References: Hair growth and hair loss
Przegl Dermatol. 1989 Sep-Dec;76(5-6):416-21.
[Abnormalities of structure and function of the thyroid in patients with alopecia areata]
[Article in Polish]
Broniarczyk-Dyla G, Lewinski A, Zerek-Melen G, Sewerynek E, Wozniacka A.
In 85 patients with alopecia areata the frequency of thyroid disease was assessed on the basis of history data, clinical examination and determination of T3, T4, TSH and presence of antithyroid antibodies of different specificity (ATMA, ATg, AMD). Among these patients abnormalities of thyroid structure and function were significantly more frequent (78%) than in the control group (33%). In 11% of the patients autoimmune thyroid disease was present (Graves-Basdow disease, Hashimoto thyroiditis). In 86 controls no cases of autoimmune diseases were found. In some patients only a slight enlargement of the thyroid was present (grade OB, I.).
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2641808&dopt=Abstract
Hautarzt. 1989 Feb;40(2):77-83.
[The Brocq pseudopelade--a disease picture or disease entity]
[Article in German]
Braun-Falco O, Bergner T, Heilgemeir GP.
Dermatologische Klinik, Ludwig-Maximilians-Universitat Munchen.
In 1885 Brocq described a type of scarring alopecia he called pseudopelade (PPB), whose character as a separate disease entity has been denied in recent decades. Several authors now believe PPB to be a polyetiological final stage (etat pseudopeladique de Degos; EPP). In all, 142 patients with scarring alopecia were analyzed in an attempt to find whether PPB is a separate entity or not. Following examination, 26 cases with lichen ruber (LR), 18 cases with lupus erythematosus chronicus discoides (DLE), 2 cases with scleroderma, 1 case with folliculitis decalvans, and 1 case with ichthyosis vulgaris were diagnosed; this left 94 cases with PPB (66%). We attempt to describe the macroscopic morphology and histopathology in PPB and in LR and DLE. The findings yielded by direct immunofluorescence and the treatment are discussed.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2654076&dopt=Abstract
Hautarzt. 1989 Feb;40(2):84-9.
[The significance of lymphocytic differentiation antigens in the diagnosis and therapy of alopecia areata]
[Article in German]
Lutz G, Kreysel HW.
Universitats-Hautklinik, Rheinischen Friedrich-Wilhelms-Universitat Bonn.
In an earlier study, a significant reduction of the CD8+, CD16+, CD19+, CD8+Leu8+ and HLA-DQ+ cells was found in the peripheral blood of patients with alopecia areata (AA). On the basis of these findings, typing was repeated after 6 months at the earliest in a total of 44 patients who had meanwhile received different therapies, to detect any shifts in these lymphocyte subgroups with cure or persistence of AA. Any external or internal treatment had been discontinued 4 weeks before typing, in order to preclude short-term influences of the therapy. An increase, i.e., normalization, in CD8+ cells together with a significant decrease in CD4+ cells was shown in the group with complete remission, in contrast to the patients in whom AA had not yielded to treatment. The remaining lymphocyte dysbalances persisted unchanged in both groups. This shows that healing of AA is associated with an increase in CD8+ and a decrease in CD4+ cells.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2654077&dopt=Abstract
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