References: Hair growth and hair loss
Dermatol Surg. 1997 Sep;23(9):752-5.
A "crush study" review of micrograft survival.
Greco JF, Kramer RD, Reynolds GD.
Appearances Cosmetic Surgery, Venice, FL 34285, USA.
BACKGROUND: Poor growth has been reported after densely packed megasessions. These reports have been fairly consistent. Despite these statements, excellent growth is seen in the majority of their cases. The author's have theorized that iatrogenic trauma from inappropriate graft handling is one etiology that substantially contributes to poor growth. OBJECTIVE: The purpose of this preliminary "crush study" is to: 1) ascertain if follicular trauma directly causes a decreased growth; and 2) consider contributing factors and ways to decrease the incidence of trauma. RESULTS: Initial observations indicate that follicles demonstrate excellent growth, but reduced yields have been noted with less skilled technicians. It appears that graft injury is easily induced with micrografts. CONCLUSIONS: Our findings demonstrate that trauma may increase in direct proportion to the removal of dermis and subcutaneous tissue.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9311368&dopt=Abstract
Dermatol Surg. 1997 Sep;23(9):757-61; discussion 762.
Micrograft size and subsequent survival.
Seager DJ.
Centenary Health Centre, Scarborough, Ontario, Canada.
BACKGROUND: Micrograft survival rates in hair transplantation have been frequently described in private conversations by hair transplant doctors as variable at best. References in medical literature may grossly underestimate the prevalence and magnitude of poor growth. This is probably because most hair transplant surgeons are concerned that publication of a significant incidence of poor growth would reflect negatively on their practice. OBJECTIVES: The purpose of this research was to study micrograft survival rates using microscopic dissection techniques. The author also presents a hypothesis regarding the relatively poor survival rates reported by hair transplant physicians. METHODS: Two different groups of micrografts were prepared. One group, mainly single-haired with tissue trimmed close to the hair shaft, was planted into one test patch in the bald crown of a patient's scalp. Another group of intact follicular clumps, prepared with more dermis, subcutaneous fat, and intact sebaceous glands, was planted into another test patch. These test patches and their growth were documented with close-up photography. RESULTS: The micrografts prepared as existing follicular clumps had a much higher survival rate (over 100%) than the micrografts cut as slender single hairs. CONCLUSIONS: Extremely high survival rates of micrografts are obtainable by transplanting intact follicular clumps with protective tissue around the micrograft, and preserving the follicular clump's sebaceous gland. These survival rates were not achieved when micrografts were produced by splitting individual hairs away from a naturally occurring follicular clump.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9311369&dopt=Abstract
Dermatol Surg. 1997 Sep;23(9):771-84; discussion 801-5.
Follicular transplantation. Patient evaluation and surgical planning.
Bernstein RM, Rassman WR.
New Hair Institute, Los Angeles, California, USA.
BACKGROUND: Follicular transplantation is a method of hair restoration surgery that uses hair in its naturally occurring groups called follicular units. By using the follicular unit exclusively in the transplant, the surgeon can move extensive quantities of implants in a single session to complete the hair restoration in as few sessions as possible. OBJECTIVE: To briefly review the salient features of follicular transplantation, to discuss how the patient should be evaluated for the follicular transplant procedure, and to provide guidelines for the planning of the first and subsequent transplant sessions. This paper will examine: 1) ways to anticipate future hair loss, 2) how to assess donor reserves, 3) what can be accomplished in a single transplant session, 4) how to plan for subsequent sessions, and 5) how to manage the patient with diffuse androgenetic alopecia. METHODS: Follicular transplantation is performed according to techniques detailed in a previous publication (Bernstein et al. Int J Aesthet Rest Surg 1995;3:119-32). RESULTS: Excellent cosmetic results can be achieved when there is meticulous attention to transplanting intact follicular units, when the extent of balding is accurately assessed, and when the finite nature of the donor supply is respected. CONCLUSIONS: Because of their small "physiologic" size, follicular implants enable the surgeon to transplant large numbers in a single session. Follicular transplantation will greatly increase the benefits of the hair restoration procedure when the patient is thoroughly evaluated and when the procedure is undertaken after careful short- and long-term planning.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9311372&dopt=Abstract
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