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References: Laxative

temp/constipation-1.matches:astrazeneca.com

BACKGROUND: Symptoms of heartburn has an impact on health-related quality of life (HRQL). When a questionnaire is translated into a new language, a linguistic validation is necessary but not sufficient unless the psychometric characteristics have been verified. The aim is to document the psychometric characteristics of the German translation of the Gastrointestinal Symptom Rating Scale (GSRS) and Quality of Life in Reflux and Dyspepsia (QOLRAD) questionnaire. METHODS: 142 patients with symptoms of heartburn (Age: M = 47.5, +/- 14.6; Males = 44.4%) completed the German translation of GSRS, the QOLRAD, the Short-Form-36 (SF-36) and the Hospital Anxiety and Depression (HAD) scale. RESULTS: The internal consistency reliability of GSRS ranged from 0.53-0.91 and of QOLRAD from 0.90-0.94, respectively. The test-retest reliability of GSRS ranged from 0.49-0.73 and of QOLRAD from 0.70-0.84. The relevant domains of the GSRS and QOLRAD domain scores significantly correlated. GSRS domains of Abdominal Pain and Constipation correlated (negatively) with most of the domains of the SF-36. The relevant QOLRAD domains significantly correlated with all SF-36 domains. CONCLUSIONS: The psychometric characteristics of the German translation of GSRS and QOLRAD were found to be good, with satisfactory reliability and validity. The reliability of the GSRS Abdominal Pain domain was moderate.

online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14613560&dopt=Abstract [PubMed - as supplied by publisher]

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Turk J Gastroenterol. 2003 Jun;14(2):128-31.
Irritable bowel syndrome prevalence in city center of Sivas.

Karaman N, Turkay C, Yonem O.

Department of Internal Medicine, Cumhuriyet University, Sivas, Turkey.

BACKGROUND/AIMS: We planned to determine irritable bowel syndrome prevalence in our region with its distribution according to clinical characteristics of patients and the factors which are considered to be related with irritable bowel syndrome. METHODS: 998 of 1250 individuals (mean age 38.99+0.44) replied to our questionnaire including Rome II criteria. RESULTS: We found the irritable bowel syndrome prevalence in the city center of Sivas to be 19.1%. Distribution of irritable bowel syndrome (+) patients age groups showed no significant difference but irritable bowel syndrome was significantly more common in females. The most common occupation showing irritable bowel syndrome positivity was workers. Irritable bowel syndrome prevalence was also significantly higher in persons not eating three regular meals per day. There was a significantly positive correlation between irritable bowel syndrome prevalence and psychological events, previous abdominal operations and infections. A change in bowel habitus was observed in 41.8% of irritable bowel syndrome patients, and the most common change was constipation. 39.8% of the irritable bowel syndrome patients had applied to the doctor, most often to doctors of internal medicine. We found the irritable bowel syndrome prevalence not to be related with educational status, smoking, daily tea and coffee consumption, alcohol intake, menstrual periods or weight loss. CONCLUSION: Irritable bowel syndrome prevalence in our region with its demographic characteristics was similar to the results seen in western countries.

online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14614640&dopt=Abstract

temp/constipation-1.matches:medschl.cam.ac.uk

OBJECTIVES: Psychosocial factors have been examined in functional bowel disorders (FBD), including irritable bowel syndrome (IBS) and chronic idiopathic constipation (CIC). Abnormal illness behaviour (AIB) has been investigated in IBS patients as evidence of underlying psychological distress and as influencing health-care-seeking behaviour. Health locus of control may also contribute to health-care-seeking behaviour, as possession of an external locus of control places responsibility for health status onto professionals. Thus, external locus of control may also be more prominent in FBD patients. This study examined whether FBD patients displayed more AIB and an external health locus of control compared with organic disease and non-patient controls. DESIGN: A cross-sectional comparison group design was employed. METHOD: Fifty-three CIC patients were compared with matched control groups of 50 IBS patients, 51 Crohn's disease patients and 53 non-patient participants. Questionnaire measures included the Illness Behaviour Questionnaire, the Multi-dimensional Health Locus of Control, the GHQ, and the SCL-90R. RESULTS: FBD patients did not differ from Crohn's disease patients on measures of AIB, but all three patient groups differed from non-patient participants. Crohn's disease patients possessed a higher external locus of control compared with FBD patients and non-patient controls. There was a general association between AIB and psychopathology. CONCLUSIONS: FBD patients did not report more AIB or a higher external locus of control regarding their health status, compared with organic disease controls, but did differ from non-patients. The presentation of AIB was related to increased psychopatholog

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