References: Hair growth and hair loss
Ann Plast Surg. 1995 Aug;35(2):154-8.
Animal study of skin resurfacing using the ultrapulse carbon dioxide laser.
Yang CC, Chai CY.
Department of Surgery, Kaohsiung Medical College Hospital, Taiwan.
Ultrapulse carbon dioxide laser ablation of rabbit skin was investigated. Macroscopic and microscopic appearance of the ablation site was evaluated for 1 month. The Ultrapulse carbon dioxide laser was set in the ultrapulse mode and the parameters selected were 250 mJ of energy per pulse and 2 W average power with the 3-mm spot size collimated handpiece. Macroscopic investigation showed that ultrapulse carbon dioxide laser ablation removed rabbit skin precisely and bloodlessly without char formation. Skin re-epithelialization without scarring and perfect hair growth restoration within 3 weeks were impressive. Microscopic investigation demonstrated a layer of tissue thermal necrosis measured as 70 +/- 10 microns. During the first 2 weeks, laser ablation wound re-epithelialization begins with multiplying epidermal layers (from 2-3 cell layers to about 13 to 15 cell layers). There were marked fibroblastic reactions and capillary congestion within papillary dermis. By the end of 4 weeks, the thickened epidermal layer appeared normal. The repaired papillary dermal collagen showed a relative compact configuration and greater cellularity in Masson stain was found 2 to 3 weeks later and also was near normal 4 weeks after laser treatment. These findings suggest that Ultrapulse's delivery of short-duration, high-energy pulses may provide a new approach (laser dermal ablation) to damage selectively the epidermis and papillary dermis of rabbit skin in one single-pulse impaction with uneventful wound healing within 1 month.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=7486737&dopt=Abstract
Dermatol Surg. 1995 Nov;21(11):963-9.
A concentric method for mini-micrografting extensively bald patients.
Brandy DA.
Department of Dermatology, University of Pittsburgh Medical Center, Pennsylvania 15220, USA.
BACKGROUND. A concentric method for mini-micrografting extensively bald patients is described. OBJECTIVE. To demonstrate a method that effectively treats those extensively bald patients who wish to forgo any type of alopecia-reducing procedure posteriorly. METHOD. Initially the hairline is developed. Then the remaining posterior area of alopecia is gradually infringed upon in a concentric fashion. RESULTS. Excellent results are accomplished with this method and, most importantly, the patient looks normal at any point during the treatments. If donor hair becomes depleted or the patient wishes no further treatments, he/she is left with a normal appearance. CONCLUSION. The method of performing mini-micrografts, starting from the front and moving posteriorly in a progressively concentric fashion, creates a very natural result at almost all phases of the surgical hair restoration.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=7582835&dopt=Abstract
Dermatol Surg. 1995 Apr;21(4):306-11.
Micrografting in extensive quantities. The ideal hair restoration procedure.
Rassman WR, Carson S.
BACKGROUND. Smaller hair transplant grafts in greater quantities are becoming an unmistakable trend. As hair grow in groups of one to four, the process is mathematically and aesthetically logical. OBJECTIVE. To produce a natural appearing distribution of hair in the balding individual in an acceptable time frame. METHODS. Grafts reflecting natural patterns are used. Four hundred one-hair grafts are densely packed into a frontal hairline 4-5 mm wide to create a transition zone between the forehead and a new hairline. Two- to four-hair grafts are densely packed behind the frontal zone in a graded fashion. Grafts containing no more than four hairs are used. RESULTS. The results produce a slightly less dense but better balance that looks like the natural veneer of a normal mature male. In women or men with thinning hair, surgically increasing density satisfies many patient objectives. CONCLUSION. Transplantation with one- to four-hair grafts in extensive quantities produces a natural "hairy" appearance without the artificial look typical of the large traditional grafts. By using this technique, many patients can be completed in just one session.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=7728480&dopt=Abstract
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