Drugs online research references
Sven Lakartidn. 1962 Feb 8;59:392-404.
[Clinical trials with amitriptyline with special attention to the possible occurrence of toxic action on blood count and liver function]
[Article in Swedish]
JANSSON B, HOLMBERG MB.
PMID: 14451244 [PubMed - OLDMEDLINE for Pre1966]
Scand J Clin Lab Invest. 1976 Jan;36(1):17-21.
The effect of amitriptyline on forearm blood flow.
Thorstrand C, Lindblad LE.
The local effect of intra-arterial infusion of amitriptyline (AT) on forearm blood flow was studied in seven healthy subjects. AT was infused at rates of 0.05, 0.10, 0.15, and 0.20 mg-min--1 for periods of 5 min. Forearm blood flow showed a dose-dependent increase when the dose exeeded 0.10 mg-min--1. On the highest dose level the blood flow increased on an average by 73%. No systemic effects, as reflected by changes in heart rate, blood pressure, and blood flow in the contralateral forearm, were observed during the infusion. The present data indicate a dilatating effect of AT on resistance vessels possibly mediated by an alpha-adrenergic blockade.
online pharmacy ref source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1257692&dopt=Abstract
Biochem Pharmacol. 1964 Dec;13:1683-5.
THE EFFECT OF AMITRIPTYLINE ON GLYCOGEN PHOSPORYLASE IN CARDIAC MUSCLE.
SATCHELL DG, CAIRNCROSS KD, FREEMAN SE.
PMID: 14248399 [PubMed - OLDMEDLINE for Pre1966]
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