References: Hair growth and hair loss
J Dermatol Surg Oncol. 1990 Jun;16(6):543-8.
Triple rhomboid flap for crown alopecia correction.
Stough DB, Stough DB.
Stough Dermatology and Dermatologic Plastic Surgery Clinic, Hot Springs, Arkansas.
The triple rhomboid flap offers significant advantages over previously described methods for reducing vertex alopecia. The circular area of alopecia is converted into a hexagon. The hexagon is then excised and closed by rotation of three rhomboid flaps from the hair-bearing periphery. The specific indications for this flap are reviewed, the technical aspects are discussed, and illustrations are provided.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2136523&dopt=Abstract
J Am Acad Dermatol. 1990 Jan;22(1):91-3.
Treatment of androgenic disorders with dexamethasone: dose-response relationship for suppression of dehydroepiandrosterone sulfate.
Redmond GP, Gidwani GP, Gupta MK, Bedocs NM, Parker R, Skibinski C, Bergfeld W.
Department of Endocrinology, Cleveland Clinic Foundation, OH 44195.
Glucocorticoids are effective in suppressing androgens in many women whose levels of these steroids are elevated. Their use has been controversial because of inconsistent reports about efficacy and concern about safety. We investigated the dose-response relationship for suppression of dehydroepiandrosterone sulfate (DHEAS) with the use of dexamethasone. Thirty women with an initial DHEAS value of greater than or equal to 300 micrograms/dl were studied. All had cystic or inflammatory acne, hirsutism, or androgenic alopecia. Dexamethasone was given as a single bedtime dosage of 0.125, 0.250, or 0.375 mg. Mean dosage required for suppression was 0.256 mg daily. Suppression of the DHEAS level to less than or equal to 200 micrograms/dl was achieved with 0.125 mg in 25% of women, 0.250 mg in an additional 50%, and 0.375 mg in a further 20%. Most patients were taking spironolactone when the study was performed. Effective suppression is attained with dexamethasone doses significantly lower than previously thought. Use of these doses was not associated with a significant incidence of adverse effects.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2137141&dopt=Abstract
Dermatologica. 1990;180(1):5-7.
Erythema multiforme-like eruptions: a rare side effect of topical immunotherapy with diphenylcyclopropenone.
Perret CM, Steijlen PM, Zaun H, Happle R.
Department of Dermatology, University of Nijmegen, The Netherlands.
We report 3 cases of erythema multiforme following topical application of diphenylcyclopropenone (DCP) for the treatment of alopecia areata. This eruption represents a rare side effect which could be controlled with corticosteroids given both systemically and topically. When this unusual reaction occurred, treatment with DCP was stopped. In one of the patients, subsequent topical immunotherapy with squaric acid dibutylester was not complicated by this side effect and resulted in complete hair regrowth.
online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2137800&dopt=Abstract
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