Drugs online research references
Cardiac contractile injury after intestinal ischemia-reperfusion.
Renal insufficiency after heart transplantation: a case-control study.
Susceptibility of Helicobacter pylori to simethicone and other non-antibiotic drugs.
Role of superoxide in hemorrhagic shock-induced P-selectin expression.
Zonal heterogeneity of hepatic injury following shock/resuscitation: relationship of xanthine oxidase activity to localization of neutrophil accumulation and central lobular necrosis.
Optimization of a high-performance liquid chromatographic method for the determination of nucleosides and their catabolites. Application to cat and rabbit heart perfusates.
Reoxygenation injury in rat hepatocytes: mediation by O2/H2O2 liberated by sources other than xanthine oxidase.
The effect of supplementing hypothermic crystalloid cardioplegia with catalase plus allopurinol in the isolated rabbit heart.
Kinetics of allopurinol after single intravenous and oral doses. Noninteraction with benzbromarone and hydrochlorothiazide.
Allopurinol kinetics in humans as a means to assess liver function: evaluation of an allopurinol loading test.
Activation of drug-specific CD4+ and CD8+ T cells in individuals allergic to sulfonamides, phenytoin, and carbamazepine.
PCR follow-up examination after treatment of canine leishmaniosis (CaL).
NADH oxidase activity of human xanthine oxidoreductase--generation of superoxide anion.
Acetaminophen inhibits the human polymorphonuclear leukocyte function in vitro.
Inhibitory action of hydrogen peroxide on a high-resistance epithelium.
Mannitol reduces plasma hydrogen peroxide free radical in patients undergoing coronary artery bypass graft surgery
Drug-induced and genetic hypermelanism: effects on pigment cell differentiation.
Studies on the cause of hyperuricosuria in cystic fibrosis patients.
Tienilic acid in hypertension with hyperuricaemia.
The treatment of hyperuricemia after kidney transplantation
Hematuria due to hyperuricosuria in children: 36-month follow-up.
The effect of antioxidative combination therapy on post hypoxic-ischemic perfusion, metabolism, and electrical activity of the newborn brain.
Correlation of results of agglutination assays with concanavalin A and carcinogenesis experiments on promoters of bladder cancer.
A comparative study on the hypouricemic activity and potency in renal xanthine calculus formation of two xanthine oxidase/xanthine dehydrogenase inhibitors: TEI-6720 and allopurinol in rats.
Kinetic mechanism of human hypoxanthine-guanine phosphoribosyltransferase: rapid phosphoribosyl transfer chemistry.
Effect of allopurinol on hypoxia-induced modification of the NMDA receptor in newborn piglets.
Effects of supplementing hypothermic crystalloid cardioplegic solution with catalase, superoxide dismutase, allopurinol, or deferoxamine on functional recovery of globally ischemic and reperfused isolated hearts.
Simultaneous assay of hypoxanthine, xanthine and allopurinol by high-performance liquid chromatography and activation of immobilized xanthine oxidase as an enzyme reactor.
Absence of hypoxanthine:guanine phosphoribosyltransferase activity in murine Dunn osteosarcoma.
Reduction of perinatal hypoxic-ischemic brain damage with allopurinol.
Clinical significance of hyperuricaemia in medically-hospitalized women over 50 years of age
Activity of purine analogs against Leishmania donovani in vivo.
Inhibition of Trypanosoma cruzi growth in mammalian cells by purine and pyrimidine analogs.
A study of the immunosuppressive effect of allopurinol.
Evidence for lack of importance of oxygen free radicals in Escherichia coli endotoxemia in dogs.
Educational program to improve the dosage prescribing of allopurinol.
Electroconvulsive shock increases interstitial concentrations of uric acid in the rat brain.
Gastric mucosal damage induced by compound 48/80: roles of serotonin and nitric oxide.
Toxic oxygen metabolites induce vasoconstriction and bronchoconstriction in isolated, plasma-perfused rat lungs.
Allopurinol: kinetics, inhibition of xanthine oxidase activity, and protective effect in ischemic-reperfused canine heart as studied by cardiac microdialysis.
Nitric oxide exposure inhibits endothelial NOS activity but not gene expression: a role for superoxide.
Role of xanthine oxidase inhibition in survival from hemorrhagic shock.
Prevention of reperfusion injury in surgically induced gastric dilatation-volvulus in dogs.
Antioxidants protect cultured bovine lung endothelial cells from injury by endotoxin.
Prevention of ischemic injury in hepatocellular transplant in the rat
Experimental study of injury on the small intestine in acute portal vein occlusion and the following restoration of portal vein flow in rats--hemodynamics and lipid peroxidation
Quality use of allopurinol in the elderly.
The effects of allopurinol in hepatic ischemia and reperfusion: experimental study in rats.
Allopurinol challenge test in children.
Xanthine oxidase inhibitor in acute experimental pancreatitis in rats and mice.
Allopurinol and lodoxamide in complement-induced hepatic ischemia.
Rat intestinal peroxidase: inhibition by endogenous xanthine and xanthine oxidase.
Anticonvulsant effect of allopurinol on hippocampal-kindled seizures.
Role of lipid peroxidation in gastric mucosal lesions induced by ischemia-reperfusion in the pylorus-ligated rat.
Xanthine oxidase mediates cyclic flow variations in a canine model of coronary arterial thrombosis.
Effects of diltiazem and allopurinol in postischemic microcirculatory changes in the rat kidney.
Hyperuricemia and renal insufficiency associated with malignant disease: urate oxidase as an efficient therapy?
Reactive oxygen intermediates reduce inactivation of serotonin in isolated, perfused rat lungs.
Peroxide-cyclooxygenase interactions in postasphyxial changes in retinal and choroidal hemodynamics.
Drug-induced acute interstitial nephritis: report of 10 cases.
Allopurinol prevents intestinal permeability changes after ischemia-reperfusion injury.
Behavior of N-methylated allopurinols and related 4-thioxopyrazolo 3,4-dpyrimidines towards bovine milk xanthine oxidase.
Phagocytosis of intravenously administered particles by leukocytes adhered to the aortic endothelium of the rat.
Effect of oxipurinol and allopurinol riboside on whewellite crystallization: in vitro and in vivo observations.
Determination of plicamycin in plasma by radioimmunoassay.
Identification of a cytogenetic deletion and of four novel mutations (Q69X, I172F, G188V, G197R) affecting the gene for ornithine transcarbamylase (OTC) in Spanish patients with OTC deficiency.
Sequence of gastric mucosal injury following ischemia and reperfusion. Role of reactive oxygen metabolites.
Methyldopa binding to cells in culture.
Allopurinol-induced effects in premature baboons with respiratory distress syndrome.
Studies on the mechanism of immunosuppression with adenine.
Ultrastructural alterations in ovaries from nifurtimox or benznidazole-treated rats: their relation to ovarian nitroreductive biotransformation of both drugs.
Contracture and cell damage in calcium paradox is not caused by lipid peroxidation.
Purine efflux after cardiac ischemia: relevance to allopurinol cardioprotection.
Endothelin-1-induced oedema in rat and guinea-pig isolated perfused lungs.
Nicotine and gastric ulcers in stress.
Effect of DL-sodium lactate infusion on excretion of purine bases and oxypurinol.
Gastric mucosal cytoprotection in the rat by scavenging oxygen-derived free radicals.
Allopurinol reduced hepatic ischemia-reperfusion injury exacerbated by inhalation of high-concentration oxygen in rats.
An ultrastructural study to investigate the effect of allopurinol on cerulein-induced damage to pancreatic acinar cells in rat.
Allopurinol prevents ischaemia-dependent haemorheological changes.
