References: Hair growth and hair loss
Clin Exp Dermatol. 1989 Nov;14(6):429-33.
Juvenile versus maturity-onset alopecia areata--a comparative retrospective clinical study.
De Waard-van der Spek FB, Oranje AP, De Raeymaecker DM, Peereboom-Wynia JD.
We report a retrospective study of 209 patients presenting with alopecia areata (AA) at our skin department during the period 1969-1987, with special reference to possible associations, aetiological factors and the relevance of additional investigations. The patients were divided into two groups: (I) those in whom AA developed during childhood; (II) those in whom AA developed in adult life (greater than or equal to 16 years). The aim of this study was to establish whether there is a difference between juvenile and maturity-onset AA and to consider the value of additional investigations in AA. Juvenile AA is more severe and has a less favourable prognosis than the maturity-onset disease. Statistically significant differences between the two groups were not found with respect to AA type and prevalence of auto-antibodies. Bad prognostic signs in AA were early age of onset, atopy (or first-degree family history) and ophiasis and/or onychodystrophy. Initial thyroid function testing seems advisable in patients with AA. Additional valuable investigations may include hair-root examination, determination of antibodies against thyroid tissue, and serum zinc levels. There are indications that psychosomatic factors may play a role in AA. In our study, psychosomatic factors were found in 29% of the juvenile AA and in 17% of the maturity-onset AA patients.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2605805&dopt=Abstract
J Hered. 1989 Nov-Dec;80(6):493-6.
Hereditary congenital baldness: a sex-linked trait in the domestic fowl.
Somes RG Jr.
Department of Nutritional Sciences, University of Connecticut, Storrs 06268.
Congenital baldness in the domestic fowl is a genetic condition in which small irregular skin areas are devoid of down feathers (and later definitive feathers) over one or both eyes and/or the center of the head. In this study, the expression of congenital baldness was quite variable and ranged in size from a few follicles to areas as large as 10 mm2. The area over the right eye and the center of the head was more frequently involved than was the area over the left eye. This condition was inherited as sex-linked recessive. The symbol ba was assigned to the gene, and it was shown to be linked to the sal locus by 7.6 to 8.2 crossover units. An unusual feature was that 5% to 13% of heterozygous males exhibited the trait.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2614064&dopt=Abstract
Zhonghua Wai Ke Za Zhi. 1989 Sep;27(9):558-60, 575.
[Planning of a local flap of expanded scalp for repair of alopecia cicatrisata]
[Article in Chinese]
Ai YF.
Tissue expansion of scalp opens a new way for the treatment of alopecia cicatrisata. From May 1986 to April 1988, 56 cases of alopecia cicatrisata and skull outcrop had been repaired by Chinese tissue expander in our department. All cases got good results. Of them, the area of alopecia was over 120 cm2 and the greatest one (320 cm2) consisting of two third of the total scalp in 21 cases. There were 49 cases repaired by one expansion and other 7 cases followed by a secondary expansion. The characteristics of the expanded scalp and the common types of local flap design had been discussed. It was applicable for all kinds of alopecia cicatrisata and both for children (over 3 yrs) and adults. The results of scalp expansion in children revealed superior than that in adults. We considered that the repairing of alopecia cicatrisata by scalp expansion had more advantages than other methods.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2630230&dopt=Abstract
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