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References: Hair growth and hair loss

J Wildl Dis. 1991 Apr;27(2):254-7.
Control of Psoroptes cuniculi in captive white-tailed deer with ivermectin-treated corn.

Garris GI, Prullage JB, Prullage JL, Wright FC, Miller JA.

U.S. Department of Agriculture, Knipling-Bushland U.S. Livestock Insects Research Laboratory, Kerrville, Texas 78029.

Psoroptes cuniculi, the ear mite of domestic rabbits, was collected from captive white-tailed deer (Odocoileus virginianus). This is the first report of rabbit ear mite infestations in white-tailed deer in Oklahoma or Texas (USA). In addition to moderate infestations in their ears, two 4-yr-old bucks, two 3-yr-old does, and seven 4-yr-old does showed patchy areas of alopecia along the sides and brisket. Both bucks also had patchy areas of alopecia around the base of antlers. Ear mites were eradicated from all deer except from one doe by providing ivermectin-treated corn to the deer at a rate of 1,000 g (equivalent to 200 mcg/kg of ivermectin)/day/deer for several days. The ear mite infestation in the one doe was eradicated by intramuscularly injection with ivermectin at 400 mcg/kg. After treatment with the ivermectin and eradication of the mites, the alopecia improved and eventually was eliminated. The ivermectin-treated corn also controlled all internal nematode parasites in the deer.

online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2067046&dopt=Abstract

Oncol Nurs Forum. 1991 May-Jun;18(4):769-73.
Intervening with alopecia: exploring an entrepreneurial role for oncology nurses.

Ehmann JL, Sheehan A, Decker GM.

Johanna's On Call To Mend Esteem for Cancer Rehabilitation Nurse Consultants, Albany, NY.

This article discusses the development of an innovative role for oncology nurses in assisting patients with their personal information and image needs that arise from alopecia secondary to the treatment of cancer. An independent oncology nursing consultative service was initiated after a survey of patients was conducted (N = 40) to assess alopecia knowledge, needs, and referral source. Nurses (N = 16) attending a local Oncology Nursing Society (ONS) chapter meeting were surveyed to assess their intervention patterns and knowledge of hair and scalp care during hair loss. To respond to needs identified through the surveys, the consultative service developed a patient education program and booklet, as well as professional education sessions. Management and evaluation of this practice continues to provide a learning experience.

online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2067965&dopt=Abstract

J Invest Dermatol. 1991 Aug;97(2):345-8.
Effect of androgens on the growth of cultured human dermal papilla cells derived from beard and scalp hair follicles.

Thornton MJ, Messenger AG, Elliott K, Randall VA.

Department of Biomedical Sciences, University of Bradford, West Yorkshire, U.K.

Androgens stimulate hair growth in some areas, e.g., beard, but may cause regression and baldness on the scalp. The mesenchyme-derived dermal papilla is believed to regulate many aspects of hair growth. It is probable that androgens exert their effect on hair growth via the dermal papilla. In this study the effect of androgens on the growth of cultured dermal papilla cells from beard and non-balding scalp was assessed. Dermal papilla cells from beard hair follicles and non-balding scalp were cultured in vitro in the presence and absence of different concentrations of testosterone or the synthetic, non-metabolizable androgen, mibolerone. Cell growth was reflected by the incorporation of 3H-thymidine. The presence of either androgen did not significantly alter DNA synthesis at any of the concentrations examined in either type of cell line. These results do not mean that dermal papilla cells do not respond to androgens in vitro, but that the measurement of cell growth is an inappropriate method of assessment. Androgens may well stimulate the synthesis of specific proteins that could influence the hair follicle.

online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2071943&dopt=Abstract

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