Attenuation of renal ischemia-reperfusion injury in rats by allopurinol and prostaglandin E1.
Microvascular ischemia-reperfusion injury in striated muscle: significance of "no reflow".
Attenuation of ischemia-reperfusion injury of the liver in dogs by cyclosporine. A comparative study with allopurinol and methylprednisolone.
Acute mesenteric ischemia/reperfusion down regulates renal PGE2 synthesis.
Prophylactic effect of allopurinol mouthwash against stomatitis induced by the chemotherapy (PMUE regimen) for gastrointestinal malignancies
Effect of allopurinol on ischemia and reperfusion-induced cerebral injury in spontaneously hypertensive rats.
Synthesis of uric acid in isolated normothermic perfused mongrel and Dalmatian dog kidneys.
Xanthine oxidoreductase activity in rat brain tissue: the changes after decapitation
Sixty minutes normothermic ischemia in rat liver: the declining tissue concentration of hypoxanthine during reperfusion is not a washout phenomenon.
Role of oxygen radicals in ischemia-induced lesions in the cat stomach.
Breakdown of hepatic tight junctions during reoxygenation injury.
Combination therapy in Kala-azar.
The allopurinol load test lacks specificity for primary urea cycle defects but may indicate unrecognized mitochondrial disease.
Experimental visceral leishmaniasis: role of trans-aconitic acid in combined chemotherapy.
Effect of antioxidants on L-glutamate and N-methyl-4-phenylpyridinium ion induced-neurotoxicity in PC12 cells.
Oxygen free radicals and lipid peroxidation in the pathogenesis of gastric mucosal lesions induced by indomethacin in rats. Relation to gastric hypermotility.
Role of free radicals and lipid peroxidation in gastric mucosal injury induced by ischemia-reperfusion in rats
Allopurinol effects in rat liver transplantation on recovery of energy metabolism and free radical-induced damage.
Inhibition of orotidylate decarboxylase by 4(5H)-oxo-1-beta-D-ribofuranosylpyrazolo3,4-d pyrimidine-3-thiocarboxamide (APR-TC) in B lymphoblasts. Activation by adenosine kinase.
Short-term exposure to lipopolysaccharide is associated with microvascular contractile dysfunction in vivo.
Reversed-phase liquid-chromatographic determination of purine compounds in serum applied to studies of hypouricemia.
Drug-induced urinary lithiasis
Ischemic damage of the liver. Part II: In vivo investigation of the prevention of the ischemic lesion of the liver.
Immunocytochemical localization of xanthine oxidase in rat myocardium.
The use of allopurinol in long-term treatments for optimal effect
Oxidative modification of low-density lipoprotein by the human hepatoma cell line HepG2.
Purine metabolic enzymes in lymphocytes. IV. Effects of enzyme inhibitors and enzyme substrates on the blastogenic responses of human lymphocytes.
Increased production of luminol enhanced chemiluminescence by the inflamed colonic mucosa in patients with ulcerative colitis.
Xanthine oxidase is not a major source of free radicals in focal cerebral ischemia.
Free oxygen radicals decrease electrical resistance of microvascular endothelium in brain.
Therapeutic effect of Leo 1031, an alkylating corticosteroid ester, in lymphoproliferative disorders. I. chronic lymphocytic leukaemia.
Protection afforded by allopurinol in the first 24 hours of coronary occlusion is diminished after 48 hours.
Theobromine metabolism in man.
Allopurinol kinetics after massive overdosage.
Investigations into the mechanism of toxicity of lipopolysaccharide (LPS) in bovine aortic endothelial cells.
Experiments on the medicamental treatment of the noise-induced cochlear damage. Part I. The effect of dipyridamol and allopurinol on the RMP of the cochlea (guinea pig) after noise
Free radical scavengers in mercuric chloride-induced acute renal failure in the rat.
3,3',5-triiodothyronine-induced hepatic respiration: effects of desferrioxamine and allopurinol in the isolated perfused rat liver.
Hypouricemic effect of allopurinol and the novel xanthine oxidase inhibitor TEI-6720 in chimpanzees.
Pyrazolopyrimidine metabolism in African trypanosomes: metabolic similarities to Trypanosoma cruzi and Leishmania spp.
Stone composition and metabolic study in urinary calculous disease.
Enzymatic antioxidant defence mechanism in rat intestinal tissue is changed after ischemia-reperfusion. Effects of an allopurinol plus antioxidant combination.
In vitro differential metabolism of merbarone by xanthine oxidase and microsomal flavoenzymes. The role of reactive oxygen species.
Prophylactic action of allopurinol against chemotherapy-induced stomatitis--inhibition of superoxide dismutase and proteases.
Changes in theophylline metabolism during postnatal development in rat liver slices.
Inhibition of transition metal ion-catalysed ascorbate oxidation and lipid peroxidation by allopurinol and oxypurinol.
Inhibition of first-pass metabolism in cancer chemotherapy: interaction of 6-mercaptopurine and allopurinol.
Urinary excretion of methylated purines in man and in the rat after the administration of theophylline.
Effect of an allopurinol/benzbromaron preparation on the composition of urine in a circadian course
Failure of allopurinol to modify urinary composition in enteric hyperoxaluria.
The genetic control of the molybdoflavoproteins in Aspergillus nidulans. IV. A comparison between purine hydroxylase I and II.
Macrophage cell-conditioned medium promotes cholinergic differentiation of undifferentiated progenitors and synergizes with nerve growth factor action in the developing basal forebrain.
Role of xanthine dehydrogenase and oxidase in focal cerebral ischemic injury to rat.
On drug artifacts in middle molecule analysis.
Ascorbate preserves gastric mucosal metabolism and microcirculation after hemorrhagic shock and retransfusion in rats.
Inhibition of mucopolysaccharide sulfation.
Genetic susceptibility to mucosal damage leads to bacterial translocation in a murine burn model.
Coronary vascular smooth muscle function in E. coli endotoxemia in dogs.
Altered specificity mutations define residues essential for substrate positioning in xanthine dehydrogenase.
Xanthine oxidase-mediated mutagenicity of the bladder carcinogen 4-nitrobiphenyl.
Allopurinol improves myocardial reperfusion injury in a xanthine oxidase-free model.
Effect of allopurinol on myocardial recovery during reperfusion.
Effect of N-acetyl-L-cysteine on sepsis in mice.
Structure-function dependence and allopurinol inhibition of radiosensitizer/nitroreductase interaction: approaches to improving therapeutic ratios.
Drugs, food additives and natural products as promoters in rat urinary bladder carcinogenesis.
Toxic epidermal necrolysis.
Idiopathic calcium nephrolithiasis: therapeutic aspects
Gout and uric acid nephropathy: some new aspects in diagnosis and treatment.
Xanthine oxidase promotes neutrophil sequestration but not injury in hyperoxic lungs.
Azathioprine toxicity in neuromuscular disease.
Role of mast cells, neutrophils and nitric oxide in endotoxin-induced damage to the neonatal rat colon.
Identification of an N-hydroxyguanidine reducing activity of xanthine oxidase.
Mitigation of nitrofurantoin-induced toxicity in the perfused rat lung.
Studies on nifurtimox nitroreductase activity in liver and other rat tissues.
A mutation in the xanthine dehydrogenase (purine hydroxylase I) of Aspergillus nidulans resulting in altered specificity. Implications for the geometry of the active site.
Lung injury in Fischer but not Sprague-Dawley rats after short-term hyperoxia.
Clearance of oxypurines in normal subjects and in gout patients subjected to a purine-free diet. Effects of allopurinol
WY-14 643 rapidly activates nuclear factor kappaB in Kupffer cells before hepatocytes.
