmatic, anti-inflammatory and calcium antagonist drugs in vitro.
Analgesic action of sodium diclofenac: behavioral and electrophysiological study in normal and polyarthritic rats
A 22-year experience with quinacrine sterilization in a rural private clinic in Midnapore, India: a report on 5 protocols and 1838 cases.
Management of third degree perineal tear and choice of mode of delivery in subsequent pregnancies.
Native state stabilization by NSAIDs inhibits transthyretin amyloidogenesis from the most common familial disease variants.
Paracetamol versus nonsteroidal anti-inflammatory drugs for rheumatoid arthritis.
Diclofenac, paracetamol, and vidarabine removal during plasma exchange in polyarteritis nodosa patients.
Effects of unilateral cortex lesions on gene expression of rat cortical cholecystokinin neurons.
The relative bioavailability of diclofenac with respect to time of administration.
Comparison of the effects of non-steroidal anti-inflammatory drugs (NSAIDs) on proteoglycan synthesis by articular cartilage explant and chondrocyte monolayer cultures.
Photochemical studies on the anti-inflammatory drug diclofenac.
Aging phenomena of chitosan and chitosan-diclofenac sodium system detected by low-frequency dielectric spectroscopy.
The infrequency of liver function testing in patients using nonsteroidal anti-inflammatory drugs.
Effects of anti-inflammatory agents on mucosal inflammation induced by infection with gram-negative bacteria.
Pharmacological influence on polymorphonuclear granulocytes elastase under various test conditions.
The non-aqueous titrimetric assay of the selected anti-inflammatory agents using tetra-n-butylammonium hydroxide as titrant.
Effect of anti-inflammatory agents on corneal wound-healing process after surface excimer laser keratectomy.
Effects of diclofenac sodium and disodium ethylenediaminetetraacetate on electrical parameters of the mucosal membrane and their relation to the permeability enhancing effects in the rat jejunum.
The influence in the rat of counter-irritation by turpentine on the leukocyte content of exudates induced by sponge implants
The effects of modulation of prostanoid metabolism on the thoracic platelet accumulation induced by intravenous administration of collagen in the guinea-pig.
Effect of diclofenac sodium (Voltaren) on spermatogenesis of infertile oligospermic patients.
Comparison of the inhibitory effect of nonsteroidal antiinflammatory drugs on bone prostaglandin synthesis and resorption.
A comparison of indomethacin and diclofenac in the inhibition of experimental heterotopic new bone formation.
Preservation of neural function in the perinate by high PGE(2) levels acting via EP(2) receptors.
The percutaneous absorption of diclofenac
From Beaumont to poison ivy: marine sponge cell aggregation and the secretory basis of inflammation.
AD-1590, a potent antagonist of lipopolysaccharide-induced fever in rabbits.
Localization of the central antinociceptive effects of diclofenac in the rat.
Effect of diclofenac sodium (feloran) on platelet aggregation.
Effect of some prostaglandin synthesis inhibitors on the antinociceptive action of morphine in albino rats.
The influence of food on the absorption of diclofenac after single and multiple oral doses.
Topical diclofenac following excimer laser: effect on corneal sensitivity and wound healing in rabbits.
Effects of tenidap on canine experimental osteoarthritis. I. Morphologic and metalloprotease analysis.
Antiaggregative therapy with acetylsalicylic acid and diclofenac in patients with acute myocardial infarction.
Acute antiinflammatory and gastric effects of the seleno-organic compound ebselen.
The pharmacokinetics of the new Russian prolonged-action form of diclofenac sodium--Ortopek--in a single oral dose
Modified screening procedure with fluorescence detection for flunitrazepam and its metabolites via acridine derivatives.
Topical diclofenac treatment prior to excimer laser photorefractive keratectomy in rabbits.
Determination of diclofenac and its metabolites in plasma and cerebrospinal fluid by high-performance liquid chromatography with electrochemical detection.
Converting enzyme inhibition modulates sympathetic neurotransmission in vivo via multiple mechanisms.
