References: Hair growth and hair loss
Antibiot Khimioter. 1997;42(3):20-4.
[Normalization of intestinal microflora and the general condition of mice of the JCR line as affected by Bifidobacterium concentrate]
[Article in Russian]
Baibakov VI, Karikh TL, Borukaeva LA, Duben' LG, Il'in VP.
It was shown experimentally that the use of liquid Bifidobacterium concentrate (B. bifidum 791 and B. adolescentis MS-42) led to normalization of microflora in mice which resulted in the improvement of the animal general state: increase of body weight, lower death rate, decreased late embryonic mortality, better hair growth.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9265462&dopt=Abstract
channing.harvard.edu
The Nurses' Health Study was initiated in 1976 to study the relation between oral contraceptives and breast cancer. Subsequent funding was available to follow the cohort to address relations between cigarette smoking, postmenopausal hormones, hair dyes, and a range of cancers including breast, endometrial, ovarian, and lung cancer. The 121,700 participating nurses are followed up every 2 years via mail questionnaire to update exposure information to identify incident cancers and other illnesses. Follow-up through 1994 has achieved 90% response from living cohort members. Over the course of the study, additional exposures have been added and refined, including weight at age 18, current weight, height, waist and hip measurements and history of major voluntary weight loss among others. Our focus has been on the health effects of weight gain during middle age. The results relating to diabetes, coronary heart disease, certain types of cancer and total mortality are reviewed. Our primary analytic tools have been multiple logistic regression and Cox proportional hazards models. These methods allow for flexibility in defining the exposures of interest as well as determining their relative importance while controlling for key risk factors. Our models show that even moderate weight gain after age 18 increases risk of each condition. The benefits of physical activity include reduced risk of disease. Issues in the measurement and validation of weight and activity highlight the complexities that are inherent in observational studies addressing the health consequences of lifestyles and anthropometric variables. Our experience of working with repeated measures of body weight and recreational activity are described. Recreational activity has been ascertained in various ways on several questionnaires and may be subject to misclassification. For both weight and activity it may be the pattern of these values that is of importance (e.g. "weight cycling") for some outcomes or conditions. Our research in this area is ongoing. These issues regarding longitudinal measurement will never be completely resolved because weight and activity are intrinsically complex concepts. For these and other such variables, the primary solution is to minimize the problems associated with longitudinal studies. This is best accomplished by developing and maintaining a very strong study design/protocol, including: careful consideration of the sample frame and sample size; maintenance of a high response rate; and continuous monitoring and improvement of the survey/interview instrument(s).
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9272843&dopt=Abstract
Br J Dermatol. 1997 Jul;137(1):24-30.
Characterization of LHTric-1, a new monospecific monoclonal antibody to the trichocyte keratin Ha1.
Westgate GE, Tidman N, De Berker D, Blount MA, Philpott MP, Leigh IM.
Biosciences Division, Unilever Research, Sharnbrook, Bedford, U.K.
The hair follicle is a heterogeneous tissue involving differentiation of both hair forming (trichocyte) and non-hair forming (root sheath) cells; while there are many antibody markers available which can determine the distribution of 'soft' epithelial keratins, fewer have been described which are truly monospecific for hair specific 'hard' keratins. We employed the proven strategy of raising monoclonal antibodies to a short synthetic peptide from the carboxy-terminal sequence of mouse Ha1 and report here the successful production of a monospecific monoclonal antibody which we have called LHTric-1. We have characterized the antibody using immunostaining on rat and human tissues and by immunoblotting against an extract of human follicles. The antibody cross-reacted between rat and human tissue but did not stain formalin-fixed tissue. LHTric-1 localized very specifically to the pre-cortical region of the hair follicle in early anagen and to pre-cortical cells in the upper bulb in anagen. Telogen follicles did not react. LHTric-1 immunoreacted within tongue and nail, staining being restricted to the mid-line above the connective tissue core in tongue and to the suprabasal layers of the nail matrix. The antibody did not react with the fully keratinized hair or nail plate. Finally, in immunoblotting, LHTric-1 reacted with a single band of 44 kDa, suggesting that a single protein was recognized. We conclude that this antibody, by virtue of its known antigen sequence specificity, will be useful in research into the formation of hair and nail in normal and diseased states.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9274621&dopt=Abstract
Lipitor
Herbs and Pharmaceuticals Online ||
Hair Million herbal formula for hair loss and hair growth ||
Hair growth research references ||