References: Laxative
temp/constipation-14.matches:
J R Soc Med. 1984 Jul;77(7):559-63.
Outlet syndrome: is there a surgical option?
Keighley MR, Shouler P.
Of 46 patients investigated for constipation, 21 were found to have some other primary abnormality, leaving 25 patients for study: 6 had evidence of the outlet syndrome alone, 5 had slow transit constipation, 8 had both abnormalities and 6 had no apparent physiological disorder in the colon or rectum. Although colectomy and ileorectal anastomosis gave good results for slow transit constipation, partial pelvic floor division provided satisfactory long-term improvement in only one of the 7 patients with the outlet syndrome.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=6747979&dopt=Abstract
temp/constipation-14.matches:
Monatsschr Kinderheilkd. 1984 May;132(5):258-63.
[Late study results following megacolon operations]
[Article in German]
Holschneider AM.
The basic pathophysiologic disturbance in Hirschsprung's disease is a functional obstruction caused by defective intramural nerve supply and by internal anal sphincter achalasia. Therapy consists in resecting the dysganglionic bowel segment. In each case however an aganglionic segment of different length and an internal analsphincter with a different degree of achalasia remain in situ. Therefore the postoperative results are dependant on an equilibrium between the proximal normal innervated colon and the length and function of the remaining aganglionic and achalic parts of the rectum and anal canal. In about one third of all patients with Hirschsprung's disease disturbances of this equilibrium postoperatively lead to enterocolitis, encopresis, or chronic constipation. Five years later however the authors could observe enterocolitis in only 7.3% chronic constipation in 9.5% and encopresis in 13.9% of their operated patients. With increasing time after operation there is a growing tendency towards the spontaneous regeneration. Therefore, the prognosis of Hirschsprung's disease is very good: about 90% of all cases can be cured.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=6749149&dopt=Abstract
temp/constipation-14.matches:
Gastroenterology. 1983 Apr;84(4):737-40.
Colonic electromyography in chronic constipation.
Frieri G, Parisi F, Corazziari E, Caprilli R.
Myoelectric activity of the sigmoid has been studied in 12 patients with chronic nonorganic constipation and 10 control subjects. All patients showed total gastrointestinal transit time longer than 96 h, with left-colonic or rectocolonic slowed transit. Electrical and mechanical activity was recorded by means of an intraluminal probe with bipolar suction electrodes and open-ended tips. Two groups of frequencies of slow waves, a slower rhythm at approximately 3 cycles/min and a faster rhythm at approximately 6 cycles/min were recorded in patients and control subjects. The mean frequency of the slower rhythm was significantly (p less than 0.005) higher in patients with constipation than in control subjects, whereas the frequency of the faster rhythm and the incidence of both rhythms were similar in the two groups. Mechanical activity showed no difference in terms of motility index and percentage of activity between patients and control subjects. Results of the study indicate that patients with left colonic constipation show an increase in frequency of the slower colonic rhythm in the very segment in which slowing down of transit occurs. It is suggested that the higher slow-wave activity in the sigmoid induces an increase in segmenting contractions and therefore may be responsible for the slowing down of intestinal transit.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=6825984&dopt=Abstract
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