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References: Hair growth and hair loss







J Clin Oncol. 1985 Nov;3(11):1471-7.
VP-16 and cisplatin as first-line therapy for small-cell lung cancer.

Evans WK, Shepherd FA, Feld R, Osoba D, Dang P, Deboer G.

Thirty-one patients with small-cell lung cancer (SCLC) were treated with VP-16 and cisplatin as first-line therapy. In the majority of cases an Adriamycin (Adria Laboratories, Columbus, Ohio) containing regimen was contraindicated because of severe cardiac or hepatic disease. Eight patients who presented with cerebral metastases were also included in the series. Eleven patients had limited disease (LD), and 20 had extensive disease (ED). Of the 28 evaluable patients, 12 (43%) achieved a complete response (CR) and 12 (43%) had a partial response (PR). Four patients (14%) either had no response or progressed on treatment. The median duration of response for patients with LD was 39 weeks and for those with ED, 26 weeks. The median survival time (MST) for the whole group of responding (CR and PR) LD patients was 70 weeks (range, 28 to 181 + weeks), and for responding ED patients, it was 43 weeks (range, 17 to 68 weeks). Gastrointestinal toxicity was mild, but leukopenia and thrombocytopenia were common. There were four febrile episodes during periods of drug-induced neutropenia and this led to one treatment-related death. Nephrotoxicity occurred in 15 patients and required discontinuation of cisplatin in two. These results compare favorably with reports of standard induction chemotherapy regimens and provide further evidence of the activity of the VP-16 and cisplatin regimen in patients with SCLC.

online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2997406&dopt=Abstract




Cutis. 1984 Oct;34(4):391-3.
Refining the hair-bearing flap.

Stough DB 3rd, Dean AJ Jr, Abide JM.

The availability of hair-bearing flaps offers patients a more extensive choice of corrective procedures for baldness. The hair-bearing axial temporoparietal-occipital (TPO) flap which we prefer is based on the superficial temporal artery and extends well past the posterior midline. The procedure is performed in the office. The "instant" and exceptionally dense hair which grows in patients with sparse, limited, and finely textured hair is a distinct advantage over the hair transplanted by punch autograft technique. Since the surgery involved is formidable, the patient must be highly motivated, well-informed and advised realistically about the results available with this procedure. A well-planned and properly executed TPO flap procedure is the best method for obtaining the density of hair and the appearance desired within the shortest time.

online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=6488892&dopt=Abstract




Aesthetic Plast Surg. 1995 Jan-Feb;19(1):41-7.
Bilateral temporoparietal flaps in the treatment of male baldness.

Ezaki T, Kasori Y.

Ezaki Clinic, Tokyo, Japan.

This article presents the bilateral temporoparietal flap method for treating frontal baldness. In this procedure symmetrical flaps 2.0-3.0 cm wide are moved from the hairy temporoparietal region to the frontal part of the head and joined in the middle. The surgery can be done simply with no delays and under local anesthesia. The hair on both flaps grows upward, but it covers the top of the head to give it a thick feeling.

online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=7900555&dopt=Abstract





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