Ambien online research references









  • Changes in GABA(A) receptor gene expression induced by withdrawal of, but not by long-term exposure to, zaleplon or zolpidem.
  • Mechanism of alpha-subunit selectivity of benzodiazepine pharmacology at gamma-aminobutyric acid type A receptors.
  • Selective modulation of tonic and phasic inhibitions in dentate gyrus granule cells.
  • Anxiolytic-like effects of acute and chronic GABA transporter inhibition in rats.
  • Functional characterization of GABA(A) receptors in neonatal hypothalamic brain slice.
  • Zolpidem in restless legs syndrome.
  • Selective antagonism of the ataxic effects of zolpidem and triazolam by the GABAA/alpha1-preferring antagonist beta-CCt in squirrel monkeys.
  • Altered kinetics and benzodiazepine sensitivity of a GABAA receptor subunit mutation gamma 2(R43Q) found in human epilepsy.
  • Mechanism-based pharmacodynamic modeling of the interaction of midazolam, bretazenil, and zolpidem with ethanol.
  • Effect of zolpidem on human cytochrome P450 activity, and on transport mediated by P-glycoprotein.
  • Transduction of the discriminative stimulus effects of zolpidem by GABA(A)/alpha1 receptors.
  • Temazepam, but not zolpidem, causes orthostatic hypotension in astronauts after spaceflight.
  • Physicochemical characterization and in vivo properties of Zolpidem in solid dispersions with polyethylene glycol 4000 and 6000.
  • Determination of zaleplon and zolpidem by liquid chromatography-turbo-ionspray mass spectrometry: application to forensic cases.
  • Differential effects in humans after repeated administrations of zolpidem and triazolam.
  • Prenatal protein malnutrition results in increased frequency of miniature inhibitory postsynaptic currents in rat CA3 interneurons.
  • Imidazopyridines, an alternative to benzodiazepines
  • Lack of tolerance and physical dependence upon repeated treatment with the novel hypnotic zolpidem.
  • Major differences in inhibitory synaptic transmission onto two neocortical interneuron subclasses.
  • Limited anxiolytic-like effects of non-benzodiazepine hypnotics in rodents.
  • Specific GABAA circuits for visual cortical plasticity.
  • Incremental conductance levels of GABAA receptors in dopaminergic neurones of the rat substantia nigra pars compacta.
  • Inappropriate medication prescribing in homebound older adults.
  • Differential ontogenesis of type I and II benzodiazepine receptors in mouse cerebellum.
  • Efficacy of a new hypnotic zolpidem (Stilnox) in ambulatory practice (Cooperative study by practitioners in Geneva, Lausanne and Tessin)
  • Zolpidem involvement on memory and hypnotic effect of ethanol in chronically ethanol-treated rats.
  • Zolpidem excretion in breast milk.
  • Clonazepam selectively increases saccharin ingestion in a two-choice test.
  • Zolpidem, a novel nonbenzodiazepine hypnotic. I. Neuropharmacological and behavioral effects.
  • High affinity 3Hzolpidem binding in the rat brain: an imidazopyridine with agonist properties at central benzodiazepine receptors.
  • Further behavioural evidence for the selective sedative action of zolpidem.
  • Investigation of the development of tolerance to the actions of zolpidem and midazolam.
  • Independence of sleep EEG responses to GABAergic hypnotics: biological implications.
  • Regional differences in the effects of chronic ethanol administration on 3Hzolpidem binding in rat brain.
  • Modulation of 35STBPS binding by ligands with preferential affinity for benzodiazepine BZ1 sites in the cerebral cortex of newborn and adult rats.
  • Distribution of 3Hzolpidem binding sites in relation to messenger RNA encoding the alpha 1, beta 2 and gamma 2 subunits of GABAA receptors in rat brain.
  • Effect of the benzodiazepine receptor agonist, zolpidem, on palatable fluid consumption in the rat.
  • Screening, identification and determination of the two new hypnotics zolpidem and zopiclone.
  • Pharmacokinetics and brain distribution of zolpidem in the rat after acute and chronic administration.
  • Participation of mitochondrial diazepam binding inhibitor receptors in the anticonflict, antineophobic and anticonvulsant action of 2-aryl-3-indoleacetamide and imidazopyridine derivatives.
  • Regional changes in 3Hzolpidem binding to brain benzodiazepine receptors in flurazepam tolerant rat: comparison with changes in 3Hflunitrazepam binding.
  • New drugs from 1991-1992.
  • Direct determination of zolpidem and its main metabolites in urine using capillary electrophoresis with laser-induced fluorescence detection.
  • Comparative study of effects of ivadal and rodedorm in insomnia in structure of borderline mental diseases
  • Acute overdose of Zolpidem (Stilnox)
  • Progressive elevation of plasma thyrotropin during adaptation to simulated jet lag: effects of treatment with bright light or zolpidem.
  • Pharmacologic actions of subtype-selective and novel GABAergic ligands in rat lines with differential sensitivity to ethanol.
  • GABAA and NMDA receptor subunit mRNA expression in ethanol dependent rats.
  • Differential epilepsy-associated alterations in postsynaptic GABA(A) receptor function in dentate granule and CA1 neurons.
  • Zolpidem binding sites on the GABA(A) receptor in brain from human cirrhotic and non-cirrhotic alcoholics.
  • Treatment of insomnia in patients with borderline mental diseases
  • Differences between BDZ1 selective and non-selective GABAA/BDZ receptor ligands in discriminative stimulus and EtOH intake/preference paradigms.
  • 3Hzolpidem binding in alcohol-preferring and non-preferring rat brain.
  • SB-205384: a GABA(A) receptor modulator with novel mechanism of action that shows subunit selectivity.
  • Identification of amino acid residues responsible for the alpha5 subunit binding selectivity of L-655,708, a benzodiazepine binding site ligand at the GABA(A) receptor.
  • GABAA receptor pharmacology and subtype mRNA expression in human neuronal NT2-N cells.
  • Safety and tolerance of zolpidem in the treatment of disturbed sleep: a post-marketing surveillance of 16944 cases.
  • Combination of open field and elevated plus-maze: a suitable test battery to assess strain as well as treatment differences in rat behavior.
  • Action of ethanol and zolpidem on gamma-aminobutyric acid responses from cerebellar Purkinje neurons: relationship to beta-adrenergic receptor input.
  • Cardiac effects of benzodiazepine receptor agonists and antagonists in the isolated rat heart: a comparative study.
  • Developmental change of GABA(A) receptor-mediated current in rat hippocampus.
  • Changes in 3Hzolpidem and 3HRo 15-1788 binding in rat globus pallidus and substantia nigra pars reticulata following a nigrostriatal tract lesion.
  • Effects of buspirone, diazepam, and zolpidem on open field behavior, and brain 3Hmuscimol binding after buspirone pretreatment.
  • Benzodiazepine tolerance at GABAergic synapses on hippocampal CA1 pyramidal cells.
  • A structure-activity relationship study of the affinity of selected imidazo1,2-apyridine derivatives, congeners of zolpidem, for the omega 1-subtype of the benzodiazepine receptor.
  • Different types of GABA(A) receptors may mediate the anticonflict and response rate-decreasing effects of zaleplon, zolpidem, and midazolam in squirrel monkeys.
  • Prediction of human hepatic clearance from in vivo animal experiments and in vitro metabolic studies with liver microsomes from animals and humans.
  • Diminished allopregnanolone enhancement of GABA(A) receptor currents in a rat model of chronic temporal lobe epilepsy.







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