References: Hair growth and hair loss
J Wildl Dis. 1986 Oct;22(4):502-10.
Tick (Dermacentor albipictus)-induced winter hair-loss in captive moose (Alces alces).
McLaughlin RF, Addison EM.
Ontario Ministry of Natural Resources, Wildlife Research Section, Maple, Canada.
Five captive moose calves each infested with 42,000 larval Dermacentor albipictus, six calves each infested with 19,000-21,000, and five control moose were observed for changes in hair-loss, body condition and number, stages, and distribution of the tick. Winter hair-loss was observed only in moose infested with ticks and was correlated positively with the total number of adult ticks. Hair-loss associated with ticks was minimal from October to January, but rapidly increased from February to April when up to 44% of hair had been removed. The pattern of hair-loss was similar in all moose with the neck, shoulders, withers, and perianal areas losing the most hair. Moose with extensive premature hair-loss had less pericardial and abdominal visceral fat than moose with little or no hair-loss.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3503137&dopt=Abstract
J Cutan Pathol. 1975;2(5):240-5.
Cellular activity in the dermis surrounding the hair bulb in alopecia areata.
Pierard GE, De la Brassinne M.
The metabolic activity of the cells in the connective tissue surrounding the hair bulb has been studied by radioautography in alopecia areata and in normal scalp, using in vitro incorporation of tritiated thymidine, uridine, histidine, leucine and proline. In alopecia areata, the hair bulbs are blocked in the anagen IV stage and DNA, RNA and protein synthesis are restrained. Cells in the papilla, as well as the cellular infiltrate, display a very low rate of metabolic activity. During regrowth in alopecia areata, the activity of endothelial cells is increased in the papillary and peribulbar layers before DNA, RNA and protein synthesis are restored in the epithelial cells of the hair bulb. The dermal and epithelial labelling patterns eventually reach levels comparable to those observed in an induced anagen IV state of a normal scalp. It is concluded that the progression from anagen IV to a further stage represents a critical period in the growth of hair that would closely depend upon an adequate metabolic function of the connective tissue. It is impaired in alopecia areata.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1214022&dopt=Abstract
Br J Dermatol. 1997 Mar;136(3):315-8.
Diseases associated with dermatitis herpetiformis.
Reunala T, Collin P.
Department of Dermatology, University of Helsinki, Finland.
We have studied the occurrence of associated diseases in a cohort of 305 patients with dermatitis herpetiformis (DH) followed up for a mean of 10 years. The results were compared with those from 383 patients with coeliac disease (CD). Twenty-nine (9.5%) patients with DH and 73 (19.1%) with CD had concomitant endocrine or connective tissue disorders. The following associations were found: auto-immune thyroid disease (4.3% of DH patients and 6.0% of CD patients), insulin dependent diabetes (1.0% DH and 5.5% CD), lupus erythematosus (1.3% DH and 0.3% CD), Sjogren's syndrome (1.0% DH and 2.9% CD), sarcoidosis (1.3% DH and 1.8% CD), and vitiligo or alopecia areata (1.6% DH and 0% CD). We have shown that patients with DH are similar to those with CD in that many have associated endocrine or connective tissue disorders. Most of these diseases began before DH had been diagnosed suggesting that those on a gluten-free diet are not at special risk of contracting them.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9115907&dopt=Abstract
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