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References: Hair growth and hair loss







J Cutan Laser Ther. 2001 Mar;3(1):3-7.
Hair removal with a combined light/heat based photo-epilation system.

Goldberg DJ, Silapunt S.

Skin Laser & Surgery Specialists of New York & New Jersey, Westwood, NJ 07675, USA.

BACKGROUND: A variety of lasers and light sources have been used for removal of unwanted hair. A novel, new, flashlamp-based device, with a mechanism of action based on a combination of both emitted light and heat, has been developed for safe and reliable hair removal. OBJECTIVE: To assess the efficacy and safety of hair removal by a combined light/heat based photoepilation system. METHODS: A pilot trial was undertaken. Twenty one anatomic sites received one to three treatments with the SpaTouch light/heat based photoepilation system. Fluences ranging from 6.25 to 6.45 J/cm(2) and pulse duration of 35 ms were used. Evaluations of hair regrowth was performed at 4 months after the last treatment by comparing the terminal hair count to the baseline values. Patient satisfaction and potential complications were evaluated. RESULTS: Average hair reduction after photoepilation was 27% for one to three treatments at 4 months following the final treatment. 46% and 15% of subjects reported being 'mildly pleased' and 'very pleased' with the results of treatment. No hyperpigmentation, hypopigmentation or scarring was observed at 4 months after treatment. CONCLUSION: The SpaTouch light/heat based photoepilation system represents the newest efficient and safe method in hair removal. Further study of optimal parameters is required.

online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11788098&dopt=Abstract

cvm.tamu.edu

The effects of hypothyroidism on canine skin were determined by comparing morphologic, morphometric, and hair cycle differences in skin biopsy samples from 3 groups of age- and gender-matched Beagle dogs: (1) euthyroid dogs; (2) dogs made hypothyroid by administration of 131I; and (3) dogs made hypothyroid and maintained in a euthyroid state by treatment with synthetic thyroxine. After 10 months of observation, there was slower regrowth of hair 2 months after clipping in the untreated-hypothyroid dogs. Untreated-hypothyroid dogs had a greater number of follicles in telogen and fewer hair shafts (ie, a greater number of hairless telogen follicles) than did the control group. The control dogs had a greater number of telogen follicles but the same number of hair shafts as the treated-hypothyroid group. Treated-hypothyroid dogs had the greatest number of follicles in the growing stage of the hair cycle (anagen). This study suggests that, at least in Beagles, induced hypothyroidism does not affect the pelage as dramatically as has been described in naturally occurring disease. This is because normal Beagles retain hair shafts in follicles for long periods, and the alopecia of hypothyroidism appears to evolve slowly because of the prolongation of this haired telogen stage. The evaluation of thyroxine-treated hypothyroid dogs demonstrates that thyroid hormone supplementation of Beagle dogs with induced hypothyroidism stimulates hair growth.

online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11817058&dopt=Abstract




Dermatol Surg. 2002 Feb;28(2):118-21.
The effect of different spot sizes on the efficacy of hair removal using a long-pulsed diode laser.

Baumler W, Scherer K, Abels C, Neff S, Landthaler M, Szeimies RM.

Department of Dermatology, University of Regensburg, Regensburg, Germany.

BACKGROUND: In the last years several lasers have proven their efficacy for hair removal. However, little is known about the efficacy of varying the spot size with those lasers.OBJECTIVE: To evaluate the long-term efficacy of hair removal using a diode laser with different spot sizes.METHODS: A long-pulsed diode laser (2 x 60 msec) was used. The spot size was 8 mm, 12 mm, or 14 mm. Twenty consenting volunteers were treated three times at regular intervals of 3 weeks. The ratio of the number of hairs in the treated area to an adjacent area left untreated (control) was referred to as regrowth.RESULTS: One month after laser treatment, regrowth was 23% (8 mm), 12% (12 mm), and 13% (14 mm). After 3 months regrowth was 67% (8 mm), 54% (12 mm), and 55% (14 mm). Fifteen months after treatment 4 of 16 volunteers had a regrowth rate of less than 25%.CONCLUSION: The results provide evidence for an effective and long-lasting growth delay of hairs using the long-pulsed diode laser. The use of large spot sizes improved the growth delay of hairs measured 1 month after treatment.

online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11860420&dopt=Abstract [PubMed - in process]





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