Inhibition of purine nucleoside phosphorylase activity and of T-cell function with allopurinol-riboside.
Catabolism of adenine nucleotides in suspension-cultured plant cells.
Xanthine oxidase produces O2-. in posthypoxic injury of renal epithelial cells.
Flow cytometric assessment of allopurinol susceptibility in Leishmania infantum promastigote.
Studies on the specificity of the effects of oxygen metabolites on cardiac sodium pump.
Concomitant administration of 4-hydroxypyrazolopyrimidine (allopurinol) and high-dose continuous infusion 5-fluorouracil.
Quantitative determination of some pharmaceuticals in bulk drugs and tablets by proton magnetic resonance (PMR) spectroscopy.
Metabolism of azoxy derivatives of procarbazine by aldehyde dehydrogenase and xanthine oxidase.
Reduction of oral toxicity of 5-fluorouracil by allopurinol mouthwashes.
Lack of photosensitization of ocular tissues by allopurinol.
Electron microscopic study of leaf frog melanophore differentiation in culture, with special reference to allopurinol effect on pterorhodin formation.
Value of repeated analyses of 24-hour urine in recurrent calcium urolithiasis.
Mechanism of the formation of megamitochondria in the mouse liver induced by chloramphenicol.
The effect of allopurinol on hemodynamic, respiratory and biochemical functional values in health persons following oral administration
The effect of allopurinol on the synthesis of adenine nucleotides and ribonucleic acid from inosine via a salvage pathway in the brain of rats
Effect of glucose infusion on the renal transport of purine bases and oxypurinol.
The effects of allopurinol on the ultrastructure of ischaemic and reperfused large intestine of sheep.
Efficacy of 15-(123I)-p-iodophenyl pentadecanoic acid (IPPA) in assessing myocardial metabolism in a model of reversible global ischemia.
In vivo electrochemical detection of 5-hydroxyindoles in the dorsal horn of the spinal cord: the contribution of uric acid to the voltammograms.
The influx of uric acid and other purines into everted jejunal sacs of the rat and hamster.
Mannitol, but not allopurinol, modulates changes in cerebral blood flow, intracranial pressure, and brain water content during pneumococcal meningitis in the rat.
Existence and participation of xanthine oxidase in reperfusion injury of ischemic rabbit myocardium.
The involvement of reactive oxygen species in hypoxic injury to rat liver.
Kinetics of allopurinol and oxipurinol after chronic oral administration. Interaction with benzbromarone.
Purification and properties of purine hydroxylase II from Aspergillus nidulans.
The optimal use of allopurinol: an audit of allopurinol use in South Auckland.
Circulating plasma xanthine oxidase contributes to vascular dysfunction in hypercholesterolemic rabbits.
Asymptomatic and late-onset ornithine transcarbamylase (OTC) deficiency in males of a five-generation family, caused by an A208T mutation.
Effect of inline filtration on ViaSpan cold-storage solution.
Reduction of 2,4-dinitrotoluene by Wistar rat liver microsomal and cytosol fractions.
The urinary excretion of orotic acid and orotidine, measured by an isotope dilution assay.
Inhibition of calcium oxalate crystal growth in urine during treatment with allopurinol.
Propranolol as xanthine oxidase inhibitor: implications for antioxidant activity.
Role of xanthine oxidase-derived oxidants and leukocytes in ethanol-induced jejunal mucosal injury.
Inhibition of xanthine oxidase and xanthine dehydrogenase by nitric oxide. Nitric oxide converts reduced xanthine-oxidizing enzymes into the desulfo-type inactive form.
Inhibition of xanthine oxidase-xanthine-iron mediated lipid peroxidation by eugenol in liposomes.
Acetaminophen-induced oxidation of protein thiols. Contribution of impaired thiol-metabolizing enzymes and the breakdown of adenine nucleotides.
Potentiation of nitric oxide-mediated vasorelaxation by xanthine oxidase inhibitors.
Xanthine:acceptor oxidoreductase activities in ischemic rat skin flaps.
Minimal role of xanthine oxidase and oxygen free radicals in rat renal tubular reoxygenation injury.
Chronic orchialgia. A diagnostic and therapeutic hypothesis
Effect of allopurinol on oxidant stress and hepatic function following ischemia and reperfusion in the rat.
Murine epidermal xanthine oxidase activity: correlation with degree of hyperplasia induced by tumor promoters.
Sustained reductions in oxipurinol renal clearance during a restricted diet.
Scavengers of free radical oxygen affect the generation of low molecular weight DNA in stimulated lymphocytes from patients with systemic lupus erythematosus.
Fluorographic study on the oxidative stress in the process of gastric mucosal injury: attenuating effect of vitamin E.
Involvement of oxygen-derived free radicals in L-arginine-induced acute pancreatitis.
Investigation of oxygen-derived free radical generation in cancellous bone specimens obtained from dogs.
The permissive role of oxygen-derived free radicals in the development of colonic cancer in the rat. A new theory for carcinogenesis.
Effects of ischemia and oxygen radicals on mucosal albumin clearance in intestine.
The inhibitory action of oxygen radical scavengers on proteinuria and glomerular heparan sulphate loss in the isolated perfused kidney.
Effect of diethyldithiocarbamate on gastric and duodenal mucosal blood flow and vascular permeability in rats.
Participation of reactive oxygen metabolites in Clostridium difficile toxin A-induced enteritis in rats.
Preservation-induced pancreatitis in an isolated perfused pancreas model in the dog.
Trypanosoma cruzi: 4-aminopyrazolopyrimidine in the treatment of experimental Chagas' disease.
Visceral leishmaniasis in patients with HIV infection
Investigation of possible participation of nucleoside transport systems in the postischemic release of purines and pyrimidines from cold stored liver.
Reperfusion injury pathophysiology in sickle transgenic mice.
Urine composition in patients with renal stone disease during treatment with allopurinol.
Care of the hemodialysis patients by the family physician
Effects of exercise performance on drugs used in musculoskeletal disorders.
Early postburn lipid peroxidation: effect of ibuprofen and allopurinol.
Effect of allopurinol on different strains of Trypanosoma cruzi.
Complexes of poly(adenylic acid) with complementary monomers.
Additive effect of allopurinol and deferoxamine in the prevention of spinal cord injury caused by aortic crossclamping.
Changes in macromolecular permeability of microvessels in rat small intestine after total occlusion ischemia/reperfusion.
The clinical pharmacokinetics of allopurinol. 1. Allopurinol absorption sites and dose proportionality of allopurinol/oxipurinol bioavailability
Pathophysiology and pharmacology of reactive oxygen species in inflammation
Phase I and clinical pharmacological study of mercaptopurine administered as a prolonged intravenous infusion.
Statistical methods in pharmacoepidemiology. Principles in managing error.
Mice with adenine phosphoribosyltransferase deficiency develop fatal 2,8-dihydroxyadenine lithiasis.
Erythrocyte purine phosphoribosyltransferase activity in girls with the Lesch-Nyhan syndrome
Kinetics of high-energy phosphates in allopurinol-pretreated ischaemic and post-ischaemic skeletal muscle: an in vivo magnetic resonance spectroscopy study.
Role of free radicals and platelet-activating factor in the genesis of intestinal motor disturbances induced by Escherichia coli endotoxins in rats.
Inactivation of heart dihydrolipoamide dehydrogenase by copper Fenton systems. Effect of thiol compounds and metal chelators.
Involvement of platelet-activating factor (PAF) in endotoxin- or ischaemia-induced intestinal hyperpermeability in the rat.
Superoxide-independent platelet response to xanthine oxidase.
