References: Hair growth and hair loss
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The eyebrow has a powerful influence on the appearance of the orbital region. Because the person without eyebrows has an unnatural look, drawing everyone's attention, eyebrow restoration/reconstruction should be viewed as an esthetic surgery performed to improve the patient's appearance and self-esteem. Although hair-bearing pedicled flaps and free composite strip grafts have been the most widely used approaches in clinical practice formerly, follicular unit transplantation (FUT) has gained more and more importance nowadays in eyebrow restoration because of its more rewarding results. The process and results of FUT have been greatly improved thanks to advances in hair transplantation techniques, instrumentation, and practice. In this article, we discuss the restoration of 14 eyebrows in 8 patients (5 males and 3 females) using FUT. The procedure and the results also are discussed here under in light of literature.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14646654&dopt=Abstract [PubMed - in process]
Ann Plast Surg. 2003 Dec;51(6):627-9.
Long-term follow-up and unusual findings after microvascular transfer of hair-bearing skin for pubic hair restoration.
Chen HC, Mardini S, Santamaria E.
Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, 9 Alley 23, Lane 76, Ho-Ping East Road, Taipei, Taiwan.
Alopecia in the pubic area can be restored successfully with hair transplantation using minigrafts and micrografts or with free tissue transfer of a hair bearing flap. In this report the authors present the successful transfer of hair bearing tissue from the temporoparietal scalp for the correction of a congenital form of alopecia of the pubic region. In addition, they present long term results of this transfer. Auxiliary procedures such as tissue expansion before or after transferring the flap, hair epilation and minigraft and micrograft transplantation could help to achieve a more natural result. Tissue expansion of the donor site could also be performed to enhance the outcome of the procedure. Of note is the rapid rate of hair growth in the transplanted tissue. This type of reconstruction using a hair bearing temporoparietal flap for restoration of hair to the pubic region is a useful method that can yield good results.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14646664&dopt=Abstract [PubMed - in process]
Zhonghua Er Bi Yan Hou Ke Za Zhi. 1997 Jun;32(3):153-6.
[Regeneration and functional restoration of vestibular hair cells in guinea pigs after gentamicin damage]
[Article in Chinese]
Wang D, Wang Z.
Eye Ear Nose and Throat Hospital, Shanghai Medical University.
To investigate the possibility of regeneration and functional restoration of vestibular hair cells after toxic destruction, gentamicin (150 mg/kg per day) was given to guinea pigs subcutaneously for 10 days to induce damage of vestibular hair cells. The control animals received the same volume of saline. At 2, 4, 12 and 24 weeks after the treatment, animals were sacrificed and their vestibular organs prepared for scanning electronic microscopic study. Change of the hair cell density was studied using quantitative analysis techniques. Electronystagmogram, induced with ice water, was taken before and at 2, 4, 12, and 24 weeks after the treatment. Immature stereocillia bundles were noticed in regions with heavy hair cell loss in the utricle and crista ampullaris 2 weeks after treatment and were still visible 24 weeks after the treatment. Hair cell density (number of hair cells/100 microns basilar membrane length) decreased significantly at 12 weeks after treatment as compared with the control (P < 0.01), and showed partial recovery at 24 weeks after treatment as compared with 12 weeks after treatment (P < 0.05) which was still below normall level (P < 0.05). Vmean showed significant reduction at 4 and 12 weeks after treatment (P < 0.01), and recovery at 24 weeks (P < 0.05), which was still below the normal level (P < 0.01). SEM results indicated the potential of repair of vestibular hair cells in guinea pigs after damage which may occur 24 weeks after the damage. Quantitative analysis of hair cell density further suggests that regeneration is the mechanism of repair. The regenerated hair cells seen in this study may play a role in the restoration of vestibular function.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10743154&dopt=Abstract
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