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References: Hair growth and hair loss

Otolaryngol Head Neck Surg. 1988 Jun;98(6):607-11.
Hair cell loss and regeneration after exposure to intense sound in neonatal chicks.

Henry WJ, Makaretz M, Saunders JC, Schneider ME, Vrettakos P.

Department of Otorhinolaryngology and Human Communication, University of Pennsylvania, Philadelphia.

Neonatal chicks (between 1 and 3 days of age) were exposed to an intense pure tone for 48 hours, then killed immediately after removal from the sound, or 14 days later. Nonexposed age-matched animals served as controls. The inner ear was removed and the auditory receptor organ (the basilar papilla) was prepared for evaluation by scanning electron microscopy. The site of injury on the papilla was described in terms of hair-cell loss and location. The ears with no recovery showed a discrete lesion area, within which there was complete disruption of the hair-cell field and a 35% loss in hair cells. After 14 days' recovery, no hair cell loss could be detected, though the lesion could still be recognized by the disorganization of hair cells in the previously injured area. These data demonstrate hair-cell restoration after severe acoustic injury from intense sound exposure in the neonatal ear.

online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3138621&dopt=Abstract

erols.com

Hair on a man's head is an important emblem of health, youth, and vitality. As in all areas of cosmetic surgery, the refinements of surgical technique and instrumentation have improved the results of hair transplantation. The state of the art in hair grafting today produces a result that is undetectable as being a surgical hair transplant. Many earlier techniques of plug hair transplantation are not aesthetically acceptable by today's standards. This is especially true in the face of progressive hair loss, which can unmask previously camouflaged cornrow plugs. A technique to reduce the plugs and recycle the grafts into smaller grafts is described. The recycled hair grafts can be combined with scalp lifting, scalp reductions, and occipital harvesting of grafts to improve the results of cornrow appearing hair transplants and other problems of surgical hair restoration.

online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10744248&dopt=Abstract

Res Vet Sci. 1986 Mar;40(2):212-8.
Effect of biotin supplementation of a barley-wheat diet on restoration of healthy feet, legs and skin of biotin deficient sows.

Misir R, Blair R.

Sixteen sows with induced biotin deficiency were divided into groups of four and fed an egg-white-free barley-wheat based diet without added biotin (control) or supplemented with one of three levels of synthetic d-biotin (100, 200 or 400 micrograms kg-1) for two parities in order to determine the optimal level required to reverse symptoms of the deficiency and to evaluate the relationship among dietary biotin levels, stage of recovery and serum biotin concentrations. Biotin supplementation significantly reduced (P less than 0.05) the incidence of lesions (on the foot pads, above the dew claws and on the skin) and also dry skin, but had no effect (P greater than 0.05) on hoof cracks, hair score or hair density. Time after supplementation had significant effects on reversal of most biotin deficiency symptoms. Interactions between biotin supplementation and time after supplementation suggested that these symptoms were reversed more quickly when higher levels of biotin were fed. Serum biotin concentrations of biotin-supplemented sows were increased with time and exceeded 600 ng litre-1 after 0.5, 1.0 and 1.5 months following biotin supplementation of the basal diet with 400, 200 and 100 micrograms kg-1. In contrast, serum biotin concentrations of the control sows remained low and peaked at 411 ng litre-1 after 2.5 months. The data suggested that supplementation of a barley-wheat diet to provide 147 to 217 micrograms available biotin kg-1 might be adequate to restore healthy feet, legs and skin and concurrently maintain high serum biotin concentrations.

online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3704339&dopt=Abstract

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