Reactive oxygen species play an important role in the activation of heat shock factor 1 in ischemic-reperfused heart.
Value of Western blotting in the clinical follow-up of canine leishmaniasis.
The influence of allopurinol on kidney haemodynamic and excretory responses to renal ischaemia in anaesthetized rats.
Purine nucleotide metabolism in promastigotes of Leishmania tropica: inhibitory effect on allopurinol and analogues of purine nucleosides.
Xanthine oxidase contributes to host defense against Burkholderia cepacia in the p47(phox-/-) mouse model of chronic granulomatous disease.
Interaction between allopurinol and pyrazinamide.
Role of stasis and oxidative stress in ileal pouch inflammation.
Rhinovirus-induced oxidative stress and interleukin-8 elaboration involves p47-phox but is independent of attachment to intercellular adhesion molecule-1 and viral replication.
Allopurinol and dimethylthiourea reduce brain infarction following middle cerebral artery occlusion in rats.
Clinical results of allopurinol treatment in prevention of calcium oxalate stone formation.
Effect of ozone treatment on reactive oxygen species and adenosine production during hepatic ischemia-reperfusion.
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Vascular and hepatocellular peroxynitrite formation during acetaminophen toxicity: role of mitochondrial oxidant stress.
Pharmacokinetics of allopurinol in Dalmatian dogs.
Changes of gastric lipase activity after ethanol and indomethacin administration: influence of pretreatment with allopurinol, pentoxifylline and L-DOPA.
A novel parasite-derived suicide gene for cancer gene therapy with specificity for lung cancer cells.
Development of a bacterial screen for novel hypoxanthine-guanine phosphoribosyltransferase substrates.
Effect of norepinephrine on the urinary excretion of purine bases and oxypurinol.
Vascular endothelial growth factor induces manganese-superoxide dismutase expression in endothelial cells by a Rac1-regulated NADPH oxidase-dependent mechanism.
Effect of superoxide dismutase and allopurinol on microcirculatory disturbances during burn shock
Effect of 4-hydroxypyrazolo3,4-dpyrimidine (allopurinol) administration of growth of Ehrlich tumor cells.
Urate oxidase in the prophylaxis or treatment of hyperuricemia: the United States experience.
Free radicals in hypoxic rat diaphragm contractility: no role for xanthine oxidase.
Oxidative stress in scleroderma: maintenance of scleroderma fibroblast phenotype by the constitutive up-regulation of reactive oxygen species generation through the NADPH oxidase complex pathway.
Identification and quantitation of purine derivatives in urinary calculi as markers of abnormal purine metabolism by using high-performance liquid chromatography (HPLC)
Protective effect of allopurinol and superoxide dismutase in renal isografts in cyclosporin A-treated rats.
Spinal cord metabolism during thoracic aortic cross-clamping in pigs with special reference to the effect of allopurinol.
In vivo assessment of free radical activity during shock wave lithotripsy using a microdialysis system: the renoprotective action of allopurinol.
The kinetics of hypoxanthine transport across the perfused choroid plexus of the sheep.
Oxidative stress induced cytokine production in isolated rat pancreatic acinar cells: effects of small-molecule antioxidants.
Effects of superoxide dismutase and allopurinol on the survival of acute island skin flaps.
Action of uric acid, allopurinol and oxypurinol on the myeloperoxidase-derived oxidant hypochlorous acid.
Manipulation of plasma uric acid in broiler chicks and its effect on leukocyte oxidative activity.
Modulation of radiation-induced changes in the xanthine oxidoreductase system in the livers of mice by its inhibitors.
Imbalance between xanthine oxidase and nitric oxide synthase signaling pathways underlies mechanoenergetic uncoupling in the failing heart.
Temporal efficacy of allopurinol during the induction of pancreatitis in the ex vivo perfused canine pancreas.
Beneficial effect of allopurinol in liver ischemia.
Oxygen-derived free radicals mediate endothelium-dependent contractions to acetylcholine in aortas from spontaneously hypertensive rats.
Hyperuricemia induces a primary renal arteriolopathy in rats by a blood pressure-independent mechanism.
Catabolism of cytoplasmic and intramitochondrial adenine nucleotides in C2C12 skeletal myotube under chemical hypoxia.
Short-term intestinal ischemia-reperfusion alters intestinal motility that can be preserved by xanthine oxidase inhibition.
Aldehyde oxidoreductase activity in Desulfovibrio gigas: in vitro reconstitution of an electron-transfer chain from aldehydes to the production of molecular hydrogen.
Effects of bile acids on the muscle functions of guinea pig gallbladder.
Inhibitory effect of allopurinol on adjuvant arthritis in rats.
Native LDL and minimally oxidized LDL differentially regulate superoxide anion in vascular endothelium in situ.
The determination of allopurinol and oxipurinol in human plasma and urine.
15-Deoxy-delta12,14-prostaglandin J2 induces apoptosis of a thyroid papillary cancer cell line (CG3 cells) through increasing intracellular iron and oxidative stress.
Early treatment with allopurinol in familial juvenile hyerpuricaemic nephropathy (FJHN) ameliorates the long-term progression of renal disease.
Protective effect of allopurinol in the exposure to noise pulses
Effect of phorone and allopurinol on ischemia-reperfusion injury in gastrointestinal mucosa of the rat.
Use of antioxidants for the prophylaxis of cold-induced peripheral nerve injury.
Hydrochlorothiazide, allopurinol and magnesium oxide in the treatment of recurrent calcium urolithiasis
NADH-FMN oxidoreductase activity and iron content of organs from riboflavin and iron-deficient rats.
Pharmacological interventions in the newborn piglet in the first 24 h after hypoxia-ischemia. A hemodynamic and electrophysiological perspective.
On the specificity of allopurinol and oxypurinol as inhibitors of xanthine oxidase. A pulse radiolysis determination of rate constants for reaction of allopurinol and oxypurinol with hydroxyl radicals.
Allopurinol and superoxide dismutase protect against leucocyte-endothelium interactions in a novel model of colonic ischaemia-reperfusion.
Gene expression levels of cytokine profile and cytotoxic markers in non-immediate reactions to drugs.
Stretch enhances contraction of bovine coronary arteries via an NAD(P)H oxidase-mediated activation of the extracellular signal-regulated kinase mitogen-activated protein kinase cascade.
Heterogeneity of sucrose synthase genes in bean (Phaseolus vulgaris L.): evidence for a nodule-enhanced sucrose synthase gene.
Vitamin E blocks early events induced by 1-methyl-4-phenylpyridinium (MPP+) in cerebellar granule cells.
Clinical study of treatment on chronic uric acid nephropathy by integrating Western and traditional Chinese medicine
Endothelin-1 increases vascular superoxide via endothelin(A)-NADPH oxidase pathway in low-renin hypertension.
Effect of oxidants on small intestinal brush border membranes and colonic apical membranes--a comparative study.
Reperfusion arrhythmias: dose-related protection by anti-free radical interventions.
Pathophysiology, diagnosis and conservative therapy of non-calcium kidney calculi
Beneficial effects of allopurinol on glutathione levels and glutathione peroxidase activity in rat ischaemic acute renal failure.
Microencapsulation of allopurinol by solvent evaporation and controlled release investigation of drugs.
Evidence for oxidative stress in NSAID-induced colitis in IL10-/- mice.
Zonal distribution of allopurinol-oxidizing enzymes in rat liver.
Molecular cloning of the cDNA encoding aspartate aminotransferase from bean root nodules and determination of its role in nodule nitrogen metabolism.
The effect of allopurinol on cyclophosphamide antitumor activity.
Chronic administration of allopurinol fails to exert any cardioprotective effect in rats submitted to permanent coronary artery ligation.