Cytochrome P450TB (CYP2C): a major monooxygenase catalyzing diclofenac 4'-hydroxylation in human liver.
Covalent modification of rat liver dipeptidyl peptidase IV (CD26) by the nonsteroidal anti-inflammatory drug diclofenac.
Human whole blood assays for inhibition of prostaglandin G/H synthases-1 and -2 using A23187 and lipopolysaccharide stimulation of thromboxane B2 production.
Tenidap reduces the level of interleukin 1 receptors and collagenase expression in human arthritic synovial fibroblasts.
Modelling of indometacin and diclofenac sodium binding to the molecule of human serum albumin.
Effect of histamine on gastric acid secretion "in vitro": interference with endogenous prostaglandins.
Diclofenac sodium attenuates neural activity after photorefractive keratectomy in rabbits.
Signal transduction pathways in modulation of ciliary beat frequency by methacholine.
Evaluation of the effect of antiarthritic drugs on the secretion of proteoglycans by lapine chondrocytes using a novel assay procedure.
Deranged hydrophobic barrier of the rat gastroduodenal mucosa after parenteral nonsteroidal anti-inflammatory drugs.
Effects of the combined oral administration of NSAIDs and dextromethorphan on behavioral symptoms indicative of arthritic pain in rats.
Study on paradoxical effects of NSAIDs on platelet activation.
Water-soluble polycations as oral drug carriers (tablets).
Anti-inflammatory properties of new adamantane derivatives. Design, synthesis, and biological evaluation.
The effect of endothelin on granulocyte-endothelium interaction
Anti-inflammatory properties of diclofenac transition metalloelement complexes.
Economic and gastrointestinal safety comparisons of etodolac, nabumetone, and oxaprozin from insurance claims data from patients with arthritis.
Interference of nonsteroidal antiinflammatory drugs with very late activation antigen 4/vascular cells adhesion molecule 1-mediated lymphocyte-endothelial cell adhesion.
Diclofenac acyl glucuronide, a major biliary metabolite, is directly involved in small intestinal injury in rats.
Comparison of the effects of supplementation with whey mineral and potassium on arterial tone in experimental hypertension.
Treatment of experimental poly-D-lysine arthritis in rabbits by non-steroidal anti-inflammatory compounds.
Characterization of polyvinylalcohol microspheres of diclofenac sodium: application of statistical design.
Drug induced impairment of polymorphonuclear cell bactericidal ability in rheumatoid arthritis.
Drug enterocyte adducts: possible causal factor for diclofenac enteropathy in rats.
Effects of calcium and potassium supplements on arterial tone in vitro in spontaneously hypertensive rats.
Age-related changes in skin permeability of hydrophilic and lipophilic compounds in rats.
A major role for cytochrome P450TB (CYP2C subfamily) in the actions of non-steroidal antiinflammatory drugs.
Peptic ulcer and gastrointestinal hemorrhage associated with nonsteroidal anti-inflammatory drug use in patients younger than 65 years. A large health maintenance organization cohort study.
Effect of kininotropic preparations on ulcer formation in rats
Chronic dexamethasone pretreatment aggravates ischemic neuronal necrosis.
Morpholinoalkyl ester prodrugs of diclofenac: synthesis, in vitro and in vivo evaluation.
Chemical properties-dissolution relationship. IV. Behaviour in solution of the diclofenac/N-(2-hydroxyethyl) pyrrolidine salt (DHEP).
Inhibitory effects of propofol on acetylcholine-induced, endothelium-dependent relaxation and prostacyclin synthesis in rabbit mesenteric resistance arteries.
Role of prostaglandin-mediated cyclic AMP formation in protein kinase C-dependent secretion of atrial natriuretic peptide in rat cardiomyocytes.
Arginine 120 of prostaglandin G/H synthase-1 is required for the inhibition by nonsteroidal anti-inflammatory drugs containing a carboxylic acid moiety.
Possible role of prostaglandins in pathogenesis of nocturnal enuresis in children.
