References: Hair growth and hair loss
Ann Dermatol Venereol. 1988;115(4):451-3.
[Physiopathological approach to seborrhea of the scalp]
[Article in French]
Pierard-Franchimont C, Pierard GE.
Service de Dermatologie, CHU du Sart Tilman, Liege.
Objective assessment of seborrhea of the scalp has seldom been reported in the literature. We have used a variant of the method described by Saint-Leger and Leveque to measure the sebum excretion rate in normal scalp, male pattern alopecia, pityriasis amiantacea, pityriasis capitis and alopecia areata. The sebum excretion rate was significantly increased in male pattern alopecia, significantly decreased in pityriasis amiantacea and showed a trend towards reduction in alopecia areata. Pityriasis capitis was not associated with changes in the excretion of sebum.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2970818&dopt=Abstract
Br J Dermatol. 1988 Dec;119(6):723-30.
Clinical markers of androgenicity in acne vulgaris.
Sheehan-Dare RA, Hughes BR, Cunliffe WJ.
Department of Dermatology, General Infirmary, Leeds, U.K.
Androgenic stimulation of sebaceous glands is necessary for development of acne. If hyperandrogenaemia were a major determinant of acne in women, the frequency of other clinical markers of androgenicity should increase with acne severity. To investigate this, 268 female subjects (aged 12-44 years) were studied. Subjects were divided into groups on the basis of acne severity: physiological, moderate, and severe. With exclusion of women taking oral contraceptives or anti-androgen therapy, subjects in each group were similar with respect to age at menarche and incidence of menstrual irregularity of amenorrhoea. Reports of excessive body hair, and clinical hirsutes on examination were few and there were no significant differences between acne severity groups. No correlation was observed between acne and hirsutes grades in all subjects (rank correlation coefficient = 0.096). Mild male pattern androgenic alopecia occurred in similar proportions of subjects in the three groups. Female pattern androgenic alopecia was observed in only two subjects. We have shown no correlation between acne severity and clinical markers of androgenicity in women. This suggests that in most cases factors other than hyperandrogenaemia are necessary for the development of acne.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2974304&dopt=Abstract
J Korean Med Sci. 1987 Sep;2(3):157-65.
A clinical study of topical mucopolysaccharides & polydeoxyribonucleoprotein (Foltene) therapy in alopecia.
Lee KS, Myung KB, Kook HI.
Department of Dermatology, College of Medicine, Ewha Womans University.
We performed clinical trials to evaluate the therapeutic effects of Foltene in patients of the several types of hair fallings. Thirty patients with male pattern baldness, alopecia areata and seborrheic alopecia were included in this study. Foltene was applied every other day for 40 days, and followed by maintenance therapy of twice application a week. The duration of whole therapy was 6 months. We conclude that Foltene is an effective and agent for male pattern baldness, alopecia areata and seborrheic alopecia from the following results. Ten patients with male pattern baldness was treated with Foltene for 6 months. Foltene had therapeutic effects of 50% in hair regrowth, 70% in decreased hair falls, 30% in decreased dandruff, 50% in decreased seborrhea. Thirteen patients with alopecia areata was treated with Foltene for 6 months. Foltene had therapeutic effects of 61.6% in hair regrowth, 53.9% in decreased in hair falls, 53.9% in decreased dandruff, 77.0% in decreased seborrhea. Seven patients with seborrheic alopecia was treatment with Foltene for 6 months. Foltene had therapeutic effects of 85.8% in hair regrowth, 57.2% in decreased hair falls, 42.9% in decreased dandruff, 85.8% in decreased seborrhea. The degree of therapeutic success was related to the duration of therapy. The side effects were as followed: itching sensation developed in 2 patients (6.7%); tingling sensation in 3 patients (10.0%); burning sensation in 1 patient (3.3%); erythema in 3 patients (10.0%).
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2978541&dopt=Abstract
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