Repetitive brief ischemia: intermittent reperfusion during ischemia ameliorates the extent of injury in the perfused kidney.
The protective effects of allopurinol and superoxide dismutase-polyethylene glycol on ischemic and reperfusion-induced cochlear damage.
Ethanol potentiates doxorubicin-induced inhibition of cell survival in cultured Chinese hamster ovary cells.
Induced expression of manganese superoxide dismutase by non-toxic concentrations of oxidized low-density lipoprotein (oxLDL) protects against oxLDL-mediated cytotoxicity.
Chemical diagnosis of Lesch-Nyhan syndrome using gas chromatography-mass spectrometry detection.
In vivo administration of allopurinol affects ovulation and early embryonic development in rabbits.
Non-invasive analysis of reactive oxygen species generated in NH4OH-induced gastric lesions of rats using a 300 MHz in vivo ESR technique.
Cutaneous reactions in hairy cell leukaemia treated with 2-chlorodeoxyadenosine and allopurinol.
Xanthine oxidase and activated neutrophils cause oxidative damage to skeletal muscle after contractile claudication.
Measurement of free radical generation from endothelial cells and observation of cell injury exposed to anoxia-reoxygenation
Twenty-four-hour hypothermic preservation of rat liver with Euro-Collins and UW solutions. A comparative evaluation by 31P NMR spectroscopy, biochemical assays, and light microscopy.
Allopurinol inhibits CXC chemokine expression and leukocyte adhesion in endotoxemic liver injury.
Preventive effects of oren-gedoku-to on mucositis caused by anticancer agents in patients with acute leukemia
The role of allopurinol and deferoxamine in preventing pressure ulcers in pigs.
Mutational analysis of the xanthine dehydrogenase gene in a Turkish family with autosomal recessive classical xanthinuria.
Heme precursor 5-aminolevulinic acid alters brain tryptophan and serotonin levels without changing pineal serotonin and melatonin concentrations.
Effects of the anti-ICAM-1 monoclonal antibody, allopurinol, and methylene blue on intestinal reperfusion injury.
The use of allopurinol in the inhibition of obliterative bronchiolitis of the transplanted lung.
Development of a capillary electrophoresis method for the determination of allopurinol and its active metabolite oxypurinol.
Outcome of metabolic evaluation and medical treatment for calcium nephrolithiasis in a private urological practice.
Oxidized low-density lipoprotein autoantibodies in patients with primary gout: effect of urate-lowering therapy.
Xanthine oxidoreductase and cardiovascular disease - molecular mechanisms and pathophysiologic implications.
Tandem orientation of duplicated xanthine dehydrogenase genes from Arabidopsis thaliana: differential gene expression and enzyme activities.
Reactive oxygen and nitrogen intermediates contribute to Haemophilus somnus lipooligosaccharide-mediated apoptosis of bovine endothelial cells.
Demonstration of a combined deficiency of xanthine oxidase and aldehyde oxidase in xanthinuric patients not forming oxipurinol.
Lung injury and complement activation: role of neutrophils and xanthine oxidase.
Removing oxygen-derived free radicals delays hepatic metastases and prolongs survival in colonic cancer. A study in the rat.
The inhibitory effects of allopurinol on the production and cytotoxicity of tumor necrosis factor.
Effect of allopurinol on the survival of experimental pig flaps.
Ischemia-reperfusion induced gastric mucosal microcirculatory alterations in the rat.
Purpurogallin--a natural and effective hepatoprotector in vitro and in vivo.
Mechanisms of the effect of allopurinol on the metabolism of adenine nucleotides
The misdiagnosis of gout and hyperuricemia.
Factors influencing survival of mammalian cells exposed to hypothermia. V. Effects of hepes, free radicals, and H2O2 under light and dark conditions.
Differential pathophysiology of bacterial translocation after thermal injury and sepsis.
Role of xanthine oxidase and neutrophils in ischemia-reperfusion injury in rabbit lung.
Effect of anti-inflammatory drugs on xanthine oxidase and xanthine oxidase induced depolymerization of hyaluronic acid.
Dependence on O2- generation by xanthine oxidase of pathogenesis of influenza virus infection in mice.
Two new potent inhibitors of xanthine oxidase from leaves of Perilla frutescens Britton var. acuta Kudo.
Removing oxygen-derived free radicals stimulates healing of ethanol-induced erosive gastritis in the rat.
Histamine release and SOD, allopurinol and ranitidine pretreatment in haemorrhagic shock in the rat.
Alcohol, iron and oxidative stress
Phase I study of tiazofurin (2-beta-D-ribofuranosylthiazole-4-carboxamide, NSC 286193).
Influence of hypoxanthine, allopurinol and adenine on resistance of rats and hamsters to hypobaric hypoxia.
Phase II study of cisplatin, 5-FU, and allopurinol in advanced esophageal cancer.
Radical production during in vivo intestinal ischemia and reperfusion in the cat.
Allopurinol use and the risk of cataract formation.
A new and quick method for determination of allopurinol and oxipurinol in serum
Role of xanthine oxidase in the genesis of acute pancreatitis
Inhibition of infectivity of human immunodeficiency virus by a novel nucleoside, oxetanocin, and related compounds.
Protection of rat myocardial phospholipid against peroxidative injury through superoxide-(xanthine oxidase)-dependent, iron-promoted Fenton chemistry by the male contraceptive gossypol.
Intravesical high dose 5-fluorouracil instillations combined with allopurinol--a therapeutic alternative in the treatment of multiple bladder tumors.
Oxygen-derived free radicals promote hepatic injury in the rat.
The influence of symptoms of disease and side effects of treatment on compliance with cancer therapy.
Selective cytotoxicity of an oxygen-radical-generating enzyme conjugated to a monoclonal antibody.
Anti-leishmanial effect of allopurinol ribonucleoside and the related compounds, allopurinol, thiopurinol, thiopurinol ribonucleoside, and of formycin B, sinefungin and the lepidine WR6026.
Allopurinol does not enhance antioxidant properties of extracellular fluid.
Renal capillary permeability and intravascular red cell aggregation after ischaemia. I. Effects of xanthine oxidase activity.
Microsomal nitroreductase activity of rabbit kidney and bladder: implications in 5-nitrofuran-induced toxicity.
NAD(P)+-independent aldehyde dehydrogenase from Pseudomonas testosteroni. A novel type of molybdenum-containing hydroxylase.
Enhancement of hypoxic liver damage by ethanol. Involvement of xanthine oxidase and the role of glycolysis.
Differential metabolism of allopurinol and derivatives in Trypanosoma rangeli and T. cruzi culture forms.
Allopurinol in renal failure and the tumour lysis syndrome.
Effect of mannitol, dextran (macrodex), allopurinol, and methylprednisolone on the morphology of the proximal tubule of the rat kidney made ischemic in vivo.
Effect of deferoxamine and allopurinol on non-protein-bound iron concentrations in plasma and cortical brain tissue of newborn lambs following hypoxia-ischemia.
Oxidant injury to the alveolar epithelium: biochemical and pharmacologic studies.
On the dose-effect relation of allopurinol
Effects of superoxide anions on the (Na + K)ATPase system in rat lung.
Pharmaco-dynamic mechanisms for reducing the activity of an epileptogenic focus with allopurinol
Risk factors for adverse drug reactions communication of the CHDM.
Allopurinol in the treatment of visceral leishmaniasis.
Effect of allopurinol on the survival of hyperemic island skin flaps.
Effect of allopurinol on the pharmacokinetics of 6-mercaptopurine in rabbits.
Biological action of inosine analogs in Leishmania and Trypanosoma spp.