The influence of prostaglandins, cyclooxygenase and lipoxygenase inhibitors on collagen concentration in the rat uterine cervix.
The action of non-steroidal antiinflammatory agents on platelet aggregation and vessel tone in relation to inhibition of PGI2- and thromboxane-release. With particular reference to 5-benzoyl-alpha-methyl-2-thiophene acetic acid (tiaprofenic acid).
The influence of age, gender, Helicobacter pylori and smoking on gastric mucosal adaptation to non-steroidal anti-inflammatory drugs.
The possible role of prostaglandin D2 in the long-lasting airways vasodilatation induced by allergen in the sensitized pig.
In vivo inhibition of prostaglandin synthesis in rabbit kidney by non-steroidal anti-inflammatory drugs.
Effect of etodolac on prostaglandin E2 biosynthesis, active oxygen generation and bradykinin formation.
ML 3000 reduces gastric prostaglandin synthesis without causing mucosal injury.
Aspirin and salicylate protect against MPTP-induced dopamine depletion in mice.
Stimulation of collagenase production in human synovial fibroblast cultures by poly (I). poly (C).
Lactic acid-induced plasma protein extravasation in rat airways by stimulation of sensory nerves and NK1 receptor activation.
Filtration surgery in rabbits treated with diclofenac or prednisolone acetate.
Application of dual radiotelemetric technique in studying drug-drug interaction between diclofenac sodium and ranitidine HCl in volunteers.
Drug associated hepatic reactions in New Zealand: 21 years experience.
Membranous glomerulonephritis during rheumatoid arthritis. Probable toxicity of diclofenac
Patients' attitudes to rectal drug administration.
Angiostasis and vascular regression in chronic granulomatous inflammation induced by diclofenac in combination with hyaluronan in mice.
Prostacyclin stimulates relaxin release from cultured porcine luteal cells.
Comparative study of drug release from pellets coated with HPMC or Surelease.
Use of topical nonsteroidal anti-inflammatory drugs in excimer laser photorefractive keratectomy.
Regional drug delivery II: relationship between drug targeting index and pharmacokinetic parameters for three non-steroidal anti-inflammatory drugs using the rat air pouch model of inflammation.
A review of spontaneously reported adverse drug reactions with diclofenac sodium (Voltarol).
Determination of drug residues in water by the combination of liquid chromatography or capillary electrophoresis with electrospray mass spectrometry.
Variations of arterial responses in vitro in different sections of rat main superior mesenteric artery.
Experiences with the 14C-aminopyrine breath test in liver cirrhosis and under the effect of sodium diclofenac (Voltaren)
Management of NSAID-induced gastropathy: an economic decision analysis.
NSAID-induced apoptosis in Rous sarcoma virus-transformed chicken embryo fibroblasts is dependent on v-src and c-myc and is inhibited by bcl-2.
Evans blue extravasation in rat dental pulp and oral tissues induced by electrical stimulation of the inferior alveolar nerve.
Cardiovascular effects of Sar-D-Phe8des-Arg9-bradykinin, a metabolically protected agonist of B1 receptor for kinins, in the anesthetized rabbit pretreated with a sublethal dose of bacterial lipopolysaccharide.
Uveal inflammation secondary to lens implantation
Means of increasing sensitivity of an in vitro diagnostic test for aspirin intolerance.
Simultaneous analysis of several non-steroidal anti-inflammatory drugs in human urine by high-performance liquid chromatography with normal solid-phase extraction.
Lack of effect of a single-dose of sulglicotide on the bioavailability of diclofenac.
Enhancement of slow-wave sleep by tumor necrosis factor-alpha is mediated by cyclooxygenase-2 in rats.
The effect of diclofenac sodium on urinary concentration of calcium, uric acid and glycosaminoglycans in traumatic paraplegics.
Renal prostaglandins and sodium balance in the rabbit: lack of effect of aspirin-like drugs.
Effects of diacerhein on granuloma induced cartilage breakdown in the mouse.
In vitro protein binding of diclofenac sodium in plasma and synovial fluid.
