References: Hair growth and hair loss
Clin Endocrinol (Oxf). 1989 Apr;30(4):459-70.
Heterogeneity of the polycystic ovary syndrome: clinical, endocrine and ultrasound features in 556 patients.
Conway GS, Honour JW, Jacobs HS.
Endocrine Unit, Middlsex Hospital, London, UK.
This paper reports an analysis of the clinical, endocrine and ultrasound data within a population of 556 patients with ultrasound-diagnosed polycystic ovaries. Compared with those not so affected, hirsutism was associated with a higher mean serum testosterone concentration, infertility was associated with higher mean gonadotrophin concentrations, obesity was associated with a higher mean serum testosterone concentration, hyperprolactinaemia was associated with a lower mean serum testosterone concentration and smaller ovaries, alopecia was associated with lower mean serum LH and testosterone concentrations, and acanthosis nigricans was associated with obesity and a raised mean serum testosterone concentration. The heterogeneity illustrates the limitations in the use of specific clinical or endocrine criteria as requirements for the diagnosis of the polycystic ovary syndrome.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2688996&dopt=Abstract
Radiology. 1977 Nov;125(2):497-502.
Combined therapy of osteosarcoma: preoperative irradiation, surgery, and chemotherapy.
Munzenrider JE, Emami B, Tchakarova I, Necheles TF, Banks HH, Paradelo JC, Oh WH.
The rationale for prebiopsy and preoperative irradiation in a multimodal approach to treatment of osteosarcoma is presented. Six patients with osteosarcoma underwent preoperative irradiation, amputation, and elective chemotherapy. Five of these also received prebiopsy irradiation: three survive without metastases at 29, 36, and 56 months, with no therapy for 10, 16, and 37 months, respectively; two patients died at 6 and 19 months of pulmonary metastases which appeared at 2 and 10 months, respectively. The latter two did not receive prebiopsy irradiation. Another patient, whose pulmonary metastasis regressed at 6 months with adriamycin and was later resected, died of cardiac failure at 59 months without evident metastasis. Immunologic aspects of the disease are also discussed.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=269460&dopt=Abstract
Cutis. 1989 Feb;43(2):148-52.
Evaluation of alopecia: a new algorithm.
Modly CE, Wood CM, Burnett JW.
Department of Medicine, University of Maryland Hospital, Baltimore 21201.
The clinical evaluation of alopecia is becoming less precise as more histopathologic correlations become available. According to the classic approach, the clinician should initially differentiate between scarring and nonscarring alopecia. Because several case reports in the past ten years have demonstrated that the definition of "scarring alopecia" is ambiguous, the use of the traditional schema--scarring versus nonscarring--may well be outmoded. Therefore, we propose a new algorithm for the evaluation of alopecia that emphasizes the importance of both clinical and histologic findings.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2702858&dopt=Abstract
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