Stability of allopurinol and of five antineoplastics in suspension.
Reduction in urinary oxalate values by allopurinol.
Quantification of renal uric acid synthesis in the rat.
Metabolism of 6-thiopurines. II. Covalent binding of a 6-thiopurine metabolite to mammalian tissue protein in vivo.
Quantitative in situ analysis of xanthine oxidoreductase activity in rat liver.
The real and apparent plasma oxalate.
Effect of antirheumatic drugs on cathepsin B1 from bovine spleen.
Release of hydrogen peroxide in response to hypoxia-reoxygenation: role of an NAD(P)H oxidase-like enzyme in endothelial cell plasma membrane.
The effect of allopurinol on urinary oxalate excretion in stone formers.
Involvement of free radicals in MPP+ neurotoxicity against rat dopaminergic neurons in culture.
Modifications to the rate of wound contraction by allopurinol.
Stevens-Johnson syndrome and toxic epidermal necrolysis in Thailand.
Chemiluminescent measurement of increased free radical formation after ischemia/reperfusion. Mechanisms of free radical formation in the liver.
Effects of allopurinol on in vivo suppression of arthritis in mice and ex vivo modulation of phagocytic production of oxygen radicals in whole human blood.
The effect of allopurinol on the liver ultrastructure, reduced glutathione and lipid peroxide levels during liver ischemia in guinea pigs.
A quantitative histochemical study of xanthine oxidase activity in rat liver using the cerium capture method in the presence of polyvinyl alcohol.
Effect of allopurinol on the concentration of endogenous glutathione in hepatocytes after an hour of normothermic liver ischemia.
Myocardial protection during ischemic cardiac arrest. Hemodynamic study of the effects of allopurinol in a cardioplegic solution
Role of xanthine oxidase and reactive oxygen intermediates in LPS- and TNF-induced pulmonary edema.
Role of superoxide dismutase in mechanism of diethyldithiocarbamate-induced gastric antral ulcer in rats: protective effect of prostaglandin, cimetidine and pirenzepine.
Role of oxygen-derived free radicals in stress-induced gastric ulceration
Effect of leukocyte adhesion and microvascular permeability on capillary perfusion during ischemia-reperfusion injury in hamster cheek pouch.
Arterial endothelial barrier dysfunction: actions of homocysteine and the hypoxanthine-xanthine oxidase free radical generating system.
How are urine composition and stone disease affected by therapeutic measures at an outpatient stone clinic?
The effect of allopurinol on interstitial purine metabolism and tissue damage in skeletal muscle I-R injury.
Ischemia-reperfusion-induced muscle damage. Protective effect of corticosteroids and antioxidants in rabbits.
Allopurinol in the treatment of zoonotic cutaneous leishmaniasis.
The role of hyperuricemia in the increased cytokine production after lipopolysaccharide challenge in neutropenic mice.
Early midzonal cell death during low-flow hypoxia in the isolated, perfused rat liver: protection by allopurinol.
Effects of time and dilution on concentration of xanthine in frozen urine and plasma of dogs.
Acceleration of hypertensive cerebral injury by the inhibition of xanthine-xanthine oxidase system in stroke-prone spontaneously hypertensive rats.
Role of free radicals in the mechanism of the hydrazine-induced formation of megamitochondria.
Cocaine-induced liver injury in mice is mediated by nitric oxide and reactive oxygen species.
An isocratic, reversed-phase HPLC method for the determination of postischemic efflux of purines and pyrimidines during reperfusion of isolated liver.
Involvement of free radicals and histamine in the potentiating action of cigarette smoke exposure on ethanol-induced gastric mucosal damage in rats.
Pharmacokinetic and clinical studies of a new uricosuric agent - benzbromarone.
The role of xanthine oxidase in platelet activating factor induced intestinal injury in the rat.
Secondary treatment of polycythemia rubra vera with 6-thioguanine.
Evaluating the antioxidant potential of new treatments for inflammatory bowel disease using a rat model of colitis.
Xylazine-induced pulmonary edema in rats.
Allopurinol-enhanced postischemic recovery in the isolated rat heart involves repletion of high-energy phosphates.
Xanthine oxidase potentiation of reactive oxygen intermediates in isolated canine peripheral neutrophils.
Reactive oxygen metabolites produce pulmonary vasoconstriction in young pigs.
Role of xanthine oxidase in postischemic microvascular injury in skeletal muscle.
Lymphocyte transformation and radioallergosorbent tests in drug hypersensitivity.
Requirements for neutrophil products and L-arginine in ischemia-reperfusion injury.
Platelet-activating factor (PAF) up-regulates plasma and tissue PAF-acetylhydrolase activity in the rat: effect of cycloheximide.
Allopurinol, indomethacin and riboflavin enhance radiation lethality in mice.
A survey of current prescribing practices of antiinflammatory and urate-lowering drugs in gouty arthritis.
Modification of ischemia and reperfusion damage of skeletal muscles with allopurinol: in vivo 31P MR spectroscopy of the posterior limb of the rat
Evaluation of the effectiveness of 5'-nucleotidase inhibitor and allopurinol in myocardial ischemia.
Induction of nitric oxide and nitric oxide synthase mRNA by silica and lipopolysaccharide in PMA-primed THP-1 cells.
Effect of 24-hour preservation with oxygen free radical scavengers on isolated-perfused canine heart-lungs.
Kidney protection by pretreatment with free radical scavengers and allopurinol: renal function at recirculation after warm ischaemia in rabbits.
Protective influence of pretreatment with allopurinol on myocardial function in patients undergoing coronary artery surgery.
Allopurinol in the prevention of calcium oxalate renal stones. Preliminary results.
Free radical scavengers prevent reflux esophagitis in rats.
Increases of cell ATP produced by exogenous adenine nucleotides in isolated rabbit kidney tubules.
The role of superoxide anions in the establishment of an interferon-alpha-mediated antiviral state.
Experimental analysis of progressive necrosis after spinal cord trauma in the rat: etiological role of the inflammatory response.
Leishmania infantum promastigotes: flow cytometry as a possible tool for assessing the effects of drugs on cellular functions.
Excellent uricosuric efficacy of benzbromarone in cyclosporin-A-treated renal transplant patients: a prospective study.
An endothelium-dependent contraction in canine mesenteric artery caused by caffeine.
Chemical and spectral properties of carbon monoxide: methylene blue oxidoreductase. The molybdenum-containing iron-sulfur flavoprotein from Pseudomonas carboxydovorans.
The prevalence and prophylaxis of gout in England.
Failure of allopurinol to protect against cerebral injury when given after the start of hypoxia.
Dibutyryl cAMP, prostaglandin E2, and antioxidants protect cultured bovine bronchial epithelial cells from endotoxin.
Purine metabolism in the protozoan parasite Eimeria tenella.
Cardioprotective effect of propranolol from alcohol-induced heart muscle damage as assessed by plasma cardiac troponin-t.
The role of allopurinol in preventing oxygen free radical injury to skeletal muscle and endothelial cells after ischemia-reperfusion.
Oxidation of selected pteridine derivatives by mamalian liver xanthine oxidase and aldehyde oxidase.
Oxygen radicals induce pulmonary vasoconstriction in pigs without activating plasma proteolytic cascade systems.
Biochemical studies on the purine metabolism of four cases with hereditary xanthinuria.
Hormonal and metabolic adaptation to protein-supplemented fasting in obese subjects.
Studies on purine-pyrimidine metabolism (1)--Quantitation of purine-pyrimidine metabolites and allopurinol-oxipurinol in biological fluids
The influence of dietary purines and pyrimidines on purine and pyrimidine biosynthesis in man.