Transfer of diclofenac sodium across excised guinea pig skin on high-frequency pulse iontophoresis. I. Equivalent circuit model.
Stability of diclofenac sodium in the inclusion complex with beta-cyclodextrin in the solid state.
The effects of diclofenac sodium on arachidonic acid metabolism.
Pharmacology of diclofenac sodium.
Europium(III) ion probe spectrofluorometric determination of diclofenac sodium.
Flow extraction spectrophotometric method for the determination of diclofenac sodium in pharmaceutical preparations.
Hemorrhagic colon ulcer as a side effect of non-steroidal anti-inflammatory drugs in five aged patients
Decrease of inorganic blood sulfate following treatment with selected antirheumatic drugs: potential consequence for articular cartilage.
The chemistry of diclofenac sodium (Voltarol).
Effect of piroxicam on the structure and function of joint cartilage
Effects of stroma-free hemoglobin solutions on pulmonary vascular resistance and mediator release in the isolated perfused rabbit lung.
Determination of diclofenac sodium, famotidine and ketorolac tromethamine by flow injection analysis using dichloronitrophenol.
The role of endothelin-1 as a mediator of the pressure response after air embolism in blood perfused lungs.
Synthesis and quantitative structure-activity relationships of diclofenac analogues.
Corneal wound healing strength with topical antiinflammatory drugs.
In vitro and in vivo studies of diclofenac suppositories in humans
Experimental comparative study of the anti-inflammatory effectiveness of pranoprofen
Inhibition of vasoactive substances in experimental endotoxin shock.
4'-Hydroxy aceclofenac suppresses the interleukin-1-induced production of promatrix metalloproteinases and release of sulfated-glycosaminoglycans from rabbit articular chondrocytes.
Aging enhances susceptibility of diclofenac-treated rats to gastric ulceration, while attenuating enteropathy.
Role of prostaglandin synthesis inhibitors in the passage of ureteric calculus.
Immunopharmacological analysis of endotoxin-induced uveitis in the rat.
Aspirin increases ferritin synthesis in endothelial cells: a novel antioxidant pathway.
Blood-vessel wall arachidonate metabolism and its pharmacological modification in a new in vitro assay system.
The influence of carbon tetrachloride-induced liver damage on the inflammatory reaction elicited by carrageenan and its treatment with diclofenac.
Vasoactive eicosanoids in the rat heart: clues to a contributory role of cardiac thromboxane to post-ischaemic hyperaemia.
Ultrastructural study of the liver in rabbits treated with diclofenac
Antibacterial activity of the antiinflammatory agent diclofenac sodium.
Combined non-steroidal therapy in experimental corneal injury.
Simplified micromethod for the HPLC measurement of diclofenac in plasma.
Ebselen: a new approach to the inhibition of peroxide-dependent inflammation.
Lowering of the convulsive threshold by non-steroidal anti-inflammatory drugs.
Diclofenac toxicity to hepatocytes: a role for drug metabolism in cell toxicity.
Application of higher throughput screening (HTS) inhibition assays to evaluate the interaction of antiparasitic drugs with cytochrome P450s.
Press-coated tablets for time-programmed release of drugs.
CYP2C19 participates in tolbutamide hydroxylation by human liver microsomes.
Objective assessment of topical corticosteroids and non-steroidal anti-inflammatory drugs in methyl-nicotinate-induced skin inflammation.
Improvement of the gastric tolerance of non-steroidal anti-inflammatory drugs by polyene phosphatidylcholine (Phospholipon 100).
The effect of diclofenac on the expression of spinal cord c-fos-like immunoreactivity after ischemia-reperfusion-induced acute hyperalgesia in the rat tail.
Mutagenicity of analgesics, their derivatives, and anti-inflammatory drugs with S-9 mix of several animal species.
Markedly reduced intestinal toxicity of a diclofenac derivative.
The effect of hyaluronan on the in vitro deposition of diclofenac within the skin.
The effect of diclofenac acid (Voltaren) on bleomycin-induced pulmonary fibrosis in hamsters.
