References: Hair growth and hair loss
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A total of 80 Kuwaiti children with alopecia areata (AA), without clinical evidence of thyroid disease, were screened for the presence of thyroid abnormalities, and 50 unrelated children with AA were tissue typed for human leukocyte antigen (HLA) class I and class II antigens. Thyroid abnormalities were detected in 14 children (17.5%). Among these, 11 children (14%) had thyroid autoantibodies. These observations highlight the significance of screening for thyroid abnormalities in children with chronic, recurrent, and/or extensive disease. The Kuwaiti children with AA were observed to have a significant association with HLA B21 (OR 18.850, 95% CI 4.404-80.677), B40 (OR 6.767, 95% CI 1.818-25.181), and HLA B12 (OR 4.833, 95% CI 1.198-19.505) antigens. These findings differed from those reported elsewhere.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12437547&dopt=Abstract
Panminerva Med. 1995 Sep;37(3):129-32.
Effects of ozonized autohaemotherapy on human hair cycle.
Riva Sanseverino E, Castellacci P, Misciali C, Borrello P, Venturo N.
Institute of Human Physiology, University of Bologna, Italy.
The present paper deals with the effects of ozonized autohaemotherapy on the human hair cycle in subjects suffering from androgenetic alopecia. The microscopic observation of hairs (trichogram) of 42 subjects (age range = 17-40 years) was carried out before and after cycles of ozonized autohaemotherapy according to the European scientific protocol. The dosage of ozone was 2500-3000 micrograms for each treatment, one cycle consisting of 16 treatments. Results showed a marked improvement of the hair cycle.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8869367&dopt=Abstract
Dig Dis Sci. 1999 Jul;44(7):1428-33.
Celiac disease and autoimmune endocrinologic disorders.
Kaukinen K, Collin P, Mykkanen AH, Partanen J, Maki M, Salmi J.
Department of Internal Medicine, Tampere University Hospital, Finland.
Patients with insulin-dependent diabetes mellitus, autoimmune thyroid disease, Addison's disease, and alopecia areata are at increased risk of celiac disease. We investigated whether patients with more than one autoimmune endocrinologic disorder are even more susceptible to celiac disease or have celiac-type mucosal inflammation. All 62 patients found to have such multiple diseases in 1994-1996 were investigated. Small bowel biopsy was performed on all voluntary nonceliac subjects. The villous structure and density of intraepithelial lymphocytes were examined, and HLA-DQ alleles were determined. Seven (11%) patients had celiac disease: six cases were detected earlier and there was one new case; in addition, two had minor villous deterioration and five an increased density of mucosal intraepithelial gammadelta+ T-cells. HLA-DQ2 or DQ8 alleles were found in all subjects with mucosal changes. Patients with multiple autoimmune disorders clearly run an increased risk of developing celiac disease, and some of them have minor mucosal changes compatible with the early signs of the disease.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10489930&dopt=Abstract
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