Immunology of pyelonephritis. VII. Effect of allopurinol.
In vitro oxidation of pyrazinamide and allopurinol by rat liver aldehyde oxidase.
Mechanisms of action of pyrazolopyrimidines in Leishmania donovani.
The synergistic action of pyrazolopyrimidines and pentavalent antimony against Leishmania donovani and L. braziliensis.
Prevention of free radical-induced myocardial injury by allopurinol. Experimental study in cardiac preservation and transplantation.
Effect of oxygen free radicals and lipid peroxides on cardiac isoenzymes.
Effect of oxygen free radicals on rabbit and human erythrocytes. Studies on cellular deformability.
Effects of oxygen free radical scavengers, xanthine oxidase inhibition and calcium entry-blockers on leakage of albumin after ischaemia. An experimental study in rabbit kidneys.
A comparative study on the effect of various pharmacological agents on the survival of skin flaps in the rat.
Metabolism of pyrazinamide and allopurinol in hereditary xanthine oxidase deficiency.
The role of oxygen free radicals in mediating the reperfusion injury of cold-preserved ischemic kidneys.
Generation of adriamycin radical by interaction of adriamycin with serum.
The effects of allopurinol and superoxide dismutase in a rat model of skin flap necrosis.
Evidence for an early free radical-mediated reperfusion injury in frostbite.
Nucleotide degradation and radical formation in ischemic and reperfused small intestine.
Xanthine oxidase-derived reactive oxygen species activate nuclear factor kappa B during hepatic ischemia in rats.
Cutaneous adverse drug reactions in a hospital setting.
Human fibroblasts release reactive oxygen species in response to interleukin-1 or tumour necrosis factor-alpha.
Superoxide dismutase recovers altered endothelium-dependent relaxation in diabetic rat aorta.
Allopurinol can act as an electron transfer agent. Is this relevant during reperfusion injury?
Is selective therapy of recurrent nephrolithiasis possible?
The role of specific reductases in the intracellular activation and binding of 2-nitroimidazoles.
The effects of allopurinol and clofibrate on the elimination of coumarin anticoagulants in man.
Effect of oxypurinol on renal reperfusion injury in the rat.
Recurrence after a single renal stone in a community practice.
Hypoxia reoxygenation-induced injury of cultured pulmonary microvessel endothelial cells.
Role of leukocytes in reperfusion injury of skeletal muscle after partial ischemia.
Allopurinol and reperfusion-induced arrhythmias: increased protection by simultaneous administration of anti-oxidant enzymes.
Differences in allopurinol and 4-aminopyrazolo(3,4-d) pyrimidine metabolism in drug-sensitive and insensitive strains of Trypanosoma cruzi.
Improved survival in a replantation model containing ischemic muscle.
Effect of some dietary additions to either an arginine-devoid diet or a diet supplemented with orotic acid refed after starvation on liver lipid content during essential fatty acid deficiency in rats.
Effect of isoproterenol on renal uric acid excretion in rats.
Adverse drug reaction reporting in the Singapore General Hospital.
Oxygen free radicals are required for ischemia-induced leukotriene B4 synthesis and diapedesis.
Allopurinol plus standard resuscitation preserves hepatic blood flow and function following hemorrhagic shock.
Xanthine oxidase is not responsible for reoxygenation injury in isolated-perfused rat heart.
Allopurinol treatment results in elevated prostate-specific antigen levels in prostatic fluid and serum of patients with non-bacterial prostatitis.
The effect of allopurinol ribonucleoside and formycin B on Trypanosoma cruzi infections in mice.
Plasma xanthine oxidase and resistance to hypoxia: effect of purines and alcohol administration.
Role of oxygen-derived free radicals in the pathogenesis of gastric mucosal lesions in rats.
Role of oxygen-derived free radicals in the mechanism of chronic gastric ulceration in the rat: implications for cytoprotection.
Protective agents used as additives in University of Wisconsin solution to promote protection against ischaemia-reperfusion injury in rat lung.
Molecular characterization and overexpression of the hypoxanthine-guanine phosphoribosyltransferase gene from Trypanosoma cruzi.
Role of oxygen derived free radicals in platelet activating factor induced bowel necrosis.
"Pouchitis": new routes of research and signification
Active drug metabolites and renal failure.
Role of oxygen-derived free radicals in protease activation after pancreas transplantation in the pig.
Influence of free radical scavengers on myeloperoxidase activity and lipid peroxidation in acute skin grafts.
Uric acid as radical scavenger and antioxidant in the heart.
Effect of free-radical scavengers and hyperbaric oxygen on random-pattern skin flaps.
The role of Ca(2+)-ATPase and oxygen radical in reperfusion injury of rat liver
Leishmania mexicana: drug sensitivities of promastigotes and transforming amastigotes.
Xanthine oxidase and endothelium dependent relaxation.
Impairment of grafts by short-term warm ischemia in rat liver transplantation.
A comparison of some simplified lactobionate preservation solutions with standard UW solution and Eurocollins solution for pancreas preservation.
Potentiation of ampicillin skin reactions by allopurinol or hyperuricemia.
Effects of allopurinol on smoke inhalation in the ovine model.
Metabolic activation of 2- and 3-nitrodibenzopyranone isomers and related compounds by rat liver S9 and the effect of S9 on the mutational specificity of nitrodibenzopyranones.
Hyperuricemia induced by some antihypertensives and uricosuric drugs in oxonate-treated rats.
Xanthine oxidase is not a source of free radicals in the ischemic rabbit heart.
Rapid reactive oxygen species production by mitochondria in endothelial cells exposed to tumor necrosis factor-alpha is mediated by ceramide.
Effect of reactive oxygen species on the biosynthesis and structure of newly synthesized proteoglycans.
Effect of anthracycline antibiotics on oxygen radical formation in rat heart.
Glycolytic support of adenine nucleotides in rat liver flush-preserved with UW or Collins' II. Importance of donor nutritional status.
Pathophysiology of ischemic skin flaps: differences in xanthine oxidase levels among rats, pigs, and humans.
Effects of the free radical scavenger DMTU and mannitol on the oxygen paradox in perfused rat hearts.
Enhancement of the antidepressant response to L-tryptophan by a liver pyrrolase inhibitor: a rational treatment approach.
Oxygen-derived free radical scavengers: a new approach to the problem of refractory peptic ulceration.
Erythrocyte membrane stabilization by calcium channel blockers, calmodulin antagonists and scavengers of oxygen free radicals.
Monosodium urate crystals stimulate phospholipase A2 enzyme activities and the synthesis of a phospholipase A2-activating protein.
Urate and calcium stones--picking up a drop of mercury with one's fingers?
Conservative treatment of staghorn and residual calculi
Early midzonal oxidative stress preceding cell death in hypoperfused rat liver.
Prevention of oxidative stress due to tourniquet application. Analysis of the effects of local hypothermia and systemic allopurinol administration.
Mechanisms of endotoxin-induced intestinal injury in a hyperdynamic model of sepsis.
Ethanol-induced oxidative stress in the rat cerebellum.
Comparative in vitro studies of allopurinol in commercial preparations
Factors determining successful liver preservation for transplantation.
Hepatic catalase and superoxide dismutases after acute ethanol administration in rats.
IL-10 deficiency increases superoxide and endothelial dysfunction during inflammation.
Time-dependent changes in superoxide dismutase, catalase, xanthine dehydrogenase and oxidase activities in focal cerebral ischaemia.
Brief hypoxic stress suppresses postbacteremic NF-kappaB activation and TNF-alpha bioactivity in perfused liver.
Complex cases in heart surgery
5-fluorocytosine susceptibility of pathogenic fungi in the presence of allopurinol: potential for improving the therapeutic index of 5-fluorocytosine.