Possible role of HLA in hepatotoxicity. An exploratory study in 71 patients with drug-induced idiosyncratic hepatitis.
Combination therapy of transcutaneous electric nerve stimulation and iontophoresis with benzydamine and diclofenac
Proglumetacin for the treatment of inflammatory and degenerative arthropathies
Ramipril therapy improves arterial dilation in experimental hypertension.
Intestinal UDP-glucuronosyltransferase activities in rat and rabbit.
Predicting NSAID related ulcers--assessment of clinical and pathological risk factors and importance of differences in NSAID.
Effects of selective and unselective cyclooxygenase inhibitors on prostanoid release from various rat organs.
Vasodilator effect of urotensin II, one of the most potent vasoconstricting factors, on rat coronary arteries.
Thoracoscopic surgery by use of endo-GIA
High-calcium diet enhances vasorelaxation in nitric oxide-deficient hypertension.
Acetylcholine-induced vasoconstrictor response of coronary vessels in rats: a possible contribution of M2 muscarinic receptor activation.
Extractionless high-performance liquid chromatographic method for the determination of diclofenac in human plasma and urine.
Preferential venoconstriction by cyclooxygenase inhibition in vivo without attenuation of nitroglycerin venodilation.
Diclofenac sodium (Voltarol): drug interactions and special studies.
Small bowel permeability--a variable effect of NSAIDS.
Water distribution studies within cellulose ethers using differential scanning calorimetry. 1. Effect of polymer molecular weight and drug addition.
Results of efficacy study with diclofenac/orphenadrine infusions in patients with musculoskeletal diseases and functional disorders
Phototoxicity associated with diclofenac: a photophysical, photochemical, and photobiological study on the drug and its photoproducts.
Characterization of augmentation of allergic and non-allergic histamine release by non-steroidal anti-inflammatory/analgesic agents.
Determination of drug availability from commercial topical formulations with a multilayer membrane model
Formulation and release behavior of diclofenac sodium in Compritol 888 matrix beads encapsulated in alginate.
Transforming growth factor beta 2 differentially modulates interleukin-1 beta- and tumour-necrosis-factor-alpha-stimulated phospholipase A2 and prostaglandin E2 synthesis in rat renal mesangial cells.
Clinical, endoscopic, and histologic spectrum of nonsteroidal anti-inflammatory drug-induced lesions in the colon.
A transferable, beta-naphthoflavone-inducible, hyperpolarizing factor is synthesized by native and cultured porcine coronary endothelial cells.
Biosynthesis of 18(RD)-hydroxyeicosatetraenoic acid from arachidonic acid by microsomes of monkey seminal vesicles. Some properties of a novel fatty acid omega 3-hydroxylase and omega 3-epoxygenase.
Characterization of the binding of thyroxine to high density lipoproteins and apolipoproteins A-I.
Pharmacokinetics and bioavailability of diclofenac in the rat.
Pharmacokinetics and biological availability of diclofenac preparations following intramuscular injection of 75 mg and oral administration of 150 mg of active drug
Human monocytes exposed to Biostim (RU 41740) alter lymphocyte mitogenesis: mechanisms of action.
Changes in regional renal blood flow after unilateral nephrectomy using the techniques of autoradiography and microautoradiography.
Diclofenac covalent protein binding is dependent on acyl glucuronide formation and is inversely related to P450-mediated acute cell injury in cultured rat hepatocytes.
Modulatory effect of bradykinin on noradrenaline release in isolated atria from normal and B2 knockout transgenic mice.
Potentiation of bradykinin by angiotensin-(1-7) on arterioles of spontaneously hypertensive rats studied in vivo.
Early discharge from hospital after open appendicectomy.
Glycogenolysis stimulation by non-steroidal anti-inflammatories in the perfused rat liver is not accompanied by Ca2+ release.
Acute anti-inflammatory activity and gastrointestinal tolerability of diclofenac and nitrofenac.
Effect of tenidap on cartilage integrity in vitro.
