References: Laxative
temp/constipation-1.matches:
Rev Gastroenterol Disord. 2003;3 Suppl 3:S32-42.
Irritable bowel syndrome: a primer on management.
Lacy BE.
Marvin M. Schuster Center for Digestive and Motility Disorders, Johns Hopkins University School of Medicine, Baltimore, MD.
Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder characterized by abdominal pain, bloating, and either constipation or diarrhea. Managing this chronic condition requires a coordinated effort between patient and physician. The diagnosis of IBS should be made as early as possible in the evaluation of a patient, so that treatment can be initiated as soon as possible. Treatment usually requires a multifactorial approach, including patient education, reassurance, lifestyle changes, and pharmacotherapy. In this article, medications commonly used to treat the individual symptoms of IBS are reviewed, based on evidence from the literature. In addition, new agents that affect the serotonin system and treat the global symptoms of IBS are described.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14502115&dopt=Abstract [PubMed - in process]
temp/constipation-1.matches:
Neurogastroenterol Motil. 2003 Oct;15(5):515-22.
Colonic motor activity in slow-transit idiopathic constipation as identified by 24-h pancolonic ambulatory manometry.
Hagger R, Kumar D, Benson M, Grundy A.
Department of Surgery, St George's Hospital, Tooting, London, UK.
Colorectal motor activity in slow-transit idiopathic constipation has not been fully evaluated under physiological conditions. The aim of this study was to evaluate colorectal motor activity in chronic idiopathic constipation using 24-h ambulant pancolonic manometry. Ten healthy volunteers (six females) 19-31 years of age, and eight females 25-46 years of age with slow-transit idiopathic constipation were studied. Motor activity was measured using two custom-made silicone-coated catheters, each with five solid-state pressure transducers. Bowel preparation or sedation was not used. Frequency of high-amplitude propagated contractions was reduced in chronic idiopathic constipation, median 1.9/24 h vs 6/24 h (P = 0.01). Contractile frequency of low-amplitude complexes was reduced throughout the colon in slow-transit idiopathic constipation (P < 0.0001). The interval between contractile complexes was reduced in the transverse colon and splenic flexure (P < 0.0001). This study demonstrates that colonic motor activity is abnormal in slow-transit idiopathic constipation; decreased motor activity leads to a reduction in propulsion of intraluminal contents.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14507351&dopt=Abstract
temp/constipation-1.matches:tiho-hannover.de
In a study with sows at various stages of the reproductive cycle, the effects of parturition, feed quantity and composition (content and type of crude fibre), exercise and access to water on dry matter content, and consistency of faeces were estimated. Parturition caused an increase in the dry matter content and reduced the defaecation frequency. The restriction of feed amounts in the last days of gestation and the change to lactation feed with reduced crude fibre content (6-3% in feed) intensified the physiologically occurring increase of the dry matter content. Moving activity and the amount of water ingested had only a small insignificant effect on the moisture of the faeces. The faeces became markedly softer when large amounts of fermentable fibre were used in the diet. The risk for constipation in periparturient sows increases when feed amounts and fibre content in the diet are strongly reduced. Therefore, it is recommended to offer sows daily minimum amounts of a diet (<2 kg) containing >7-8% crude fibre (including a highly fermentable fibre to improve faeces consistency) especially on the days near parturition.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14511136&dopt=Abstract
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