Lack of effect of antioxidant therapy during renal ischemia and reperfusion in dogs.
Effects of allopurinol on endotoxin-induced increase in serum xanthine oxidase in the horse.
Inhibition of nitric oxide synthase by a superoxide generating system.
Local skin burn causes systemic (lung and kidney) endothelial cell injury reflected by increased circulating and decreased tissue factor VIII-related antigen.
Antileishmanial drug targeting through glycosylated polymers specifically internalized by macrophage membrane lectins.
Tumor necrosis factor is a terminal mediator in galactosamine/endotoxin-induced hepatitis in mice.
Secondary metabolism of theophylline biotransformation products in man--route of formation of 1-methyluric acid.
Effect of allopurinol on the indicators of immunity in podagra and experimental hyperuricemia
Compliance with oral drug therapy in patients with hematologic malignancy.
Application of various antioxidants in the treatment of influenza.
Inhibition by SKF-525A of the aldehyde oxidase-mediated metabolism of the experimental antitumour agent acridine carboxamide.
Does benzbromarone in therapeutic doses raise renal excretion of oxipurinol?
Adhesion molecule mediated endothelial cell injury elicited by activated leukocytes.
Histamine release in acute coronary occlusion-reperfusion in isolated guinea-pig heart.
Biochemically directed therapy of leukemia with tiazofurin, a selective blocker of inosine 5'-phosphate dehydrogenase activity.
Oral anticoagulation therapy in the primary care setting
Effect of antioxidative therapy on regeneration of ischemic liver
Superoxide dismutases and anti-oxidants protected mice from no-reflow and necrotic damage induced by ischemia.
The anti-inflammatory and anti-hyperuricemic effects of Chinese herbal formula danggui-nian-tong-tang on acute gouty arthritis: a comparative study with indomethacin and allopurinol.
Infarct size limitation by the xanthine oxidase inhibitor, allopurinol, in closed-chest dogs with small infarcts.
Summation and synergism in the promotion of urinary bladder carcinogenesis initiated by N-butyl-N-(4-hydroxybutyl)-nitrosamine in F344 rats.
The role of neutrophils in the production of hypoxic-ischemic brain injury in the neonatal rat.
Protective effects of tirilazad mesylate in a cellular model of peroxynitrite toxicity.
Reactive oxidants mediate TNF-alpha-induced leukocyte adhesion to rat mesenteric venular endothelium.
The effect of flavins and enzyme inhibitors on 4-nitrobenzoic acid reductase and azo reductase of Ascaris lumbricoides var suum.
Hypersensitivity reaction to allopurinol
Vanadate-induced toxicity towards isolated perfused rat livers: the role of lipid peroxidation.
Combination allopurinol and antimony treatment versus antimony alone and allopurinol alone in the treatment of canine leishmaniasis (96 cases).
Effect of hyperbaric oxygen treatment and perfluorochemical administration on glutathione status of the lung.
The role of acetaldehyde in the pathogenesis of acute alcoholic pancreatitis.
Endotoxin-induced bacterial translocation: a study of mechanisms.
Allopurinol amelioration of the pathophysiology of acute myocardial infarction in rats.
Role of aldehyde oxidase in the in vitro conversion of famciclovir to penciclovir in human liver.
Elucidation of pathways of 5-fluorouracil metabolism in xenografts of human colorectal adenocarcinoma.
Hypouricaemia
Plasmapheresis in toxic epidermal necrolysis.
Autosomal dominant transmission of gouty arthritis with renal disease in a large Japanese family.
Mechanism of erythrocyte trapping in ischaemic acute renal failure.
Plasma exchange (PE) treatment in drug-induced toxic epidermal necrolysis (TEN).
Comparison of the effect of a mitochondrial uncoupler, 2,4-dinitrophenol and adrenaline on oxygen radical production in the isolated perfused rat liver.
Evidence that free radicals are involved in graft failure following orthotopic liver transplantation in the rat--an electron paramagnetic resonance spin trapping study.
N2-methyl-8-oxoguanine: a tRNA urinary metabolite--role of xanthine oxidase.
Purine base uptake in Trypanosoma cruzi: adaptations and effects of inhibitors.
The role of free serum tryptophan in the biphasic effect of acute ethanol administration on the concentrations of rat brain tryptophan, 5-hydroxytryptamine and 5-hydroxyindol-3-ylacetic acid.
Acute gastric stress ulceration: prophylaxis with allopurinol.
Purine metabolism in normal and ITP-pyrophosphohydrolase-deficient human erythrocytes.
Observations and effects of educational consults on allopurinol prescribing.
Comparative accumulation of uric acid and hypoxanthine by slices of avian renal cortex.
Effect of nutritional state and allopurinol on purine metabolism in the rat small intestine.
Effects of allopurinol on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurochemical changes in the striatum and in the brainstem of the rat.
Conservative treatment of urolithiasis in children
Xanthine oxidase inhibitors attenuate ischemia-induced vascular permeability changes in the cat intestine.
A possible mechanism for vascular endothelial cell injury elicited by activated leukocytes: a significant involvement of adhesion molecules, CD11/CD18, and ICAM-1.
Procyanidines from Vitis vinifera seeds protect rabbit heart from ischemia/reperfusion injury: antioxidant intervention and/or iron and copper sequestering ability.
Use of rat and human in vitro systems to assess the effectiveness and enzymology of deoxy-guanine analogues as prodrugs of an antiviral agent.
Purpurogallin protects both ventricular myocytes and aortic endothelial cells of rats against oxyradical damage.
Interaction of allopurinol with phenprocoumon in man.
Possible involvement of the enhanced tryptophan pyrrolase activity in the corticosterone- and starvation-induced increases in concentrations of nicotinamide-adenine dinucleotides (phosphates) in rat liver.
Treatment of two patients with diffuse cutaneous leishmaniasis caused by Leishmania mexicana modifies the immunohistological profile but not the disease outcome.
Myelosuppression associated with azathioprine-allopurinol interaction after heart and lung transplantation.
New guaianolides and xanthine oxidase inhibitory flavonols from ajania fruticulosa
Cerebral uric acid, xanthine, and hypoxanthine after ischemia: the effect of allopurinol.
Involvement of the xanthine-xanthine oxidase system and neutrophils in the development of acute gastric mucosal lesions in rats with water immersion restraint stress.
The presence of desulfo xanthine dehydrogenase in purified and crude enzyme preparations from rat liver.
Rapid conversion to high xanthine oxidase activity in viable Kupffer cells during hypoxia.
Subcellular distribution of xanthine oxidase during cardiac ischemia and reperfusion: an immunocytochemical study.
Effect of allopurinol (zyloric) on patients undergoing open heart surgery.
Causes of the preferential action of imuran on the viability and proliferative activity of a Chinese hamster cell culture in the stationary growth phase
Effect of glucagon on renal excretion of oxypurinol and purine bases.
Free radical scavenging and antioxidant activity of allopurinol and oxypurinol in experimental lens-induced uveitis.
Non-enzymatic and enzymatic activation of mitomycin C: identification of a unique cytosolic activity.
Hypoxanthine uptake through a purine-selective nucleobase transporter in Trypanosoma brucei brucei procyclic cells is driven by protonmotive force.
Veratridine induces apoptotic death in bovine chromaffin cells through superoxide production.
Allopurinol and oxypurinol are hydroxyl radical scavengers.
Action of allopurinol and aspirin on rat whole-embryo cultures.
Determination of 6-thioguanine and 6-methylmercaptopurine metabolites in renal transplantation recipients and patients with glomerulonephritis treated with