Drug action on articular cartilage surface. An in vitro study using mouse femoral heads labeled with cationized ferritin.
Effects of diclofenac on ceftriaxone pharmacokinetics in humans.
Indomethacin abolishes cerebral blood flow increase in response to acetazolamide-induced extracellular acidosis: a mechanism for its effect on hypercapnia?
Prostaglandin-induced changes and the influence of cyclo-and lipoxygenase inhibitors on the uterine collagen concentration in late pregnancy in rats.
Pharmacologic characteristics as the basis for differential therapy using non-steroidal anti-inflammatory agents
Preparation and characterization of multiple emulsion based systems for controlled diclofenac sodium release.
Enhancement of chemotherapeutic drug toxicity to human tumour cells in vitro by a subset of non-steroidal anti-inflammatory drugs (NSAIDs).
NMR microscopy of hydrating hydrophilic matrix pharmaceutical tablets.
Postoperative pain in children.
High-performance liquid chromatographic determination of usnic acid in plasma.
Altered pharmacodynamics of 1-(2-tetrahydrofuryl)-5-fluorouracil by pretreatment of rats with phenobarbital, indomethacin, diclofenac sodium and carbon tetrachloride.
High-performance liquid chromatography method for determination of flunixin in bovine plasma and pharmacokinetics after single and repeated doses of the drug.
High-performance liquid chromatographic determination of diclofenac in human plasma using automated column switching.
Vocalization response to close-arterial injection of bradykinin and other algesic agents in guinea pigs and its application to quantitative assessment of analgesic agents.
Alterations of filtration coefficients in pulmonary edema of different pathogenesis.
Possibilities of the combined use of non-steroidal anti-inflammatory drugs and sulfhydryl compounds in radioprotection.
Functional compartmentalization of arginine-vasopressin-activated cyclic AMP in anterior pituitary gland: the presence of a compartment activated by prostaglandin E2.
Use of chitosan in compressed tablets of diclofenac sodium: inhibition of drug release in an acidic environment.
Effect of diclofenac on human osteoblasts and their stromal precursors in vitro in relation to arthroplasty
Efficacy of diclofenac continuous perfusion in hyperalgic bone metastases. Apropos of 20 cases treated at Gustave Roussy Institute
Influence of gender on control of arterial tone in experimental hypertension.
(-)-Bay K 8644 liberates a contractant factor from the endothelium of the rat aorta.
Effect of diclofenac on corneal haze after photorefractive keratectomy in rabbits.
Altered hypoxia-induced coronary vasodilatation in diabetic rabbit heart.
Intracerebroventricularly administered bradykinin augments carrageenan-induced paw oedema in rats.
Transsynovial kinetics and correlation of dosage and effect of non-steroidal anti-rheumatic agents
Regulation of kinin-induced contraction and DNA synthesis by inflammatory cytokines in the smooth muscle of the rabbit aorta.
Formulation optimization of controlled release diclofenac sodium microspheres using factorial design.
Effects of tranilast on cultured rabbit corneal keratocytes and corneal haze after photorefractive keratectomy.
Terfenadine metabolism in human liver. In vitro inhibition by macrolide antibiotics and azole antifungals.
Prevention of alphaII(b)beta3 activation by non-steroidal antiinflammatory drugs.
Prostacyclin-dependent cyclic AMP formation in endothelial cells.
The effect of cyclooxygenase inhibitors on ion and water transport in the human kidney and frog skin and bladder
Conversion of a cyclooxygenase (CO) inhibitor into a 5-lipoxygenase (LO) inhibitor: a general route to novel orally active anti-inflammatory and anti-allergy drugs.
Comparison of the cyclooxygenase-1 inhibitory properties of nonsteroidal anti-inflammatory drugs (NSAIDs) and selective COX-2 inhibitors, using sensitive microsomal and platelet assays.
Selective inhibition of cyclooxygenase 2.
Arginines 97 and 108 in CYP2C9 are important determinants of the catalytic function.
