Drugs online research references






Acta Med Leg Soc (Liege). 1985;35(1):59-63.
Amitriptyline and its metabolites: blood and urine levels in overdose.

Fagarasan M, Fagarasan E, Quai I, Toma T, Florescu A.

PMID: 2979900 J Clin Invest. 1981 May;67(5):1500-6.
Inhibition of riboflavin metabolism in rat tissues by chlorpromazine, imipramine, and amitriptyline.

Pinto J, Huang YP, Rivlin RS.

PMID: 6262379


J Assoc Off Anal Chem. 1985 Mar-Apr;68(2):168-71.
Liquid chromatographic method for identity, assay, and content uniformity of five tricyclic drugs.

Lovering EG, Beaulieu N, Lawrence RC, Sears RW.

A liquid chromatographic (LC) procedure has been developed for the assay, content uniformity, and identification of single active ingredient solid and liquid formulations of amitriptyline, chlorpromazine, imipramine, thioridazine, and trifluoperazine. The drugs are extracted from their formulations with methanol or dilute hydrochloric acid, and identified by comparison of retention times with those of known standards; drugs are quantitated against these standards with dl-norephedrine hydrochloride as the internal standard. The precision of replicate injections is better than 2.5% for peak area and better than 1% for peak height. The precision of triplicate determinations of tablet composites is better than 2.2%.

online pharmacy ref source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2859267&dopt=Abstract













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