Roles of human hepatic cytochrome P450s 2C9 and 3A4 in the metabolic activation of diclofenac.
cDNA-expressed human cytochrome P450 isozymes. Inactivation by porphyrinogenic xenobiotics.
Mechanisms of decrease in cytoplasmic motility of alveolar macrophages during immediate asthmatic response in dogs.
Predictive factors in advanced cancer pain treated only by analgesics.
Mechanisms of hydroperoxide-induced broncho- and vasoconstriction in isolated and perfused rat lung.
Spontaneous reporting of adverse drug reactions to non-steroidal anti-inflammatory drugs. A report from the Spanish System of Pharmacovigilance, including an early analysis of topical and enteric-coated formulations.
X-ray fluorescence determination of bromine traces in pharmaceutical formulations containing sodium diclofenac.
The effects of a newly developed nonsteroidal anti-inflammatory drug (M-5011) on arachidonic acid metabolism in rheumatoid synovial fibroblasts.
Diclofenac/N-(2-hydroxyethyl)pyrrolidine: a new salt for an old drug.
Mechanisms of protection afforded by cyclooxygenase inhibitors to endothelial function against ischemic injury in rat isolated hearts.
Cyclooxygenase inhibitors affect Met-enkephalin- and acetylcholine-stimulated motility of the isolated rat colon.
Effect of Feloran (diclofenac sodium) on the oxidative phosphorylation of rat liver mitochondria.
Pharmacokinetics of diclofenac and five metabolites after single doses in healthy volunteers and after repeated doses in patients.
Pharmacokinetics of diclofenac sodium using a developed HPLC method.
Biotransformation of diclofenac sodium (Voltaren) in animals and in man. I. Isolation and identification of principal metabolites.
The iron-binding and hydroxyl radical scavenging action of anti-inflammatory drugs.
Clinical efficacy of diclofenac sodium on postsurgical inflammation after intraocular lens implantation.
Absorption of sodium diclofenac after ocular administration in rabbit.
Aqueous solubility of diclofenac diethylamine in the presence of pharmaceutical additives: a comparative study with diclofenac sodium.
Inhibitory effects of diclofenac and indomethacin on interleukin-1-induced changes in PGE2 release. A novel effect on free arachidonic acid levels in human synovial cells.
Different effects of diclofenac and ketoprofen on the bactericidal action of polynuclear neutrophils in rheumatoid polyarthritis
Inhibitory effects of diclofenac on the endotoxin shock response in relation to endothelin turnover in the pig.
Uncoupling effects of diclofenac and aspirin in the perfused liver and isolated hepatic mitochondria of rat.
Determination of serum diclofenac by high-performance liquid chromatography by electromechanical detection.
Metabolic activation of diclofenac by human cytochrome P450 3A4: role of 5-hydroxydiclofenac.
Effect of indomethacin, diclofenac sodium and sodium salicylate on peripheral blood cell counts in sublethally gamma-irradiated mice.
Delayed contact hypersensitivity to non-steroidal anti-inflammatory drugs.
Effect of ibuprofen and diclofenac on the chemotaxis induced by substance P and transforming growth factor-beta on human monocytes and polymorphonuclear cells.
The effect of orthofen (diclofenac) on the embryogenesis of laboratory mice
Antipyretic therapy with diclofenac sodium. Observations on effect and serious side effects in critically ill patients.
Chitosan microspheres of diclofenac sodium, II: In vitro and in vivo evaluation.
Percutaneous transport of diclofenac sodium from mixtures of fatty alcohol (or fatty acid) and propylene glycol through the rabbit abdominal skin.
Identification of two different rate-limiting mechanisms controlling the release of NSAIDs from silastic polymeric devices, and possible implications.
Hyperpolarization-induced dilatation of submucosal arterioles in the guinea-pig ileum.
Survey of antiinflammatory agents and related drugs as inhibitors of ovulation in the rabbit.
Influence of laparotomy on disposition kinetics of diclofenac in CCl4-intoxicated rats.
Patterns of rheumatic diseases and antirheumatic drug usage in 11931 Indian patients.